Lawrence B. Dumas

1970-2007 Biological Science Northwestern University, Evanston, IL 
viral DNA replication
"Lawrence Bernard Dumas" OR "Lawrence B. Dumas"

(1941 - 2008)


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Paul J. Kaesberg grad student 1968 UW Madison (Chemistry Tree)
 (RNA bacteriophage induced RNA polymerases: purification and reaction properties)
Robert L. Sinsheimer post-doc 1968-1970 Caltech (Chemistry Tree)


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Harinder Singh grad student 1979-1984 Northwestern
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Solomon NA, Wright MB, Chang S, et al. (1992) Genetic and molecular analysis of DNA43 and DNA52: two new cell-cycle genes in Saccharomyces cerevisiae. Yeast (Chichester, England). 8: 273-89
Brooke RG, Dumas LB. (1991) Reconstitution of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex in vitro. The 86-kDa subunit facilitates but is not required for complex formation Journal of Biological Chemistry. 266: 10093-10098
Brooke RG, Singhal R, Hinkle DC, et al. (1991) Purification and characterization of the 180- and 86-kilodalton subunits of the Saccharomyces cerevisiae DNA primase-DNA polymerase protein complex: The 180-kilodalton subunit has both DNA polymerase and 3' → 5'-exonuclease activities Journal of Biological Chemistry. 266: 3005-3015
Brooks M, Dumas LB. (1989) DNA primase isolated from the yeast DNA primase-DNA polymerase complex. Immunoaffinity purification and analysis of RNA primer synthesis. The Journal of Biological Chemistry. 264: 3602-10
Singh H, Brooke RG, Pausch MH, et al. (1986) Yeast DNA primase and DNA polymerase activities. An analysis of RNA priming and its coupling to DNA synthesis. The Journal of Biological Chemistry. 261: 8564-9
Singh H, Dumas LB. (1984) A DNA primase that copurifies with the major DNA polymerase from the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 259: 7936-40
Singh H, Bieker JJ, Dumas LB. (1982) Genetic transformation of Saccharomyces cerevisiae with single-stranded circular DNA vectors. Gene. 20: 441-9
Bieker JJ, Dumas LB. (1981) The single-strands of yeast autonomously replicating DNA segments are not recognized as origins of replication by Escherichia coli DNA replication proteins Biochemical and Biophysical Research Communications. 101: 194-200
Bieker JJ, Dumas LB. (1980) An easy, quantitative method for detection of endonuclease activity Analytical Biochemistry. 108: 285-289
Bayne ML, Dumas LB. (1979) Initiation of DNA synthesis on the isolated strands of bacteriophage f1 replicative-form DNA. Journal of Virology. 29: 1014-22
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