David M. Langenau
Affiliations: | Molecular Pathology | Massachusetts General Hospital & Harvard Medical School, Boston, MA, United States |
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Publications
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Prajapati K, Yan C, Yang Q, et al. (2024) The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies. Science Advances. 10: eadj4698 |
Cardoso BA, Duque M, Gírio A, et al. (2023) CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia. Haematologica |
Wei Y, Qin Q, Yan C, et al. (2022) Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma. Nature Cancer |
Oliveira ML, Veloso A, Garcia EG, et al. (2022) Mutant IL7R collaborates with MYC to induce T-cell acute lymphoblastic leukemia. Leukemia. 36: 1533-1540 |
Laukkanen S, Bacquelaine Veloso A, Yan C, et al. (2022) Combination therapies to inhibit LCK tyrosine kinase and mTOR signaling in T-cell Acute Lymphoblastic Leukemia. Blood |
Zhang S, Yan C, Millar DG, et al. (2021) Antibody-peptide epitope conjugates for personalized cancer therapy. Cancer Research |
Yan C, Yang Q, Zhang S, et al. (2021) Single-cell imaging of T cell immunotherapy responses in vivo. The Journal of Experimental Medicine. 218 |
Loontiens S, Dolens AC, Strubbe S, et al. (2020) PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation. Frontiers in Cell and Developmental Biology. 8: 599472 |
Yan C, Do D, Yang Q, et al. (2020) Single-cell imaging of human cancer xenografts using adult immunodeficient zebrafish. Nature Protocols |
Garcia EG, Veloso A, Oliveira ML, et al. (2020) PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia |