cached image

Richard Mulligan - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Gene therapy
Website:
http://www.hsci.harvard.edu/people/richard-c-mulligan-phd

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Mulligan RC. Development of gene transfer technology. Human Gene Therapy. 25: 995-1002. PMID 25513845 DOI: 10.1089/hum.2014.2543  0.96
2013 Burkhardt UE, Hainz U, Stevenson K, Goldstein NR, Pasek M, Naito M, Wu D, Ho VT, Alonso A, Hammond NN, Wong J, Sievers QL, Brusic A, McDonough SM, Zeng W, ... ... Mulligan RC, et al. Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells. The Journal of Clinical Investigation. 123: 3756-65. PMID 23912587 DOI: 10.1172/JCI69098  0.96
2012 Brusic A, Hainz U, Wadleigh M, Neuberg D, Su M, Canning CM, Deangelo DJ, Stone RM, Lee JS, Mulligan RC, Ritz J, Dranoff G, Sasada T, Wu CJ. Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients. Oncoimmunology. 1: 1095-1103. PMID 23170257 DOI: 10.4161/onci.20954  0.96
2012 Herson S, Hentati F, Rigolet A, Behin A, Romero NB, Leturcq F, Laforêt P, Maisonobe T, Amouri R, Haddad H, Audit M, Montus M, Masurier C, Gjata B, Georger C, ... ... Mulligan RC, et al. A phase I trial of adeno-associated virus serotype 1-γ-sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C. Brain : a Journal of Neurology. 135: 483-92. PMID 22240777 DOI: 10.1093/brain/awr342  0.96
2011 Schwenter F, Zarei S, Luy P, Padrun V, Bouche N, Lee JS, Mulligan RC, Morel P, Mach N. Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy. Cancer Gene Therapy. 18: 553-62. PMID 21566667 DOI: 10.1038/cgt.2011.22  0.96
2011 Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, ... ... Mulligan R, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 470: 359-65. PMID 21307849 DOI: 10.1038/nature09787  0.96
2011 Sanchez CE, Tierney TS, Gale JT, Alavian KN, Sahin A, Lee JS, Mulligan RC, Carter BS. Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation. Journal of Neurosurgery. 114: 672-80. PMID 20950087 DOI: 10.3171/2010.8.JNS091583  0.96
2010 Danos O, Davies K, Lehn P, Mulligan R. The ARRIVE guidelines, a welcome improvement to standards for reporting animal research. The Journal of Gene Medicine. 12: 559-60. PMID 20603891 DOI: 10.1002/jgm.1472  0.96
2010 Wilson AA, Murphy GJ, Hamakawa H, Kwok LW, Srinivasan S, Hovav AH, Mulligan RC, Amar S, Suki B, Kotton DN. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. The Journal of Clinical Investigation. 120: 379-89. PMID 20038801 DOI: 10.1172/JCI36666  0.96
2009 Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. Journal of Neuro-Oncology. 94: 373-82. PMID 19387557 DOI: 10.1007/s11060-009-9889-1  0.96
2009 Yen L, Stockwell BR, Mulligan RC. A mammalian cell-based assay for screening inhibitors of RNA cleavage. Methods in Molecular Biology (Clifton, N.J.). 540: 335-47. PMID 19381571 DOI: 10.1007/978-1-59745-558-9_24  0.96
2008 Kuhnert F, Tam BY, Sennino B, Gray JT, Yuan J, Jocson A, Nayak NR, Mulligan RC, McDonald DM, Kuo CJ. Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 10185-90. PMID 18632559 DOI: 10.1073/pnas.0803194105  0.96
2008 Rodino-Klapac LR, Lee JS, Mulligan RC, Clark KR, Mendell JR. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. Neurology. 71: 240-7. PMID 18525034 DOI: 10.1212/01.wnl.0000306309.85301.e2  0.96
