Christine Kinnon

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1987 California Institute of Technology, Pasadena, CA 
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"Christine Kinnon"
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Vetrie D, Vo?echovský I, Sideras P, et al. (2012) The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993. Journal of Immunology (Baltimore, Md. : 1950). 188: 2948-55
Gaspar HB, Cooray S, Gilmour KC, et al. (2011) Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction. Science Translational Medicine. 3: 97ra80
Gaspar HB, Cooray S, Gilmour KC, et al. (2011) Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency. Science Translational Medicine. 3: 97ra79
Abeyewickreme A, Thrasher AJ, Kinnon C. (2011) Bone morphogenetic protein-4 (BMP4) up regulates key haematopoietic genes in differentiating embryonic stem cells treated with BMP4 short hairpin RNA British Journal of Haematology. 155: 638-641
Ward NJ, Buckley SM, Waddington SN, et al. (2011) Codon optimization of human factor VIII cDNAs leads to high-level expression. Blood. 117: 798-807
Blundell MP, Bouma G, Metelo J, et al. (2009) Phosphorylation of WASp is a key regulator of activity and stability in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 15738-43
Howe SJ, Mansour MR, Schwarzwaelder K, et al. (2008) Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients Journal of Clinical Investigation. 118: 3143-3150
Blundell MP, Bouma G, Calle Y, et al. (2008) Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy Molecular Therapy. 16: 836-844
Santilli G, Thornhill SI, Kinnon C, et al. (2008) Gene therapy of inherited immunodeficiencies Expert Opinion On Biological Therapy. 8: 397-407
Moulding DA, Blundell MP, Spiller DG, et al. (2007) Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia. The Journal of Experimental Medicine. 204: 2213-24
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