Andre Nussenzweig, Ph.D.

Center for Cancer Research National Cancer Institute, NIH, Bethesda, Bethesda, MD, United States 
genomic Instability, DNA damage/repair, recombination/replication
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Paiano J, Zolnerowich N, Wu W, et al. (2021) Role of 53BP1 in end protection and DNA synthesis at DNA breaks. Genes & Development
Chen BR, Wang Y, Tubbs A, et al. (2021) LIN37-DREAM prevents DNA end resection and homologous recombination at DNA double-strand breaks in quiescent cells. Elife. 10
Olbrich T, Vega-Sendino M, Tillo D, et al. (2021) CTCF is a barrier for 2C-like reprogramming. Nature Communications. 12: 4856
van Wietmarschen N, Nathan WJ, Nussenzweig A. (2021) The WRN helicase: resolving a new target in microsatellite unstable cancers. Current Opinion in Genetics & Development. 71: 34-38
Mei Q, Fitzgerald DM, Liu J, et al. (2021) Two mechanisms of chromosome fragility at replication-termination sites in bacteria. Science Advances. 7
Zatreanu D, Robinson HMR, Alkhatib O, et al. (2021) Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nature Communications. 12: 3636
Ramsden DA, Nussenzweig A. (2021) Mechanisms driving chromosomal translocations: lost in time and space. Oncogene. 40: 4263-4270
Shinoda K, Zong D, Callen E, et al. (2021) The dystonia gene THAP1 controls DNA double-strand break repair choice. Molecular Cell
Wu W, Hill SE, Nathan WJ, et al. (2021) Neuronal enhancers are hotspots for DNA single-strand break repair. Nature
Feldhahn N, Ferretti E, Robbiani DF, et al. (2021) The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. The Embo Journal. 40: e107130
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