2008 Szentirmai O, Baker CH, Bullain SS, Lin N, Takahashi M, Folkman J, Mulligan RC, Carter BS. Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation. Journal of Neurosurgery. 108: 979-88. PMID 18447716 DOI: 10.3171/JNS/2008/108/5/0979  0.96
2008 Austin KM, Gupta ML, Coats SA, Tulpule A, Mostoslavsky G, Balazs AB, Mulligan RC, Daley G, Pellman D, Shimamura A. Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. The Journal of Clinical Investigation. 118: 1511-8. PMID 18324336 DOI: 10.1172/JCI33764  0.96
2007 Link KH, Guo L, Ames TD, Yen L, Mulligan RC, Breaker RR. Engineering high-speed allosteric hammerhead ribozymes. Biological Chemistry. 388: 779-86. PMID 17655496 DOI: 10.1515/BC.2007.105  0.96
2007 Chan RK, Garfein E, Gigante PR, Liu P, Agha RA, Mulligan R, Orgill DP. Side population hematopoietic stem cells promote wound healing in diabetic mice. Plastic and Reconstructive Surgery. 120: 407-11; discussion 4. PMID 17632341 DOI: 10.1097/01.prs.0000267696.98789.66  0.96
2007 Glodek AM, Le Y, Dykxhoorn DM, Park SY, Mostoslavsky G, Mulligan R, Lieberman J, Beggs HE, Honczarenko M, Silberstein LE. Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells Leukemia. 21: 1723-1732. PMID 17568820 DOI: 10.1038/sj.leu.2404769  0.96
2007 Butler MO, Lee JS, Ansén S, Neuberg D, Hodi FS, Murray AP, Drury L, Berezovskaya A, Mulligan RC, Nadler LM, Hirano N. Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1857-67. PMID 17363542 DOI: 10.1158/1078-0432.CCR-06-1905  0.96
2007 Kaipainen A, Kieran MW, Huang S, Butterfield C, Bielenberg D, Mostoslavsky G, Mulligan R, Folkman J, Panigrahy D. PPARalpha deficiency in inflammatory cells suppresses tumor growth. Plos One. 2: e260. PMID 17327920 DOI: 10.1371/journal.pone.0000260  0.96
2007 Hägerkvist R, Mokhtari D, Lindholm C, Farnebo F, Mostoslavsky G, Mulligan RC, Welsh N, Welsh M. Consequences of Shb and c-Abl interactions for cell death in response to various stress stimuli. Experimental Cell Research. 313: 284-91. PMID 17112510 DOI: 10.1016/j.yexcr.2006.10.011  0.96
2006 Mostoslavsky G, Fabian AJ, Rooney S, Alt FW, Mulligan RC. Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 103: 16406-11. PMID 17062750 DOI: 10.1073/pnas.0608130103  0.96
2006 Murphy GJ, Mostoslavsky G, Kotton DN, Mulligan RC. Exogenous control of mammalian gene expression via modulation of translational termination. Nature Medicine. 12: 1093-9. PMID 16892063 DOI: 10.1038/nm1376  0.96
2006 Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, Jiang S, Nayak NR, Niyak NR, Kuypers FA, Ma L, ... ... Mulligan RC, et al. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nature Medicine. 12: 793-800. PMID 16799557 DOI: 10.1038/nm1428  0.96
2006 Simons JW, Carducci MA, Mikhak B, Lim M, Biedrzycki B, Borellini F, Clift SM, Hege KM, Ando DG, Piantadosi S, Mulligan R, Nelson WG. Phase I/II trial of an allogeneic cellular immunotherapy in hormone-naïve prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3394-401. PMID 16740763 DOI: 10.1158/1078-0432.CCR-06-0145  0.96
2006 Yan CT, Kaushal D, Murphy M, Zhang Y, Datta A, Chen C, Monroe B, Mostoslavsky G, Coakley K, Gao Y, Mills KD, Fazeli AP, Tepsuporn S, Hall G, Mulligan R, et al. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 7378-83. PMID 16670198 DOI: 10.1073/pnas.0601938103  0.96
2006 Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. Rna (New York, N.Y.). 12: 797-806. PMID 16556935 DOI: 10.1261/rna.2300406  0.96
