| Year |
Citation |
Score |
| 2022 |
Leray X, Hilton JK, Nwangwu K, Becerril A, Mikusevic V, Fitzgerald G, Amin A, Weston MR, Mindell JA. Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance. Elife. 11. PMID 35670560 DOI: 10.7554/eLife.74136 |
0.323 |
|
| 2020 |
Sampson CDD, Stewart MJ, Mindell JA, Mulligan C. Solvent accessibility changes in a Na-dependent C-dicarboxylate transporter suggest differential substrate effects in a multistep mechanism. The Journal of Biological Chemistry. 295: 18524-18538. PMID 33453852 DOI: 10.1074/jbc.RA120.013894 |
0.302 |
|
| 2020 |
Sampson CDD, Stewart MJ, Mindell JA, Mulligan C. Solvent accessibility changes in a Na-dependent C-dicarboxylate transporter suggest differential substrate effects in a multistep mechanism. The Journal of Biological Chemistry. PMID 33087444 DOI: 10.1074/jbc.RA120.013894 |
0.301 |
|
| 2019 |
Singh A, Marcoline FV, Veshaguri S, Kao AW, Bruchez M, Mindell JA, Stamou D, Grabe M. Protons in small spaces: Discrete simulations of vesicle acidification. Plos Computational Biology. 15: e1007539. PMID 31869334 DOI: 10.1371/Journal.Pcbi.1007539 |
0.343 |
|
| 2019 |
Amin A, Mindell JA. The Role of the Chloride Transporter CLC-7 in Acidification in Mouse Liver Lysosomes Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1257 |
0.358 |
|
| 2018 |
Weston MR, Mindell JA. Characterizing chloride-dependent acidification in brain Clathrin-coated vesicles. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 30383978 DOI: 10.1139/bcb-2018-0142 |
0.437 |
|
| 2018 |
Shlosman I, Marinelli F, Mindell JA, Faraldo-Gómez JD. Dissecting the Thermodynamics of Transport of a Sodium-Calcium Exchanger Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1856 |
0.348 |
|
| 2017 |
Shlosman I, Marinelli F, Faraldo-Gómez JD, Mindell JA. The prokaryotic Na+/Ca2+ exchanger NCX_Mj transports Na+ and Ca2+ in a 3:1 stoichiometry. The Journal of General Physiology. PMID 29237756 DOI: 10.1085/jgp.201711897 |
0.4 |
|
| 2017 |
Mulligan C, Mindell JA. Pinning Down the Mechanism of Transport: Probing the Structure and Function of Transporters Using Cysteine Cross-Linking and Site-Specific Labeling. Methods in Enzymology. 594: 165-202. PMID 28779840 DOI: 10.1016/bs.mie.2017.05.012 |
0.434 |
|
| 2017 |
Fitzgerald GA, Mulligan C, Mindell JA. A general method for determining secondary active transporter substrate stoichiometry. Elife. 6. PMID 28121290 DOI: 10.7554/eLife.21016 |
0.448 |
|
| 2017 |
Fitzgerald GA, Mulligan C, Mindell JA. Author response: A general method for determining secondary active transporter substrate stoichiometry Elife. DOI: 10.7554/Elife.21016.011 |
0.349 |
|
| 2017 |
Becerril AJ, Fenollar-Ferrer C, Forrest LR, Mindell JA. It Runs in the Family: Determining the Transport Mechanism of Sodium/Dicarboxylate Symporter hNaDC3 Biophysical Journal. 112: 129a-130a. DOI: 10.1016/J.Bpj.2016.11.720 |
0.499 |
|
| 2016 |
Marcoline FV, Ishida Y, Mindell JA, Nayak S, Grabe M. A mathematical model of osteoclast acidification during bone resorption. Bone. PMID 27650914 DOI: 10.1016/J.Bone.2016.09.007 |
0.428 |
|
| 2016 |
Mulligan C, Fenollar-Ferrer C, Fitzgerald GA, Vergara-Jaque A, Kaufmann D, Li Y, Forrest LR, Mindell JA. The bacterial dicarboxylate transporter VcINDY uses a two-domain elevator-type mechanism. Nature Structural & Molecular Biology. 23: 256-63. PMID 26828963 DOI: 10.1038/Nsmb.3166 |
0.439 |
|
| 2016 |
Amin A, Weston M, Mindell JA. Role of Counterions in Acidification in Mouse Liver Lysosomes Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.789 |
