Don Ganem - Publications

Affiliations: 
2011-2013 Novartis Institute for BioMedical Research 

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hyrina A, Jones C, Chen D, Clarkson S, Cochran N, Feucht P, Hoffman G, Lindeman A, Russ C, Sigoillot F, Tsang T, Uehara K, Xie L, Ganem D, Holdorf M. A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production. Cell Reports. 29: 2970-2978.e6. PMID 31801065 DOI: 10.1016/J.Celrep.2019.10.113  0.444
2015 Tropberger P, Mercier A, Robinson M, Zhong W, Ganem DE, Holdorf M. Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation. Proceedings of the National Academy of Sciences of the United States of America. 112: E5715-24. PMID 26438841 DOI: 10.1073/Pnas.1518090112  0.336
2015 Bellare P, Dufresne A, Ganem D. Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus. Journal of Virology. 89: 7097-107. PMID 25926644 DOI: 10.1128/Jvi.03390-14  0.478
2014 Mercier A, Arias C, Madrid AS, Holdorf MM, Ganem D. Site-specific association with host and viral chromatin by Kaposi's sarcoma-associated herpesvirus LANA and its reversal during lytic reactivation. Journal of Virology. 88: 6762-77. PMID 24696474 DOI: 10.1128/Jvi.00268-14  0.783
2014 Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D. KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features. Plos Pathogens. 10: e1003847. PMID 24453964 DOI: 10.1371/Journal.Ppat.1003847  0.771
2013 Chang HH, Ganem D. A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity. Cell Host & Microbe. 13: 429-40. PMID 23601105 DOI: 10.1016/J.Chom.2013.03.009  0.432
2013 Chandriani S, Skewes-Cox P, Zhong W, Ganem DE, Divers TJ, Van Blaricum AJ, Tennant BC, Kistler AL. Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1407-15. PMID 23509292 DOI: 10.1073/Pnas.1219217110  0.305
2012 Lee D, Das Gupta J, Gaughan C, Steffen I, Tang N, Luk KC, Qiu X, Urisman A, Fischer N, Molinaro R, Broz M, Schochetman G, Klein EA, Ganem D, Derisi JL, et al. In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer. Plos One. 7: e44954. PMID 23028701 DOI: 10.1371/Journal.Pone.0044954  0.333
2012 Stenglein MD, Velazquez E, Greenacre C, Wilkes RP, Ruby JG, Lankton JS, Ganem D, Kennedy MA, DeRisi JL. Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis. Virology Journal. 9: 216. PMID 22998755 DOI: 10.1186/1743-422X-9-216  0.42
2012 Brulois KF, Chang H, Lee AS, Ensser A, Wong LY, Toth Z, Lee SH, Lee HR, Myoung J, Ganem D, Oh TK, Kim JF, Gao SJ, Jung JU. Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone. Journal of Virology. 86: 9708-20. PMID 22740391 DOI: 10.1128/Jvi.01019-12  0.428
2012 Madrid AS, Ganem D. Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44. Journal of Virology. 86: 8693-704. PMID 22674989 DOI: 10.1128/Jvi.00252-12  0.759
2012 Austgen K, Oakes SA, Ganem D. Multiple defects, including premature apoptosis, prevent Kaposi's sarcoma-associated herpesvirus replication in murine cells. Journal of Virology. 86: 1877-82. PMID 22130538 DOI: 10.1128/Jvi.06600-11  0.517
2011 Myoung J, Ganem D. Infection of lymphoblastoid cell lines by Kaposi's sarcoma-associated herpesvirus: critical role of cell-associated virus. Journal of Virology. 85: 9767-77. PMID 21795352 DOI: 10.1128/Jvi.05136-11  0.452
2011 Runckel C, Flenniken ML, Engel JC, Ruby JG, Ganem D, Andino R, DeRisi JL. Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia. Plos One. 6: e20656. PMID 21687739 DOI: 10.1371/Journal.Pone.0020656  0.408
2011 Myoung J, Ganem D. Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: maintenance of tight latency with efficient reactivation upon induction. Journal of Virological Methods. 174: 12-21. PMID 21419799 DOI: 10.1016/J.Jviromet.2011.03.012  0.391
2011 Myoung J, Ganem D. Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells. Virology. 413: 1-11. PMID 21353276 DOI: 10.1016/J.Virol.2010.12.036  0.407
2011 Myoung J, Ganem D. Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells. The Journal of Clinical Investigation. 121: 1130-40. PMID 21339648 DOI: 10.1172/Jci43755  0.388
2010 Greninger AL, Holtz L, Kang G, Ganem D, Wang D, DeRisi JL. Serological evidence of human klassevirus infection. Clinical and Vaccine Immunology : Cvi. 17: 1584-8. PMID 20739504 DOI: 10.1128/Cvi.00152-10  0.359
2010 Speck SH, Ganem D. Viral latency and its regulation: lessons from the gamma-herpesviruses. Cell Host & Microbe. 8: 100-15. PMID 20638646 DOI: 10.1016/J.Chom.2010.06.014  0.481
2010 Raghav R, Taylor M, Delay J, Ojkic D, Pearl DL, Kistler AL, Derisi JL, Ganem D, Smith DA. Avian bornavirus is present in many tissues of psittacine birds with histopathologic evidence of proventricular dilatation disease. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 22: 495-508. PMID 20622218 DOI: 10.1177/104063871002200402  0.353
2010 Yozwiak NL, Skewes-Cox P, Gordon A, Saborio S, Kuan G, Balmaseda A, Ganem D, Harris E, DeRisi JL. Human enterovirus 109: a novel interspecies recombinant enterovirus isolated from a case of acute pediatric respiratory illness in Nicaragua. Journal of Virology. 84: 9047-58. PMID 20592079 DOI: 10.1128/Jvi.00698-10  0.354
2010 Chandriani S, Xu Y, Ganem D. The lytic transcriptome of Kaposi's sarcoma-associated herpesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes. Journal of Virology. 84: 7934-42. PMID 20534856 DOI: 10.1128/Jvi.00645-10  0.413
