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Johan Thevelein - Publications

Affiliations: 
Molecular Microbiology Katholieke Universiteit Leuven, Leuven, Vlaanderen, Belgium 
Area:
the molecular genetics and biochemistry of nutrient sensing and signaling in yeast (Saccharomyces cerevisiae); the use of industrial yeast strains for several biotechnological and medical applications
Website:
http://www.vib.be/en/research/scientists/Pages/Johan-Thevelein-Lab.aspx

109 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Paulussen F, Kulkarni CP, Stolz F, Lescrinier E, De Graeve S, Lambin S, Marchand A, Chaltin P, In't Veld P, Mebis J, Tavernier J, Van Dijck P, Luyten W, Thevelein JM. The β2-adrenergic receptor in the apical membrane of intestinal enterocytes senses sugars to stimulate glucose uptake from the gut. Frontiers in Cell and Developmental Biology. 10: 1041930. PMID 36699012 DOI: 10.3389/fcell.2022.1041930  0.302
2021 Kulkarni CP, Thevelein JM, Luyten W. Characterization of SGLT1-mediated glucose transport in Caco-2 cell monolayers, and absence of its regulation by sugar or epinephrine. European Journal of Pharmacology. 173925. PMID 33545159 DOI: 10.1016/j.ejphar.2021.173925  0.311
2021 Kulkarni CP, Thevelein JM, Luyten W. Characterization of SGLT1-mediated glucose transport in Caco-2 cell monolayers, and absence of its regulation by sugar or epinephrine. European Journal of Pharmacology. 173925. PMID 33545159 DOI: 10.1016/j.ejphar.2021.173925  0.311
2020 Van Zeebroeck G, Demuyser L, Zhang Z, Cottignie I, Thevelein JM. Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA. Microbial Cell (Graz, Austria). 8: 17-27. PMID 33490229 DOI: 10.15698/mic2021.01.740  0.336
2020 Van Leemputte F, Vanthienen W, Wijnants S, Van Zeebroeck G, Thevelein JM. Aberrant Intracellular pH Regulation Limiting Glyceraldehyde-3-Phosphate Dehydrogenase Activity in the Glucose-Sensitive Yeast Δ Mutant. Mbio. 11. PMID 33109759 DOI: 10.1128/mBio.02199-20  0.412
2018 Alves SL, Thevelein JM, Stambuk BU. Extracellular maltotriose hydrolysis by Saccharomyces cerevisiae cells lacking the AGT1 permease. Letters in Applied Microbiology. 67: 377-383. PMID 29992585 DOI: 10.1111/lam.13048  0.312
2018 Steyfkens F, Zhang Z, Van Zeebroeck G, Thevelein JM. Multiple Transceptors for Macro- and Micro-Nutrients Control Diverse Cellular Properties Through the PKA Pathway in Yeast: A Paradigm for the Rapidly Expanding World of Eukaryotic Nutrient Transceptors Up to Those in Human Cells. Frontiers in Pharmacology. 9: 191. PMID 29662449 DOI: 10.3389/fphar.2018.00191  0.392
2017 Conrad M, Kankipati HN, Kimpe M, Van Zeebroeck G, Zhang Z, Thevelein JM. The nutrient transceptor/PKA pathway functions independently of TOR and responds to leucine and Gcn2 in a TOR-independent manner. Fems Yeast Research. 17. PMID 28810702 DOI: 10.1093/femsyr/fox048  0.307
2014 Conrad M, Schothorst J, Kankipati HN, Van Zeebroeck G, Rubio-Texeira M, Thevelein JM. Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. Fems Microbiology Reviews. 38: 254-99. PMID 24483210 DOI: 10.1111/1574-6976.12065  0.304
2012 Castermans D, Somers I, Kriel J, Louwet W, Wera S, Versele M, Janssens V, Thevelein JM. Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Research. 22: 1058-77. PMID 22290422 DOI: 10.1038/cr.2012.20  0.403
2010 de Melo HF, Bonini BM, Thevelein J, Simões DA, Morais MA. Physiological and molecular analysis of the stress response of Saccharomyces cerevisiae imposed by strong inorganic acid with implication to industrial fermentations. Journal of Applied Microbiology. 109: 116-27. PMID 20002866 DOI: 10.1111/j.1365-2672.2009.04633.x  0.387
2009 Noubhani A, Bunoust O, Bonini BM, Thevelein JM, Devin A, Rigoulet M. The trehalose pathway regulates mitochondrial respiratory chain content through hexokinase 2 and cAMP in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 27229-34. PMID 19620241 DOI: 10.1074/jbc.M109.029454  0.308