2006 Szentirmai O, Baker CH, Lin N, Szucs S, Takahashi M, Kiryu S, Kung AL, Mulligan RC, Carter BS. Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect. Neurosurgery. 58: 365-72; discussion 3. PMID 16462491 DOI: 10.1227/01.NEU.0000195114.24819.4F  0.96
2006 Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, ... ... Mulligan R, et al. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell. 124: 315-29. PMID 16439206 DOI: 10.1016/j.cell.2005.11.044  0.96
2006 Balazs AB, Fabian AJ, Esmon CT, Mulligan RC. Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood. 107: 2317-21. PMID 16304059 DOI: 10.1182/blood-2005-06-2249  0.96
2005 Levenberg S, Rouwkema J, Macdonald M, Garfein ES, Kohane DS, Darland DC, Marini R, van Blitterswijk CA, Mulligan RC, D'Amore PA, Langer R. Engineering vascularized skeletal muscle tissue. Nature Biotechnology. 23: 879-84. PMID 15965465 DOI: 10.1038/nbt1109  0.96
2005 Kotton DN, Fabian AJ, Mulligan RC. Failure of bone marrow to reconstitute lung epithelium. American Journal of Respiratory Cell and Molecular Biology. 33: 328-34. PMID 15961722 DOI: 10.1165/rcmb.2005-0175RC  0.96
2005 Mostoslavsky G, Kotton DN, Fabian AJ, Gray JT, Lee JS, Mulligan RC. Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 932-40. PMID 15922964 DOI: 10.1016/j.ymthe.2005.01.005  0.96
2005 Kotton DN, Fabian AJ, Mulligan RC. A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity. Blood. 106: 1574-80. PMID 15870171 DOI: 10.1182/blood-2005-03-1017  0.96
2004 Tani K, Azuma M, Nakazaki Y, Oyaizu N, Hase H, Ohata J, Takahashi K, OiwaMonna M, Hanazawa K, Wakumoto Y, Kawai K, Noguchi M, Soda Y, Kunisaki R, Watari K, ... ... Mulligan R, et al. Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 799-816. PMID 15451464 DOI: 10.1016/j.ymthe.2004.07.001  0.96
2004 Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 431: 471-6. PMID 15386015 DOI: 10.1038/nature02844  0.96
2004 Fernandes JR, Duvivier-Kali VF, Keegan M, Hollister-Lock J, Omer A, Su S, Bonner-Weir S, Feng S, Lee JS, Mulligan RC, Weir GC. Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectors. Transplant Immunology. 13: 191-200. PMID 15381202 DOI: 10.1016/j.trim.2004.04.004  0.96
2004 Michurina T, Krasnov P, Balazs A, Nakaya N, Vasilieva T, Kuzin B, Khrushchov N, Mulligan RC, Enikolopov G. Nitric oxide is a regulator of hematopoietic stem cell activity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 241-8. PMID 15294171 DOI: 10.1016/j.ymthe.2004.05.030  0.96
2004 Chang LK, Garcia-Cardeña G, Farnebo F, Fannon M, Chen EJ, Butterfield C, Moses MA, Mulligan RC, Folkman J, Kaipainen A. Dose-dependent response of FGF-2 for lymphangiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 11658-63. PMID 15289610 DOI: 10.1073/pnas.0404272101  0.96
2004 Perron MJ, Stremlau M, Song B, Ulm W, Mulligan RC, Sodroski J. TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 11827-32. PMID 15280539 DOI: 10.1073/pnas.0403364101  0.96
2004 Podar K, Mostoslavsky G, Sattler M, Tai YT, Hayashi T, Catley LP, Hideshima T, Mulligan RC, Chauhan D, Anderson KC. Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells. The Journal of Biological Chemistry. 279: 21658-65. PMID 15010462 DOI: 10.1074/jbc.M305783200  0.96
2004 Matsuzaki Y, Kinjo K, Mulligan RC, Okano H. Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity. 20: 87-93. PMID 14738767 DOI: 10.1016/S1074-7613(03)00354-6  0.96