2010 Ganem D, Kistler A, DeRisi J. Achalasia and viral infection: new insights from veterinary medicine. Science Translational Medicine. 2: 33ps24. PMID 20505212 DOI: 10.1126/Scitranslmed.3000986  0.351
2010 Ganem D. KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine. The Journal of Clinical Investigation. 120: 939-49. PMID 20364091 DOI: 10.1172/Jci40567  0.346
2010 Xu Y, Ganem D. Making sense of antisense: seemingly noncoding RNAs antisense to the master regulator of Kaposi's sarcoma-associated herpesvirus lytic replication do not regulate that transcript but serve as mRNAs encoding small peptides. Journal of Virology. 84: 5465-75. PMID 20357088 DOI: 10.1128/Jvi.02705-09  0.38
2010 Chandriani S, Ganem D. Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 84: 5565-73. PMID 20219929 DOI: 10.1128/Jvi.02723-09  0.441
2010 Chiu CY, Greninger AL, Chen EC, Haggerty TD, Parsonnet J, Delwart E, Derisi JL, Ganem D. Cultivation and serological characterization of a human Theiler's-like cardiovirus associated with diarrheal disease. Journal of Virology. 84: 4407-14. PMID 20164225 DOI: 10.1128/Jvi.02536-09  0.373
2010 Kistler AL, Smith JM, Greninger AL, Derisi JL, Ganem D. Analysis of naturally occurring avian bornavirus infection and transmission during an outbreak of proventricular dilatation disease among captive psittacine birds. Journal of Virology. 84: 2176-9. PMID 19955301 DOI: 10.1128/Jvi.02191-09  0.361
2009 Bellare P, Ganem D. Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host & Microbe. 6: 570-5. PMID 20006845 DOI: 10.1016/J.Chom.2009.11.008  0.382
2009 Gancz AY, Kistler AL, Greninger AL, Farnoushi Y, Mechani S, Perl S, Berkowitz A, Perez N, Clubb S, DeRisi JL, Ganem D, Lublin A. Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4. Virology Journal. 6: 100. PMID 19589169 DOI: 10.1186/1743-422X-6-100  0.399
2009 Greninger AL, Runckel C, Chiu CY, Haggerty T, Parsonnet J, Ganem D, DeRisi JL. The complete genome of klassevirus - a novel picornavirus in pediatric stool. Virology Journal. 6: 82. PMID 19538752 DOI: 10.1186/1743-422X-6-82  0.408
2009 Bisson SA, Page AL, Ganem D. A Kaposi's sarcoma-associated herpesvirus protein that forms inhibitory complexes with type I interferon receptor subunits, Jak and STAT proteins, and blocks interferon-mediated signal transduction. Journal of Virology. 83: 5056-66. PMID 19279093 DOI: 10.1128/Jvi.02516-08  0.398
2009 Sullivan CS, Sung CK, Pack CD, Grundhoff A, Lukacher AE, Benjamin TL, Ganem D. Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection. Virology. 387: 157-67. PMID 19272626 DOI: 10.1016/J.Virol.2009.02.017  0.441
2009 Ziegelbauer JM, Sullivan CS, Ganem D. Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nature Genetics. 41: 130-4. PMID 19098914 DOI: 10.1038/Ng.266  0.314
2009 Ganem D. 151 MicroRNAs and the biology of KSHV infection Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351107.16632.Dc  0.36
2008 Ganem D, Ziegelbauer J. MicroRNAs of Kaposi's sarcoma-associated herpes virus. Seminars in Cancer Biology. 18: 437-40. PMID 19013245 DOI: 10.1016/J.Semcancer.2008.10.006  0.393
2008 Chiu CY, Greninger AL, Kanada K, Kwok T, Fischer KF, Runckel C, Louie JK, Glaser CA, Yagi S, Schnurr DP, Haggerty TD, Parsonnet J, Ganem D, DeRisi JL. Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections. Proceedings of the National Academy of Sciences of the United States of America. 105: 14124-9. PMID 18768820 DOI: 10.1073/Pnas.0805968105  0.435
2008 Kistler AL, Gancz A, Clubb S, Skewes-Cox P, Fischer K, Sorber K, Chiu CY, Lublin A, Mechani S, Farnoushi Y, Greninger A, Wen CC, Karlene SB, Ganem D, DeRisi JL. Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent. Virology Journal. 5: 88. PMID 18671869 DOI: 10.1186/1743-422X-5-88  0.34
2008 Chiu CY, Urisman A, Greenhow TL, Rouskin S, Yagi S, Schnurr D, Wright C, Drew WL, Wang D, Weintrub PS, Derisi JL, Ganem D. Utility of DNA microarrays for detection of viruses in acute respiratory tract infections in children. The Journal of Pediatrics. 153: 76-83. PMID 18571541 DOI: 10.1016/J.Jpeds.2007.12.035  0.376
2008 Grossmann C, Ganem D. Effects of NFkappaB activation on KSHV latency and lytic reactivation are complex and context-dependent. Virology. 375: 94-102. PMID 18321555 DOI: 10.1016/J.Virol.2007.12.044  0.427
2007 Chandriani S, Ganem D. Host transcript accumulation during lytic KSHV infection reveals several classes of host responses. Plos One. 2: e811. PMID 17726541 DOI: 10.1371/Journal.Pone.0000811  0.461
2007 Kistler A, Avila PC, Rouskin S, Wang D, Ward T, Yagi S, Schnurr D, Ganem D, DeRisi JL, Boushey HA. Pan-viral screening of respiratory tract infections in adults with and without asthma reveals unexpected human coronavirus and human rhinovirus diversity. The Journal of Infectious Diseases. 196: 817-25. PMID 17703411 DOI: 10.1086/520816  0.367
2007 Chiu CY, Alizadeh AA, Rouskin S, Merker JD, Yeh E, Yagi S, Schnurr D, Patterson BK, Ganem D, DeRisi JL. Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray. Journal of Clinical Microbiology. 45: 2340-3. PMID 17494722 DOI: 10.1128/Jcm.00364-07  0.425
2007 Rowe M, Glaunsinger B, van Leeuwen D, Zuo J, Sweetman D, Ganem D, Middeldorp J, Wiertz EJ, Ressing ME. Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion. Proceedings of the National Academy of Sciences of the United States of America. 104: 3366-71. PMID 17360652 DOI: 10.1073/Pnas.0611128104  0.454
