| Year |
Citation |
Score |
| 2018 |
Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD. Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. Journal of Medicinal Chemistry. PMID 30199635 DOI: 10.1021/Acs.Jmedchem.8B01136 |
0.566 |
|
| 2014 |
Li J, Huang J, Jeong JH, Park SJ, Wei R, Peng J, Luo Z, Chen YT, Feng Y, Luo JL. Selective TBK1/IKKi dual inhibitors with anticancer potency. International Journal of Cancer. Journal International Du Cancer. 134: 1972-80. PMID 24150799 DOI: 10.1002/Ijc.28507 |
0.411 |
|
| 2013 |
Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M, Bannister TD, Almli L, Stevens JS, Bradley B, Binder EB, Wahlestedt C, Ressler KJ. Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Science Translational Medicine. 5: 188ra73. PMID 23740899 DOI: 10.1126/Scitranslmed.3005656 |
0.554 |
|
| 2013 |
Chowdhury S, Chen YT, Fang X, Grant W, Pocas J, Cameron MD, Ruiz C, Lin L, Park H, Schröter T, Bannister TD, Lograsso PV, Feng Y. Amino acid derived quinazolines as Rock/PKA inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 1592-9. PMID 23416002 DOI: 10.1016/J.Bmcl.2013.01.109 |
0.648 |
|
| 2013 |
Chen YT, Brinen LS, Kerr ID, Hansell E, Doyle PS, McKerrow JH, Roush WR. Structure of WRR-483 bound to cruzain Plos Neglected Tropical Diseases. DOI: 10.1371/Journal.Pntd.0000825.G003 |
0.381 |
|
| 2011 |
Zhou Y, Agudelo J, Lu K, Goetz DH, Hansell E, Chen YT, Roush WR, McKerrow J, Craik CS, Amberg SM, Simmons G. Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. Antiviral Research. 92: 187-94. PMID 21820471 DOI: 10.1016/J.Antiviral.2011.07.016 |
0.484 |
|
| 2011 |
Fang X, Chen YT, Sessions EH, Chowdhury S, Vojkovsky T, Yin Y, Pocas JR, Grant W, Schröter T, Lin L, Ruiz C, Cameron MD, LoGrasso P, Bannister TD, Feng Y. Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1844-8. PMID 21349713 DOI: 10.1016/J.Bmcl.2011.01.039 |
0.67 |
|
| 2011 |
Chen YT, Vojkovsky T, Fang X, Pocas JR, Grant W, Handy AMW, Schröter T, Lograsso P, Bannister TD, Feng Y. Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitors Medchemcomm. 2: 73-75. DOI: 10.1039/C0Md00194E |
0.67 |
|
| 2010 |
Yin Y, Cameron MD, Lin L, Khan S, Schröter T, Grant W, Pocas J, Chen YT, Schürer S, Pachori A, LoGrasso P, Feng Y. Discovery of Potent and Selective Urea-Based ROCK Inhibitors and Their Effects on Intraocular Pressure in Rats. Acs Medicinal Chemistry Letters. 1: 175-9. PMID 24900192 DOI: 10.1021/Ml1000382 |
0.483 |
|
| 2010 |
Chen YT, Brinen LS, Kerr ID, Hansell E, Doyle PS, McKerrow JH, Roush WR. In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. Plos Neglected Tropical Diseases. 4. PMID 20856868 DOI: 10.1371/Journal.Pntd.0000825 |
0.507 |
|
| 2010 |
Fang X, Yin Y, Chen YT, Yao L, Wang B, Cameron MD, Lin L, Khan S, Ruiz C, Schröter T, Grant W, Weiser A, Pocas J, Pachori A, Schürer S, et al. Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors. Journal of Medicinal Chemistry. 53: 5727-37. PMID 20684608 DOI: 10.1021/Jm100579R |
0.499 |
|
| 2010 |
Sessions EH, Smolinski M, Wang B, Frackowiak B, Chowdhury S, Yin Y, Chen YT, Ruiz C, Lin L, Pocas J, Schröter T, Cameron MD, LoGrasso P, Feng Y, Bannister TD. The development of benzimidazoles as selective rho kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1939-43. PMID 20167489 DOI: 10.1016/J.Bmcl.2010.01.124 |
0.667 |
|
| 2008 |
Chen YT, Bannister TD, Weiser A, Griffin E, Lin L, Ruiz C, Cameron MD, Schürer S, Duckett D, Schröter T, LoGrasso P, Feng Y. Chroman-3-amides as potent Rho kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 6406-9. PMID 18990570 DOI: 10.1016/J.Bmcl.2008.10.080 |
0.674 |
|
| 2008 |
Chen YT, Lira R, Hansell E, McKerrow JH, Roush WR. Synthesis of macrocyclic trypanosomal cysteine protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 5860-3. PMID 18585034 DOI: 10.1016/J.Bmcl.2008.06.012 |
0.506 |
|
| 2007 |
Goetz DH, Choe Y, Hansell E, Chen YT, McDowell M, Jonsson CB, Roush WR, McKerrow J, Craik CS. Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus. Biochemistry. 46: 8744-52. PMID 17605471 DOI: 10.1021/Bi0621415 |
0.484 |
|
| 2004 |
Chen YT, Seto CT. Parallel synthesis of a library of bidentate protein tyrosine phosphatase inhibitors based on the alpha-ketoacid motif. Bioorganic & Medicinal Chemistry. 12: 3289-98. PMID 15158797 DOI: 10.1016/J.Bmc.2004.03.058 |
0.323 |
|
| 2002 |
Chen YT, Seto CT. Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases. Journal of Medicinal Chemistry. 45: 3946-52. PMID 12190316 DOI: 10.1021/Jm020093Q |
0.318 |
|
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