Andre Nussenzweig, Ph.D.

Center for Cancer Research National Cancer Institute, NIH, Bethesda, Bethesda, MD, United States 
genomic Instability, DNA damage/repair, recombination/replication
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Callen E, Zong D, Wu W, et al. (2019) 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. Molecular Cell
Canela A, Maman Y, Huang SN, et al. (2019) Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity. Molecular Cell
Zong D, Adam S, Wang Y, et al. (2019) BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation. Molecular Cell
Tubbs A, Sridharan S, van Wietmarschen N, et al. (2018) Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse. Cell
Di Siena S, Campolo F, Gimmelli R, et al. (2018) Atm reactivation reverses ataxia telangiectasia phenotypes in vivo. Cell Death & Disease. 9: 314
Canela A, Maman Y, Jung S, et al. (2017) Genome Organization Drives Chromosome Fragility. Cell
Chaudhuri AR, Callen E, Ding X, et al. (2016) Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature
Li M, Cole F, Patel DS, et al. (2016) 53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1. Embo Reports
Morgado-Palacin I, Day A, Murga M, et al. (2016) Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML. Science Signaling. 9: ra91
Nieto-Soler M, Morgado-Palacin I, Lafarga V, et al. (2016) Efficacy of ATR inhibitors as single agents in Ewing sarcoma. Oncotarget. 7: 58759-58767
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