Michael V. Sefton - Publications

Affiliations: 
Chemical Engineering and Applied Chemistry University of Toronto, Toronto, ON, Canada 
Area:
biomaterials, biomedical engineering and regenerative medicine
Website:
http://seftonlab.utoronto.ca/aboutsefton.html

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kinney SM, Ortaleza K, Vlahos AE, Sefton MV. Degradable methacrylic acid-based synthetic hydrogel for subcutaneous islet transplantation. Biomaterials. 281: 121342. PMID 34995903 DOI: 10.1016/j.biomaterials.2021.121342  0.791
2020 Vlahos AE, Talior-Volodarsky I, Kinney SM, Sefton MV. A scalable device-less biomaterial approach for subcutaneous islet transplantation. Biomaterials. 120499. PMID 33168223 DOI: 10.1016/j.biomaterials.2020.120499  0.795
2020 Coindre VF, Kinney SM, Sefton MV. Methacrylic acid copolymer coating of polypropylene mesh chamber improves subcutaneous islet engraftment. Biomaterials. 259: 120324. PMID 32858417 DOI: 10.1016/J.Biomaterials.2020.120324  0.374
2019 Storer MA, Mahmud N, Karamboulas K, Borrett MJ, Yuzwa SA, Gont A, Androschuk A, Sefton MV, Kaplan DR, Miller FD. Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration. Developmental Cell. PMID 31902657 DOI: 10.1016/J.Devcel.2019.12.004  0.331
2019 Vlahos AE, Kinney SM, Kingston BR, Keshavjee S, Won SY, Martyts A, Chan WWC, Sefton MV. Endothelialized collagen based pseudo-islets enables tuneable subcutaneous diabetes therapy. Biomaterials. 232: 119710. PMID 31901691 DOI: 10.1016/J.Biomaterials.2019.119710  0.803
2019 Coindre VF, Carleton MM, Sefton MV. Methacrylic Acid Copolymer Coating Enhances Constructive Remodeling of Polypropylene Mesh by Increasing the Vascular Response. Advanced Healthcare Materials. e1900667. PMID 31407481 DOI: 10.1002/Adhm.201900667  0.342
2019 Gorbet M, Sperling C, Maitz MF, Siedlecki CA, Werner C, Sefton MV. The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells. Acta Biomaterialia. PMID 31226478 DOI: 10.1016/J.Actbio.2019.06.020  0.689
2018 Mahou R, Vlahos AE, Shulman A, Sefton MV. Interpenetrating Alginate-Collagen Polymer Network Microspheres for Modular Tissue Engineering. Acs Biomaterials Science & Engineering. 4: 3704-3712. PMID 33429609 DOI: 10.1021/Acsbiomaterials.7B00356  0.812
2018 Vlahos AE, Sefton MV. Muted fibrosis from protected islets. Nature Biomedical Engineering. 2: 791-792. PMID 31015616 DOI: 10.1038/S41551-018-0316-9  0.766
2018 Lam GC, Sefton MV. Hypoxia-inducible factor drives vascularization of modularly assembled engineered tissue. Tissue Engineering. Part A. PMID 30585759 DOI: 10.1089/Ten.Tea.2018.0294  0.423
2018 West MED, Sefton EJB, Sefton MV. Bone marrow-derived macrophages enhance vessel stability in modular engineered tissues. Tissue Engineering. Part A. PMID 30351235 DOI: 10.1089/Ten.Tea.2018.0222  0.326
2017 Talior-Volodarsky I, Mahou R, Zhang D, Sefton M. The role of insulin growth factor-1 on the vascular regenerative effect of MAA coated disks and macrophage-endothelial cell crosstalk. Biomaterials. 144: 199-210. PMID 28841464 DOI: 10.1016/J.Biomaterials.2017.08.019  0.374
2017 Vlahos AE, Cober N, Sefton MV. Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets. Proceedings of the National Academy of Sciences of the United States of America. PMID 28814629 DOI: 10.1073/Pnas.1619216114  0.789
2017 Mahou R, Zhang DK, Vlahos AE, Sefton MV. Injectable and inherently vascularizing semi-interpenetrating polymer network for delivering cells to the subcutaneous space. Biomaterials. 131: 27-35. PMID 28371625 DOI: 10.1016/J.Biomaterials.2017.03.032  0.806
2016 Wells LA, Guo H, Emili A, Sefton MV. The profile of adsorbed plasma and serum proteins on methacrylic acid copolymer beads: Effect on complement activation. Biomaterials. 118: 74-83. PMID 27940384 DOI: 10.1016/J.Biomaterials.2016.11.036  0.312
2016 Lisovsky A, Sefton MV. Shh pathway in wounds in non-diabetic Shh-Cre-eGFP/Ptch1-LacZ mice treated with MAA beads. Biomaterials. 102: 198-208. PMID 27343467 DOI: 10.1016/J.Biomaterials.2016.06.027  0.345
2016 Lam GC, Sefton MV. Harnessing gene and drug delivery for vascularizing engineered tissue platforms. Drug Discovery Today. PMID 27319292 DOI: 10.1016/J.Drudis.2016.06.002  0.369
2016 Lisovsky A, Zhang DK, Sefton MV. Effect of methacrylic acid beads on the sonic hedgehog signaling pathway and macrophage polarization in a subcutaneous injection mouse model. Biomaterials. 98: 203-214. PMID 27264502 DOI: 10.1016/J.Biomaterials.2016.04.033  0.354