0.404 |
|
| 2016 |
Fenollar-Ferrer C, Anselmi C, Vergara Jaque A, Ali Karimi-Verzaneh H, Poblete-Vilches H, Mulligan C, Forster IC, Mindell JA, Faraldo-Gómez JD, Forrest LR. Computational Studies of Elevator-Like Movements in Secondary Transport Biophysical Journal. 110: 626a-627a. DOI: 10.1016/J.Bpj.2015.11.3359 |
0.469 |
|
| 2015 |
Vergara-Jaque A, Fenollar-Ferrer C, Mulligan C, Mindell JA, Forrest LR. Family resemblances: A common fold for some dimeric ion-coupled secondary transporters. The Journal of General Physiology. 146: 423-34. PMID 26503722 DOI: 10.1085/Jgp.201511481 |
0.489 |
|
| 2015 |
Mulligan C, Fitzgerald GA, Mindell JA. Assessing Protomer Independence of the Dimeric C4-Dicarboxylate Transporter, Vcindy Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2515 |
0.396 |
|
| 2015 |
Fitzgerald GA, Mulligan C, Mindell JA. Transport Coupling Stoichiometry Determination of Electrogenic Secondary Transporters Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.180 |
0.47 |
|
| 2015 |
Lioi SB, Weston MR, Mindell JA. Sirna Knockdown of ClC-7 Produces a Lysosomal pH Increase Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1694 |
0.324 |
|
| 2015 |
Veshaguri S, Christensen SM, Møller MP, Ghale G, Lohr C, Christensen AL, Tutkus M, Kemmer G, Jørgensen IL, Justesen BH, Curran P, Pomorski TG, Mindell J, Stamou D. Development of a Fluorescence-Based Assay for Functional Studies of Transporter Proteins on the Single Molecule Level Biophysical Journal. 108: 187a. DOI: 10.1016/J.Bpj.2014.11.1032 |
0.587 |
|
| 2014 |
Parker JL, Mindell JA, Newstead S. Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter. Elife. 3. PMID 25457052 DOI: 10.7554/Elife.04273 |
0.438 |
|
| 2014 |
Mulligan C, Fitzgerald GA, Wang DN, Mindell JA. Functional characterization of a Na+-dependent dicarboxylate transporter from Vibrio cholerae. The Journal of General Physiology. 143: 745-59. PMID 24821967 DOI: 10.1085/jgp.201311141 |
0.489 |
|
| 2014 |
Parker JL, Mindell JA, Newstead S. Author response: Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter Elife. DOI: 10.7554/Elife.04273.016 |
0.373 |
|
| 2014 |
Courville P, Mindell JA. Roles of Cytoplasmic Ions in Lysosomal Acidification Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.847 |
0.397 |
|
| 2014 |
Lohr C, Christensen AL, Veshaguri S, Tutkus M, Iversen L, Kemmer G, Yaffe D, Zollmann T, Curran P, Schuldiner S, Tampé R, Pomorski T, Mindell J, Stamou D. Single Liposomes Used to Study the Activity of Individual Transporters Biophysical Journal. 106: 229a. DOI: 10.1016/J.Bpj.2013.11.1339 |
0.576 |
|
| 2013 |
Mulligan C, Mindell JA. Mechanism of transport modulation by an extracellular loop in an archaeal excitatory amino acid transporter (EAAT) homolog. The Journal of Biological Chemistry. 288: 35266-76. PMID 24155238 DOI: 10.1074/jbc.M113.508408 |
0.464 |
|
| 2013 |
Ishida Y, Nayak S, Mindell JA, Grabe M. A model of lysosomal pH regulation. The Journal of General Physiology. 141: 705-20. PMID 23712550 DOI: 10.1085/Jgp.201210930 |
0.423 |
|
| 2013 |
Mulligan C, Mindell JA. The 3-4 Loop of GltPh, an Archaeal Glutamate Transporter Homolog Mediates the Movement of the Transport Domain Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.380 |
0.464 |
|
| 2013 |
Silverman D, Mindell JA. Dissection of Proton Inhibition Mechanism in the H+/Cl− Exchanger, CLC-7 Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3472 |
