David T. Rutkowski, Ph.D. - Publications

University of California, San Francisco, San Francisco, CA 
secretory pathway, cell biology, prions, cell-free systems

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Jo F, Jo H, Hilzendeger AM, Thompson AP, Cassell MD, Rutkowski DT, Davisson RL, Grobe JL, Sigmund CD. Brain endoplasmic reticulum stress mechanistically distinguishes the saline-intake and hypertensive response to deoxycorticosterone acetate-salt. Hypertension. 65: 1341-8. PMID 25895586 DOI: 10.1161/HYPERTENSIONAHA.115.05377  0.64
2014 Mao HZ, Ehrhardt N, Bedoya C, Gomez JA, DeZwaan-McCabe D, Mungrue IN, Kaufman RJ, Rutkowski DT, Péterfy M. Lipase maturation factor 1 (lmf1) is induced by endoplasmic reticulum stress through activating transcription factor 6α (Atf6α) signaling. The Journal of Biological Chemistry. 289: 24417-27. PMID 25035425 DOI: 10.1074/jbc.M114.588764  0.64
2014 Hassan I, Gaines KS, Hottel WJ, Wishy RM, Miller SE, Powers LS, Rutkowski DT, Monick MM. Inositol-requiring enzyme 1 inhibits respiratory syncytial virus replication. The Journal of Biological Chemistry. 289: 7537-46. PMID 24497642 DOI: 10.1074/jbc.M113.510594  0.64
2014 Gomez JA, Tyra HM, DeZwaan-McCabe D, Olivier AK, Rutkowski DT. Synthetic embryonic lethality upon deletion of the ER cochaperone p58(IPK) and the ER stress sensor ATF6α. Biochemical and Biophysical Research Communications. 443: 115-9. PMID 24275136 DOI: 10.1016/j.bbrc.2013.11.060  0.64
2013 DeZwaan-McCabe D, Riordan JD, Arensdorf AM, Icardi MS, Dupuy AJ, Rutkowski DT. The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis. Plos Genetics. 9: e1003937. PMID 24367269 DOI: 10.1371/journal.pgen.1003937  0.64
2013 Arensdorf AM, Diedrichs D, Rutkowski DT. Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences. Frontiers in Genetics. 4: 256. PMID 24348511 DOI: 10.3389/fgene.2013.00256  0.64
2013 Arensdorf AM, Rutkowski DT. Endoplasmic reticulum stress impairs IL-4/IL-13 signaling through C/EBPβ-mediated transcriptional suppression. Journal of Cell Science. 126: 4026-36. PMID 23813955 DOI: 10.1242/jcs.130757  0.64
2013 Sadighi Akha AA, Theriot CM, Erb-Downward JR, McDermott AJ, Falkowski NR, Tyra HM, Rutkowski DT, Young VB, Huffnagle GB. Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology. 140: 111-22. PMID 23668260 DOI: 10.1111/imm.12122  0.64
2013 Chikka MR, McCabe DD, Tyra HM, Rutkowski DT. C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver. The Journal of Biological Chemistry. 288: 4405-15. PMID 23281479 DOI: 10.1074/jbc.M112.432344  0.64
2012 Hassan IH, Zhang MS, Powers LS, Shao JQ, Baltrusaitis J, Rutkowski DT, Legge K, Monick MM. Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. The Journal of Biological Chemistry. 287: 4679-89. PMID 22194594 DOI: 10.1074/jbc.M111.284695  0.64
2012 Zagorodna O, Martin SM, Rutkowski DT, Kuwana T, Spitz DR, Knudson CM. 2-deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines. Oncogene. 31: 2738-49. PMID 21986940 DOI: 10.1038/onc.2011.454  0.64
2011 Sadighi Akha AA, Harper JM, Salmon AB, Schroeder BA, Tyra HM, Rutkowski DT, Miller RA. Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevity. The Journal of Biological Chemistry. 286: 30344-51. PMID 21757703 DOI: 10.1074/jbc.M111.220541  0.64
2011 Wu J, Ruas JL, Estall JL, Rasbach KA, Choi JH, Ye L, Boström P, Tyra HM, Crawford RW, Campbell KP, Rutkowski DT, Kaufman RJ, Spiegelman BM. The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex. Cell Metabolism. 13: 160-9. PMID 21284983 DOI: 10.1016/j.cmet.2011.01.003  0.64
2010 Rutkowski DT, Hegde RS. Regulation of basal cellular physiology by the homeostatic unfolded protein response. The Journal of Cell Biology. 189: 783-94. PMID 20513765 DOI: 10.1083/jcb.201003138  0.64
2009 Rutkowski DT. A gluconeogenic tryst in the nucleus, with ER stress as the third wheel. Science Signaling. 2: pe72. PMID 19903938 DOI: 10.1126/scisignal.296pe72  0.64
2009 Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT, Kaufman RJ, Ruse CI, Yates JR, Perrin S, Feany MB, Horwich AL. Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Proceedings of the National Academy of Sciences of the United States of America. 106: 1392-7. PMID 19171884 DOI: 10.1073/pnas.0813045106  0.64
2008 Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, Clark R, Miao H, Hassler JR, Fornek J, Katze MG, Hussain MM, Song B, Swathirajan J, Wang J, et al. UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Developmental Cell. 15: 829-40. PMID 19081072 DOI: 10.1016/j.devcel.2008.10.015  0.64
2007 Rutkowski DT, Kaufman RJ. That which does not kill me makes me stronger: adapting to chronic ER stress. Trends in Biochemical Sciences. 32: 469-76. PMID 17920280 DOI: 10.1016/j.tibs.2007.09.003  0.64
2007 Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, Wang J, Song B, Yau GD, Kaufman RJ. ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. Developmental Cell. 13: 351-64. PMID 17765679 DOI: 10.1016/j.devcel.2007.07.005  0.64
2007 Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hegde RS. The role of p58IPK in protecting the stressed endoplasmic reticulum. Molecular Biology of the Cell. 18: 3681-91. PMID 17567950 DOI: 10.1091/mbc.E07-03-0272  0.64
2006 Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, Kaufman RJ. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. Plos Biology. 4: e374. PMID 17090218 DOI: 10.1371/journal.pbio.0040374  0.64
2006 Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell. 124: 587-99. PMID 16469704 DOI: 10.1016/j.cell.2005.11.040  0.64
2004 Rutkowski DT, Kaufman RJ. A trip to the ER: coping with stress. Trends in Cell Biology. 14: 20-8. PMID 14729177 DOI: 10.1016/j.tcb.2003.11.001  0.64
2003 Rutkowski DT, Ott CM, Polansky JR, Lingappa VR. Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen. The Journal of Biological Chemistry. 278: 30365-72. PMID 12771148 DOI: 10.1074/jbc.M302117200  0.64
2003 Rutkowski DT, Kaufman RJ. All roads lead to ATF4. Developmental Cell. 4: 442-4. PMID 12689582 DOI: 10.1016/S1534-5807(03)00100-X  0.64
2002 Lingappa VR, Rutkowski DT, Hegde RS, Andersen OS. Conformational control through translocational regulation: a new view of secretory and membrane protein folding. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 741-8. PMID 12210535 DOI: 10.1002/bies.10130  0.64
2001 Rutkowski DT, Lingappa VR, Hegde RS. Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences. Proceedings of the National Academy of Sciences of the United States of America. 98: 7823-8. PMID 11416167 DOI: 10.1073/pnas.141125098  0.64
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