2009 Lundh F, Mouillon JM, Samyn D, Stadler K, Popova Y, Lagerstedt JO, Thevelein JM, Persson BL. Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry. 48: 4497-505. PMID 19348508 DOI: 10.1021/bi9001198  0.344
2008 Saerens SM, Verbelen PJ, Vanbeneden N, Thevelein JM, Delvaux FR. Monitoring the influence of high-gravity brewing and fermentation temperature on flavour formation by analysis of gene expression levels in brewing yeast. Applied Microbiology and Biotechnology. 80: 1039-51. PMID 18751696 DOI: 10.1007/s00253-008-1645-5  0.347
2008 Thevelein JM, Bonini BM, Castermans D, Haesendonckx S, Kriel J, Louwet W, Thayumanavan P, Popova Y, Rubio-Texeira M, Schepers W, Vandormael P, Van Zeebroeck G, Verhaert P, Versele M, Voordeckers K. Novel mechanisms in nutrient activation of the yeast protein kinase A pathway. Acta Microbiologica Et Immunologica Hungarica. 55: 75-89. PMID 18595314 DOI: 10.1556/Amicr.55.2008.2.1  0.373
2008 Nazarko VY, Futej KO, Thevelein JM, Sibirny AA. Differences in glucose sensing and signaling for pexophagy between the baker's yeast Saccharomyces cerevisiae and the methylotrophic yeast Pichia pastoris. Autophagy. 4: 381-4. PMID 18227642  0.342
2008 Nazarko VY, Thevelein JM, Sibirny AA. G-protein-coupled receptor Gpr1 and G-protein Gpa2 of cAMP-dependent signaling pathway are involved in glucose-induced pexophagy in the yeast Saccharomyces cerevisiae. Cell Biology International. 32: 502-4. PMID 18096414 DOI: 10.1016/j.cellbi.2007.11.001  0.305
2008 Berthels NJ, Cordero Otero RR, Bauer FF, Pretorius IS, Thevelein JM. Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains. Applied Microbiology and Biotechnology. 77: 1083-91. PMID 17955190 DOI: 10.1007/s00253-007-1231-2  0.332
2008 Van de Velde S, Thevelein JM. Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae. Eukaryotic Cell. 7: 286-93. PMID 17890371 DOI: 10.1128/EC.00276-07  0.404
2006 Van Nuland A, Vandormael P, Donaton M, Alenquer M, Lourenço A, Quintino E, Versele M, Thevelein JM. Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast. Molecular Microbiology. 59: 1485-505. PMID 16468990 DOI: 10.1111/j.1365-2958.2005.05043.x  0.359
2005 Maidan MM, De Rop L, Serneels J, Exler S, Rupp S, Tournu H, Thevelein JM, Van Dijck P. The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans. Molecular Biology of the Cell. 16: 1971-86. PMID 15673611 DOI: 10.1091/mbc.E04-09-0780  0.335
2005 Avonce N, Leyman B, Thevelein J, Iturriaga G. Trehalose metabolism and glucose sensing in plants. Biochemical Society Transactions. 33: 276-9. PMID 15667325 DOI: 10.1042/BST0330276  0.361
2005 Thevelein JM, Geladé R, Holsbeeks I, Lagatie O, Popova Y, Rolland F, Stolz F, Van de Velde S, Van Dijck P, Vandormael P, Van Nuland A, Van Roey K, Van Zeebroeck G, Yan B. Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast. Biochemical Society Transactions. 33: 253-6. PMID 15667319 DOI: 10.1042/BST0330253  0.385
2004 Verstrepen KJ, Iserentant D, Malcorps P, Derdelinckx G, Van Dijck P, Winderickx J, Pretorius IS, Thevelein JM, Delvaux FR. Glucose and sucrose: hazardous fast-food for industrial yeast? Trends in Biotechnology. 22: 531-7. PMID 15450747 DOI: 10.1016/j.tibtech.2004.08.001  0.347
2004 Colombo S, Ronchetti D, Thevelein JM, Winderickx J, Martegani E. Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 279: 46715-22. PMID 15339905 DOI: 10.1074/jbc.M405136200  0.324
2004 Berthels NJ, Cordero Otero RR, Bauer FF, Thevelein JM, Pretorius IS. Discrepancy in glucose and fructose utilisation during fermentation by Saccharomyces cerevisiae wine yeast strains. Fems Yeast Research. 4: 683-9. PMID 15093771 DOI: 10.1016/j.femsyr.2004.02.005  0.314
2004 Tisi R, Belotti F, Wera S, Winderickx J, Thevelein JM, Martegani E. Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast. Current Genetics. 45: 83-9. PMID 14618376 DOI: 10.1007/s00294-003-0465-5  0.331