2003 Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, Dzau VJ. Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation. 108: 2710-5. PMID 14597586 DOI: 10.1161/01.CIR.0000096490.16596.A6  0.96
2003 Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 3343-50. PMID 12947071 DOI: 10.1200/JCO.2003.07.005  0.96
2003 Robert C, Klein C, Cheng G, Kogan A, Mulligan RC, von Andrian UH, Kupper TS. Gene therapy to target dendritic cells from blood to lymph nodes Gene Therapy. 10: 1479-1486. PMID 12900763 DOI: 10.1038/sj.gt.3302008  0.96
2003 Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS. Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Molecular and Cellular Biology. 23: 2395-406. PMID 12640123 DOI: 10.1128/MCB.23.7.2395-2406.2003  0.96
2003 Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, ... ... Mulligan R, et al. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 624-30. PMID 12586798 DOI: 10.1200/JCO.2003.03.091  0.96
2003 Klein C, Nguyen D, Liu CH, Mizoguchi A, Bhan AK, Miki H, Takenawa T, Rosen FS, Alt FW, Mulligan RC, Snapper SB. Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. Blood. 101: 2159-66. PMID 12433691 DOI: 10.1182/blood-2002-05-1423  0.96
2002 Becker CM, Farnebo FA, Iordanescu I, Behonick DJ, Shih MC, Dunning P, Christofferson R, Mulligan RC, Taylor GA, Kuo CJ, Zetter BR. Gene therapy of prostate cancer with the soluble vascular endothelial growth factor receptor Flk1. Cancer Biology & Therapy. 1: 548-53. PMID 12496487 DOI: 10.4161/cbt.1.5.176  0.96
2002 Tseng JF, Mulligan RC. Gene therapy for pancreatic cancer. Surgical Oncology Clinics of North America. 11: 537-69. PMID 12487056 DOI: 10.1016/S1055-3207(02)00023-6  0.96
2002 Tseng JF, Farnebo FA, Kisker O, Becker CM, Kuo CJ, Folkman J, Mulligan RC. Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice. Surgery. 132: 857-65. PMID 12464871 DOI: 10.1067/msy.2002.127680  0.96
2002 Conte MS, Mann MJ, Simosa HF, Rhynhart KK, Mulligan RC. Genetic interventions for vein bypass graft disease: a review. Journal of Vascular Surgery. 36: 1040-52. PMID 12422116 DOI: 10.1067/mva.2002.129112  0.96
2002 Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science (New York, N.Y.). 298: 597-600. PMID 12228720 DOI: 10.1126/science.1072530  0.96
2002 Kawai K, Tani K, Yamashita N, Tomikawa S, Eriguchi M, Fujime M, Okumura K, Kakizoe T, Clift S, Ando D, Mulligan R, Yamauchi A, Noguchi M, Asano S, Akaza H. Advanced renal cell carcinoma treated with granulocyte-macrophage colony-stimulating factor gene therapy: a clinical course of the first Japanese experience. International Journal of Urology : Official Journal of the Japanese Urological Association. 9: 462-6. PMID 12225344 DOI: 10.1046/j.1442-2042.2002.00493.x  0.96
2002 Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Experimental Hematology. 30: 809-15. PMID 12135680 DOI: 10.1016/S0301-472X(02)00835-4  0.96
2002 Niederman TM, Ghogawala Z, Carter BS, Tompkins HS, Russell MM, Mulligan RC. Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 7009-14. PMID 11997459 DOI: 10.1073/pnas.092562399  0.96
2001 Snapper SB, Takeshima F, Antón I, Liu CH, Thomas SM, Nguyen D, Dudley D, Fraser H, Purich D, Lopez-Ilasaca M, Klein C, Davidson L, Bronson R, Mulligan RC, Southwick F, et al. N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nature Cell Biology. 3: 897-904. PMID 11584271 DOI: 10.1038/ncb1001-897  0.96
