Yuval Blat

Harvard University, Cambridge, MA, United States 
"Yuval Blat"
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Moslin R, Gardner D, Santella J, et al. (2017) Identification of imidazo[1,2-]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. Medchemcomm. 8: 700-712
Chupak LS, Zheng X, Hu S, et al. (2016) Structure activity relationship studies on chemically non-reactive glycine sulfonamide inhibitors of diacylglycerol lipase. Bioorganic & Medicinal Chemistry
Chaudhry C, Davis J, Zhang Y, et al. (2015) Building HTRF assays for characterization of bivalent inhibitors of an Inhibitor of Apoptosis Protein target. Analytical Biochemistry
Tokarski JS, Zupa-Fernandez A, Tredup JA, et al. (2015) Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. The Journal of Biological Chemistry. 290: 11061-74
Appiah KK, Blat Y, Robertson BJ, et al. (2014) Identification of small molecules that selectively inhibit diacylglycerol lipase-α activity. Journal of Biomolecular Screening. 19: 595-605
Blat Y. (2010) Non-competitive inhibition by active site binders. Chemical Biology & Drug Design. 75: 535-40
Fanslau C, Pedicord D, Nagulapalli S, et al. (2010) An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors. Analytical Biochemistry. 402: 65-8
Sahni-Arya B, Flynn MJ, Bergeron L, et al. (2007) Cofactor-specific modulation of 11beta-hydroxysteroid dehydrogenase 1 inhibitor potency. Biochimica Et Biophysica Acta. 1774: 1184-91
Blat Y, Protacio RU, Hunter N, et al. (2002) Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation. Cell. 111: 791-802
Blat Y, Meredith JE, Wang Q, et al. (2002) Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretase. Biochemical and Biophysical Research Communications. 299: 569-73
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