2016 Zhang B, Montgomery M, Chamberlain MD, Ogawa S, Korolj A, Pahnke A, Wells LA, Massé S, Kim J, Reis L, Momen A, Nunes SS, Wheeler AR, Nanthakumar K, Keller G, ... Sefton MV, et al. Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis. Nature Materials. PMID 26950595 DOI: 10.1038/Nmat4570  0.433
2015 Chamberlain MD, Wells LA, Lisovsky A, Guo H, Isserlin R, Talior-Volodarsky I, Mahou R, Emili A, Sefton MV. Unbiased phosphoproteomic method identifies the initial effects of a methacrylic acid copolymer on macrophages. Proceedings of the National Academy of Sciences of the United States of America. 112: 10673-8. PMID 26261332 DOI: 10.1073/Pnas.1508826112  0.331
2015 Lisovsky A, Chamberlain MD, Wells LA, Sefton MV. Cell Interactions with Vascular Regenerative MAA-Based Materials in the Context of Wound Healing. Advanced Healthcare Materials. PMID 26010569 DOI: 10.1002/Adhm.201500192  0.407
2015 Dean Chamberlain M, West ME, Lam GC, Sefton MV. Commentary on: "In Vivo Remodelling of Vascularizing Engineered Tissues". Annals of Biomedical Engineering. 43: 1271. PMID 25900278 DOI: 10.1007/S10439-015-1322-7  0.326
2015 Kepecs DM, Zhang Y, Thai K, Advani SL, Yuen DA, Connelly KA, Kosanam H, Diamandis E, Sefton MV, Gilbert RE. Application of Modular Therapy for Renoprotection in Experimental Chronic Kidney Disease. Tissue Engineering. Part A. 21: 1963-72. PMID 25661544 DOI: 10.1089/Ten.Tea.2014.0017  0.382
2015 Lam GC, Sefton MV. Tuning graft- and host-derived vascularization in modular tissue constructs: a potential role of HIF1 activation. Tissue Engineering. Part A. 21: 803-16. PMID 25379774 DOI: 10.1089/ten.tea.2014.0315  0.308
2015 Chamberlain MD, West ME, Lam GC, Sefton MV. In vivo remodelling of vascularizing engineered tissues. Annals of Biomedical Engineering. 43: 1189-200. PMID 25297985 DOI: 10.1007/S10439-014-1146-X  0.399
2015 Khan OF, Voice DN, Leung BM, Sefton MV. A novel high-speed production process to create modular components for the bottom-up assembly of large-scale tissue-engineered constructs. Advanced Healthcare Materials. 4: 113-20. PMID 24895070 DOI: 10.1002/Adhm.201400150  0.413
2014 Wells LA, Sefton MV. The effect of methacrylic acid in smooth coatings on dTHP1 and HUVEC gene expression. Biomaterials Science. 2: 1768-1778. PMID 32481955 DOI: 10.1039/C4Bm00159A  0.385
2014 Elliott Donaghue I, Tam R, Sefton MV, Shoichet MS. Cell and biomolecule delivery for tissue repair and regeneration in the central nervous system. Journal of Controlled Release : Official Journal of the Controlled Release Society. 190: 219-27. PMID 24878181 DOI: 10.1016/J.Jconrel.2014.05.040  0.397
2014 Ciucurel EC, Sefton MV. Del-1 overexpression in endothelial cells increases vascular density in tissue-engineered implants containing endothelial cells and adipose-derived mesenchymal stromal cells. Tissue Engineering. Part A. 20: 1235-52. PMID 24151812 DOI: 10.1089/Ten.Tea.2013.0242  0.446
2014 Ciucurel EC, Vlahos AE, Sefton MV. Using Del-1 to tip the angiogenic balance in endothelial cells in modular constructs. Tissue Engineering. Part A. 20: 1222-34. PMID 24138448 DOI: 10.1089/Ten.Tea.2013.0241  0.815
2013 Portalska KJ, Chamberlain MD, Lo C, van Blitterswijk C, Sefton MV, de Boer J. Collagen modules for in situ delivery of mesenchymal stromal cell-derived endothelial cells for improved angiogenesis. Journal of Tissue Engineering and Regenerative Medicine. PMID 23592688 DOI: 10.1002/Term.1738  0.432
2013 Leung BM, Miyagi Y, Li RK, Sefton MV. Fate of modular cardiac tissue constructs in a syngeneic rat model. Journal of Tissue Engineering and Regenerative Medicine. PMID 23505249 DOI: 10.1002/Term.1724  0.39
2013 Wells LA, Valic MS, Lisovsky A, Sefton MV. Angiogenic biomaterials to promote tissue vascularization and integration Israel Journal of Chemistry. 53: 637-645. DOI: 10.1002/Ijch.201300053  0.407
2012 Butler MJ, Sefton MV. Cotransplantation of adipose-derived mesenchymal stromal cells and endothelial cells in a modular construct drives vascularization in SCID/bg mice. Tissue Engineering. Part A. 18: 1628-41. PMID 22655687 DOI: 10.1089/Ten.Tea.2011.0467  0.426
2012 Patel RJ, Sefton MV. Some aspects of the host response to methacrylic acid containing beads in a mouse air pouch. Journal of Biomedical Materials Research. Part A. 100: 2054-62. PMID 22581679 DOI: 10.1002/Jbm.A.34101  0.325
2012 Fitzpatrick LE, Lisovsky A, Sefton MV. The expression of sonic hedgehog in diabetic wounds following treatment with poly(methacrylic acid-co-methyl methacrylate) beads. Biomaterials. 33: 5297-307. PMID 22541537 DOI: 10.1016/J.Biomaterials.2012.04.008  0.751
