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James E. Bear, Ph.D.

Cell and Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
cell migration
"james bear"


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Charles Saxe grad student 1993-1998 Emory
Frank B. Gertler post-doc 2002 MIT (Neurotree)


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Liang Cai grad student 2003-2007 UNC Chapel Hill
Thomas W. Marshall grad student 2009 UNC Chapel Hill
Andrea C. Uetrecht grad student 2009 UNC Chapel Hill
Congying Wu grad student 2013 UNC Chapel Hill
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Baldwin SA, Van Bruggen SM, Koelbl JM, et al. (2021) Microfluidic devices fitted with "flowver" paper pumps generate steady, tunable gradients for extended observation of chemotactic cell migration. Biomicrofluidics. 15: 044101
SenGupta S, Parent CA, Bear JE. (2021) The principles of directed cell migration. Nature Reviews. Molecular Cell Biology
Lerner AM, Hepperla AJ, Keele GR, et al. (2020) An optogenetic switch for the Set2 methyltransferase provides evidence for transcription-dependent and -independent dynamics of H3K36 methylation. Genome Research
Harrison EB, Porrello A, Bowman BM, et al. (2020) A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking. Cancer Research
Eckly A, Scandola C, Oprescu A, et al. (2020) Megakaryocytes use in vivo podosome-like structures working collectively to penetrate the endothelial barrier of bone marrow sinusoids. Journal of Thrombosis and Haemostasis : Jth
Tagliatela AC, Hempstead SC, Hibshman PS, et al. (2020) Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion. Scientific Reports. 10: 11958
Nosbisch JL, Rahman A, Mohan K, et al. (2020) Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing. Plos Computational Biology. 16: e1007708
Tessier S, Doolittle AC, Sao K, et al. (2020) Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight
Miller CJ, LaFosse PK, Asokan SB, et al. (2019) Emergent spatiotemporal dynamics of the actomyosin network in the presence of chemical gradients. Integrative Biology : Quantitative Biosciences From Nano to Macro
Freemerman AJ, Zhao L, Pingili AK, et al. (2019) Myeloid -Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. Journal of Immunology (Baltimore, Md. : 1950)
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