Alison K. Holzer, Ph.D.
Affiliations: | 2006 | University of California, San Diego, La Jolla, CA |
Area:
Cell BiologyGoogle:
"Alison Holzer"Parents
Sign in to add mentor| Stephen B. Howell | grad student | 2006 | UCSD | |
| (The regulation of the human copper transporter 1 and its role in the cellular uptake of cisplatin.) | ||||
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Publications
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| Holzer AK, Howell SB. (2006) The internalization and degradation of human copper transporter 1 following cisplatin exposure. Cancer Research. 66: 10944-52 |
| Holzer AK, Manorek GH, Howell SB. (2006) Contribution of the major copper influx transporter CTR1 to the cellular accumulation of cisplatin, carboplatin, and oxaliplatin. Molecular Pharmacology. 70: 1390-4 |
| Holzer AK, Varki NM, Le QT, et al. (2006) Expression of the human copper influx transporter 1 in normal and malignant human tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 1041-9 |
| Safaei R, Katano K, Larson BJ, et al. (2005) Intracellular localization and trafficking of fluorescein-labeled cisplatin in human ovarian carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 756-67 |
| Holzer AK, Katano K, Klomp LW, et al. (2004) Cisplatin rapidly down-regulates its own influx transporter hCTR1 in cultured human ovarian carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 6744-9 |
| Safaei R, Holzer AK, Katano K, et al. (2004) The role of copper transporters in the development of resistance to Pt drugs. Journal of Inorganic Biochemistry. 98: 1607-13 |
| Samimi G, Safaei R, Katano K, et al. (2004) Increased expression of the copper efflux transporter ATP7A mediates resistance to cisplatin, carboplatin, and oxaliplatin in ovarian cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4661-9 |
| Katano K, Safaei R, Samimi G, et al. (2004) Confocal microscopic analysis of the interaction between cisplatin and the copper transporter ATP7B in human ovarian carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 4578-88 |
| Holzer AK, Samimi G, Katano K, et al. (2004) The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells. Molecular Pharmacology. 66: 817-23 |
| Samimi G, Katano K, Holzer AK, et al. (2004) Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B. Molecular Pharmacology. 66: 25-32 |