Jose La Rose

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"Jose La Rose"

Parents

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Janet Rossant research assistant 1997- Sick Kids (Neurotree)
Rob Rottapel research assistant 1998- Princess Margaret Cancer Centre, Toronto (Physics Tree)
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Publications

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He F, Matsumoto Y, Asano Y, et al. (2021) RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion. Frontiers in Oncology. 11: 665273
Krzyzanowski PM, Sircoulomb F, Yousif F, et al. (2019) Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer. Scientific Reports. 9: 3590
Sandí MJ, Marshall CB, Balan M, et al. (2017) MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Science Signaling. 10
Matsumoto Y, La Rose J, Lim M, et al. (2017) Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism. The Journal of Clinical Investigation
Matsumoto Y, La Rose J, Kent OA, et al. (2016) Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. The Journal of Clinical Investigation
Fine N, Dimitriou ID, Rullo J, et al. (2016) GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation. The Journal of Cell Biology. 215: 107-119
Levaot N, Voytyuk O, Dimitriou I, et al. (2011) Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism. Cell. 147: 1324-39
Levaot N, Simoncic PD, Dimitriou ID, et al. (2011) 3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions. The Journal of Clinical Investigation. 121: 3244-57
Chen G, Dimitriou ID, La Rose J, et al. (2007) The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response. Molecular and Cellular Biology. 27: 3109-22
Wu LX, La Rose J, Chen L, et al. (2005) CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway. Journal of Immunology (Baltimore, Md. : 1950). 174: 180-94
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