0.407 |
|
| 2012 |
Mindell JA. Lysosomal acidification mechanisms. Annual Review of Physiology. 74: 69-86. PMID 22335796 DOI: 10.1146/annurev-physiol-012110-142317 |
0.443 |
|
| 2010 |
Compton EL, Mindell JA. Bacterial Ion Channels. Ecosal Plus. 4. PMID 26443789 DOI: 10.1128/ecosalplus.3.3.2 |
0.309 |
|
| 2010 |
Mindell JA. Structural biology. The Tao of chloride transporter structure. Science (New York, N.Y.). 330: 601-2. PMID 21030639 DOI: 10.1126/science.1198306 |
0.42 |
|
| 2010 |
Compton EL, Taylor EM, Mindell JA. The 3-4 loop of an archaeal glutamate transporter homolog experiences ligand-induced structural changes and is essential for transport. Proceedings of the National Academy of Sciences of the United States of America. 107: 12840-5. PMID 20615993 DOI: 10.1073/pnas.1003046107 |
0.491 |
|
| 2010 |
Francis D, Cafiso DS, Mindell JA. Detection of Substrate-Dependent Conformational Changes in HP1 of the Glutamate Transporter GltPH Biophysical Journal. 98: 686a. DOI: 10.1016/J.Bpj.2009.12.3767 |
0.434 |
|
| 2010 |
Goh H, Broccio M, Shenoy S, Heinrich F, Mindell JA, Lösche M. Functional Incorporation of KcsA into Tethered Lipid Bilayer Membranes Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2912 |
0.385 |
|
| 2009 |
Knepper MA, Mindell JA. Structural biology: Molecular coin slots for urea. Nature. 462: 733-4. PMID 20010678 DOI: 10.1038/462733A |
0.436 |
|
| 2009 |
Ryan RM, Compton EL, Mindell JA. Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii. The Journal of Biological Chemistry. 284: 17540-8. PMID 19380583 DOI: 10.1074/Jbc.M109.005926 |
0.637 |
|
| 2009 |
Compton EL, Curran P, Mindell JA. Detecting Transport-related Conformational Changes In The Glutamate Transporter Homologue, GltPh. Biophysical Journal. 96: 382a. DOI: 10.1016/J.Bpj.2008.12.2860 |
0.635 |
|
| 2009 |
Francis DJ, Mindell JA. Exploring the Gating Mechanism of the Glutamate Transporter GltPh Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.1338 |
0.466 |
|
| 2008 |
Csanády L, Mindell JA. The twain shall meet: channels, transporters and things between. Meeting on Membrane Transport in Flux: the Ambiguous Interface Between Channels and Pumps. Embo Reports. 9: 960-5. PMID 18772896 DOI: 10.1038/Embor.2008.172 |
0.542 |
|
| 2008 |
Mindell JA. The chloride channel's appendix. Nature Structural & Molecular Biology. 15: 781-3. PMID 18679432 DOI: 10.1038/nsmb0808-781 |
0.552 |
|
| 2008 |
Osteen JD, Mindell JA. Insights into the ClC-4 transport mechanism from studies of Zn2+ inhibition. Biophysical Journal. 95: 4668-75. PMID 18658230 DOI: 10.1529/Biophysj.108.137158 |
0.765 |
|
| 2008 |
Graves AR, Curran PK, Smith CL, Mindell JA. The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes. Nature. 453: 788-92. PMID 18449189 DOI: 10.1038/nature06907 |
0.764 |
|
| 2007 |
Ryan RM, Mindell JA. The uncoupled chloride conductance of a bacterial glutamate transporter homolog. Nature Structural & Molecular Biology. 14: 365-71. PMID 17435767 DOI: 10.1038/Nsmb1230 |
0.624 |
|
| 2006 |
Bell SP, Curran PK, Choi S, Mindell JA. Site-directed fluorescence studies of a prokaryotic ClC antiporter. Biochemistry. 45: 6773-82. PMID 16734414 DOI: 10.1021/bi0523815 |
0.647 |
|
| 2005 |
Phillips LR, Milescu M, Li-Smerin Y, Mindell JA, Kim JI, Swartz KJ. Voltage-sensor activation with a tarantula toxin as cargo. Nature. 436: 857-60. PMID 16094370 DOI: 10.1038/Nature03873 |
0.341 |
|
| 2003 |
Maduke M, Mindell JA. The poststructural festivities begin. Neuron. 38: 1-3. PMID 12691656 DOI: 10.1016/S0896-6273(03)00204-6 |