2012 Holladay CA, Duffy AM, Chen X, Sefton MV, O'Brien TD, Pandit AS. Recovery of cardiac function mediated by MSC and interleukin-10 plasmid functionalised scaffold. Biomaterials. 33: 1303-14. PMID 22078809 DOI: 10.1016/J.Biomaterials.2011.10.019  0.327
2012 Khan OF, Chamberlain MD, Sefton MV. Toward an in vitro vasculature: differentiation of mesenchymal stromal cells within an endothelial cell-seeded modular construct in a microfluidic flow chamber. Tissue Engineering. Part A. 18: 744-56. PMID 21992078 DOI: 10.1089/Ten.Tea.2011.0058  0.402
2012 Chamberlain MD, Gupta R, Sefton MV. Bone marrow-derived mesenchymal stromal cells enhance chimeric vessel development driven by endothelial cell-coated microtissues. Tissue Engineering. Part A. 18: 285-94. PMID 21861779 DOI: 10.1089/Ten.Tea.2011.0393  0.445
2011 Fitzpatrick LE, Chan JW, Sefton MV. On the mechanism of poly(methacrylic acid -co- methyl methacrylate)-induced angiogenesis: gene expression analysis of dTHP-1 cells. Biomaterials. 32: 8957-67. PMID 21872324 DOI: 10.1016/J.Biomaterials.2011.08.021  0.759
2011 Khan OF, Sefton MV. Endothelialized biomaterials for tissue engineering applications in vivo. Trends in Biotechnology. 29: 379-87. PMID 21549438 DOI: 10.1016/J.Tibtech.2011.03.004  0.442
2011 Gupta R, Sefton MV. Application of an endothelialized modular construct for islet transplantation in syngeneic and allogeneic immunosuppressed rat models. Tissue Engineering. Part A. 17: 2005-15. PMID 21449709 DOI: 10.1089/Ten.Tea.2010.0542  0.404
2011 Holladay C, Power K, Sefton M, O'Brien T, Gallagher WM, Pandit A. Functionalized scaffold-mediated interleukin 10 gene delivery significantly improves survival rates of stem cells in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 969-78. PMID 21266957 DOI: 10.1038/Mt.2010.311  0.351
2011 Ciucurel EC, Sefton MV. A Poloxamine-Polylysine Acrylate Scaffold for Modular Tissue Engineering. Journal of Biomaterials Science. Polymer Edition. 22: 2515-28. PMID 21144169 DOI: 10.1163/092050610X541133  0.363
2011 Khan OF, Sefton MV. Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications. Journal of Biomaterials Science. Polymer Edition. 22: 2499-514. PMID 21144168 DOI: 10.1163/092050610X540693  0.418
2011 Cooper TP, Sefton MV. Fibronectin coating of collagen modules increases in vivo HUVEC survival and vessel formation in SCID mice. Acta Biomaterialia. 7: 1072-83. PMID 21059413 DOI: 10.1016/J.Actbio.2010.11.008  0.42
2011 Khan OF, Sefton MV. Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct. Biomedical Microdevices. 13: 69-87. PMID 20842530 DOI: 10.1007/S10544-010-9472-8  0.349
2011 Chamberlain MD, Gupta R, Sefton MV. Chimeric vessel tissue engineering driven by endothelialized modules in immunosuppressed Sprague-Dawley rats. Tissue Engineering. Part A. 17: 151-60. PMID 20695789 DOI: 10.1089/Ten.Tea.2010.0293  0.405
2011 Corstorphine L, Sefton MV. Effectiveness factor and diffusion limitations in collagen gel modules containing HepG2 cells. Journal of Tissue Engineering and Regenerative Medicine. 5: 119-29. PMID 20653045 DOI: 10.1002/Term.296  0.372
2010 Chamberlain MD, Butler MJ, Ciucurel EC, Fitzpatrick LE, Khan OF, Leung BM, Lo C, Patel R, Velchinskaya A, Voice DN, Sefton MV. Fabrication of micro-tissues using modules of collagen gel containing cells. Journal of Visualized Experiments : Jove. PMID 21178971 DOI: 10.3791/2177  0.776
2010 Khan OF, Sefton MV. Perfusion and characterization of an endothelial cell-seeded modular tissue engineered construct formed in a microfluidic remodeling chamber. Biomaterials. 31: 8254-61. PMID 20678792 DOI: 10.1016/J.Biomaterials.2010.07.041  0.407
2010 Leung BM, Sefton MV. A modular approach to cardiac tissue engineering. Tissue Engineering. Part A. 16: 3207-18. PMID 20504074 DOI: 10.1089/Ten.Tea.2009.0746  0.373
2010 Khan OF, Jean-Francois J, Sefton MV. MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo. Journal of Biomedical Materials Research. Part A. 93: 1368-79. PMID 19911383 DOI: 10.1002/Jbm.A.32634  0.333
2010 Martin DC, Semple JL, Sefton MV. Poly(methacrylic acid-co-methyl methacrylate) beads promote vascularization and wound repair in diabetic mice. Journal of Biomedical Materials Research. Part A. 93: 484-92. PMID 19585566 DOI: 10.1002/Jbm.A.32528  0.356
2009 Ailenberg M, Sefton MV. Effect of a matrix metalloproteinase sequestering biomaterial on Caco-2 epithelial cell barrier integrity in vitro. Acta Biomaterialia. 5: 1898-904. PMID 19307161 DOI: 10.1016/J.Actbio.2009.02.028  0.329
2009 Gupta R, Van Rooijen N, Sefton MV. Fate of endothelialized modular constructs implanted in an omental pouch in nude rats. Tissue Engineering. Part A. 15: 2875-87. PMID 19265460 DOI: 10.1089/Ten.Tea.2008.0494  0.441
