David A. Knecht
Affiliations: | Molecular and Cell Biology | University of Connecticut, Storrs, CT, United States |
Area:
cell motilityWebsite:
http://web.uconn.edu/mcbstaff/knecht/Knecht_Lab/Knecht_Lab.htmlGoogle:
"David A Knecht"Parents
Sign in to add mentor| Randall L. Dimond | grad student | 1982 | UW Madison | |
| (Immunological and biochemical analysis of the modification of lysosomal enzymes in the cellular slime mold Dictyostelium discoideum) | ||||
Children
Sign in to add trainee| Kathryn J. Grive | research assistant | 2007-2009 | University of Connecticut (DevTree) |
| Raymond W. Washington | grad student | 2006 | University of Connecticut |
| Renee M. Gilberti | grad student | 2011 | University of Connecticut |
| Alexandra M Goetjen | grad student | 2012-2013 | University of Connecticut (Neurotree) |
| Gaurav Joshi | grad student | 2006-2015 | University of Connecticut |
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Publications
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| Paschke P, Knecht DA, Williams TD, et al. (2019) Genetic Engineering of Dictyostelium discoideum Cells Based on Selection and Growth on Bacteria. Journal of Visualized Experiments : Jove |
| Paschke P, Knecht DA, Silale A, et al. (2018) Rapid and efficient genetic engineering of both wild type and axenic strains of Dictyostelium discoideum. Plos One. 13: e0196809 |
| Joshi GN, Gilberti RM, Knecht DA. (2017) Single Cell Analysis of Phagocytosis, Phagosome Maturation, Phagolysosomal Leakage, and Cell Death Following Exposure of Macrophages to Silica Particles. Methods in Molecular Biology (Clifton, N.J.). 1519: 55-77 |
| Tweedy L, Knecht DA, Mackay GM, et al. (2016) Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of Chemotaxis. Plos Biology. 14: e1002404 |
| Joshi GN, Goetjen AM, Knecht DA. (2015) Silica particles cause NADPH oxidase-independent ROS generation and transient phagolysosomal leakage. Molecular Biology of the Cell. 26: 3150-64 |
| Gilberti RM, Knecht DA. (2015) Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway. Molecular Biology of the Cell. 26: 518-29 |
| Muinonen-Martin AJ, Susanto O, Zhang Q, et al. (2014) Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. Plos Biology. 12: e1001966 |
| Veltman DM, Lemieux MG, Knecht DA, et al. (2014) PIP₃-dependent macropinocytosis is incompatible with chemotaxis. The Journal of Cell Biology. 204: 497-505 |
| Lemieux MG, Janzen D, Hwang R, et al. (2014) Visualization of the actin cytoskeleton: different F-actin-binding probes tell different stories. Cytoskeleton (Hoboken, N.J.). 71: 157-69 |
| Joshi GN, Knecht DA. (2014) Multi-parametric analysis of intrinsic cell death using live cell microscopy Microscopy and Microanalysis. 20: 1422-1423 |