2004 Thevelein J. Nutrient sensing through the plasma membrane of eukaryotic cells, Cirencester, UK, 25-29 September, 2004 Fems Yeast Research. 5: 303-305. DOI: 10.1016/j.femsyr.2004.10.005  0.404
2003 Verstrepen KJ, Derdelinckx G, Dufour JP, Winderickx J, Pretorius IS, Thevelein JM, Delvaux FR. The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. Fems Yeast Research. 4: 285-96. PMID 14654433 DOI: 10.1016/S1567-1356(03)00166-1  0.356
2003 Bonini BM, Van Dijck P, Thevelein JM. Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae Tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe. Biochimica Et Biophysica Acta. 1606: 83-93. PMID 14507429 DOI: 10.1016/S0005-2728(03)00086-0  0.387
2003 Portela P, Van Dijck P, Thevelein JM, Moreno S. Activation state of protein kinase A as measured in permeabilised Saccharomyces cerevisiae cells correlates with PKA-controlled phenotypes in vivo. Fems Yeast Research. 3: 119-26. PMID 12702255 DOI: 10.1016/S1567-1356(02)00158-7  0.409
2003 Giots F, Donaton MC, Thevelein JM. Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Molecular Microbiology. 47: 1163-81. PMID 12581367 DOI: 10.1046/j.1365-2958.2003.03365.x  0.37
2002 Thevelein J. The XXth International Conference on Yeast Genetics and Molecular Biology, Prague. Fems Yeast Research. 1: 339-40. PMID 12702339 DOI: 10.1016/S1567-1356(01)00044-7  0.335
2002 Rolland F, Winderickx J, Thevelein JM. Glucose-sensing and -signalling mechanisms in yeast. Fems Yeast Research. 2: 183-201. PMID 12702307 DOI: 10.1016/S1567-1356(02)00046-6  0.362
2002 Brandão RL, Etchebehere L, Queiroz CC, Trópia MJ, Ernandes JR, Gonçalves T, Loureiro-Dias MC, Winderickx J, Thevelein JM, Leiper FC, Carling D, Castro IM. Evidence for involvement of Saccharomyces cerevisiae protein kinase C in glucose induction of HXT genes and derepression of SUC2. Fems Yeast Research. 2: 93-102. PMID 12702297 DOI: 10.1111/J.1567-1364.2002.Tb00074.X  0.48
2002 Van Dijck P, De Rop L, Szlufcik K, Van Ael E, Thevelein JM. Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation Infection and Immunity. 70: 1772-1782. PMID 11895938 DOI: 10.1128/IAI.70.4.1772-1782.2002  0.306
2001 Rolland F, Wanke V, Cauwenberg L, Ma P, Boles E, Vanoni M, De Winde JH, Thevelein JM, Winderickx J. The role of hexose transport and phosphorylation in cAMP signalling in the yeast Saccharomyces cerevisiae Fems Yeast Research. 1: 33-45. PMID 12702461 DOI: 10.1016/S1567-1356(01)00002-2  0.457
2001 Bergsma JCT, Kasri NN, Donaton MCV, De Wever V, Tisi R, De Winde JH, Martegani E, Thevelein JM, Wera S. Ptdlns(4,5)P2 and phospholipase C-independent lns(1,4,5)P3 signals induced by a nitrogen source in nitrogen-starved yeast cells Biochemical Journal. 359: 517-523. PMID 11672425 DOI: 10.1042/0264-6021:3590517  0.344
2001 Versele M, Thevelein JM. Lre1 affects chitinase expression, trehalose accumulation and heat resistance through inhibition of the Cbk1 protein kinase in Saccharomyces cerevisiae Molecular Microbiology. 41: 1311-1326. PMID 11580836 DOI: 10.1046/j.1365-2958.2001.02590.x  0.315
2001 Fillinger S, Chaveroche MK, van Dijck P, de Vries R, Ruijter G, Thevelein J, d'Enfert C. Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans Microbiology. 147: 1851-1862. PMID 11429462 DOI: 10.1099/00221287-147-7-1851  0.417
2001 Sugajska E, Swiatek W, Zabrocki P, Geyskens I, Thevelein JM, Zolnierowicz S, Wera S. Multiple effects of protein phosphatase 2A on nutrient-induced signalling in the yeast Saccharomyces cerevisiae Molecular Microbiology. 40: 1020-1026. PMID 11401708 DOI: 10.1046/j.1365-2958.2001.02449.x  0.417
2001 Rolland F, Winderickx J, Thevelein JM. Glucose-sensing mechanisms in eukaryotic cells Trends in Biochemical Sciences. 26: 310-317. PMID 11343924 DOI: 10.1016/S0968-0004(01)01805-9  0.326