2009 Cheng D, Sefton MV. Dual delivery of placental growth factor and vascular endothelial growth factor from poly(hydroxyethyl methacrylate-co-methyl methacrylate) microcapsules containing doubly transfected luciferase-expressing L929 cells. Tissue Engineering. Part A. 15: 1929-39. PMID 19125649 DOI: 10.1089/Ten.Tea.2008.0470  0.38
2009 Van Slyke P, Alami J, Martin D, Kuliszewski M, Leong-Poi H, Sefton MV, Dumont D. Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue Engineering. Part A. 15: 1269-80. PMID 18939935 DOI: 10.1089/Ten.Tea.2007.0400  0.351
2009 Surzyn M, Symes J, Medin JA, Sefton MV. IL-10 secretion increases signal persistence of HEMA-MMA-microencapsulated luciferase-modified CHO fibroblasts in mice. Tissue Engineering. Part A. 15: 127-36. PMID 18710337 DOI: 10.1089/Ten.Tea.2008.0028  0.407
2009 Yim EK, Sefton MV. Amidine surface modification of poly(acrylonitrile-co-vinyl chloride) reduces platelet adhesion. Journal of Biomedical Materials Research. Part A. 89: 780-90. PMID 18465816 DOI: 10.1002/Jbm.A.32022  0.326
2008 Eckhaus AA, Fish JS, Skarja G, Semple JL, Sefton MV. A preliminary study of the effect of poly(methacrylic acid-co-methyl methacrylate) beads on angiogenesis in rodent skin grafts and the quality of the panniculus carnosus. Plastic and Reconstructive Surgery. 122: 1361-70. PMID 18971719 DOI: 10.1097/Prs.0B013E3181882082  0.352
2008 McGuigan AP, Sefton MV. The thrombogenicity of human umbilical vein endothelial cell seeded collagen modules. Biomaterials. 29: 2453-63. PMID 18325586 DOI: 10.1016/J.Biomaterials.2008.02.010  0.704
2008 Sefton MV, Babensee JE, Woodhouse KA. Innate and adaptive immune responses in tissue engineering. Seminars in Immunology. 20: 83-5. PMID 18221888 DOI: 10.1016/J.Smim.2007.12.008  0.718
2008 Cheng D, Lo C, Sefton MV. Effect of mouse VEGF164 on the viability of hydroxyethyl methacrylate-methyl methacrylate-microencapsulated cells in vivo: bioluminescence imaging. Journal of Biomedical Materials Research. Part A. 87: 321-31. PMID 18181105 DOI: 10.1002/Jbm.A.31716  0.416
2008 Sosnik A, Leung BM, Sefton MV. Lactoyl-poloxamine/collagen matrix for cell-containing tissue engineering modules. Journal of Biomedical Materials Research. Part A. 86: 339-53. PMID 17969022 DOI: 10.1002/Jbm.A.31594  0.453
2007 McGuigan AP, Sefton MV. Modular tissue engineering: fabrication of a gelatin-based construct. Journal of Tissue Engineering and Regenerative Medicine. 1: 136-45. PMID 18038402 DOI: 10.1002/Term.14  0.702
2007 Leung BM, Sefton MV. A modular tissue engineering construct containing smooth muscle cells and endothelial cells. Annals of Biomedical Engineering. 35: 2039-49. PMID 17882548 DOI: 10.1007/S10439-007-9380-0  0.363
2007 McGuigan AP, Sefton MV. Design and fabrication of sub-mm-sized modules containing encapsulated cells for modular tissue engineering. Tissue Engineering. 13: 1069-78. PMID 17582838 DOI: 10.1089/Ten.2006.0253  0.701
2007 Butler MJ, Sefton MV. Poly(butyl methacrylate-co-methacrylic acid) tissue engineering scaffold with pro-angiogenic potential in vivo. Journal of Biomedical Materials Research. Part A. 82: 265-73. PMID 17530634 DOI: 10.1002/Jbm.A.31314  0.398
2007 Vallbacka JJ, Sefton MV. Vascularization and improved in vivo survival of VEGF-secreting cells microencapsulated in HEMA-MMA. Tissue Engineering. 13: 2259-69. PMID 17523877 DOI: 10.1089/Ten.2006.0284  0.445
2007 McGuigan AP, Sefton MV. Design criteria for a modular tissue-engineered construct. Tissue Engineering. 13: 1079-89. PMID 17439395 DOI: 10.1089/Ten.2006.0245  0.668
2007 McGuigan AP, Sefton MV. The influence of biomaterials on endothelial cell thrombogenicity. Biomaterials. 28: 2547-71. PMID 17316788 DOI: 10.1016/J.Biomaterials.2007.01.039  0.709
2007 She M, McGuigan AP, Sefton MV. Tissue factor and thrombomodulin expression on endothelial cell-seeded collagen modules for tissue engineering. Journal of Biomedical Materials Research. Part A. 80: 497-504. PMID 17111414 DOI: 10.1002/Jbm.A.31083  0.713
2006 Freed LE, Guilak F, Guo XE, Gray ML, Tranquillo R, Holmes JW, Radisic M, Sefton MV, Kaplan D, Vunjak-Novakovic G. Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. Tissue Engineering. 12: 3285-305. PMID 17518670 DOI: 10.1089/Ten.2006.12.3285  0.357
2006 McGuigan AP, Leung B, Sefton MV. Fabrication of cell-containing gel modules to assemble modular tissue-engineered constructs [corrected]. Nature Protocols. 1: 2963-9. PMID 17406556 DOI: 10.1038/Nprot.2006.443  0.677
