Shahid S. Siddiqui

University of Chicago Medical Center, Chicago, IL, United States 
Endothelial barrier function, C. elegans genetics, regenerative medicine, genome editing and oncology
"Shahid Siddiqui"


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Sydney Brenner grad student 1974- MRC-LMB (Neurotree)
 (Sydeny Brenner taught a course on developmental biology at TIFR in 1974 and introduced the C. elegans model system. Later I visited MRC Lab of Molecular Biology at Cambridge in 1976-1978 and interacted with C. elegans group at MRC)
Padmanabhan Babu grad student 1972-1978 TIFR, Mumbai
 (Dr. Babu introduced me to the genetics of C. elegans, and the use of fluorescent mutants.)
John E. Sulston grad student 1976-1978 MRC-LMB (Neurotree)
 (Dr. John Sulston guided me while I was working on genetic mosaics in C. elegans at TIFR in Bombay, and layer at Max-Planck Institute in Gottingen, Germany)
Gunter von Ehrenstein post-doc 1978-1981 Max-Planck-Institut für experimentelle Medizin
 (Prof. Gunter von Ehrenstein mentored me in graduate and post-doctoral years)


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Ravi Salgia collaborator 2007- Division of Biological Sciences, Pritzker School of Medicine
 (We have collaborated on the use of C. elegans to study human c-Met receptor kinase variants)
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Baleanu-Gogonea C, Siddiqui SS. (2020) Molecular cloning and three-dimensional structure prediction of a novel alpha-tubulin in Caenorhabditis elegans. Journal of Cellular and Molecular Medicine. 4: 183-195
Kanteti R, Dhanasingh I, El-Hashani E, et al. (2016) C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype. Cancer Biology & Therapy. 17: 91-103
Zhang J, Bakheet R, Parhar RS, et al. (2011) Regulation of fat storage and reproduction by Krüppel-like transcription factor KLF3 and fat-associated genes in Caenorhabditis elegans. Journal of Molecular Biology. 411: 537-53
Loganathan S, Kanteti R, Siddiqui SS, et al. (2011) Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism. Journal of Carcinogenesis. 10: 4
Siddiqui SS, Loganathan S, Krishnaswamy S, et al. (2008) C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes. Cancer Biology & Therapy. 7: 856-63
Siddiqui SS, Culotti JG. (2007) Examination of neurons in wild type and mutants of Caenorhabditis elegans using antibodies to horseradish peroxidase. Journal of Neurogenetics. 21: 271-89
Frey RS, Gao X, Javaid K, et al. (2006) Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells. The Journal of Biological Chemistry. 281: 16128-38
Yau DM, Yokoyama N, Goshima Y, et al. (2003) Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14748-53
Siddiqui SS. (2002) Metazoan motor models: kinesin superfamily in C. elegans. Traffic (Copenhagen, Denmark). 3: 20-8
Ali MY, Siddiqui ZK, Malik AB, et al. (2000) A novel C-terminal kinesin subfamily may be involved in chromosomal movement in caenorhabditis elegans. Febs Letters. 470: 70-6
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