2007 Dong B, Kim S, Hong S, Das Gupta J, Malathi K, Klein EA, Ganem D, Derisi JL, Chow SA, Silverman RH. An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors. Proceedings of the National Academy of Sciences of the United States of America. 104: 1655-60. PMID 17234809 DOI: 10.1073/Pnas.0610291104  0.4
2007 Xu Y, Ganem D. Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. The Journal of General Virology. 88: 46-50. PMID 17170435 DOI: 10.1099/Vir.0.82375-0  0.37
2006 Ganem D. KSHV infection and the pathogenesis of Kaposi's sarcoma. Annual Review of Pathology. 1: 273-96. PMID 18039116 DOI: 10.1146/Annurev.Pathol.1.110304.100133  0.48
2006 Sullivan CS, Grundhoff A, Tevethia S, Treisman R, Pipas JM, Ganem D. Expression and function of microRNAs in viruses great and small. Cold Spring Harbor Symposia On Quantitative Biology. 71: 351-6. PMID 17381316 DOI: 10.1101/Sqb.2006.71.065  0.326
2006 Chiu CY, Rouskin S, Koshy A, Urisman A, Fischer K, Yagi S, Schnurr D, Eckburg PB, Tompkins LS, Blackburn BG, Merker JD, Patterson BK, Ganem D, DeRisi JL. Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 43: e71-6. PMID 16983602 DOI: 10.1086/507896  0.383
2006 Glaunsinger BA, Ganem DE. Messenger RNA turnover and its regulation in herpesviral infection. Advances in Virus Research. 66: 337-94. PMID 16877064 DOI: 10.1016/S0065-3527(06)66007-7  0.346
2006 Grossmann C, Podgrabinska S, Skobe M, Ganem D. Activation of NF-kappaB by the latent vFLIP gene of Kaposi's sarcoma-associated herpesvirus is required for the spindle shape of virus-infected endothelial cells and contributes to their proinflammatory phenotype. Journal of Virology. 80: 7179-85. PMID 16809323 DOI: 10.1128/Jvi.01603-05  0.414
2006 McCormick C, Ganem D. Phosphorylation and function of the kaposin B direct repeats of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 80: 6165-70. PMID 16731955 DOI: 10.1128/Jvi.02331-05  0.319
2006 Urisman A, Molinaro RJ, Fischer N, Plummer SJ, Casey G, Klein EA, Malathi K, Magi-Galluzzi C, Tubbs RR, Ganem D, Silverman RH, DeRisi JL. Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant. Plos Pathogens. 2: e25. PMID 16609730 DOI: 10.1371/Journal.Ppat.0020025  0.443
2006 Ziegelbauer J, Grundhoff A, Ganem D. Exploring the DNA binding interactions of the Kaposi's sarcoma-associated herpesvirus lytic switch protein by selective amplification of bound sequences in vitro. Journal of Virology. 80: 2958-67. PMID 16501105 DOI: 10.1128/Jvi.80.6.2958-2967.2006  0.398
2005 Sullivan CS, Ganem D. MicroRNAs and viral infection. Molecular Cell. 20: 3-7. PMID 16209940 DOI: 10.1016/J.Molcel.2005.09.012  0.333
2005 Bechtel J, Grundhoff A, Ganem D. RNAs in the virion of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 79: 10138-46. PMID 16051806 DOI: 10.1128/Jvi.79.16.10138-10146.2005  0.432
2005 Sullivan CS, Grundhoff AT, Tevethia S, Pipas JM, Ganem D. SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature. 435: 682-6. PMID 15931223 DOI: 10.1038/Nature03576  0.445
2005 Glaunsinger B, Chavez L, Ganem D. The exonuclease and host shutoff functions of the SOX protein of Kaposi's sarcoma-associated herpesvirus are genetically separable. Journal of Virology. 79: 7396-401. PMID 15919895 DOI: 10.1128/Jvi.79.12.7396-7401.2005  0.443
2005 Sullivan CS, Ganem D. A virus-encoded inhibitor that blocks RNA interference in mammalian cells. Journal of Virology. 79: 7371-9. PMID 15919892 DOI: 10.1128/Jvi.79.12.7371-7379.2005  0.36
2005 Sanchez DJ, Gumperz JE, Ganem D. Regulation of CD1d expression and function by a herpesvirus infection. The Journal of Clinical Investigation. 115: 1369-78. PMID 15864354 DOI: 10.1172/Jci24041  0.386
2005 Bechtel JT, Winant RC, Ganem D. Host and viral proteins in the virion of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 79: 4952-64. PMID 15795281 DOI: 10.1128/Jvi.79.8.4952-4964.2005  0.483
2005 McCormick C, Ganem D. The kaposin B protein of KSHV activates the p38/MK2 pathway and stabilizes cytokine mRNAs. Science (New York, N.Y.). 307: 739-41. PMID 15692053 DOI: 10.1126/Science.1105779  0.374
2004 Glaunsinger B, Ganem D. Highly selective escape from KSHV-mediated host mRNA shutoff and its implications for viral pathogenesis. The Journal of Experimental Medicine. 200: 391-8. PMID 15289507 DOI: 10.1084/Jem.20031881  0.451
2004 Liang Y, Ganem D. RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposi's sarcoma-associated herpesvirus by the lytic switch protein RTA. Journal of Virology. 78: 6818-26. PMID 15194757 DOI: 10.1128/Jvi.78.13.6818-6826.2004  0.413
2004 Renne R, Dittmer D, Kedes D, Schmidt K, Desrosiers RC, Luciw PA, Ganem D. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SIV-positive and SIV-negative rhesus macaques. Journal of Medical Primatology. 33: 1-9. PMID 15061726 DOI: 10.1046/J.1600-0684.2003.00043.X  0.398
2004 Glaunsinger B, Ganem D. Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnover. Molecular Cell. 13: 713-23. PMID 15023341 DOI: 10.1016/S1097-2765(04)00091-7  0.46
2004 Ganem D, Prince AM. Hepatitis B virus infection--natural history and clinical consequences. The New England Journal of Medicine. 350: 1118-29. PMID 15014185 DOI: 10.1056/Nejmra031087  0.43
2004 Grundhoff A, Ganem D. Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis. The Journal of Clinical Investigation. 113: 124-36. PMID 14702116 DOI: 10.1172/Jci17803  0.488
2003 Wang D, Urisman A, Liu YT, Springer M, Ksiazek TG, Erdman DD, Mardis ER, Hickenbotham M, Magrini V, Eldred J, Latreille JP, Wilson RK, Ganem D, DeRisi JL. Viral discovery and sequence recovery using DNA microarrays. Plos Biology. 1: E2. PMID 14624234 DOI: 10.1371/Journal.Pbio.0000002  0.448
2003 Liang Y, Ganem D. Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 100: 8490-5. PMID 12832621 DOI: 10.1073/Pnas.1432843100  0.531
2003 Bechtel JT, Liang Y, Hvidding J, Ganem D. Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells. Journal of Virology. 77: 6474-81. PMID 12743304 DOI: 10.1128/Jvi.77.11.6474-6481.2003  0.437
2003 Grundhoff A, Ganem D. The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids. Journal of Virology. 77: 2779-83. PMID 12552022 DOI: 10.1128/Jvi.77.4.2779-2783.2003  0.423
2003 Coscoy L, Ganem D. PHD domains and E3 ubiquitin ligases: viruses make the connection. Trends in Cell Biology. 13: 7-12. PMID 12480335 DOI: 10.1016/S0962-8924(02)00005-3  0.32
2003 Ganem D. Hepatitis B Virus Expert Review of Anti-Infective Therapy. 1: 357-358. DOI: 10.1586/14787210.1.3.357  0.356
2002 Wang D, Coscoy L, Zylberberg M, Avila PC, Boushey HA, Ganem D, DeRisi JL. Microarray-based detection and genotyping of viral pathogens. Proceedings of the National Academy of Sciences of the United States of America. 99: 15687-92. PMID 12429852 DOI: 10.1073/Pnas.242579699  0.439
2002 Liang Y, Chang J, Lynch SJ, Lukac DM, Ganem D. The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. Genes & Development. 16: 1977-89. PMID 12154127 DOI: 10.1101/Gad.996502  0.399
2002 Baron JL, Gardiner L, Nishimura S, Shinkai K, Locksley R, Ganem D. Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection. Immunity. 16: 583-94. PMID 11970881 DOI: 10.1016/S1074-7613(02)00305-9  0.405
2002 Lagunoff M, Bechtel J, Venetsanakos E, Roy AM, Abbey N, Herndier B, McMahon M, Ganem D. De novo infection and serial transmission of Kaposi's sarcoma-associated herpesvirus in cultured endothelial cells. Journal of Virology. 76: 2440-8. PMID 11836422 DOI: 10.1128/Jvi.76.5.2440-2448.2002  0.438
2001 Ganem D. Virology. The X files--one step closer to closure. Science (New York, N.Y.). 294: 2299-300. PMID 11743185 DOI: 10.1126/Science.1067850  0.339
2001 Liu YT, Brazas R, Ganem D. Efficient hepatitis delta virus RNA replication in avian cells requires a permissive factor(s) from mammalian cells. Journal of Virology. 75: 7489-93. PMID 11462021 DOI: 10.1128/Jvi.75.16.7489-7493.2001  0.459
2001 Lukac DM, Garibyan L, Kirshner JR, Palmeri D, Ganem D. DNA binding by Kaposi's sarcoma-associated herpesvirus lytic switch protein is necessary for transcriptional activation of two viral delayed early promoters. Journal of Virology. 75: 6786-99. PMID 11435557 DOI: 10.1128/Jvi.75.15.6786-6799.2001  0.43
2001 Brander C, O'Connor P, Suscovich T, Jones NG, Lee Y, Kedes D, Ganem D, Martin J, Osmond D, Southwood S, Sette A, Walker BD, Scadden DT. Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. The Journal of Infectious Diseases. 184: 119-26. PMID 11424007 DOI: 10.1086/322003  0.312
2001 Coscoy L, Ganem D. A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation. The Journal of Clinical Investigation. 107: 1599-606. PMID 11413168 DOI: 10.1172/Jci12432  0.384
2001 Lagunoff M, Lukac DM, Ganem D. Immunoreceptor tyrosine-based activation motif-dependent signaling by Kaposi's sarcoma-associated herpesvirus K1 protein: effects on lytic viral replication. Journal of Virology. 75: 5891-8. PMID 11390590 DOI: 10.1128/Jvi.75.13.5891-5898.2001  0.348
2001 Wang D, Pearlberg J, Liu YT, Ganem D. Deleterious effects of hepatitis delta virus replication on host cell proliferation. Journal of Virology. 75: 3600-4. PMID 11264349 DOI: 10.1128/Jvi.75.8.3600-3604.2001  0.469
2001 Polson AG, Huang L, Lukac DM, Blethrow JD, Morgan DO, Burlingame AL, Ganem D. Kaposi's sarcoma-associated herpesvirus K-bZIP protein is phosphorylated by cyclin-dependent kinases. Journal of Virology. 75: 3175-84. PMID 11238844 DOI: 10.1128/Jvi.75.7.3175-3184.2001  0.332
2001 Grundhoff A, Ganem D. Mechanisms governing expression of the v-FLIP gene of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 75: 1857-63. PMID 11160684 DOI: 10.1128/Jvi.75.4.1857-1863.2001  0.416
2001 Renne R, Barry C, Dittmer D, Compitello N, Brown PO, Ganem D. Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 75: 458-68. PMID 11119614 DOI: 10.1128/Jvi.75.1.458-468.2001  0.446
2000 Wu L, Renne R, Ganem D, Forghani B. Human herpesvirus 8 glycoprotein K8.1: expression, post-translational modification and localization analyzed by monoclonal antibody. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 17: 127-36. PMID 10942093 DOI: 10.1016/S1386-6532(00)00085-8  0.347
2000 Chang J, Ganem D. On the control of late gene expression in Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). The Journal of General Virology. 81: 2039-47. PMID 10900043 DOI: 10.1099/0022-1317-81-8-2039  0.467
2000 Coscoy L, Ganem D. Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 8051-6. PMID 10859362 DOI: 10.1073/Pnas.140129797  0.379
2000 Bell P, Brazas R, Ganem D, Maul GG. Hepatitis delta virus replication generates complexes of large hepatitis delta antigen and antigenomic RNA that affiliate with and alter nuclear domain 10. Journal of Virology. 74: 5329-36. PMID 10799610 DOI: 10.1128/Jvi.74.11.5329-5336.2000  0.454
2000 Kirshner JR, Lukac DM, Chang J, Ganem D. Kaposi's sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities. Journal of Virology. 74: 3586-97. PMID 10729134 DOI: 10.1128/Jvi.74.8.3586-3597.2000  0.464
2000 Chang J, Renne R, Dittmer D, Ganem D. Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication. Virology. 266: 17-25. PMID 10612656 DOI: 10.1006/Viro.1999.0077  0.348
1999 Dittmer D, Stoddart C, Renne R, Linquist-Stepps V, Moreno ME, Bare C, McCune JM, Ganem D. Experimental transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv mice. The Journal of Experimental Medicine. 190: 1857-68. PMID 10601360 DOI: 10.1084/Jem.190.12.1857  0.442
1999 Ganem D. An advance in liver-specific gene delivery Proceedings of the National Academy of Sciences of the United States of America. 96: 11696-11697. PMID 10518511 DOI: 10.1073/Pnas.96.21.11696  0.351
1999 Lukac DM, Kirshner JR, Ganem D. Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells Journal of Virology. 73: 9348-9361. PMID 10516043 DOI: 10.1128/Jvi.73.11.9348-9361.1999  0.507
1999 Kirshner JR, Staskus K, Haase A, Lagunoff M, Ganem D. Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: Implications for KS pathogenesis Journal of Virology. 73: 6006-6014. PMID 10364352 DOI: 10.1128/Jvi.73.7.6006-6014.1999  0.465
1999 Sadler R, Wu L, Forghani B, Renne R, Zhong W, Herndier B, Ganem D. A complex translational program generates multiple novel proteins from the latently expressed Kaposin (K12) locus of Kaposi's sarcoma-associated herpesvirus Journal of Virology. 73: 5722-5730. PMID 10364323 DOI: 10.1128/Jvi.73.7.5722-5730.1999  0.419
1999 Lagunoff M, Majeti R, Weiss A, Ganem D. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proceedings of the National Academy of Sciences of the United States of America. 96: 5704-9. PMID 10318948 DOI: 10.1073/Pnas.96.10.5704  0.332
1998 Lukac DM, Renne R, Kirshner JR, Ganem D. Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein Virology. 252: 304-312. PMID 9878608 DOI: 10.1006/Viro.1998.9486  0.505
1998 Blower S, Ganem D. Mathematicians turn their attention to hepatitis C. Nature Medicine. 4: 1233-4. PMID 9809538 DOI: 10.1038/3210  0.366
1998 Dittmer D, Lagunoff M, Renne R, Staskus K, Haase A, Ganem D. A cluster of latently expressed genes in Kaposi's sarcoma-associated herpesvirus Journal of Virology. 72: 8309-8315. PMID 9733875 DOI: 10.1128/Jvi.72.10.8309-8315.1998  0.438
1998 Wei YU, Tennant B, Ganem D. In vivo effects of mutations in woodchuck hepatitis virus enhancer II Journal of Virology. 72: 6608-6613. PMID 9658106 DOI: 10.1128/Jvi.72.8.6608-6613.1998  0.442
1998 Renne R, Blackbourn D, Whitby D, Levy J, Ganem D. Limited transmission of Kaposi's sarcoma-associated herpesvirus in cultured cells. Journal of Virology. 72: 5182-8. PMID 9573290 DOI: 10.1128/Jvi.72.6.5182-5188.1998  0.466
1998 Eng FJ, Novikova EG, Kuroki K, Ganem D, Fricker LD. gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity. The Journal of Biological Chemistry. 273: 8382-8. PMID 9525948 DOI: 10.1074/Jbc.273.14.8382  0.332
1998 Wei YU, Ganem D. Activation of heterologous gene expression by the large isoform of hepatitis delta antigen Journal of Virology. 72: 2089-2096. PMID 9499064 DOI: 10.1128/Jvi.72.3.2089-2096.1998  0.422
1998 Sadler R, Dittmer D, Lagunoff M, Ganem D. EXPRESSION OF LATENT HHV-8 GENES Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 17: A21. DOI: 10.1097/00042560-199804010-00054  0.302
1997 Kedes DH, Lagunoff M, Renne R, Ganem D. Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus Journal of Clinical Investigation. 100: 2606-2610. PMID 9366576 DOI: 10.1172/Jci119804  0.448
1997 Lagunoff M, Ganem D. The structure and coding organization of the genomic termini of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) Virology. 236: 147-154. PMID 9299627 DOI: 10.1006/Viro.1997.8713  0.438
1997 Diamond C, Huang ML, Kedes DH, Speck C, Rankin GW, Ganem D, Coombs RW, Rose TM, Krieger JN, Corey L. Absence of detectable human herpesvirus 8 in the semen of human immunodeficiency virus-infected men without Kaposi's sarcoma. The Journal of Infectious Diseases. 176: 775-7. PMID 9291331 DOI: 10.1086/517299  0.386
1997 Ünal A, Pray TR, Lagunoff M, Pennington MW, Ganem D, Craik CS. The protease and the assembly protein of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) Journal of Virology. 71: 7030-7038. PMID 9261433 DOI: 10.1128/Jvi.71.9.7030-7038.1997  0.428
1997 Orenstein JM, Alkan S, Blauvelt A, Jeang KT, Weinstein MD, Ganem D, Herndier B. Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy Aids. 11: F35-F45. PMID 9108935 DOI: 10.1097/00002030-199705000-00001  0.38
1997 Staskus KA, Zhong W, Gebhard K, Herndier B, Wang H, Renne R, Beneke J, Pudney J, Anderson DJ, Ganem D, Haase AT. Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells Journal of Virology. 71: 715-719. PMID 8985403 DOI: 10.1128/Jvi.71.1.715-719.1997  0.415
1997 Herndier B, Shiramizu B, Weinstein M, Ganem D, Orenstein JM. KSHV LATENT AND LYTIC INFECTION IN KAPOSI'S SARCOMA LESIONS AND LYMPHOID TISSUE Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 14: A25. DOI: 10.1097/00042560-199704010-00079  0.315