2001 Van Vaeck C, Wera S, Van Dijck P, Thevelein JM. Analysis and modification of trehalose 6-phosphate levels in the yeast Saccharomyces cerevisiae with the use of Bacillus subtilis phosphotrehalase Biochemical Journal. 353: 157-162. PMID 11115409 DOI: 10.1042/0264-6021:3530157  0.371
2001 Pardons K, Rolland F, Winderickx J, Thevelein J. Involvement of the sugar kinases in the activation of the glucose repression pathway and the cAMP pathway in Saccharomyces cerevisiae Bmc News and Views. 1. DOI: 10.1186/2048-4623-1-S1-P017  0.351
2001 Holsbeeks I, Donaton M, Lagatie O, Crauwels M, Winderickx J, Thevelein J. Protein kinase A control in glucose and nitrogen sensing in Saccharomyces Cerevisiae Bmc News and Views. 1. DOI: 10.1186/2048-4623-1-S1-P012  0.305
2001 Geladé R, Buainain L, Versele M, Thevelein J. Effector and putative Gβ-subunit of the Gα-protein Gpa2 involved in glucose-induced stimulation of cAMP synthesis in yeast Bmc News and Views. 1. DOI: 10.1186/2048-4623-1-S1-P008  0.31
2000 Rolland F, De Winde JH, Lemaire K, Boles E, Thevelein JM, Winderickx J. Glucose-induced cAMP signalling in yeast requires both a G-protein coupled receptor system for extracellular glucose detection and a separable hexose kinase-dependent sensing process Molecular Microbiology. 38: 348-358. PMID 11069660 DOI: 10.1046/j.1365-2958.2000.02125.x  0.372
2000 Bonini BM, Van Vaeck C, Larsson C, Gustafsson L, Ma P, Winderickx J, Van Dijck P, Thevelein JM. Expression of Escherichia coli otsA in a Saccharomyces cerevisiae tps1 mutant restores trehalose 6-phosphate levels and partly restores growth and fermentation with glucose and control of glucose influx into glycolysis Biochemical Journal. 350: 261-268. PMID 10926852 DOI: 10.1042/0264-6021:3500261  0.41
2000 Noubhani A, Bunoust O, Rigoulet M, Thevelein JM. Reconstitution of ethanolic fermentation in permeabilized spheroplasts of wild-type and trehalose-6-phosphate synthase mutants of the yeast Saccharomyces cerevisiae European Journal of Biochemistry. 267: 4566-4576. PMID 10880982 DOI: 10.1046/j.1432-1327.2000.01511.x  0.356
2000 Eliasson A, Boles E, Johansson B, Österberg M, Thevelein JM, Spencer-Martins I, Juhnke H, Hahn-Hägerdal B. Xylulose fermentation by mutant and wild-type strains of Zygosaccharomyces and Saccharomyces cerevisiae Applied Microbiology and Biotechnology. 53: 376-382. PMID 10803891 DOI: 10.1007/S002530051629  0.328
2000 Dumortier F, Vanhalewyn M, Debast G, Colombo S, Ma P, Winderickx J, Van Dijck P, Thevelein JM. A specific mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1(K1876M), eliminates glucose- and acidification-induced cAMP signalling and delays glucose-induced loss of stress resistance International Journal of Food Microbiology. 55: 103-107. PMID 10791726 DOI: 10.1016/S0168-1605(00)00184-7  0.388
1999 Versele M, De Winde JH, Thevelein JM. A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2 Embo Journal. 18: 5577-5591. PMID 10523302 DOI: 10.1093/emboj/18.20.5577  0.353
1999 Kraakman LS, Winderickx J, Thevelein JM, De Winde JH. Structure-function analysis of yeast hexokinase: Structural requirements for triggering cAMP signalling and catabolite repression Biochemical Journal. 343: 159-168. PMID 10493925 DOI: 10.1042/0264-6021:3430159  0.468
1999 Thevelein JM, De Winde JH. Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae Molecular Microbiology. 33: 904-918. PMID 10476026 DOI: 10.1046/j.1365-2958.1999.01538.x  0.417
1999 Ma P, Winderickx J, Nauwelaers D, Dumortier F, De Doncker A, Thevelein JM, Van Dijck P. Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G2 arrest Yeast. 15: 1097-1109. PMID 10455233 DOI: 10.1002/(SICI)1097-0061(199908)15:11<1097::AID-YEA437>3.0.CO;2-B  0.3
1999 Vanhalewyn M, Dumortier F, Debast G, Colombo S, Ma P, Winderickx J, Van Dijck P, Thevelein JM. A mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1(K1876M), specifically affects glucose- and acidification-induced cAMP signalling and not the basal cAMP level Molecular Microbiology. 33: 363-376. PMID 10411752 DOI: 10.1046/j.1365-2958.1999.01479.x  0.374
