Sascha Beneke

Affiliations: 
1998-1999 ATV (Angewandte Tumor Virologie) Deutsches Krebsforschungszentrum (DKFZ), Germany 
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"Sascha Beneke"

Parents

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Rafael Alvarez-Gonzalez grad student 1998-1999 Deutsches Krebsforschungszentrum (DKFZ)
 (Co-mentored with Alexander Bürkle the PI)
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Publications

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Köritzer J, Blenn C, Bürkle A, et al. (2021) Mitochondria are devoid of poly(ADP-ribose)polymerase-1, but harbor its product oligo(ADP-ribose). Journal of Cellular Biochemistry. 122: 507-523
Rank L, Veith S, Gwosch EC, et al. (2016) Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells. Nucleic Acids Research
Buntz A, Wallrodt S, Gwosch E, et al. (2016) Real-Time Cellular Imaging of Protein Poly(ADP-ribos)ylation. Angewandte Chemie (International Ed. in English). 55: 11256-60
Fischer JM, Popp O, Gebhard D, et al. (2014) Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function. The Febs Journal. 281: 3625-41
Wyrsch P, Blenn C, Pesch T, et al. (2013) Cytosolic Ca2+ shifts as early markers of cytotoxicity. Cell Communication and Signaling : Ccs. 11: 11
Beneke S, Meyer K, Holtz A, et al. (2012) Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation. Plos One. 7: e32914
Fahrer J, Popp O, Malanga M, et al. (2010) High-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length. Biochemistry. 49: 7119-30
Weidele K, Kunzmann A, Schmitz M, et al. (2010) Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells. Biochemical Pharmacology. 80: 1103-12
Beneke S, Scherr AL, Ponath V, et al. (2010) Enzyme characteristics of recombinant poly(ADP-ribose) polymerases-1 of rat and human origin mirror the correlation between cellular poly(ADP-ribosyl)ation capacity and species-specific life span. Mechanisms of Ageing and Development. 131: 366-9
Beneke S, Cohausz O, Malanga M, et al. (2008) Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1. Nucleic Acids Research. 36: 6309-17
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