Harinder Singh

Affiliations: 
1989-2009 University of Chicago, Chicago, IL 
 2019- University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Immunology
Website:
https://alleninstitute.org/about/advisors/advisor-profiles/harinder-singh/
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"Harinder Singh"

Parents

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Lawrence B. Dumas grad student 1979-1984 Northwestern
 (Molecular analysis of initiation of DNA synthesis in the yeast Saccharomyces cerevisiae)
David Baltimore post-doc 1984-1988 MIT
Phillip Allen Sharp post-doc 1984-1988 MIT

Children

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Christopher A. Klug grad student 1993 Chicago (Microtree)
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Publications

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Yuan Kueh H, Handel A, Hoffmann A, et al. (2024) What unique insights can modeling approaches capture about the immune system? Cell Systems. 15: 1148-1152
Manakkat Vijay GK, Zhou M, Thakkar K, et al. (2024) Temporal dynamics and genomic programming of plasma cell fates. Nature Immunology
Cillo AR, Somasundaram A, Shan F, et al. (2021) Critically ill COVID-19 patients exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 viral burden in the lung. Cell Reports. Medicine. 100476
Ma X, Somasundaram A, Qi Z, et al. (2021) SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators. Nucleic Acids Research
Louis K, Bailly E, Macedo C, et al. (2021) T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants. Jci Insight
Chen D, Wang Y, Manakkat Vijay GK, et al. (2021) Coupled analysis of transcriptome and BCR mutations reveals role of OXPHOS in affinity maturation. Nature Immunology
Reiman D, Manakkat Vijay GK, Xu H, et al. (2021) Pseudocell Tracer-A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination. Plos Computational Biology. 17: e1008094
Cillo AR, Somasundaram A, Shan F, et al. (2021) Bifurcated monocyte states are predictive of mortality in severe COVID-19. Biorxiv : the Preprint Server For Biology
Almanan M, Raynor J, Ogunsulire I, et al. (2020) IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression. Science Advances. 6: eabb0806
Antoniou K, Ender F, Vollbrandt T, et al. (2020) Allergen-Induced C5a/C5aR1 Axis Activation in Pulmonary CD11b cDCs Promotes Pulmonary Tolerance through Downregulation of CD40. Cells. 9
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