Jason R. Burke
Affiliations: | 2012 | Chemistry | University of California, Santa Cruz, Santa Cruz, CA, United States |
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"Jason Burke"Parents
Sign in to add mentorSeth M. Rubin | grad student | 2012 | UC Santa Cruz | |
(Structural studies of retinoblastoma protein phosphorylation.) |
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Publications
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Wolf-Saxon ER, Moorman CC, Castro A, et al. (2023) Regulatory ligand binding in plant chalcone isomerase-like (CHIL) proteins. The Journal of Biological Chemistry. 104804 |
Burke JR, La Clair JJ, Philippe RN, et al. (2019) Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases Acs Catalysis. 9: 8388-8396 |
Kaltenbach M, Burke JR, Dindo M, et al. (2018) Evolution of chalcone isomerase from a noncatalytic ancestor. Nature Chemical Biology |
Pye CR, Bray WM, Brown ER, et al. (2016) A Strategy for Direct Chemical Activation of the Retinoblastoma Protein. Acs Chemical Biology |
Tokarski JS, Zupa-Fernandez A, Tredup JA, et al. (2015) Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. The Journal of Biological Chemistry. 290: 11061-74 |
Burke JR, Liban TJ, Restrepo T, et al. (2014) Multiple mechanisms for E2F binding inhibition by phosphorylation of the retinoblastoma protein C-terminal domain. Journal of Molecular Biology. 426: 245-55 |
Burke JR, Hura GL, Rubin SM. (2012) Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control. Genes & Development. 26: 1156-66 |
Balog ER, Burke JR, Hura GL, et al. (2011) Crystal structure of the unliganded retinoblastoma protein pocket domain. Proteins. 79: 2010-4 |
Burke JR, Deshong AJ, Pelton JG, et al. (2010) Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding. The Journal of Biological Chemistry. 285: 16286-93 |
Burke JR, Pelton JG, Rubin SM. (2010) Molecular Mechanisms for Phosphorylation Driven Dissociation of Rb-E2F Complexes Biophysical Journal. 98: 235a |