1997 Ganem D. LATENT AND LYTIC REPLICATION OF HHV8/KSHV Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 14: A14. DOI: 10.1097/00042560-199704010-00035  0.398
1996 Renne R, Lagunoff M, Zhong W, Ganem D. The size and conformation of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in infected cells and virions Journal of Virology. 70: 8151-8154. PMID 8892944 DOI: 10.1128/Jvi.70.11.8151-8154.1996  0.482
1996 Brazas R, Ganem D. A cellular homolog of hepatitis delta antigen: Implications for viral replication and evolution Science. 274: 90-94. PMID 8810253 DOI: 10.1126/Science.274.5284.90  0.502
1996 Wei Y, Tavis JE, Ganem D. Relationship between viral DNA synthesis and virion envelopment in hepatitis B viruses Journal of Virology. 70: 6455-6458. PMID 8709281 DOI: 10.1128/Jvi.70.9.6455-6458.1996  0.415
1996 Tavis JE, Ganem D. Evidence for activation of the hepatitis B virus polymerase by binding of its RNA template Journal of Virology. 70: 5741-5750. PMID 8709189 DOI: 10.1128/Jvi.70.9.5741-5750.1996  0.404
1996 Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D. The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission Nature Medicine. 2: 918-924. PMID 8705863 DOI: 10.1038/Nm0896-918  0.338
1996 Zhong W, Wang H, Herndier B, Ganem D. Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma Proceedings of the National Academy of Sciences of the United States of America. 93: 6641-6646. PMID 8692871 DOI: 10.1073/Pnas.93.13.6641  0.488
1996 Ueda K, Wei YU, Ganem D. Cellular factors controlling the activity of woodchuck hepatitis virus enhancer II Journal of Virology. 70: 4714-4723. PMID 8676498 DOI: 10.1128/Jvi.70.7.4714-4723.1996  0.41
1996 Ziermann R, Ganem D. Homologous and heterologous complementation of HBV and WHV capsid and polymerase functions in RNA encapsidation Virology. 219: 350-356. PMID 8638400 DOI: 10.1006/Viro.1996.0260  0.413
1996 Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture Nature Medicine. 2: 342-346. PMID 8612236 DOI: 10.1038/Nm0396-342  0.432
1996 Ueda K, Wei Y, Ganem D. Activation of N-myc2 gene expression by cis-acting elements of oncogenic hepadnaviral genomes: Key role of enhancer II Virology. 217: 413-417. PMID 8599232 DOI: 10.1006/Viro.1996.0133  0.425
1996 Chuck S, Grant RM, Katongole-Mbidde E, Conant M, Ganem D. Frequent presence of a novel herpesvirus genome in lesions of human immunodeficiency virus-negative Kaposi's sarcoma Journal of Infectious Diseases. 173: 248-251. PMID 8537669 DOI: 10.1093/Infdis/173.1.248  0.364
1996 Ganem D. Human herpesvirus 8 and the biology of Kaposi's sarcoma Seminars in Virology. 7: 325-332. DOI: 10.1006/Smvy.1996.0040  0.374
1995 Chang C, Hirsch RC, Ganem D. Sequences in the PreC region of duck hepatitis B virus affect pregenomic RNA accumulation Virology. 207: 549-554. PMID 7886958 DOI: 10.1006/Viro.1995.1115  0.384
1995 Kuroki K, Eng F, Ishikawa T, Turck C, Harada F, Ganem D. gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family. The Journal of Biological Chemistry. 270: 15022-8. PMID 7797483 DOI: 10.1074/Jbc.270.25.15022  0.413
1995 Tavis JE, Ganem D. RNA sequences controlling the initiation and transfer of duck hepatitis B virus minus-strand DNA Journal of Virology. 69: 4283-4291. PMID 7769689 DOI: 10.1128/Jvi.69.7.4283-4291.1995  0.379
1995 Ishikawa T, Ganem D. The pre-S domain of the large viral envelope protein determines host range in avian hepatitis B viruses Proceedings of the National Academy of Sciences of the United States of America. 92: 6259-6263. PMID 7603980 DOI: 10.1073/Pnas.92.14.6259  0.464
1995 Ganem D. AIDS: Viruses, cytokines and Kaposi's sarcoma Current Biology. 5: 469-471. PMID 7583090 DOI: 10.1016/S0960-9822(95)00093-5  0.378
1994 Tavis JE, Perri S, Ganem D. Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer Journal of Virology. 68: 3536-3543. PMID 8189492 DOI: 10.1128/Jvi.68.6.3536-3543.1994  0.424
1994 Ishikawa T, Kuroki K, Lenhoff R, Summers J, Ganem D. Analysis of the binding of a host cell surface glycoprotein to the preS protein of duck hepatitis B virus Virology. 202: 1061-1064. PMID 8030212 DOI: 10.1006/Viro.1994.1440  0.4
1994 Lingappa JR, Martin RL, Wong ML, Ganem D, Welch WJ, Lingappa VR. A eukaryotic cytosolic chaperonin is associated with a high molecular weight intermediate in the assembly of hepatitis B virus capsid, a multimeric particle. The Journal of Cell Biology. 125: 99-111. PMID 7908022 DOI: 10.1083/Jcb.125.1.99  0.381
1994 Ganem D. Emerging viruses Cell. 76: 599-600. DOI: 10.1016/0092-8674(94)90499-5  0.316
1993 Hansen LJ, Tennant BC, Seeger C, Ganem D. Differential activation of myc gene family members in hepatic carcinogenesis by closely related hepatitis B viruses. Molecular and Cellular Biology. 13: 659-67. PMID 8380230 DOI: 10.1128/Mcb.13.1.659  0.39
1993 Tan M, Klein R, Grant R, Ganem D, Engel J. Cloning and characterization of the RNA polymerase α-subunit operon of Chlamydia trachomatis Journal of Bacteriology. 175: 7150-7159. PMID 8226662 DOI: 10.1128/Jb.175.22.7150-7159.1993  0.349
1993 Lavine JE, Ganem D. Inhibition of duck hepatitis B virus replication by interferon-γ Journal of Medical Virology. 40: 59-64. PMID 7685809 DOI: 10.1002/Jmv.1890400112  0.456
1993 Tavis JE, Ganem D. Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription Proceedings of the National Academy of Sciences of the United States of America. 90: 4107-4111. PMID 7683422 DOI: 10.1073/Pnas.90.9.4107  0.482
