Tobias c Walther
Affiliations: | Harvard Medical School, Boston, MA, United States |
Area:
Metabolism, Cell Biology, Membranes, Organelles, Lipids,Google:
"Tobias Walther"Parents
Sign in to add mentor| Iain Mattaj | grad student | 1999-2003 | EMBL Heidelberg (Neurotree) |
| Peter Walter | post-doc | 2003-2006 | UCSF |
Children
Sign in to add trainee| FLorian Froehlich | grad student | Harvard | |
| Nora Kory | grad student | Harvard School of Public Health | |
| Natalie Krahmer | grad student | German Diabetes Center | |
| Florian Wilfling | grad student | Max Planck Insitute | |
| Niklas Mejhert | post-doc | Harvard | |
| Andrew Nguyen | post-doc | University of St Louis | |
| Abdou Rachid Thiam | post-doc | Harvard |
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Publications
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| Chitraju C, Fischer AW, Ambaw YA, et al. (2023) Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity. Elife. 12 |
| Chung J, Park J, Lai ZW, et al. (2023) The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets. Nature Cell Biology |
| Wang K, Lee CW, Sui X, et al. (2023) The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification. Nature Communications. 14: 3533 |
| Sui X, Wang K, Song K, et al. (2023) Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis. Nature Communications. 14: 3100 |
| Walther TC, Kim S, Arlt H, et al. (2023) Structure and function of lipid droplet assembly complexes. Current Opinion in Structural Biology. 80: 102606 |
| Bond LM, Ibrahim A, Lai ZW, et al. (2023) Fitm2 is required for ER homeostasis and normal function of murine liver. The Journal of Biological Chemistry. 103022 |
| Boland S, Swarup S, Ambaw YA, et al. (2022) Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis. Nature Communications. 13: 5924 |
| Farese RV, Walther TC. (2022) Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum. Cold Spring Harbor Perspectives in Biology |
| Song J, Mizrak A, Lee CW, et al. (2022) Identification of two pathways mediating protein targeting from ER to lipid droplets. Nature Cell Biology |
| Kim S, Chung J, Arlt H, et al. (2022) Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane. Elife. 11 |