Hiroyuki Hosokawa

Affiliations: 
2018 California Institute of Technology, Pasadena, CA 
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"Hiroyuki Hosokawa"
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Hirano KI, Hosokawa H, Koizumi M, et al. (2021) LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. Elife. 10
Hosokawa H, Koizumi M, Masuhara K, et al. (2021) Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro-T cells. The Journal of Experimental Medicine. 218
Yazawa M, Hosokawa H, Koizumi M, et al. (2021) Notch signaling supports the appearance of follicular helper T cells in the Peyer's patches concomitantly with the reduction of regulatory T cells. International Immunology
Shin B, Hosokawa H, Romero-Wolf M, et al. (2021) Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching. Proceedings of the National Academy of Sciences of the United States of America. 118
Masuhara K, Akatsuka H, Tokusanai M, et al. (2020) AMBRA1 controls antigen-driven activation and proliferation of naïve T cells. International Immunology
Romero-Wolf M, Shin B, Zhou W, et al. (2020) Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development. The Journal of Cell Biology. 219
Hosokawa H, Romero-Wolf M, Yang Q, et al. (2019) Cell type-specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells. The Journal of Experimental Medicine
Marshansky V, Hosokawa H, Merkulova M, et al. (2019) Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design. Current Topics in Membranes. 83: 77-106
Rothenberg EV, Hosokawa H, Ungerbäck J. (2019) Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development. Frontiers in Immunology. 10: 228
Hosokawa H, Romero-Wolf M, Yui MA, et al. (2018) Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16. Nature Immunology. 19: 1427-1440
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