Lawrence Kazak
Affiliations: | McGill University, Montreal, QC, Canada |
Area:
Mitochondria, thermogenesis, adipocyte biologyGoogle:
"Lawrence Kazak"Parents
Sign in to add mentor| Ian Holt | grad student | 2008-2013 | Cambridge (Mycotree) |
| Bruce Spiegelman | post-doc | 2013-2018 | Dana-Farber Cancer Institute and Harvard Medical School |
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Publications
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| Rahbani JF, Roesler A, Hussain MF, et al. (2021) Creatine kinase B controls futile creatine cycling in thermogenic fat. Nature. 590: 480-485 |
| Maguire OA, Ackerman SE, Szwed SK, et al. (2021) Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer. Cell Metabolism |
| Connell NJ, Doligkeit D, Andriessen C, et al. (2021) No evidence for brown adipose tissue activation after creatine supplementation in adult vegetarians. Nature Metabolism. 3: 107-117 |
| Kazak L, Cohen P. (2020) Creatine metabolism: energy homeostasis, immunity and cancer biology. Nature Reviews. Endocrinology |
| Jedrychowski MP, Lu GZ, Szpyt J, et al. (2020) Facultative protein selenation regulates redox sensitivity, adipose tissue thermogenesis, and obesity. Proceedings of the National Academy of Sciences of the United States of America |
| Bertholet AM, Chouchani ET, Kazak L, et al. (2019) H transport is an integral function of the mitochondrial ADP/ATP carrier. Nature. 571: 515-520 |
| Kazak L, Rahbani JF, Samborska B, et al. (2019) Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity. Nature Metabolism. 1: 360-370 |
| Dumesic PA, Egan DF, Gut P, et al. (2019) An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism |
| Chouchani ET, Kazak L, Spiegelman BM. (2018) New Advances in Adaptive Thermogenesis: UCP1 and Beyond. Cell Metabolism |
| Cluett TJ, Akman G, Reyes A, et al. (2018) Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication. Nucleic Acids Research |