Luk H. Vandenberghe
Affiliations: | Harvard Medical School, Boston, MA, United States |
Area:
AAV, Vector development, Ocular Gene Transfer, Vaccines, Immunology, Retinal degenerationsGoogle:
"Luk Vandenberghe"Cross-listing: Cell & Gene Therapy Tree - GenetiTree
Parents
Sign in to add mentor| Jean Bennett | grad student | Penn (Cell & Gene Therapy Tree) | |
| Zeger Debyser | grad student | KU Leuven (Cell & Gene Therapy Tree) | |
| Carl H. June | grad student | Penn (Cell & Gene Therapy Tree) | |
| James M. Wilson | grad student | Penn (Cell & Gene Therapy Tree) |
Children
Sign in to add trainee| Livia Carvalho | post-doc | 2013-2015 | University of Perth, Australia (Cell & Gene Therapy Tree) |
| Nerea Zabaleta | post-doc | 2019-2022 | Harvard Medical School - Massachusetts Eye and Ear (Cell & Gene Therapy Tree) |
| Eric Zinn | research scientist | 2012-2015 | Harvard Medical School (Cell & Gene Therapy Tree) |
Collaborators
Sign in to add collaborator| Sadik H Kassim | collaborator | (Cell & Gene Therapy Tree) | |
| Casey A. Maguire | collaborator | The Massachusetts General Hospital (Cell & Gene Therapy Tree) |
BETA: Related publications
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Publications
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| Doshi J, Couto E, Staiti J, et al. (2024) E2A, VA RNA I, and L4-22k adenoviral helper genes are sufficient for AAV production in HEK293 cells. Molecular Therapy. Methods & Clinical Development. 32: 101376 |
| Bhatt U, Herate C, Estelien R, et al. (2024) Boost and Increased Antibody Breadth Following a Second Dose of PARVAX for SARS-CoV-2 in Mice and Nonhuman Primates. Vaccines. 12 |
| Kumar P, Wang M, Kumru OS, et al. (2023) Correlating physicochemical and biological properties to define critical quality attributes of a rAAV vaccine candidate. Molecular Therapy. Methods & Clinical Development. 30: 103-121 |
| Reichart D, Newby GA, Wakimoto H, et al. (2023) Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice. Nature Medicine |
| Hsu Y, Bhattarai S, Thompson JM, et al. (2022) Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model. Molecular Therapy. Nucleic Acids. 31: 164-181 |
| Florea M, Nicolaou F, Pacouret S, et al. (2022) High-efficiency purification of divergent AAV serotypes using AAVX affinity chromatography. Molecular Therapy. Methods & Clinical Development. 28: 146-159 |
| Zinn E, Unzu C, Schmit PF, et al. (2022) Ancestral library identifies conserved reprogrammable liver motif on AAV capsid. Cell Reports. Medicine. 100803 |
| Lu YC, Tsai YH, Chan YH, et al. (2022) Gene therapy with a synthetic adeno-associated viral vector improves audiovestibular phenotypes in Pjvk-mutant mice. Jci Insight. 7 |
| Zabaleta N, Bhatt U, Hérate C, et al. (2022) Durable immunogenicity, adaptation to emerging variants and low dose efficacy of AAV-based COVID19 platform in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Maciorowski D, Diop C, Bhatt U, et al. (2022) Immunogenicity of an AAV-Based COVID-19 Vaccine in Murine Models of Obesity and Aging. Viruses. 14 |