Bingbing Wan, Ph.D

2014- Molecular Biology Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States 
DNA repair, telomere
"Bingbing Wan"


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Ming Lei post-doc 2014 University of Michigan (Telomere and Telomerase Tree)
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Wan B, Wu J, Meng X, et al. (2019) Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107. Molecular Cell. 75: 238-251.e5
Shultis D, Mitra P, Huang X, et al. (2019) Changing the Apoptosis Pathway through Evolutionary Protein Design. Journal of Molecular Biology
Wan B, Hang LE, Zhao X. (2016) Multi-BRCT scaffolds use distinct strategies to support genome maintenance. Cell Cycle (Georgetown, Tex.). 1-10
Bonner JN, Choi K, Xue X, et al. (2016) Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates. Cell Reports
Yin J, Wan B, Sarkar J, et al. (2016) Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex. Nucleic Acids Research
Wan B, Tang T, Upton H, et al. (2015) The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex. Nature Structural & Molecular Biology
Sarkar J, Wan B, Yin J, et al. (2015) SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates. Nucleic Acids Research
Sommers JA, Banerjee T, Hinds T, et al. (2014) Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner. The Journal of Biological Chemistry. 289: 19928-41
Yang YW, Flynn RA, Chen Y, et al. (2014) Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. Elife. 3: e02046
Wan B, Yin J, Horvath K, et al. (2013) SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres. Cell Reports. 4: 861-9
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