Keith Caldecott, Ph.D.

Affiliations: 
Genome Damage and Stability Centre University of Sussex, Falmer, England, United Kingdom 
Area:
Genomic Stability, Ageing, Neurodegeneration,
Website:
http://www.sussex.ac.uk/profiles/132762
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"Keith Caldecott"
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Publications

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Meroni A, Wells SE, Fonseca C, et al. (2024) DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of Cell Biology. 223
Milano L, Gautam A, Caldecott KW. (2023) DNA damage and transcription stress. Molecular Cell. 84: 70-79
Caldecott KW. (2023) Causes and consequences of DNA single-strand breaks. Trends in Biochemical Sciences. 49: 68-78
Thuresson AC, Brazina J, Akram T, et al. (2023) Novel PNKP mutations associated with reduced DNA single-strand break repair and severe microcephaly, seizures, and developmental delay. Molecular Genetics & Genomic Medicine. e2295
Gautam A, Fawcett H, Burdova K, et al. (2023) APE1-dependent base excision repair of DNA photodimers in human cells. Molecular Cell. 83: 3669-3678.e7
Zagnoli-Vieira G, Brazina J, Van Den Bogaert K, et al. (2023) Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia. Human Genetics. 142: 1417-1427
Serrano-Benitez A, Wells SE, Drummond-Clarke L, et al. (2023) Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The Embo Journal. e113190
Meroni A, Wells SE, Fonseca C, et al. (2023) DNA Combing DNA Spreading and the Separation of Sister Chromatids. Biorxiv : the Preprint Server For Biology
Wang D, Wu W, Callen E, et al. (2022) Active DNA demethylation promotes cell fate specification and the DNA damage response. Science (New York, N.Y.). 378: 983-989
Caldecott KW. (2022) DNA single-strand break repair and human genetic disease. Trends in Cell Biology
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