Kenneth E. Huffman, Ph.D. - Publications

Affiliations: 
University of Texas at Dallas, Richardson, TX, United States 
Area:
Biophysical Chemistry of protein-DNA interactions

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang XD, Hu R, Ding Q, Savage TK, Huffman KE, Williams N, Cobb MH, Minna JD, Johnson JE, Yu Y. Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells. Nature Communications. 10: 3201. PMID 31324758 DOI: 10.1038/s41467-019-11153-5  0.6
2019 Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, et al. Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. PMID 31043737 DOI: 10.1038/s41586-019-1133-3  0.6
2018 Huang F, Ni M, Chalishazar MD, Huffman KE, Kim J, Cai L, Shi X, Cai F, Zacharias LG, Ireland AS, Li K, Gu W, Kaushik AK, Liu X, Gazdar AF, et al. Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers. Cell Metabolism. PMID 30043754 DOI: 10.1016/j.cmet.2018.06.005  0.6
2017 Zhao X, Huffman KE, Fujimoto J, Canales JR, Girard L, Nie G, Heymach JV, Wistuba II, Minna JD, Yu Y. Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer. Journal of the American Society For Mass Spectrometry. PMID 28752479 DOI: 10.1007/s13361-017-1706-z  0.6
2017 Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, et al. CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells. Nature. PMID 28538732 DOI: 10.1038/nature22359  0.6
2016 Yan Y, Liu L, Xiong H, Miller JB, Zhou K, Kos P, Huffman KE, Elkassih S, Norman JW, Carstens R, Kim J, Minna JD, Siegwart DJ. Functional polyesters enable selective siRNA delivery to lung cancer over matched normal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621434 DOI: 10.1073/pnas.1606886113  0.32
2016 Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, et al. Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. Cell Reports. PMID 27477280 DOI: 10.1016/j.celrep.2016.07.009  0.32
2016 DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nature Genetics. 48: 473. PMID 27023779 DOI: 10.1038/ng0329-473a  0.6
2016 Hu R, Huffman KE, Chu M, Zhang Y, Minna JD, Yu Y. Quantitative Secretomic Analysis Identifies Extracellular Protein Factors that Modulate the Metastatic Phenotype of Non-Small Cell Lung Cancer. Journal of Proteome Research. PMID 26736068 DOI: 10.1021/acs.jproteome.5b00819  0.32
2015 Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis CM, Um SW, Kim DH, Ahn JM, et al. Cancer-specific production of N-acetylaspartate via NAT8L overexpression in non-small cell lung cancer and its potential as a circulating biomarker. Cancer Prevention Research (Philadelphia, Pa.). PMID 26511490 DOI: 10.1158/1940-6207.CAPR-14-0287  0.32
2015 DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. NRF2 regulates serine biosynthesis in non-small cell lung cancer. Nature Genetics. PMID 26482881 DOI: 10.1038/ng.3421  0.32
2015 Elkin SR, Bendris N, Reis C, Zhou Y, Xie Y, Huffman KE, Minna JD, Schmid SL. A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells. Cancer Research. PMID 26359453 DOI: 10.1158/0008-5472.CAN-15-0939  0.32
2015 Huffman KE, Carstens R, Martinez ED. A Subset of Nuclear Receptors are Uniquely Expressed in Uveal Melanoma Cells. Frontiers in Endocrinology. 6: 93. PMID 26217306 DOI: 10.3389/fendo.2015.00093  0.32
2015 Gu G, Gelsomino L, Covington KR, Beyer AR, Wang J, Rechoum Y, Huffman K, Carstens R, Andò S, Fuqua SA. Targeting thyroid hormone receptor beta in triple-negative breast cancer. Breast Cancer Research and Treatment. 150: 535-45. PMID 25820519 DOI: 10.1007/s10549-015-3354-y  1
2015 Tian H, Lu JY, Shao C, Huffman KE, Carstens RM, Larsen JE, Girard L, Liu H, Rodriguez-Canales J, Frenkel EP, Wistuba II, Minna JD, Hofmann SL. Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5. Molecular Cancer Research : McR. 13: 784-94. PMID 25573953 DOI: 10.1158/1541-7786.MCR-14-0608  0.32
2014 Srivastava N, Kollipara RK, Singh DK, Sudderth J, Hu Z, Nguyen H, Wang S, Humphries CG, Carstens R, Huffman KE, DeBerardinis RJ, Kittler R. Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels. Cell Metabolism. 20: 650-61. PMID 25264247 DOI: 10.1016/j.cmet.2014.08.003  0.32
2013 Huffman K, Martinez ED. Pre-clinical studies of epigenetic therapies targeting histone modifiers in lung cancer Frontiers in Oncology. 3. DOI: 10.3389/fonc.2013.00235  1
2012 Rudin CM, Durinck S, Stawiski EW, Poirier JT, Modrusan Z, Shames DS, Bergbower EA, Guan Y, Shin J, Guillory J, Rivers CS, Foo CK, Bhatt D, Stinson J, Gnad F, ... ... Huffman KE, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nature Genetics. 44: 1111-6. PMID 22941189 DOI: 10.1038/ng.2405  1
2007 Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR. Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nature Chemical Biology. 3: 166-73. PMID 17259978 DOI: 10.1038/nchembio860  1
2006 Janowski BA, Huffman KE, Schwartz JC, Ram R, Nordsell R, Shames DS, Minna JD, Corey DR. Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nature Structural & Molecular Biology. 13: 787-92. PMID 16936728 DOI: 10.1038/nsmb1140  1
2005 Janowski BA, Huffman KE, Schwartz JC, Ram R, Hardy D, Shames DS, Minna JD, Corey DR. Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs. Nature Chemical Biology. 1: 216-22. PMID 16408038 DOI: 10.1038/nchembio725  1
2005 Janowski BA, Kaihatsu K, Huffman KE, Schwartz JC, Ram R, Hardy D, Mendelson CR, Corey DR. Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids. Nature Chemical Biology. 1: 210-5. PMID 16408037 DOI: 10.1038/nchembio724  1
2005 Huffman KE, Corey DR. Major vault protein does not play a role in chemoresistance or drug localization in a non-small cell lung cancer cell line. Biochemistry. 44: 2253-61. PMID 15709737 DOI: 10.1021/bi047948g  1
2004 Kaihatsu K, Huffman KE, Corey DR. Intracellular uptake and inhibition of gene expression by PNAs and PNA-peptide conjugates. Biochemistry. 43: 14340-7. PMID 15533038 DOI: 10.1021/bi048519l  1
2000 Huffman KE, Levene SD, Tesmer VM, Shay JW, Wright WE. Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang. The Journal of Biological Chemistry. 275: 19719-22. PMID 10787419 DOI: 10.1074/jbc.M002843200  1
1999 Huffman KE, Levene SD. DNA-sequence asymmetry directs the alignment of recombination sites in the FLP synaptic complex. Journal of Molecular Biology. 286: 1-13. PMID 9931245 DOI: 10.1006/jmbi.1998.2468  1
1997 Wright WE, Tesmer VM, Huffman KE, Levene SD, Shay JW. Normal human chromosomes have long G-rich telomeric overhangs at one end. Genes & Development. 11: 2801-9. PMID 9353250  1
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