Katharine A White
Affiliations: | University of California, San Francisco, San Francisco, CA |
Area:
pH dynamics, cancer cell behaviorsGoogle:
"Katharine White"Parents
Sign in to add mentor| Alice Y. Ting | grad student | 2007-2012 | MIT (Chemistry Tree) |
| Diane L. Barber | post-doc | 2012- | UCSF |
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Publications
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| Sesanto R, Kuehn JF, Barber DL, et al. (2021) Low pH Facilitates Heterodimerization of Mutant Isocitrate Dehydrogenase IDH1-R132H and Promotes Production of 2-Hydroxyglutarate. Biochemistry |
| Czowski BJ, Romero-Moreno R, Trull KJ, et al. (2020) Cancer and pH Dynamics: Transcriptional Regulation, Proteostasis, and the Need for New Molecular Tools. Cancers. 12 |
| Liu Y, White KA, Barber DL. (2020) Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective. Frontiers in Oncology. 10: 1401 |
| Luna LA, Lesecq Z, White KA, et al. (2020) An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity. The Biochemical Journal |
| White KA, Kisor K, Barber DL. (2019) Intracellular pH dynamics and charge-changing somatic mutations in cancer. Cancer Metastasis Reviews |
| Grillo-Hill BK, White KA. (2019) Oncogenic β-catenin mutations evade pH-regulated degradation. Molecular & Cellular Oncology. 6: 1554470 |
| White KA, Grillo-Hill BK, Esquivel M, et al. (2018) β-Catenin is a pH sensor with decreased stability at higher intracellular pH. The Journal of Cell Biology |
| Vercoulen Y, Kondo Y, Iwig JS, et al. (2017) A histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1. Elife. 6 |
| White KA, Ruiz DG, Szpiech ZA, et al. (2017) Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins. Science Signaling. 10 |
| Szpiech ZA, Strauli NB, White KA, et al. (2017) Prominent features of the amino acid mutation landscape in cancer. Plos One. 12: e0183273 |