Michael J. Lukey

Molecular Medicine Cornell University, Ithaca, NY, United States 
"Michael Lukey"


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Fraser Armstrong grad student 2009-2013 Oxford (Telomere and Telomerase Tree)
Richard A. Cerione post-doc 2013- Cornell (Chemistry Tree)


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Ahmad A Cluntun collaborator 2015-2017 Cornell
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Lukey MJ, Greene KS, Cerione RA. (2020) Lysine succinylation and SIRT5 couple nutritional status to glutamine catabolism. Molecular & Cellular Oncology. 7: 1735284
Greene KS, Lukey MJ, Wang X, et al. (2019) SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America
Lukey MJ, Cluntun AA, Katt WP, et al. (2019) Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. Cell Reports. 29: 76-88.e7
Katt WP, Lukey MJ, Cerione RA. (2019) Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chemical Biology. 26: 1197-1199
Antonyak MA, Lukey MJ, Cerione RA. (2019) Lipid-filled vesicles modulate macrophages. Science (New York, N.Y.). 363: 931-932
Lukey MJ, Katt WP, Cerione RA. (2018) Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell. 33: 795-797
Cluntun AA, Lukey MJ, Cerione RA, et al. (2017) Glutamine Metabolism in Cancer: Understanding the Heterogeneity. Trends in Cancer. 3: 169-180
Katt WP, Lukey MJ, Cerione RA. (2017) A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis. Future Medicinal Chemistry
Lukey MJ, Katt WP, Cerione RA. (2016) Targeting amino acid metabolism for cancer therapy. Drug Discovery Today
Lukey MJ, Greene KS, Erickson JW, et al. (2016) The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nature Communications. 7: 11321
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