Lawrence Kazak
Affiliations: | McGill University, Montreal, QC, Canada |
Area:
Mitochondria, thermogenesis, adipocyte biologyGoogle:
"Lawrence Kazak"Parents
Sign in to add mentor| Ian Holt | grad student | 2008-2013 | Cambridge (Mycotree) |
| Bruce Spiegelman | post-doc | 2013-2018 | Dana-Farber Cancer Institute and Harvard Medical School |
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Publications
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| Kazak L. (2023) Promoting metabolic inefficiency for metabolic disease. Iscience. 26: 107843 |
| Rahbani JF, Scholtes C, Lagarde DM, et al. (2022) ADRA1A-Gα signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism |
| Rahbani JF, Kazak L. (2022) A brown fat-selective mechanism of mitochondrial calcium import? Cell Metabolism. 34: 1231-1233 |
| Bertholet AM, Natale AM, Bisignano P, et al. (2022) Mitochondrial uncouplers induce proton leak by activating AAC and UCP1. Nature. 606: 180-187 |
| Rahbani JF, Chouchani ET, Spiegelman BM, et al. (2022) Measurement of Futile Creatine Cycling Using Respirometry. Methods in Molecular Biology (Clifton, N.J.). 2448: 141-153 |
| Sun Y, Rahbani JF, Jedrychowski MP, et al. (2021) Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine. Nature |
| Rahbani JF, Roesler A, Hussain MF, et al. (2021) Creatine kinase B controls futile creatine cycling in thermogenic fat. Nature. 590: 480-485 |
| Maguire OA, Ackerman SE, Szwed SK, et al. (2021) Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer. Cell Metabolism |
| Connell NJ, Doligkeit D, Andriessen C, et al. (2021) No evidence for brown adipose tissue activation after creatine supplementation in adult vegetarians. Nature Metabolism. 3: 107-117 |
| Kazak L, Spiegelman BM. (2020) Mechanism of futile creatine cycling in thermogenesis. American Journal of Physiology. Endocrinology and Metabolism |