Margaret A. Goodell

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Hong T, Li J, Guo L, et al. (2023) TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells. Nature Aging
Chen CW, Zhang L, Dutta R, et al. (2023) SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation. Cell Stem Cell
Liu L, Kim S, Buckley MT, et al. (2023) Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging. Cell Stem Cell
Ramabadran R, Wang JH, Reyes JM, et al. (2023) DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nature Cell Biology
Brunet A, Goodell MA, Rando TA. (2022) Ageing and rejuvenation of tissue stem cells and their niches. Nature Reviews. Molecular Cell Biology
Tovy A, Rosas C, Gaikwad AS, et al. (2021) Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome. Haematologica
Challen G, Goodell MA. (2020) Clonal Hematopoiesis: Mechanisms Driving Dominance of Stem Cell Clones. Blood
Tovy A, Reyes JM, Gundry MC, et al. (2020) Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion. Cell Stem Cell
Datar GK, Goodell MA. (2020) Where There's Smoke, There's Fire: Inflammation Drives MDS. Trends in Immunology. 41: 558-560
Zhang X, Jeong M, Huang X, et al. (2020) Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Molecular Cell. 78: 506-521.e6