Anthony J. Muslin

Tectonic Therapeutic 
Signal transduction
"Anthony Muslin"
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Bergougnan L, Andersen G, Plum-Mörschel L, et al. (2020) Endothelial-protective effects of a G-protein-biased S1P agonist, SAR247799, in type-2 diabetes rats and a randomized placebo-controlled patient trial. British Journal of Clinical Pharmacology
Bergougnan L, Armani S, Golor G, et al. (2020) First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased Sphingosine-1 phosphate receptor-1 agonist for endothelial protection. British Journal of Clinical Pharmacology
Poirier B, Briand V, Kadereit D, et al. (2020) A G protein-biased S1P agonist, SAR247799, protects endothelial cells without affecting lymphocyte numbers. Science Signaling. 13
Beauverger P, Ozoux ML, Bégis G, et al. (2019) Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy. Cardiovascular Research
Villard EF, Thedrez A, Blankenstein J, et al. (2016) PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo: An Effect Blunted by Alirocumab. Jacc. Basic to Translational Science. 1: 419-427
Pang P, Jin X, Proctor BM, et al. (2015) RGS4 inhibits angiotensin II signaling and macrophage localization during renal reperfusion injury independent of vasospasm. Kidney International. 87: 771-83
Williams JW, Yau D, Sethakorn N, et al. (2013) RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L693-701
Beharier O, Dror S, Levy S, et al. (2012) ZnT-1 protects HL-1 cells from simulated ischemia-reperfusion through activation of Ras-ERK signaling. Journal of Molecular Medicine (Berlin, Germany). 90: 127-38
Sari FR, Widyantoro B, Thandavarayan RA, et al. (2011) Attenuation of CHOP-mediated myocardial apoptosis in pressure-overloaded dominant negative p38α mitogen-activated protein kinase mice. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 27: 487-96
Siedlecki AM, Jin X, Thomas W, et al. (2011) RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury. Kidney International. 80: 263-71
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