2001 Faradji RN, Havari E, Chen Q, Gray J, Tornheim K, Corkey BE, Mulligan RC, Lipes MA. Glucose-induced toxicity in insulin-producing pituitary cells that coexpress GLUT2 and glucokinase. Implications for metabolic engineering Journal of Biological Chemistry. 276: 36695-36702. PMID 11443115 DOI: 10.1074/jbc.M102542200  0.96
2001 Kuo CJ, Farnebo F, Yu EY, Christofferson R, Swearingen RA, Carter R, Von Recum HA, Yuan J, Kamihara J, Flynn E, D'Amato R, Folkman J, Mulligan RC. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer Proceedings of the National Academy of Sciences of the United States of America. 98: 4605-4610. PMID 11274374 DOI: 10.1073/pnas.081615298  0.96
2001 Kuo CJ, LaMontagne KR, Garcia-Cardeña G, Ackley BD, Kalman D, Park S, Christofferson R, Kamihara J, Ding YH, Lo KM, Gillies S, Folkman J, Mulligan RC, Javaherian K. Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain. The Journal of Cell Biology. 152: 1233-46. PMID 11257123 DOI: 10.1083/jcb.152.6.1233  0.96
2001 Lundberg C, Jungles SJ, Mulligan RC. Direct delivery of leptin to the hypothalamus using recombinant adeno-associated virus vectors results in increased therapeutic efficacy. Nature Biotechnology. 19: 169-72. PMID 11175734 DOI: 10.1038/84448  0.96
2001 Snitkovsky S, Niederman TM, Mulligan RC, Young JA. Targeting avian leukosis virus subgroup A vectors by using a TVA-VEGF bridge protein. Journal of Virology. 75: 1571-5. PMID 11152532 DOI: 10.1128/JVI.75.3.1571-1575.2001  0.96
2000 Snitkovsky S, Niederman TM, Carter BS, Mulligan RC, Young JA. A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptor. Journal of Virology. 74: 9540-5. PMID 11000224 DOI: 10.1128/JVI.74.20.9540-9545.2000  0.96
2000 Storms RW, Goodell MA, Fisher A, Mulligan RC, Smith C. Hoechst dye efflux reveals a novel CD7+CD34- lymphoid progenitor in human umbilical cord blood Blood. 96: 2125-2133. PMID 10979957  0.96
2000 Tani K, Nakazaki Y, Hase H, Takahashi K, Azuma M, Ohata J, Kitamura R, Komine F, Oiwa M, Masunaga A, Maekawa T, Satoh N, Adachi D, Soda Y, Machida U, ... ... Mulligan R, et al. Progress reports on immune gene therapy for stage IV renal cell cancer using lethally irradiated granulocyte-macrophage colony-stimulating factor-transduced autologous renal cancer cells Cancer Chemotherapy and Pharmacology. 46: S73-S76. PMID 10950152  0.96
2000 Nelson WG, Simons JW, Mikhak B, Chang JF, DeMarzo AM, Carducci MA, Kim M, Weber CE, Baccala AA, Goeman MA, Clift SM, Ando DG, Levitsky HI, Cohen LK, Sanda MG, ... Mulligan RC, et al. Cancer cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer as vaccines for the treatment of genitourinary malignancies. Cancer Chemotherapy and Pharmacology. 46: S67-72. PMID 10950151  0.96
2000 Dahl AM, Klein C, Andres PG, London CA, Lodge MP, Mulligan RC, Abbas AK. Expression of Bcl-X(L) restores cell survival, but not proliferation and effector differentiation, in CD28-deficient T lymphocytes Journal of Experimental Medicine. 191: 2031-2037. PMID 10859328 DOI: 10.1084/jem.191.12.2031  0.96
2000 Klein C, Bueler H, Mulligan RC. Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines Journal of Experimental Medicine. 191: 1699-1708. PMID 10811863 DOI: 10.1084/jem.191.10.1699  0.96