2006 Jones KS, Sefton MV, Gorczynski RM. Suppressed splenocyte proliferation following a xenogeneic skin graft due to implanted biomaterials. Transplantation. 82: 415-21. PMID 16906042 DOI: 10.1097/01.Tp.0000228917.57323.Ec  0.54
2006 McGuigan AP, Sefton MV. Vascularized organoid engineered by modular assembly enables blood perfusion. Proceedings of the National Academy of Sciences of the United States of America. 103: 11461-6. PMID 16864785 DOI: 10.1073/Pnas.0602740103  0.71
2006 Sosnik A, Sefton MV. Methylation of poloxamine for enhanced cell adhesion. Biomacromolecules. 7: 331-8. PMID 16398533 DOI: 10.1021/Bm050693H  0.393
2006 Sosnik A, Sodhi RN, Brodersen PM, Sefton MV. Surface study of collagen/poloxamine hydrogels by a 'deep freezing' ToF-SIMS approach. Biomaterials. 27: 2340-8. PMID 16332388 DOI: 10.1016/J.Biomaterials.2005.11.028  0.321
2005 Sosnik A, Leung B, McGuigan AP, Sefton MV. Collagen/poloxamine hydrogels: cytocompatibility of embedded HepG2 cells and surface-attached endothelial cells. Tissue Engineering. 11: 1807-16. PMID 16411826 DOI: 10.1089/Ten.2005.11.1807  0.714
2005 Khademhosseini A, May MH, Sefton MV. Conformal coating of mammalian cells immobilized onto magnetically driven beads. Tissue Engineering. 11: 1797-806. PMID 16411825 DOI: 10.1089/Ten.2005.11.1797  0.373
2005 Sosnik A, Sefton MV. Poloxamine hydrogels with a quaternary ammonium modification to improve cell attachment. Journal of Biomedical Materials Research. Part A. 75: 295-307. PMID 16059894 DOI: 10.1002/Jbm.A.30419  0.393
2005 Gorbet MB, Sefton MV. Complement inhibition reduces material-induced leukocyte activation with PEG modified polystyrene beads (Tentagel) but not polystyrene beads. Journal of Biomedical Materials Research. Part A. 74: 511-22. PMID 16035062 DOI: 10.1002/Jbm.A.30354  0.686
2005 Sosnik A, Sefton MV. Semi-synthetic collagen/poloxamine matrices for tissue engineering. Biomaterials. 26: 7425-35. PMID 16023714 DOI: 10.1016/J.Biomaterials.2005.05.086  0.398
2005 Gorbet MB, Sefton MV. Endotoxin: the uninvited guest. Biomaterials. 26: 6811-7. PMID 16019062 DOI: 10.1016/J.Biomaterials.2005.04.063  0.657
2004 Jones KS, Sefton MV, Gorczynski RM. In vivo recognition by the host adaptive immune system of microencapsulated xenogeneic cells. Transplantation. 78: 1454-62. PMID 15599309 DOI: 10.1097/01.Tp.0000142094.63083.Fb  0.538
2004 Gorbet MB, Sefton MV. Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes. Biomaterials. 25: 5681-703. PMID 15147815 DOI: 10.1016/J.Biomaterials.2004.01.023  0.681
2004 Skarja GA, Gorbet MB, Lawson‐Smith RK, May MH, Sefton MV. 006 Development of a Novel Matrix Metalloproteinase?Inhibiting Wound Dressing Wound Repair and Regeneration. 12: A4-A4. DOI: 10.1111/J.1067-1927.2004.0Abstractg.X  0.67
2004 Eckhaus A, Fish J, Sefton M. 065 Improving Integra™“Take” with Negatively Charged Methacrlylic Acid Beads Wound Repair and Regeneration. 12. DOI: 10.1111/J.1067-1927.2004.0Abstractbl.X  0.301
2004 Sefton MV. THE NEW NEW BIOMATERIALS Advances in Chemical Engineering. 29: 1-6. DOI: 10.1016/S0065-2377(03)29001-3  0.348
2004 McGuigan AP, Sefton MV. DESIGN AND FABRICATION OF A VASCULARISED TISSUE-ENGINEERED CONSTRUCT Cardiovascular Pathology. 13: 182. DOI: 10.1016/J.Carpath.2004.03.547  0.638
2003 Gorbet MB, Sefton MV. Material-induced tissue factor expression but not CD11b upregulation depends on the presence of platelets. Journal of Biomedical Materials Research. Part A. 67: 792-800. PMID 14613227 DOI: 10.1002/Jbm.A.10155  0.68
2003 Yamamoto Y, Sefton MV. Reaction of poly(acrylamide-co-vinylamine) with tresyl-PEG in the presence of PC12 cells. Biomaterials. 24: 435-42. PMID 12423598 DOI: 10.1016/S0142-9612(02)00356-3  0.372
2003 Eckhaus AA, Fish JS, Skarja G, Gorbet M, Sefton MV. The Effects of Methacrylic Acid Containing Beads on Angiogenesis in a Rodent Skin Graft Model Journal of Burn Care & Rehabilitation. 24: S46. DOI: 10.1097/00004630-200303002-00007  0.66
2002 Guilak F, Kapur R, Sefton MV, Vandenburgh HH, Koretsky AP, Kriete A, O'Keefe RJ. Functional assessment of engineered tissues and elements of tissue design: breakout session summary. Annals of the New York Academy of Sciences. 961: 207-9. PMID 12081902 DOI: 10.1111/J.1749-6632.2002.Tb03086.X  0.307
2001 Vallbacka JJ, Nobrega JN, Sefton MV. Tissue engineering as a platform for controlled release of therapeutic agents: implantation of microencapsulated dopamine producing cells in the brains of rats. Journal of Controlled Release : Official Journal of the Controlled Release Society. 72: 93-100. PMID 11389988 DOI: 10.1016/S0168-3659(01)00265-6  0.38
