James E. Bear, Ph.D.

Cell and Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
cell migration
"james bear"


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Charles Saxe grad student 1993-1998 Emory
Frank B. Gertler post-doc 2002 MIT (Neurotree)


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Liang Cai grad student 2003-2007 UNC Chapel Hill
Thomas W. Marshall grad student 2009 UNC Chapel Hill
Andrea C. Uetrecht grad student 2009 UNC Chapel Hill
Congying Wu grad student 2013 UNC Chapel Hill
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Tessier S, Doolittle AC, Sao K, et al. (2020) Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight
Miller CJ, LaFosse PK, Asokan SB, et al. (2019) Emergent spatiotemporal dynamics of the actomyosin network in the presence of chemical gradients. Integrative Biology : Quantitative Biosciences From Nano to Macro
Freemerman AJ, Zhao L, Pingili AK, et al. (2019) Myeloid -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. Journal of Immunology (Baltimore, Md. : 1950)
Graham DM, Andersen T, Sharek L, et al. (2018) Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction. The Journal of Cell Biology
Paul DS, Casari C, Wu C, et al. (2017) Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice. Blood Advances. 1: 1398-1408
Zhao L, Cozzo AJ, Johnson AR, et al. (2017) Lack of myeloid Fatp1 increases atherosclerotic lesion size in Ldlr(-/-) mice. Atherosclerosis. 266: 182-189
Rotty JD, Brighton HE, Craig SL, et al. (2017) Arp2/3 Complex Is Required for Macrophage Integrin Functions but Is Dispensable for FcR Phagocytosis and In Vivo Motility. Developmental Cell
Chong DC, Yu Z, Brighton HE, et al. (2017) Tortuous Microvessels Contribute to Wound Healing via Sprouting Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology
Zimmerman SP, Asokan SB, Kuhlman B, et al. (2017) Cells lay their own tracks: optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration. Journal of Cell Science
Shutova MS, Asokan SB, Talwar S, et al. (2017) Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility. The Journal of Cell Biology
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