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Nikola P. Pavletich

Affiliations: 
Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
Area:
Cancer Biology, Structural Biology
Website:
http://www.hhmi.org/scientists/nikola-p-pavletich
Google:
"Nikola P. Pavletich"
Bio:

http://www.nasonline.org/member-directory/members/20027263.html
http://www.mskcc.org/research/lab/nikola-pavletich

Mean distance: 8.29
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Parents

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Carl O. Pabo grad student 1991 Johns Hopkins Medical School
 (Crystal structure of a zinc finger/DNA complex : a framework for understanding how zinc fingers recognize DNA)
Carl O. Pabo post-doc MIT

Children

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research assistant 2002-2005 (Neurotree)
Nicolas H. Thomä grad student
Zhucheng Chen grad student 2003-2008 Memorial Sloan-Kettering Cancer Center
Jung-Hyun Min post-doc Memorial Sloan-Kettering Cancer Center
Seth M. Rubin post-doc Memorial Sloan-Kettering Cancer Center
Ning Zheng post-doc 1997- Memorial Sloan-Kettering Cancer Center
Yigong Shi post-doc 1996-1997 Memorial Sloan-Kettering Cancer Center
Brenda A. Schulman post-doc 1998-2001 Memorial Sloan Kettering Cancer Center (Cell Biology Tree)

Collaborators

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Publications

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Warren C, Pavletich NP. (2022) Structure of the human ATM kinase and mechanism of Nbs1 binding. Elife. 11
Yang H, Pavletich NP. (2021) Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates. Current Opinion in Genetics & Development. 71: 188-194
Wang S, Wang R, Peralta C, et al. (2021) Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. Nature Structural & Molecular Biology
Yang H, Zhou C, Dhar A, et al. (2020) Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures. Nature
Wang R, Wang S, Dhar A, et al. (2020) DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex. Nature. 580: 278-282
Wojnarowicz PM, Lima E Silva R, Ohnaka M, et al. (2019) A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Reports. 29: 62-75.e7
Yang H, Jiang X, Li B, et al. (2017) Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. Nature
Wojnarowicz PM, Desai B, Chin Y, et al. (2017) Abstract 4975: A small molecule pan Id protein antagonist shows strong antitumor activity Cancer Research. 77: 4975-4975
Chang E, Pourmal S, Zhou C, et al. (2016) N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis. Journal of Biomolecular Techniques : Jbt
Zhou C, Pourmal S, Pavletich NP. (2015) Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife. 4
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