1999 Kraakman L, Lemaire K, Ma P, Teunlssen AWRH, Donaton MCV, Van Dijck P, Winderickx J, De Winde JH, Thevelein JM. A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose Molecular Microbiology. 32: 1002-1012. PMID 10361302 DOI: 10.1046/j.1365-2958.1999.01413.x  0.401
1999 Hohmann S, Winderickx J, De Winde JH, Valckx D, Cobbaert P, Luyten K, De Meirsman C, Ramos J, Thevelein JM. Novel alleles of yeast hexokinase PII with distinct effects on catalytic activity and catabolite repression of SUC2 Microbiology. 145: 703-714. PMID 10217505  0.347
1999 Planta RJ, Brown AJP, Cadahia JL, Cerdan ME, Jonge MD, Gent ME, Hayes A, Kolen CPAM, Lombardia LJ, Sefton M, Oliver SG, Thevelein J, Tournu H, Delft YJv, Verbart DJ, et al. Transcript Analysis Of 250 Novel Yeast Genes From Chromosome Xiv Yeast. 15: 329-350. PMID 10206192 DOI: 10.1002/(Sici)1097-0061(19990315)15:4<329::Aid-Yea360>3.0.Co;2-C  0.39
1999 Ma P, Wera S, Van Dijck P, Thevelein JM. The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae has a specific function in controlling agonist- induced cAMP signaling Molecular Biology of the Cell. 10: 91-104. PMID 9880329  0.367
1998 Bell W, Sunt W, Hohmann S, Wera S, Reinders A, De Virgilio C, Wiemken A, Thevelein JM. Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex Journal of Biological Chemistry. 273: 33311-33319. PMID 9837904 DOI: 10.1074/jbc.273.50.33311  0.35
1998 Coccetti P, Tisi R, Martegani E, Souza Teixeira L, Lopes Brandão R, De Miranda Castro I, Thevelein JM. The PLC1 encoded phospholipase C in the yeast Saccharomyces cerevisiae is essential for glucose-induced phosphatidylinositol turnover and activation of plasma membrane H+-ATPase Biochimica Et Biophysica Acta - Molecular Cell Research. 1405: 147-154. PMID 9784626 DOI: 10.1016/S0167-4889(98)00099-8  0.381
1998 Colombo S, Ma P, Cauwenberg L, Winderickx J, Crauwels M, Teunissen A, Nauwelaers D, De Winde JH, Gorwa MF, Colavizza D, Thevelein JM. Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae Embo Journal. 17: 3326-3341. PMID 9628870 DOI: 10.1093/emboj/17.12.3326  0.392
1998 Ernandes JR, De Meirsman C, Rolland F, Winderickx J, De Winde J, Brandão RL, Thevelein JM. During the initiation of fermentation overexpression of hexokinase PII in yeast transiently causes a similar deregulation of glycolysis as deletion of Tps1 Yeast. 14: 255-269. PMID 9580251 DOI: 10.1002/(SICI)1097-0061(199802)14:3<255::AID-YEA228>3.0.CO;2-N  0.385
1998 Hounsa CG, Brandt EV, Thevelein J, Hohmann S, Prior BA. Role of trehalose in survival of Saccharomyces cerevisiae under osmotic stress Microbiology. 144: 671-680. PMID 9534237 DOI: 10.1099/00221287-144-3-671  0.35
1997 Wera S, Ma P, Thevelein JM. Glucose exerts opposite effects on mRNA versus protein and activity levels of Pde1, the low-affinity cAMP phosphodiesterase from budding yeast, Saccharomyces cerevisiae Febs Letters. 420: 147-150. PMID 9459299 DOI: 10.1016/S0014-5793(97)01508-1  0.369
1997 Ma P, Gonçalves T, Maretzek A, Dias MCL, Thevelein JM. The lag phase rather than the exponential-growth phase on glucose is associated with a higher cAMP level in wild-type and cAPK-attenuated strains of the yeast Saccharomyces cerevisiae Microbiology. 143: 3451-3459. PMID 9387223  0.399
1997 Crauwels M, Donaton MCV, Pernambuco MB, Winderickx J, De Winde JH, Thevelein JM. The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway Microbiology. 143: 2627-2637. PMID 9274016  0.41
1997 Ansell R, Granath K, Hohmann S, Thevelein JM, Adler L. The two isoenzymes for yeast NAD+-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation Embo Journal. 16: 2179-2187. PMID 9171333 DOI: 10.1093/emboj/16.9.2179  0.338
1997 Ferreira JC, Thevelein JM, Hohmann S, Paschoalin VMF, Trugo LC, Panek AD. Trehalose accumulation in mutants of Saccharomyces cerevisiae deleted in the UDPG-dependent trehalose synthase-phosphatase complex Biochimica Et Biophysica Acta - General Subjects. 1335: 40-50. PMID 9133641 DOI: 10.1016/S0304-4165(96)00127-4  0.395