2001 Gorbet MB, Sefton MV. Leukocyte activation and leukocyte procoagulant activities after blood contact with polystyrene and polyethylene glycol-immobilized polystyrene beads. The Journal of Laboratory and Clinical Medicine. 137: 345-55. PMID 11329532 DOI: 10.1067/Mlc.2001.114677  0.693
2001 Sefton MV, Sawyer A, Gorbet M, Black JP, Cheng E, Gemmell C, Pottinger-Cooper E. Does surface chemistry affect thrombogenicity of surface modified polymers? Journal of Biomedical Materials Research. 55: 447-59. PMID 11288072 DOI: 10.1002/1097-4636(20010615)55:4<447::Aid-Jbm1036>3.0.Co;2-5  0.688
2000 Sefton MV, Gemmell CH, Gorbet MB. What really is blood compatibility? Journal of Biomaterials Science. Polymer Edition. 11: 1165-82. PMID 11263806 DOI: 10.1163/156856200744255  0.67
2000 Lahooti S, Sefton MV. Agarose enhances the viability of intraperitoneally implanted microencapsulated L929 fibroblasts. Cell Transplantation. 9: 785-96. PMID 11202565 DOI: 10.1177/096368970000900605  0.374
2000 Babensee JE, Sefton MV. Viability of HEMA-MMA microencapsulated model hepatoma cells in rats and the host response. Tissue Engineering. 6: 165-82. PMID 10941211 DOI: 10.1089/107632700320784  0.719
2000 Lahooti S, Sefton MV. Microencapsulation of normal and transfected L929 fibroblasts in a HEMA-MMA copolymer. Tissue Engineering. 6: 139-49. PMID 10941209 DOI: 10.1089/107632700320766  0.386
2000 Feng M, Sefton MV. Hydroxyethyl methacrylate-methyl methacrylate (HEMA-MMA) copolymers for cell microencapsulation: effect of HEMA purity. Journal of Biomaterials Science. Polymer Edition. 11: 537-45. PMID 10896046 DOI: 10.1163/156856200743850  0.36
2000 Lahooti S, Sefton MV. Effect of an immobilization matrix and capsule membrane permeability on the viability of encapsulated HEK cells. Biomaterials. 21: 987-95. PMID 10768750 DOI: 10.1016/S0142-9612(99)00251-3  0.39
2000 Sefton MV, May MH, Lahooti S, Babensee JE. Making microencapsulation work: conformal coating, immobilization gels and in vivo performance. Journal of Controlled Release : Official Journal of the Controlled Release Society. 65: 173-86. PMID 10699279 DOI: 10.1016/S0168-3659(99)00234-5  0.724
1999 Lahooti S, Sefton MV. Methods for Microencapsulation with HEMA-MMA. Methods in Molecular Medicine. 18: 331-48. PMID 21370188 DOI: 10.1385/0-89603-516-6:331  0.342
1999 May MH, Sefton MV. Conformal coating of small particles and cell aggregates at a liquid-liquid interface. Annals of the New York Academy of Sciences. 875: 126-34. PMID 10415562 DOI: 10.1111/J.1749-6632.1999.Tb08498.X  0.337
1999 Gorbet MB, Yeo EL, Sefton MV. Flow cytometric study of in vitro neutrophil activation by biomaterials. Journal of Biomedical Materials Research. 44: 289-97. PMID 10397931 DOI: 10.1002/(Sici)1097-4636(19990305)44:3<289::Aid-Jbm7>3.0.Co;2-O  0.685
1999 Godo MN, Sefton MV. Characterization of transient platelet contacts on a polyvinyl alcohol hydrogel by video microscopy. Biomaterials. 20: 1117-26. PMID 10382827 DOI: 10.1016/S0142-9612(99)00012-5  0.317
1998 Babensee JE, Cornelius RM, Brash JL, Sefton MV. Immunoblot analysis of proteins associated with HEMA-MMA microcapsules: human serum proteins in vitro and rat proteins following implantation. Biomaterials. 19: 839-49. PMID 9663761 DOI: 10.1016/S0142-9612(97)00242-1  0.651
1998 Campioni EG, Nobrega JN, Sefton MV. HEMA/MMMA microcapsule implants in hemiparkinsonian rat brain: biocompatibility assessment using [3H]PK11195 as a marker for gliosis. Biomaterials. 19: 829-37. PMID 9663760 DOI: 10.1016/S0142-9612(97)00241-X  0.321
1998 Yamamoto Y, Sefton MV. Surface grafting of poly(ethylene glycol) onto poly(acrylamide-co-vinyl amine) cross-linked films under mild conditions. Journal of Biomaterials Science. Polymer Edition. 9: 427-37. PMID 9648025 DOI: 10.1163/156856298X00541  0.34
1997 Sefton MV, Hwang JR, Babensee JE. Selected aspects of the microencapsulation of mammalian cells in HEMA-MMA. Annals of the New York Academy of Sciences. 831: 260-70. PMID 9616718 DOI: 10.1111/J.1749-6632.1997.Tb52201.X  0.695
1997 Babensee JE, Sodhi RN, Sefton MV. X-ray photoelectron spectroscopy (XPS) surface analysis of HEMA-MMA microcapsules. Journal of Biomaterials Science. Polymer Edition. 8: 655-65. PMID 9257179 DOI: 10.1163/156856297X00470  0.663
1996 Tse M, Uludag H, Sefton MV, Chang PL. Secretion of recombinant proteins from hydroxyethyl methacrylate-methyl methacrylate capsules. Biotechnology and Bioengineering. 51: 271-80. PMID 18624360 DOI: 10.1002/(Sici)1097-0290(19960805)51:3<271::Aid-Bit3>3.0.Co;2-A  0.376
