Philipp F Lange

Affiliations: 
University of British Columbia (UBC) 
Area:
Cancer, Proteomics, Childhood Cancer, Rare Disease, Precision Medicine, Post translational protein modification, Proteoforms, Mass Spectrometry
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"Philipp Lange"
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Publications

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Weng SS, Demir F, Ergin EK, et al. (2019) Sensitive determination of proteolytic proteoforms in limited microscale proteome samples. Molecular & Cellular Proteomics : McP
Prudova A, Gocheva V, Auf dem Keller U, et al. (2016) TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports
Eckhard U, Huesgen PF, Schilling O, et al. (2016) Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14. Data in Brief. 7: 299-310
Eckhard U, Huesgen PF, Schilling O, et al. (2015) Active site specificity of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses. Matrix Biology : Journal of the International Society For Matrix Biology
Huesgen PF, Lange PF, Rogers LD, et al. (2015) LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification Nature Methods. 12: 55-58
Fortelny N, Yang S, Pavlidis P, et al. (2015) Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events. Nucleic Acids Research. 43: D290-7
Bellac CL, Dufour A, Krisinger MJ, et al. (2014) Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis. Cell Reports. 9: 618-32
Fortelny N, Cox JH, Kappelhoff R, et al. (2014) Network analyses reveal pervasive functional regulation between proteases in the human protease web. Plos Biology. 12: e1001869
Lange PF, Huesgen PF, Nguyen K, et al. (2014) Annotating N termini for the human proteome project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human erythrocyte proteome. Journal of Proteome Research. 13: 2028-44
Huesgen PF, Lange PF, Overall CM. (2014) Ensembles of protein termini and specific proteolytic signatures as candidate biomarkers of disease. Proteomics. Clinical Applications. 8: 338-50
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