2000 Feng D, Nagy JA, Brekken RA, Pettersson A, Manseau EJ, Pyne K, Mulligan R, Thorpe PE, Dvorak HF, Dvorak AM. Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (FLK-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF- expressing tumors and adenoviral vectors Journal of Histochemistry and Cytochemistry. 48: 545-555. PMID 10727296  0.96
2000 Pettersson A, Nagy JA, Brown LF, Sundberg C, Morgan E, Jungles S, Carter R, Krieger JE, Manseau EJ, Harvey VS, Eckelhoefer IA, Feng D, Dvorak AM, Mulligan RC, Dvorak HF. Heterogeneity of the angiogenic response induced in different normal adult tissues by vascular permeability factor/vascular endothelial growth factor. Laboratory Investigation; a Journal of Technical Methods and Pathology. 80: 99-115. PMID 10653008  0.96
2000 Sieminski A, Padera R, Blunk T, Mulligan R, Langer R, Gooch K. Tissue-engineered microvascular networks for gene therapy Annals of Biomedical Engineering. 28: S-24.  0.96
2000 Snapper SB, Nguyen D, Stockton B, Bozza P, Laouar A, Liu CH, Rosen FS, Mulligan RC, Alt FW, Von Andrian UH, Klein C. Wasp-deficiency causes impaired migration of t-cells, dendritic cells, and neutrophils Blood. 96: 23a.  0.96
1999 Simons JW, Mikhak B, Chang JF, DeMarzo AM, Carducci MA, Lim M, Weber CE, Baccala AA, Goemann MA, Clift SM, Ando DG, Levitsky HI, Cohen LK, Sanda MG, Mulligan RC, et al. Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer. Cancer Research. 59: 5160-8. PMID 10537292  0.96
1999 Gussoni E, Soneoka Y, Strickland CD, Buzney EA, Khan MK, Flint AF, Kunkel LM, Mulligan RC. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature. 401: 390-4. PMID 10517639 DOI: 10.1038/43919  0.96
1999 Feng S, Quickel RR, Hollister-Lock J, McLeod M, Bonner-Weir S, Mulligan RC, Weir GC. Prolonged xenograft survival of islets infected with small doses of adenovirus expressing CTLA4Ig Transplantation. 67: 1607-1613. PMID 10401769 DOI: 10.1097/00007890-199906270-00016  0.96
1999 Zehntner S, Townsend W, Parkes J, Schmidt C, Down M, Bell J, Mulligan R, O'Rourke M, Ellem K, Thomas R. Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy Pathology. 31: 116-122. PMID 10399166 DOI: 10.1080/003130299105296  0.96
1999 Rebel VI, Tanaka M, Lee JS, Hartnett S, Pulsipher M, Nathan DG, Mulligan RC, Sieff CA. One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Blood. 93: 2217-24. PMID 10090930  0.96
1998 Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC, Hodi FS, Liebster L, Lam P, Mentzer S, Singer S, Tanabe KK, Cosimi AB, Duda R, Sober A, ... ... Mulligan RC, et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma Proceedings of the National Academy of Sciences of the United States of America. 95: 13141-13146. PMID 9789055 DOI: 10.1073/pnas.95.22.13141  0.96
1998 Pulsipher M, Kupfer GM, Naf D, Suliman A, Lee JS, Jakobs P, Grompe M, Joenje H, Sieff C, Guinan E, Mulligan R, D'Andrea AD. Subtyping analysis of Fanconi anemia by immunoblotting and retroviral gene transfer Molecular Medicine. 4: 468-479. PMID 9713825  0.96
1998 Sonderbye L, Feng S, Yacoubian S, Buehler H, Ahsan N, Mulligan R, Langhoff E. In vivo and in vitro modulation of immune stimulatory capacity of primary dendritic cells by adenovirus-mediated gene transduction Experimental and Clinical Immunogenetics. 15: 100-111. PMID 9691204 DOI: 10.1159/000019060  0.96
