G Greg Wang
Affiliations: | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
stem cells, cancer, epigeneticsGoogle:
"G Greg Wang"Parents
Sign in to add mentor| Mark Kamps | grad student | (Neurotree) | |
| C. David Allis | post-doc | Rockefeller (PombeTree) |
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Publications
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| Corbin J, Yu X, Jin J, et al. (2024) EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth. Oncogene |
| Chen X, Guo Y, Zhao T, et al. (2024) Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction. Nature Communications. 15: 6217 |
| Lu J, Guo Y, Yin J, et al. (2024) Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. Nature Communications. 15: 3111 |
| Guo Y, Yu Y, Wang GG. (2023) Polycomb Repressive Complex 2 in Oncology. Cancer Treatment and Research. 190: 273-320 |
| Yu X, Li D, Kottur J, et al. (2023) Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer. Journal of Medicinal Chemistry |
| Zhao S, Lu J, Pan B, et al. (2023) TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature |
| Dardis GJ, Wang J, Simon JM, et al. (2023) An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer. Iscience. 26: 107115 |
| Xu C, Kim A, Corbin JM, et al. (2023) Onco-condensates: formation, multi-component organization, and biological functions. Trends in Cancer |
| Hanley RP, Nie DY, Tabor JR, et al. (2023) Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2. Journal of the American Chemical Society |
| Chi P, Lewis PW, Lu C, et al. (2023) Charles David Allis (1951-2023). Nature Genetics |