1997 Amaral FC, Van Dijck P, Nicoli JR, Thevelein JM. Molecular cloning of the neutral trehalase gene from Kluyveromyces lactis and the distinction between neutral and acid trehalases Archives of Microbiology. 167: 202-208. PMID 9075620 DOI: 10.1007/s002030050436  0.353
1996 De Winde JH, Crauwels M, Hohmann S, Thevelein JM, Winderickx J. Differential requirement of the yeast sugar kinases for sugar sensing in establishing the catabolite-repressed state European Journal of Biochemistry. 241: 633-643. PMID 8917466 DOI: 10.1111/j.1432-1033.1996.00633.x  0.334
1996 Hohmann S, Bell W, Neves MJ, Valckx D, Thevelein JM. Evidence for trehalose-6-phosphate-dependent and-independent mechanisms in the control of sugar influx into yeast glycolysis Molecular Microbiology. 20: 981-991. PMID 8809751 DOI: 10.1111/J.1365-2958.1996.Tb02539.X  0.467
1996 Pernambuco MB, Winderickx J, Crauwels M, Griffioen G, Mager WH, Thevelein JM. Glucose-triggered signalling in Saccharomyces cerevisiae: Different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable carbon sources Microbiology. 142: 1775-1782. PMID 8757741  0.413
1996 Pernambuco MB, Winderickx J, Crauwels M, Griffioen G, Mager WH, Thevelein JM. Corrigendum: Glucose-triggered signalling in Saccharomyces cerevisiae: Different requirements for sugar phosphorylation between cells grown on glucose and those grown on non-fermentable carbon sources (Microbiology (1996) 142 (1775-1782)) Microbiology. 142: 3532.  0.323
1995 Thevelein JM, Hohmann S. Trehalose synthase: guard to the gate of glycolysis in yeast? Trends in Biochemical Sciences. 20: 3-10. PMID 7878741 DOI: 10.1016/S0968-0004(00)88938-0  0.384
1995 Neves MJ, Hohmann S, Bell W, Dumortier F, Luyten K, Ramos J, Cobbaert P, de Koning W, Kaneva Z, Thevelein JM. Control of glucose influx into glycolysis and pleiotropic effects studied in different isogenic sets of Saccharomyces cerevisiae mutants in trehalose biosynthesis Current Genetics. 27: 110-122. PMID 7788713 DOI: 10.1007/BF00313424  0.38
1995 Luyten K, Albertyn J, Skibbe WF, Prior BA, Ramos J, Thevelein JM, Hohmann S. Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress Embo Journal. 14: 1360-1371. PMID 7729414  0.328
1995 Dumortier F, Argüelles JC, Thevelein JM. Constitutive glucose-induced activation of the Ras-cAMP pathway and aberrant stationary-phase entry on a glucose-containing medium in the Saccharomyces cerevisiae glucose-repression mutant hex2. Microbiology (Reading, England). 141: 1559-66. PMID 7551024  0.377
1995 Colombo S, Vandijck P, Winderickx J, Hohmann S, Thevelein J. Control of the ras-adenylate cyclase pathway in the yeast saccharomyces-cerevisiae by the ggs1/tps1 gene-product Journal of Cellular Biochemistry. 335-335. DOI: 10.1002/Jcb.240591010  0.323
1994 Luyten K, Albertyn J, Skibbe F, Prior BA, Ramos J, Thevelein JM, Hohmann S. The FPS1 gene product functions as a glycerol facilitator in the yeast Saccharomyces cerevisiae Folia Microbiologica: Official Journal of the Institute of Microbiology, Academy of Sciences of the Czech Republic. 39: 534-536. PMID 8550015 DOI: 10.1007/BF02814092  0.306
1994 Albertyn J, Hohmann S, Thevelein JM, Prior BA. GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway Molecular and Cellular Biology. 14: 4135-4144. PMID 8196651 DOI: 10.1128/Mcb.14.6.4135  0.422
1994 Brandão RL, de Magalhães-Rocha NM, Alijo R, Ramos J, Thevelein JM. Possible involvement of a phosphatidylinositol-type signaling pathway in glucose-induced activation of plasma membrane H+-ATPase and cellular proton extrusion in the yeast Saccharomyces cerevisiae Bba - Molecular Cell Research. 1223: 117-124. PMID 8061044 DOI: 10.1016/0167-4889(94)90080-9  0.333
