William Holmes

Brown University, Providence, RI 
"William Holmes"
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Griffith AA, Holmes W. (2019) Fine Tuning: Effects of Post-Translational Modification on Hsp70 Chaperones. International Journal of Molecular Sciences. 20
Griffith AA, Boutin J, Holmes W. (2018) A highly efficient, one-step purification of the Hsp70 chaperone Ssa1. Protein Expression and Purification. 152: 56-63
Thompson AC, Bruss MD, Price JC, et al. (2015) Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice. Aging Cell
Holmes WM, Mannakee BK, Gutenkunst RN, et al. (2014) Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding. Nature Communications. 5: 4383
Holmes WM, Klaips CL, Serio TR. (2014) Defining the limits: Protein aggregation and toxicity in vivo Critical Reviews in Biochemistry and Molecular Biology. 49: 294-303
Decaris ML, Gatmaitan M, FlorCruz S, et al. (2014) Proteomic analysis of altered extracellular matrix turnover in bleomycin-induced pulmonary fibrosis. Molecular & Cellular Proteomics : McP. 13: 1741-52
Price JC, Khambatta CF, Li KW, et al. (2012) The effect of long term calorie restriction on in vivo hepatic proteostatis: a novel combination of dynamic and quantitative proteomics. Molecular & Cellular Proteomics : McP. 11: 1801-14
Bawa Z, Bland CE, Bonander N, et al. (2011) Understanding the yeast host cell response to recombinant membrane protein production. Biochemical Society Transactions. 39: 719-23
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