1992 Perara E, Ganem D, Engel JN. A developmentally regulated chlamydial gene with apparent homology to eukaryotic histone H1 Proceedings of the National Academy of Sciences of the United States of America. 89: 2125-2129. PMID 1549572 DOI: 10.1073/Pnas.89.6.2125  0.359
1991 Hirsch RC, Loeb DD, Pollack JR, Ganem D. cis-Acting sequences required for encapsidation of duck hepatitis B virus pregenomic RNA Journal of Virology. 65: 3309-3316. PMID 2033673 DOI: 10.1128/Jvi.65.6.3309-3316.1991  0.415
1991 Seeger C, Baldwin B, Hornbuckle WE, Yeager AE, Tennant BC, Cote P, Ferrell L, Ganem D, Varmus HE. Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host. Journal of Virology. 65: 1673-9. PMID 2002538 DOI: 10.1128/Jvi.65.4.1673-1679.1991  0.398
1991 Macrae DR, Bruss V, Ganem D. Myristylation of a duck hepatitis B virus envelope protein is essential for infectivity but not for virus assembly Virology. 181: 359-363. PMID 1994583 DOI: 10.1016/0042-6822(91)90503-4  0.481
1991 Bruss V, Ganem D. The role of envelope proteins in hepatitis B virus assembly Proceedings of the National Academy of Sciences of the United States of America. 88: 1059-1063. PMID 1992457 DOI: 10.1073/Pnas.88.3.1059  0.393
1990 Eble BE, Lingappa VR, Ganem D. The N-terminal (pre-S2) domain of a hepatitis B virus surface glycoprotein is translocated across membranes by downstream signal sequences. Journal of Virology. 64: 1414-9. PMID 2304150 DOI: 10.1128/Jvi.64.3.1414-1419.1990  0.371
1990 Engel JN, Pollack J, Perara E, Ganem D. Heat shock response of murine Chlamydia trachomatis Journal of Bacteriology. 172: 6959-6972. PMID 2254267 DOI: 10.1128/Jb.172.12.6959-6972.1990  0.331
1990 Engel JN, Pollack J, Malik F, Ganem D. Cloning and characterization of RNA polymerase core subunits of Chlamydia trachomatis by using the polymerae chain reaction Journal of Bacteriology. 172: 5732-5741. PMID 2211507 DOI: 10.1128/Jb.172.10.5732-5741.1990  0.316
1990 Engel JN, Ganem D. A polymerase chain reaction-based approach to cloning sigma factors from eubacteria and its application to the isolation of a sigma-70 homolog from Chlamydia trachomatis Journal of Bacteriology. 172: 2447-2455. PMID 2110143 DOI: 10.1128/Jb.172.5.2447-2455.1990  0.353
1990 Chang LJ, Hirsch RC, Ganem D, Varmus HE. Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymerase. Journal of Virology. 64: 5553-8. PMID 1698997 DOI: 10.1128/Jvi.64.11.5553-5558.1990  0.42
1990 Chang LJ, Ganem D, Varmus HE. Mechanism of translation of the hepadnaviral polymerase (P) gene. Proceedings of the National Academy of Sciences of the United States of America. 87: 5158-62. PMID 1695011 DOI: 10.1073/Pnas.87.13.5158  0.348
1990 Kuroki K, Floreani M, Mimms LT, Ganem D. Epitope mapping of the PreS1 domain of the hepatitis B virus large surface protein Virology. 176: 620-624. PMID 1693249 DOI: 10.1016/0042-6822(90)90032-M  0.377
1990 Hirsch RC, Lavine JE, Chang LJ, Varmus HE, Ganem D. Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as wel as for reverse transcription. Nature. 344: 552-5. PMID 1690862 DOI: 10.1038/344552A0  0.412
1989 Colgrove R, Simon G, Ganem D. Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication Journal of Virology. 63: 4019-4026. PMID 2788226 DOI: 10.1128/Jvi.63.9.4019-4026.1989  0.455
1989 Lavine J, Hirsch R, Ganem D. A system for studying the selective encapsidation of hepadnavirus RNA Journal of Virology. 63: 4257-4263. PMID 2778874 DOI: 10.1128/Jvi.63.10.4257-4263.1989  0.446
1989 Sardinia LM, Engel JN, Ganem D. Chlamydial gene encoding a 70-kilodalton antigen in Escherichia coli: Analysis of expression signals and identification of the gene product Journal of Bacteriology. 171: 335-341. PMID 2644193 DOI: 10.1128/Jb.171.1.335-341.1989  0.371
1989 Kuroki K, Russnak R, Ganem D. Novel N-terminal amino acid sequence required for retention of a hepatitis B virus glycoprotein in the endoplasmic reticulum Molecular and Cellular Biology. 9: 4459-4466. PMID 2586518 DOI: 10.1128/Mcb.9.10.4459  0.377
1989 Chang LJ, Pryciak P, Ganem D, Varmus HE. Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting. Nature. 337: 364-8. PMID 2463489 DOI: 10.1038/337364A0  0.44
1988 Simon K, Lingappa VR, Ganem D. A block to the intracellular transport and assembly of hepatitis B surface antigen polypeptides in Xenopus oocytes. Virology. 166: 76-81. PMID 3413987 DOI: 10.1016/0042-6822(88)90148-1  0.355
1988 Simon K, Lingappa VR, Ganem D. Secreted hepatitis B surface antigen polypeptides are derived from a transmembrane precursor. The Journal of Cell Biology. 107: 2163-8. PMID 3198683 DOI: 10.1083/Jcb.107.6.2163  0.414
1988 Hirsch R, Colgrove R, Ganem D. Replication of duck hepatitis B virus in two differentiated human hepatoma cell lines after transfection with cloned viral DNA. Virology. 167: 136-42. PMID 2847409 DOI: 10.1016/0042-6822(88)90062-1  0.476
1987 Eble BE, MacRae DR, Lingappa VR, Ganem D. Multiple topogenic sequences determine the transmembrane orientation of the hepatitis B surface antigen. Molecular and Cellular Biology. 7: 3591-601. PMID 3683395 DOI: 10.1128/Mcb.7.10.3591  0.301
1987 Sprengel R, Varmus HE, Ganem D. Homologous recombination between hepadnaviral genomes following in vivo DNA transfection: implications for studies of viral infectivity. Virology. 159: 454-6. PMID 3617505 DOI: 10.1016/0042-6822(87)90486-7  0.468
