Michael Ned Margolies, M.D.
Affiliations: | Surgery | Massachusetts General Hospital, Boston, MA |
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"Michael Ned Margolies, M.D."
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| Krykbaev RA, Tsantili P, Jeffrey PD, et al. (2002) Modifying specificity of antidigoxin antibodies using insertional mutagenesis. Protein Science : a Publication of the Protein Society. 11: 2899-908 |
| Parhami-Seren B, Haberly R, Margolies MN, et al. (2002) Ouabain-binding protein(s) from human plasma. Hypertension (Dallas, Tex. : 1979). 40: 220-8 |
| Short MK, Krykbaev RA, Jeffrey PD, et al. (2002) Complementary combining site contact residue mutations of the anti-digoxin Fab 26-10 permit high affinity wild-type binding. The Journal of Biological Chemistry. 277: 16365-70 |
| Parhami-Seren B, Viswanathan M, Margolies MN. (2002) Selection of high affinity p-azophenyarsonate Fabs from heavy-chain CDR2 insertion libraries. Journal of Immunological Methods. 259: 43-53 |
| Parhami-Seren B, Viswanathan M, Strong RK, et al. (2001) Structural analysis of mutants of high-affinity and low-affinity p-azophenylarsonate-specific antibodies generated by alanine scanning of heavy chain complementarity-determining region 2 Journal of Immunology. 167: 5129-5135 |
| Short MK, Jeffrey PD, Demirjian A, et al. (2001) A single H:CDR3 residue in the anti-digoxin antibody 26-10 modulates specificity for C16-substituted digoxin analogs. Protein Engineering. 14: 287-96 |
| Krykbaev RA, Liu WR, Jeffrey PD, et al. (2001) Phage display-selected sequences of the heavy-chain CDR3 loop of the anti-digoxin antibody 26-10 define a high affinity binding site for position 16-substituted analogs of digoxin. The Journal of Biological Chemistry. 276: 8149-58 |
| Ball WJ, Wang Z, Malik B, et al. (2000) Selection of peptidic mimics of digoxin from phage-displayed peptide libraries by anti-digoxin antibodies. Journal of Molecular Biology. 301: 101-15 |
| Roy P, Roth CM, Margolies MN, et al. (2000) Aromatic residues mediate the pressure-induced association of digoxigenin and antibody 26-10 Biophysical Chemistry. 83: 171-177 |
| Kim SH, Titlow CC, Margolies MN. (2000) An approach for preventing recombination-deletion of the 40-50 anti-digoxin antibody V(H) gene from the phage display vector pComb3. Gene. 241: 19-25 |