Ian Ganley

Stanford University, Palo Alto, CA 
"Ian Ganley"
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McWilliams TG, Prescott AR, Allen GF, et al. (2016) mito-QC illuminates mitophagy and mitochondrial architecture in vivo. The Journal of Cell Biology
Stretton C, Hoffmann TM, Munson MJ, et al. (2015) GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling. The Biochemical Journal. 470: 207-21
Petherick KJ, Conway OJ, Mpamhanga C, et al. (2015) Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. The Journal of Biological Chemistry. 290: 11376-83
Bago R, Malik N, Munson MJ, et al. (2014) Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase. The Biochemical Journal. 463: 413-27
Hau AM, Greenwood JA, Löhr CV, et al. (2013) Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells. Plos One. 8: e65250
MacCallum SF, Groves MJ, James J, et al. (2013) Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Scientific Reports. 3: 1275
Nottingham RM, Pusapati GV, Ganley IG, et al. (2012) RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36. The Journal of Biological Chemistry. 287: 22740-8
Nottingham RM, Ganley IG, Barr FA, et al. (2011) RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. The Journal of Biological Chemistry. 286: 33213-22
Ganley IG, Espinosa E, Pfeffer SR. (2008) A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells. The Journal of Cell Biology. 180: 159-72
Reddy JV, Ganley IG, Pfeffer SR. (2006) Clues to neuro-degeneration in Niemann-Pick type C disease from global gene expression profiling. Plos One. 1: e19
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