1994 Durnez P, Pernambuco MB, Oris E, Argüelles JC, Mergelsberg H, Thevelein JM. Activation of trehalase during growth induction by nitrogen sources in the yeast Saccharomyces cerevisiae depends on the free catalytic subunits of cAMP-dependent protein kinase, but not on functional Ras proteins. Yeast (Chichester, England). 10: 1049-64. PMID 7992505 DOI: 10.1002/yea.320100807  0.38
1993 Hohmann S, Neves MJ, de Koning W, Alijo R, Ramos J, Thevelein JM. The growth and signalling defects of the ggs1 (fdp1/byp1) deletion mutant on glucose are suppressed by a deletion of the gene encoding hexokinase PII. Current Genetics. 23: 281-9. PMID 8467527 DOI: 10.1007/BF00310888  0.423
1993 Luyten K, de Koning W, Tesseur I, Ruiz MC, Ramos J, Cobbaert P, Thevelein JM, Hohmann S. Disruption of the Kluyveromyces lactis GGS1 gene causes inability to grow on glucose and fructose and is suppressed by mutations that reduce sugar uptake. European Journal of Biochemistry / Febs. 217: 701-13. PMID 8223613 DOI: 10.1111/J.1432-1033.1993.Tb18296.X  0.49
1993 Hirimburegama K, Durnez P, Keleman J, Oris E, Vergauwen R, Mergelsberg H, Thevelein JM. Nutrient-induced activation of trehalase in nutrient-starved cells of the yeast Saccharomyces cerevisiae: cAMP is not involved as second messenger. Journal of General Microbiology. 138: 2035-43. PMID 1336029 DOI: 10.1099/00221287-138-10-2035  0.37
1992 Hohmann S, Huse K, Valentin E, Mbonyi K, Thevelein J, Zimmermann F. Glucose-induced regulatory defects in the Saccharomyces cerevisiae byp1 growth initiation mutant and identification of MIG1 as a partial suppressor. Journal of Bacteriology. 174: 4183-4188. PMID 1597433 DOI: 10.1128/Jb.174.12.4183-4188.1992  0.451
1992 Thevelein JM. The RAS-adenylate cyclase pathway and cell cycle control in Saccharomyces cerevisiae. Antonie Van Leeuwenhoek. 62: 109-30. PMID 1444331 DOI: 10.1007/BF00584466  0.303
1992 Brandão RL, Castro IM, Passos JB, Nicoli JR, Thevelein JM. Glucose-induced activation of the plasma membrane H(+)-ATPase in Fusarium oxysporum. Journal of General Microbiology. 1579-86. PMID 1326595 DOI: 10.1099/00221287-138-8-1579  0.365
1992 dos Passos JB, Vanhalewyn M, Brandão RL, Castro IM, Nicoli JR, Thevelein JM. Glucose-induced activation of plasma membrane H(+)-ATPase in mutants of the yeast Saccharomyces cerevisiae affected in cAMP metabolism, cAMP-dependent protein phosphorylation and the initiation of glycolysis. Biochimica Et Biophysica Acta. 1136: 57-67. PMID 1322708 DOI: 10.1016/0167-4889(92)90085-P  0.396
1991 van Aelst L, Jans AW, Thevelein JM. Involvement of the CDC25 gene product in the signal transmission pathway of the glucose-induced RAS-mediated cAMP signal in the yeast Saccharomyces cerevisiae. Journal of General Microbiology. 137: 341-9. PMID 1849965 DOI: 10.1099/00221287-137-2-341  0.391
1991 Thevelein J. Fermentable sugars and intracellular acidification as specific activators of the RAS-adenylate cyclase signalling pathway in yeast: the relationship to nutrient-induced cell cycle control. Molecular Microbiology. 5: 1301-1307. PMID 1664904 DOI: 10.1111/J.1365-2958.1991.Tb00776.X  0.474
1990 Mbonyi K, van Aelst L, Argüelles JC, Jans AW, Thevelein JM. Glucose-induced hyperaccumulation of cyclic AMP and defective glucose repression in yeast strains with reduced activity of cyclic AMP-dependent protein kinase. Molecular and Cellular Biology. 10: 4518-23. PMID 2201893  0.407
1990 Van Aelst L, Boy-Marcotte E, Camonis JH, Thevelein JM, Jacquet M. The C-terminal part of the CDC25 gene product plays a key role in signal transduction in the glucose-induced modulation of cAMP level in Saccharomyces cerevisiae. European Journal of Biochemistry / Febs. 193: 675-80. PMID 2174363 DOI: 10.1111/J.1432-1033.1990.TB19386.X  0.37
1990 Argüelles JC, Mbonyi K, Van Aelst L, Vanhalewyn M, Jans AW, Thevelein JM. Absence of glucose-induced cAMP signaling in the Saccharomyces cerevisiae mutants cat1 and cat3 which are deficient in derepression of glucose-repressible proteins. Archives of Microbiology. 154: 199-205. PMID 2169717 DOI: 10.1007/BF00423333  0.363