1996 Gemmell CH, Black JP, Yeo EL, Sefton MV. Material-induced up-regulation of leukocyte CD11b during whole blood contact: material differences and a role for complement. Journal of Biomedical Materials Research. 32: 29-35. PMID 8864870 DOI: 10.1002/(Sici)1097-4636(199609)32:1<29::Aid-Jbm4>3.0.Co;2-R  0.335
1996 Roberts T, De Boni U, Sefton MV. Dopamine secretion by PC12 cells microencapsulated in a hydroxyethyl methacrylate--methyl methacrylate copolymer. Biomaterials. 17: 267-75. PMID 8745323 DOI: 10.1016/0142-9612(96)85564-5  0.397
1996 Babensee JE, Sefton MV. Allogeneic and xenogeneic transplantation of hema-MMA microencapsulated hepatoma cells into rats Cell Transplantation. 5: 56. DOI: 10.1016/0963-6897(96)82245-7  0.302
1995 Hwang JR, Sefton MV. The effects of polymer concentration and a pore-forming agent (PVP) on HEMA-MMA microcapsule structure and permeability Journal of Membrane Science. 108: 257-268. DOI: 10.1016/0376-7388(95)00168-9  0.374
1995 Uludag H, Hwang JR, Sefton MV. Microencapsulated human hepatoma (HepG2) cells: capsule-to-capsule variations in protein secretion and permeability Journal of Controlled Release. 33: 273-283. DOI: 10.1016/0168-3659(94)00094-B  0.308
1994 Uludag H, Horvath V, Black JP, Sefton MV. Viability and protein secretion from human Hepatoma (HepG2) cells encapsulated in 400-mum polyacrylate microcapsules by submerged nozzle-liquid jet extrusion. Biotechnology and Bioengineering. 44: 1199-204. PMID 18618546 DOI: 10.1002/Bit.260441007  0.349
1994 Turner JS, Sefton MV. Immobilization of a lysine-terminated heparin to polyvinyl alcohol. Journal of Biomaterials Science. Polymer Edition. 5: 353-69. PMID 8025031 DOI: 10.1163/156856294X00077  0.311
1994 Sefton MV, Uludag H, Babensee J, Roberts T, Horvath V, Boni UD. 22 – Microencapsulation of Cells in Thermoplastic Copolymer (Hydroxyethyl Methacrylate–Methyl Methacrylate) Methods in Neurosciences. 21: 371-386. DOI: 10.1016/B978-0-12-185291-7.50028-X  0.717
1993 Rollason G, Davies JE, Sefton MV. Preliminary report on cell culture on a thermally reversible copolymer. Biomaterials. 14: 153-5. PMID 8435460 DOI: 10.1016/0142-9612(93)90230-Y  0.358
1993 Llanos GR, Sefton MV. Review Does polyethylene oxide possess a low thrombogenicity Journal of Biomaterials Science-Polymer Edition. 4: 381-400. PMID 8373752 DOI: 10.1163/156856293X00069  0.303
1993 Uludag H, Sefton MV. Microencapsulated human hepatoma (HepG2) cells: in vitro growth and protein release. Journal of Biomedical Materials Research. 27: 1213-24. PMID 8245036 DOI: 10.1002/Jbm.820271002  0.376
1993 Eisa T, Sefton MV. Towards the preparation of a MMA-PEO block copolymer for the microencapsulation of mammalian cells. Biomaterials. 14: 755-61. PMID 8218725 DOI: 10.1016/0142-9612(93)90040-9  0.337
1993 Uludag H, Sefton MV. Metabolic activity and proliferation of CHO cells in hydroxyethyl methacrylate-methyl methacrylate (HEMA-MMA) microcapsules Cell Transplantation. 2: 175-182. PMID 8143082 DOI: 10.1177/096368979300200210  0.359
1993 Uludag H, Kharlip L, Sefton MV. Protein delivery by microencapsulated cells Advanced Drug Delivery Reviews. 10: 115-130. DOI: 10.1016/0169-409X(93)90006-P  0.358
1993 Uludag H, Babensee JE, Roberts T, Kharlip L, Horvath V, Sefton MV. Controlled release of dopamine, insulin and other agents from microencapsulated cells Journal of Controlled Release. 24: 3-11. DOI: 10.1016/0168-3659(93)90164-Z  0.697
1992 Uludag H, Sefton MV. Metabolic activity of CHO fibroblasts in HEMA-MMA microcapsules. Biotechnology and Bioengineering. 39: 672-678. PMID 18600997 DOI: 10.1002/Bit.260390612  0.323
1992 Llanos GR, Sefton MV. Heparin-poly(ethylene glycol)-poly(vinyl alcohol) hydrogel: preparation and assessment of thrombogenicity. Biomaterials. 13: 421-424. PMID 1633215 DOI: 10.1016/0142-9612(92)90161-G  0.343
1992 Babensee JE, De Boni U, Sefton MV. Morphological assessment of hepatoma cells (HepG2) microencapsulated in a HEMA-MMA copolymer with and without Matrigel. Journal of Biomedical Materials Research. 26: 1401-18. PMID 1332972 DOI: 10.1002/Jbm.820261102  0.706
1992 Sefton MV, Kharlip L, Horvath V, Roberts T. Controlled release using microencapsulated mammalian cells Journal of Controlled Release. 19: 289-297. DOI: 10.1016/0168-3659(92)90084-5  0.395
1990 Douglas JA, Sefton MV. The permeability of EUDRAGIT RL and HEMA-MMA microcapsules to glucose and inulin. Biotechnology and Bioengineering. 36: 653-664. PMID 18597256 DOI: 10.1002/Bit.260360702  0.314
