Phillip Allen Sharp
Affiliations: | Biology | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
Gene splicingWebsite:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1993/sharp-bio.htmlGoogle:
"Phillip Sharp"Bio:
https://biology.mit.edu/people/phillip_sharp
http://web.mit.edu/sharplab/index.html
http://www.chemheritage.org/discover/collections/oral-histories/details/sharp-phillip-a.aspx
http://www.nasonline.org/member-directory/members/50570.html
The Nobel Prize in Physiology or Medicine 1993 was awarded jointly to Richard J. Roberts and Phillip A. Sharp for their discoveries of split genes
Cross-listing: Chemistry Tree - DevTree
Parents
Sign in to add mentor| Victor A. Bloomfield | grad student | 1969 | UIUC (Chemistry Tree) | |
| (Physical chemistry of deoxyribonucleic acids and virus) | ||||
| Norman Davidson | post-doc | Caltech (Neurotree) | ||
| James D. Watson | post-doc | CSHL (Chemistry Tree) | ||
Children
Sign in to add trainee| Steve Buratowski | grad student | MIT (PombeTree) | |
| Stephen Buratowski | grad student | (Chemistry Tree) | |
| Constance L. Cepko | grad student | MIT (Neurotree) | |
| John D. Crispino | grad student | (Chemistry Tree) | |
| Daniel J. Donoghue | grad student | 1979 | MIT (Chemistry Tree) |
| Ihor R. Lemischka | grad student | 1977-1982 | MIT |
| Andrew Zachary Fire | grad student | 1983 | MIT (Chemistry Tree) |
| Benjamin M. Shykind | grad student | 1988-1996 | MIT (Neurotree) |
| Xuebing Wu | grad student | 2010-2014 | MIT (Computational Biology Tree) |
| Courtney JnBaptiste | grad student | 2011-2016 | MIT (Chemistry Tree) |
| Arnold J. Berk | post-doc | (Microtree) | |
| Derek Dykxhoorn | post-doc | MIT (GenetiTree) | |
| Cathie Garnis | post-doc | MIT (FlyTree) | |
| Hiroshi Handa | post-doc | MIT | |
| Randal J. Kaufman | post-doc | MIT (Chemistry Tree) | |
| Jae Bum Kim | post-doc | (Chemistry Tree) | |
| Maria Magda Konarska | post-doc | MIT (Chemistry Tree) | |
| Angus Lamond | post-doc | MIT | |
| Andrew MacMilan | post-doc | MIT (Chemistry Tree) | |
| Melissa J. Moore | post-doc | MIT | |
| Richard Mulligan | post-doc | MIT | |
| Barbara Panning | post-doc | ||
| Amy C. Seila | post-doc | MIT (Chemistry Tree) | |
| Thomas Tuschl | post-doc | Whitehead Institute (MIT) (Computational Biology Tree) | |
| Robert E. Kingston | post-doc | 1985 | MIT (Chemistry Tree) |
| Richard A. Padgett | post-doc | 1981-1985 | MIT (Chemistry Tree) |
| John M. Sedivy | post-doc | 1984-1988 | MIT |
| Harinder Singh | post-doc | 1984-1988 | MIT |
| Myles Brown | post-doc | 1987-1990 | |
| Jørgen Kjems | post-doc | 1990-1992 | MIT (Chemistry Tree) |
| Benjamin Blencowe | post-doc | 1992-1998 | MIT |
| Christopher B. Burge | post-doc | 1997-1999 | MIT (Computational Biology Tree) |
| Michael Thomas McManus | post-doc | 2000-2004 | MIT (Chemistry Tree) |
| Anthony K. L. Leung | post-doc | 2004-2011 | MIT (Chemistry Tree) |
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Publications
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| Chakraborty M, Hu S, Visness E, et al. (2020) MicroRNAs organize intrinsic variation into stem cell states. Proceedings of the National Academy of Sciences of the United States of America |
| Whipple AJ, Breton-Provencher V, Jacobs HN, et al. (2020) Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons. Molecular Cell |
| Shrinivas K, Sabari BR, Coffey EL, et al. (2019) Enhancer Features that Drive Formation of Transcriptional Condensates. Molecular Cell. 75: 549-561.e7 |
| Guo YE, Manteiga JC, Henninger JE, et al. (2019) Pol II phosphorylation regulates a switch between transcriptional and splicing condensates. Nature |
| Grigelioniene G, Suzuki HI, Taylan F, et al. (2019) Gain-of-function mutation of microRNA-140 in human skeletal dysplasia. Nature Medicine |
| Dubbury SJ, Boutz PL, Sharp PA. (2018) CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 564: 141-145 |
| Sabari BR, Dall'Agnese A, Boija A, et al. (2018) Coactivator condensation at super-enhancers links phase separation and gene control. Science (New York, N.Y.) |
| Suzuki HI, Spengler RM, Grigelioniene G, et al. (2018) Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics. Nature Genetics |
| Chiu AC, Suzuki HI, Wu X, et al. (2018) Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP. Molecular Cell |
| Murphy PA, Butty VL, Boutz PL, et al. (2018) Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow. Elife. 7 |