Claude Hélène, Ph.D.

Biophysics Muséum d'Histoire Naturelle 
nucleic acids, RNA
"Claude Hélène"
Cross-listing: Chemistry Tree


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Charles Sadron grad student 1966 Universite de Paris (Chemistry Tree)
Richard B. Setlow research scientist 1972 Oak Ridge National Laboratory (Neurotree)


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René Santus grad student 1968 University of Paris (Chemistry Tree)
Marie-Paule Pileni post-doc University of Orléans (Chemistry Tree)
Jean-Louis Mergny research scientist MNHN, Paris, France (Chemistry Tree)
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Ryabinin VA, Boutorine AS, Hélène C, et al. (2004) Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex. Nucleosides, Nucleotides & Nucleic Acids. 23: 953-68
Ryabinin VA, Boutorine AS, Hélène C, et al. (2004) Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes. Nucleosides, Nucleotides & Nucleic Acids. 23: 789-803
Boutorine AS, Ryabinin VA, Novopashina DS, et al. (2003) Stabilization of DNA double and triple helices by conjugation of minor groove binders to oligonucleotides. Nucleosides, Nucleotides & Nucleic Acids. 22: 1267-72
Sun JS, Hélène C. (2003) Oligonucleotides and derivatives as gene-specific control agents. Nucleosides, Nucleotides & Nucleic Acids. 22: 489-505
Arimondo PB, Angenault S, Halby L, et al. (2003) Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates. Nucleic Acids Research. 31: 4031-40
Alberti P, Lacroix L, Guittat L, et al. (2003) Nucleic acids as targets for antitelomerase agents. Mini Reviews in Medicinal Chemistry. 3: 23-36
Vinogradov S, Roig V, Sergueeva Z, et al. (2003) Synthesis and binding properties of oligo-2'-deoxyribonucleotides conjugated with triple-helix-specific intercalators: benzo[e] and benzo[g] pyridoindoles. Bioconjugate Chemistry. 14: 120-35
Alberti P, Arimondo PB, Mergny JL, et al. (2002) A directional nucleation-zipping mechanism for triple helix formation. Nucleic Acids Research. 30: 5407-15
Roulon T, Hélène C, Escudé C. (2002) Coupling of a targeting peptide to plasmid DNA using a new type of padlock oligonucleotide. Bioconjugate Chemistry. 13: 1134-9
Dias N, Sénamaud-Beaufort C, Forestier El El, et al. (2002) RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer. Journal of Molecular Biology. 320: 489-501
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