Colin R. Jefcoate, D. Phil.
Affiliations: | Pharmacology | University of Wisconsin, Madison, Madison, WI |
Area:
Cytochromes P450, xenobiotic metabolism, steroidogenesisGoogle:
"Colin Jefcoate"Mean distance: 8.62 | S | N | B | C | P |
Parents
Sign in to add mentor| Richard O. C. Norman | grad student | 1964-1966 | Oxford University, York University |
| James L Gaylor | post-doc | 1967-1969 | Cornell |
Children
Sign in to add trainee| Israel Hanukoglu | grad student | 1977-1980 | UW Madison |
| Young C. Cho | grad student | 2003 | UW Madison |
| Paul Robert Hanlon | grad student | 2003 | UW Madison |
| Noe Galvan | grad student | 2004 | UW Madison |
| Melissa Antonio Cimafranca | grad student | 2006 | UW Madison |
| Haichuan Duan | grad student | 2007 | UW Madison |
| Justin Bushkofsky | grad student | 2012 | UW Madison |
| Jinwoo Lee | grad student | 2012 | UW Madison |
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Publications
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| Kothandapani A, Larsen MC, Lee J, et al. (2021) Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium. Molecular and Cellular Endocrinology. 111265 |
| Larsen MC, Lee J, Jorgensen JS, et al. (2020) STARD1 Functions in Mitochondrial Cholesterol Metabolism and Nascent HDL Formation. Gene Expression and Molecular mRNA Imaging Show Novel Splicing and a 1:1 Mitochondrial Association. Frontiers in Endocrinology. 11: 559674 |
| Larsen MC, Almeldin A, Tong T, et al. (2020) Cytochrome P4501B1 in bone marrow is co-expressed with key markers of mesenchymal stem cells. BMS2 cell line models PAH disruption of bone marrow niche development functions. Toxicology and Applied Pharmacology. 115111 |
| Maguire M, Larsen MC, Vezina CM, et al. (2020) Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development. Plos One. 15: e0228436 |
| Day JH, Nicholson TM, Su X, et al. (2019) Injection molded open microfluidic well plate inserts for user-friendly coculture and microscopy. Lab On a Chip |
| Ostrem Loss EM, Lee MK, Wu MY, et al. (2019) Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[]Pyrene by Species. Mbio. 10 |
| Jefcoate CR, Larsen MC. (2019) StAR, a bridge from ApoE, LDL, and HDL cholesterol trafficking to mitochondrial metabolism Current Opinion in Endocrine and Metabolic Research. 8: 195-205 |
| Jefcoate CR, Lee J. (2018) Cholesterol signaling in single cells: lessons from STAR and sm-FISH. Journal of Molecular Endocrinology. 60: R213-R235 |
| Seok SH, Ma ZX, Feltenberger JB, et al. (2017) Trace Derivatives of Kynurenine Potently Activate the Aryl Hydrocarbon Receptor (AHR). The Journal of Biological Chemistry |
| Lee J, Jefcoate C. (2017) Monitoring of Dual CRISPR/Cas9-Mediated Steroidogenic Acute Regulatory Protein Gene Deletion and Cholesterol Accumulation Using High-Resolution Fluorescence In Situ Hybridization in a Single Cell. Frontiers in Endocrinology. 8: 289 |