0.652 |
|
| 2002 |
Pirruccello MM, Grigorieff N, Mindell JA. Electron diffraction of a bacterial ClC-type chloride channel. Novartis Foundation Symposium. 245: 193-203; discussion . PMID 12027008 DOI: 10.1002/0470868759.Ch14 |
0.411 |
|
| 2001 |
Mindell JA, Maduke M, Miller C, Grigorieff N. Projection structure of a ClC-type chloride channel at 6.5 A resolution. Nature. 409: 219-23. PMID 11196649 DOI: 10.1038/35051631 |
0.722 |
|
| 2001 |
Mindell JA, Maduke M. ClC chloride channels. Genome Biology. 2: REVIEWS3003. PMID 11182894 DOI: 10.1186/Gb-2001-2-2-Reviews3003 |
0.707 |
|
| 2001 |
Mindell J, Maduke M. CIC chloride channels Genome Biology. 2. |
0.32 |
|
| 2000 |
Maduke M, Miller C, Mindell JA. A decade of CLC chloride channels: structure, mechanism, and many unsettled questions. Annual Review of Biophysics and Biomolecular Structure. 29: 411-38. PMID 10940254 DOI: 10.1146/Annurev.Biophys.29.1.411 |
0.714 |
|
| 1998 |
Mindell JA. Swimming through the hydrophobic sea: new insights in protein translocation. Proceedings of the National Academy of Sciences of the United States of America. 95: 4081-3. PMID 9539690 DOI: 10.1073/pnas.95.8.4081 |
0.316 |
|
| 1994 |
Silverman JA, Mindell JA, Finkelstein A, Shen WH, Collier RJ. Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain. The Journal of Biological Chemistry. 269: 22524-32. PMID 7521329 |
0.494 |
|
| 1994 |
Mindell JA, Silverman JA, Collier RJ, Finkelstein A. Structure-function relationships in diphtheria toxin channels: III. Residues which affect the cis pH dependence of channel conductance. The Journal of Membrane Biology. 137: 45-57. PMID 7516434 DOI: 10.1007/Bf00234997 |
0.619 |
|
| 1994 |
Mindell JA, Silverman JA, Collier RJ, Finkelstein A. Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH. The Journal of Membrane Biology. 137: 29-44. PMID 7516433 DOI: 10.1007/Bf00234996 |
0.622 |
|
| 1994 |
Silverman JA, Mindell JA, Zhan H, Finkelstein A, Collier RJ. Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain. The Journal of Membrane Biology. 137: 17-28. PMID 7516432 DOI: 10.1007/Bf00234995 |
0.581 |
|
| 1994 |
Mindell JA, Zhan H, Huynh PD, Collier RJ, Finkelstein A. Reaction of diphtheria toxin channels with sulfhydryl-specific reagents: observation of chemical reactions at the single molecule level. Proceedings of the National Academy of Sciences of the United States of America. 91: 5272-6. PMID 7515494 DOI: 10.1073/Pnas.91.12.5272 |
0.581 |
|
| 1993 |
vanderSpek JC, Mindell JA, Finkelstein A, Murphy JR. Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. The Journal of Biological Chemistry. 268: 12077-82. PMID 8505330 |
0.434 |
|
| 1993 |
Cabiaux V, Mindell J, Collier RJ. Membrane translocation and channel-forming activities of diphtheria toxin are blocked by replacing isoleucine 364 with lysine. Infection and Immunity. 61: 2200-2. PMID 7683003 DOI: 10.1128/Iai.61.5.2200-2202.1993 |
0.439 |
|
| 1992 |
Cabiaux V, Brasseur R, Mindell J, Ruysschaert JM. Computer modelling of the transmembrane channel formed by a CNBr peptide of diphtheria toxin B fragment Fems Microbiology Letters. 105: 113-119. PMID 1384591 DOI: 10.1016/0378-1097(92)90081-X |
0.383 |
|
| 1992 |
Mindell JA, Silverman JA, Collier RJ, Finkelstein A. Locating a residue in the diphtheria toxin channel. Biophysical Journal. 62: 41-4. PMID 1376171 DOI: 10.1016/S0006-3495(92)81772-1 |
0.61 |
|
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