1990 Crooks CA, Douglas JA, Broughton RL, Sefton MV. Microencapsulation of mammalian cells in a HEMA-MMA copolymer: Effects on capsule morphology and permeability Journal of Biomedical Materials Research. 24: 1241-1262. PMID 2211747 DOI: 10.1002/Jbm.820240908  0.332
1990 Uludag H, Sefton MV. Colorimetric assay fop cellular activity in microcapsules Biomaterials. 11: 708-712. PMID 2090308 DOI: 10.1016/0142-9612(90)90032-L  0.372
1989 Mallabone CL, Crooks CA, Sefton MV. Microencapsulation of human diploid fibroblasts in cationic polyacrylates Biomaterials. 10: 380-386. PMID 2804227 DOI: 10.1016/0142-9612(89)90129-4  0.365
1989 Cholakis CH, Zingg W, Sefton MV. Effect of heparin-PVA hydrogel on platelets in a chronic canine arterio-venous shunt. Journal of Biomedical Materials Research. 23: 417-441. PMID 2708416 DOI: 10.1002/Jbm.820230404  0.312
1989 Cholakis CH, Sefton MV. In vitro platelet interactions with a heparin–polyvinyl alcohol hydrogel Journal of Biomedical Materials Research. 23: 399-415. PMID 2708415 DOI: 10.1002/Jbm.820230403  0.324
1989 Broughton RL, Sefton MV. Effect of capsule permeability on growth of CHO cells in Eudragit EL microcapsules: use of FITC-dextran as a marker of capsule quality Biomaterials. 10: 462-465. PMID 2478206 DOI: 10.1016/0142-9612(89)90087-2  0.329
1987 Boag AH, Sefton MV. Microencapsulation of human fibroblasts in a water-insoluble polyacrylate. Biotechnology and Bioengineering. 30: 954-962. PMID 18581534 DOI: 10.1002/Bit.260300806  0.359
1987 Sefton MV, Dawson RM, Broughton RL, Blysniuk J, Sugamori ME. Microencapsulation of mammalian cells in a water-insoluble polyacrylate by coextrustion and interfacial precipitation. Biotechnology and Bioengineering. 29: 1135-43. PMID 18576568 DOI: 10.1002/Bit.260290914  0.342
1987 Dawson RM, Broughton RL, Stevenson WT, Sefton MV. Microencapsulation of CHO cells in a hydroxyethyl methacrylate-methyl methacrylate copolymer. Biomaterials. 8: 360-6. PMID 3676422 DOI: 10.1016/0142-9612(87)90006-8  0.382
1987 Stevenson WTK, Sefton MV. Graft copolymer emulsions of sodium alginate with hydroxyallsyl methacrylates for microencapsulation Biomaterials. 8: 449-457. PMID 3427143 DOI: 10.1016/0142-9612(87)90081-0  0.368
1987 Sefton MV, Broughton RL, Sugamori ME, Mallabone CL. Hydrophilic polyacrylates for the microencapsulation of fibroblasts or pancreatic islets Journal of Controlled Release. 6: 177-187. DOI: 10.1016/0168-3659(87)90075-7  0.42
1986 Allen DG, Sefton MV. A model of insulin delivery by a controlled release micropump. Annals of Biomedical Engineering. 14: 257-76. PMID 3767093 DOI: 10.1007/Bf02584274  0.376
1985 Ip WF, Zingg W, Sefton MV. Parallel flow arteriovenous shunt for the ex vivo evaluation of heparinized materials Journal of Biomedical Materials Research. 19: 161-178. PMID 4077878 DOI: 10.1002/Jbm.820190206  0.304
1984 Sefton MV, Ip WF, Rollason G, Hatton MWC, Zingg W. The Thromboresistance Of A Heparin-Polyvinyl Alcohol Hydrogel† Chemical Engineering Communications. 30: 141-154. DOI: 10.1080/00986448408911123  0.303
1984 Lamberti FV, Evangelista RA, Blysniuk J, Wheatley MA, Sefton MV. Microencapsulation of Mammalian Cells in Polyacrylates Applied Biochemistry and Biotechnology. 10: 101-104. DOI: 10.1007/978-1-4612-5182-8_10  0.312
1983 Lamberti FV, Sefton MV. Microencapsulation of erythrocytes in Eudragit-RL-coated calcium alginate Biochimica Et Biophysica Acta. 759: 81-91. PMID 6882794 DOI: 10.1016/0304-4165(83)90192-7  0.331
1983 Goosen MFA, Sefton MV. Properties of a heparin-poly(vinyl alcohol) hydrogel coating. Journal of Biomedical Materials Research. 17: 359-373. PMID 6841373 DOI: 10.1002/Jbm.820170212  0.34
1982 Sefton MV, Broughton RL. Microencapsulation of erythrocytes Biochimica Et Biophysica Acta. 717: 473-477. PMID 7126642 DOI: 10.1016/0304-4165(82)90290-2  0.325
1980 Goosen MFA, Sefton MV, Hatton MWC. Inactivation of thrombin by antithrombin III on a heparinized biomaterial. Thrombosis Research. 20: 543-554. PMID 7233384 DOI: 10.1016/0049-3848(80)90142-5  0.311
1980 Sefton MV, Lusher HM. Hydraulic permeability of open‐cell hydrophilic polyurethane foams Journal of Applied Polymer Science. 25: 2167-2178. DOI: 10.1002/App.1980.070251003  0.301
1979 Goosen MFA, Sefton MV. Heparinized styrene-butadiene-styrene elastomers. Journal of Biomedical Materials Research. 13: 347-364. PMID 438224 DOI: 10.1002/Jbm.820130302  0.326
1976 Sefton MV, Merrill EW. Surface hydroxylation of styrene-butadiene-styrene block copolymers for biomaterials. Journal of Biomedical Materials Research. 10: 33-45. PMID 1249089 DOI: 10.1002/Jbm.820100105  0.49
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