1990 Beullens M, Thevelein JM. Investigation of transport-associated phosphorylation of sugar in yeast mutants (snf3) lacking high-affinity glucose transport and in a mutant (fdp1) showing deficient regulation of initial sugar metabolism Current Microbiology. 21: 39-46. DOI: 10.1007/BF02090098  0.307
1988 Mbonyi K, Beullens M, Detremerie K, Geerts L, Thevelein J. Requirement of one functional RAS gene and inability of an oncogenic ras variant to mediate the glucose-induced cyclic AMP signal in the yeast Saccharomyces cerevisiae. Molecular and Cellular Biology. 8: 3051-3057. PMID 2850478 DOI: 10.1128/Mcb.8.8.3051  0.418
1988 Beullens M, Mbonyi K, Geerts L, Gladines D, Detremerie K, Jans AW, Thevelein JM. Studies on the mechanism of the glucose-induced cAMP signal in glycolysis and glucose repression mutants of the yeast Saccharomyces cerevisiae. European Journal of Biochemistry. 172: 227-31. PMID 2831059 DOI: 10.1111/j.1432-1033.1988.tb13877.x  0.387
1988 Mbonyi K, Thevelein JM. The high-affinity glucose uptake system is not required for induction of the RAS-mediated cAMP signal by glucose in cells of the yeast Saccharomyces cerevisiae Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 971: 223-226. DOI: 10.1016/S0005-2728(88)80110-5  0.334
1987 Thevelein JM, Beullens M, Honshoven F, Hoebeeck G, Detremerie K, Griewel B, den Hollander JA, Jans AW. Regulation of the cAMP level in the yeast Saccharomyces cerevisiae: the glucose-induced cAMP signal is not mediated by a transient drop in the intracellular pH. Journal of General Microbiology. 133: 2197-205. PMID 2832519 DOI: 10.1099/00221287-133-8-2197  0.648
1987 Thevelein JM, Beullens M, Honshoven F, Hoebeeck G, Detremerie K, den Hollander JA, Jans AW. Regulation of the cAMP level in the yeast Saccharomyces cerevisiae: intracellular pH and the effect of membrane depolarizing compounds. Journal of General Microbiology. 133: 2191-6. PMID 2832518 DOI: 10.1099/00221287-133-8-2191  0.589
1986 Thevelein JM, Beullens M. Cyclic AMP and the stimulation of trehalase activity in the yeast Saccharomyces cerevisiae by carbon sources, nitrogen sources and inhibitors of protein synthesis. Journal of General Microbiology. 131: 3199-209. PMID 3007655 DOI: 10.1099/00221287-131-12-3199  0.369
1984 Thevelein J. Activation of trehalase by membrane-depolarizing agents in yeast vegetative cells and ascospores. Journal of Bacteriology. 158: 337-339. PMID 6370962 DOI: 10.1128/Jb.158.1.337-339.1984  0.371
1984 Thevelein JM. Cyclic-AMP content and trehalase activation in vegetative cells and ascospores of yeast. Archives of Microbiology. 138: 64-7. PMID 6331333 DOI: 10.1007/BF00425409  0.369
1984 Thevelein JM, den Hollander JA, Shulman RG. Trehalase and the control of dormancy and induction of germination in fungal spores Trends in Biochemical Sciences. 9: 495-497. DOI: 10.1016/0968-0004(84)90321-9  0.631
1983 Thevelein JM, Jones KA. Reversibility characteristics of glucose-induced trehalase activation associated with the breaking of dormancy in yeast ascospores European Journal of Biochemistry. 136: 583-587. PMID 6641730 DOI: 10.1111/J.1432-1033.1983.Tb07780.X  0.576
1983 Thevelein JM, Van Laere AJ, Beullens M, Van Assche JA, Carlier AR. Glucose-induced Trehalase Activation and Trehalose Mobilization during Early Germination of Phycomyces blakesleeanus Spores Microbiology. 129: 719-726. DOI: 10.1099/00221287-129-3-719  0.32
1982 Thevelein JM, den Hollander JA, Shulman RG. Changes in the activity and properties of trehalase during early germination of yeast ascospores: correlation with trehalose breakdown as studied by in vivo 13C NMR. Proceedings of the National Academy of Sciences of the United States of America. 79: 3503-7. PMID 6954495 DOI: 10.1073/Pnas.79.11.3503  0.664
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