1987 Persing DH, Varmus HE, Ganem D. The preS1 protein of hepatitis B virus is acylated at its amino terminus with myristic acid Journal of Virology. 61: 1672-1677. PMID 3573147 DOI: 10.1128/Jvi.61.5.1672-1677.1987  0.382
1987 Chang C, Enders G, Sprengel R, Peters N, Varmus HE, Ganem D. Expression of the precore region of an avian hepatitis B virus is not required for viral replication. Journal of Virology. 61: 3322-5. PMID 3041052 DOI: 10.1128/Jvi.61.10.3322-3325.1987  0.493
1987 Seeger C, Marion PL, Ganem D, Varmus HE. In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels. Journal of Virology. 61: 3241-7. PMID 3041044 DOI: 10.1128/Jvi.61.10.3241-3247.1987  0.487
1987 Ganem D, Varmus HE. The molecular biology of the hepatitis B viruses Annual Review of Biochemistry. 56: 651-693. PMID 3039907 DOI: 10.1146/Annurev.Bi.56.070187.003251  0.315
1987 Engel JN, Ganem D. Chlamydial rRNA operons: Gene organization and identification of putative tandem promoters Journal of Bacteriology. 169: 5678-5685. PMID 2445732 DOI: 10.1128/Jb.169.12.5678-5685.1987  0.39
1987 Enders GH, Ganem D, Varmus HE. 5'-Terminal sequences influence the segregation of ground squirrel hepatitis virus RNAs into polyribosomes and viral core particles Journal of Virology. 61: 35-41. PMID 2431165 DOI: 10.1128/Jvi.61.1.35-41.1987  0.431
1987 Seeger C, Marion PL, Ganem D, Varmus HE. In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels. Journal of Virology. 61: 3241-3247. DOI: 10.1128/jvi.61.10.3241-3247.1987  0.308
1986 Seeger C, Ganem D, Varmus HE. Biochemical and genetic evidence for the hepatitis B virus replication strategy. Science (New York, N.Y.). 232: 477-84. PMID 3961490 DOI: 10.1126/Science.3961490  0.436
1986 Persing DH, Varmus HE, Ganem D. Inhibition of secretion of hepatitis B surface antigen by a related presurface polypeptide Science. 234: 1388-1391. PMID 3787251 DOI: 10.1126/Science.3787251  0.422
1986 Eble BE, Lingappa VR, Ganem D. Hepatitis B surface antigen: an unusual secreted protein initially synthesized as a transmembrane polypeptide. Molecular and Cellular Biology. 6: 1454-63. PMID 3023891 DOI: 10.1128/Mcb.6.5.1454  0.35
1986 Persing DH, Varmus HE, Ganem D. Antibodies to pre-S and X determinants arise during natural infection with ground squirrel hepatitis virus Journal of Virology. 60: 177-184. PMID 2427746 DOI: 10.1128/Jvi.60.1.177-184.1986  0.433
1985 Trueba D, Phelan M, Nelson J, Beck F, Pecha BS, Brown RJ, Varmus HE, Ganem D. Transmission of ground squirrel hepatitis virus to homologous and heterologous hosts Hepatology. 5: 435-439. PMID 3997073 DOI: 10.1002/Hep.1840050316  0.31
1985 Persing DH, Varmus HE, Ganem D. A frameshift mutation in the pre-S region of the human hepatitis B virus genome allows production of surface antigen particles but eliminates binding to polymerized albumin Proceedings of the National Academy of Sciences of the United States of America. 82: 3440-3444. PMID 3858831 DOI: 10.1073/Pnas.82.10.3440  0.379
1985 Enders GH, Ganem D, Varmus H. Mapping the major transcripts of ground squirrel hepatitis virus: the presumptive template for reverse transcriptase is terminally redundant. Cell. 42: 297-308. PMID 2410139 DOI: 10.1016/S0092-8674(85)80125-2  0.493
1984 Standring DN, Rutter WJ, Varmus HE, Ganem D. Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region Journal of Virology. 50: 563-571. PMID 6200609 DOI: 10.1128/Jvi.50.2.563-571.1984  0.473
1984 Seeger C, Ganem D, Varmus HE. The cloned genome of ground squirrel hepatitis virus is infectious in the animal. Proceedings of the National Academy of Sciences of the United States of America. 81: 5849-52. PMID 6091114 DOI: 10.1073/Pnas.81.18.5849  0.483
1984 Seeger C, Ganem D, Varmus HE. Nucleotide sequence of an infectious molecularly cloned genome of ground squirrel hepatitis virus. Journal of Virology. 51: 367-75. PMID 6086950 DOI: 10.1128/Jvi.51.2.367-375.1984  0.468
1983 Weiser B, Ganem D, Seeger C, Varmus HE. Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus. Journal of Virology. 48: 1-9. PMID 6887347 DOI: 10.1128/Jvi.48.1.1-9.1983  0.404
1983 Ganem D. Persistent infection of humans with hepatitis B virus: mechanisms and consequences. Reviews of Infectious Diseases. 4: 1026-47. PMID 6293033 DOI: 10.1093/Clinids/4.5.1026  0.428
1982 Ganem D, Weiser B, Barchuk A, Brown RJ, Varmus HE. Biological characterization of acute infection with ground squirrel hepatitis virus Journal of Virology. 44: 366-373. PMID 7143570 DOI: 10.1128/Jvi.44.1.366-373.1982  0.45
1982 Ganem D, Greenbaum L, Varmus HE. Virion DNA of ground squirrel hepatitis virus: Structural analysis and molecular cloning Journal of Virology. 44: 374-383. PMID 6292498 DOI: 10.1128/Jvi.44.1.374-383.1982  0.44
1973 Ganem D, Miller JH, Files JG, Platt T, Weber K. Reinitiation of a lac repressor fragment at a codon other than AUG Proceedings of the National Academy of Sciences of the United States of America. 70: 3165-3169. PMID 4594037 DOI: 10.1073/Pnas.70.11.3165  0.323
1972 Platt T, Weber K, Ganem D, Miller JH. Translational restarts: AUG reinitiation of a lac repressor fragment Proceedings of the National Academy of Sciences of the United States of America. 69: 897-901. PMID 4554534 DOI: 10.1073/Pnas.69.4.897  0.315
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