Huan Chen

Affiliations: 
2014 Columbia University, New York, NY 
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"Huan Chen"

Parents

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Lorraine S. Symington grad student 2014 Columbia (Chemistry Tree)
Frederick W. Alt post-doc Harvard
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Publications

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Wang Y, Wang M, Djekidel MN, et al. (2021) eccDNAs are apoptotic products with high innate immunostimulatory activity. Nature. 599: 308-314
Dai HQ, Hu H, Lou J, et al. (2021) Loop extrusion mediates physiological Igh locus contraction for RAG scanning. Nature
Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature
Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948
Chen H, Donnianni RA, Handa N, et al. (2015) Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: E1880-7
Deng SK, Chen H, Symington LS. (2015) Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 305-13
Bernstein KA, Mimitou EP, Mihalevic MJ, et al. (2013) Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae. Genetics. 195: 1241-51
Chen H, Lisby M, Symington LS. (2013) RPA coordinates DNA end resection and prevents formation of DNA hairpins. Molecular Cell. 50: 589-600
Chen H, Symington LS. (2013) Overcoming the chromatin barrier to end resection. Cell Research. 23: 317-9
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