1998 Gainsford T, Roberts AW, Kimura S, Metcalf D, Dranoff G, Mulligan RC, Begley CG, Robb L, Alexander WS. Cytokine production and function in c-mpl-deficient mice: No physiologic role for interleukin-3 in residual megakaryocyte and platelet production Blood. 91: 2745-2752. PMID 9531584  0.96
1998 Lantz CS, Boeslger J, Song CH, Mach N, Kobayashi T, Mulligan RC, Nawa Y, Dranoff G, Galli SJ. Role for interleukin-3 in mast cell and basophil development and in immunity to parasites Nature. 392: 90-93. PMID 9510253 DOI: 10.1038/32190  0.96
1998 McArthur JG, Mulligan RC. Induction of protective anti-tumor immunity by gene-modified dendritic cells Journal of Immunotherapy. 21: 41-47. PMID 9456435 DOI: 10.1097/00002371-199801000-00005  0.96
1998 Mach N, Lantz CS, Galli SJ, Reznikoff G, Mihm M, Small C, Granstein R, Beissert S, Sadelain M, Mulligan RC, Dranoff G. Involvement of interleukin-3 in delayed-type hypersensitivity. Blood. 91: 778-83. PMID 9446636  0.96
1998 Lantz CS, Boesiger J, Song CH, Kimura K, Mach N, Kobayashi T, Mulligan RC, Nawa Y, Dranoff G, Galli SJ. Role for interleukin-3 (IL-3) in mast cell and basophil development and parasite immunity revealed by IL-3-deficient mice Faseb Journal. 12: A894.  0.96
1997 Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, Grupp SA, Sieff CA, Mulligan RC, Johnson RP. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nature Medicine. 3: 1337-45. PMID 9396603 DOI: 10.1038/nm1297-1337  0.96
1997 Lindemann D, Patriquin E, Feng S, Mulligan RC. Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo Molecular Medicine. 3: 466-476. PMID 9260158  0.96
1997 Ellem KA, O'Rourke MG, Johnson GR, Parry G, Misko IS, Schmidt CW, Parsons PG, Burrows SR, Cross S, Fell A, Li CL, Bell JR, Dubois PJ, Moss DJ, Good MF, ... ... Mulligan RC, et al. A case report: immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy. Cancer Immunology, Immunotherapy : Cii. 44: 10-20. PMID 9111579 DOI: 10.1007/s002620050349  0.96
1997 Simons JW, Jaffee EM, Weber CE, Levitsky HI, Nelson WG, Carducci MA, Lazenby AJ, Cohen LK, Finn CC, Clift SM, Hauda KM, Beck LA, Leiferman KM, Owens AH, Piantadosi S, ... ... Mulligan RC, et al. Bioactivity of autologous irradiated renal cell carcinoma vaccines generated by ex vivo granulocyte-macrophage colony-stimulating factor gene transfer. Cancer Research. 57: 1537-46. PMID 9108457  0.96
1997 Lieschke GJ, Rao PK, Gately MK, Mulligan RC. Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo Nature Biotechnology. 15: 35-40. PMID 9035103  0.96
1997 Dranoff G, Soiffer R, Lynch T, Mihm M, Jung K, Kolesar K, Liebster L, Lam P, Duda R, Mentzer S, Singer S, Tanabe K, Johnson R, Sober A, Bhan A, ... ... Mulligan RC, et al. A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor Human Gene Therapy. 8: 111-121,122. PMID 8990000  0.96
1997 Soiffer DG, Lynch R, Mihm T, Jung M, Kolesar K, Liebster K, Lam L, Duda P, Mentzer R, Singer S, Tanabe S, Johnson K, Sober R, Bhan A, Clift A, ... ... Mulligan RC, et al. A phase i study of vaccination with autologous, lethally irradiated melanoma cells engineered to secrete human gm-csf: A progress report Faseb Journal. 11: A997.  0.96
1996 Naito T, Yokoyama H, Moore KJ, Dranoff G, Mulligan RC, Kelley VR. A gene transfer system establishes interleukin-6 neither promotes nor suppresses renal injury American Journal of Physiology. 271: F603-F609. PMID 8853422  0.96
1996 Yokoyama H, Naito T, Dranoff G, Mulligan RC, Rubin-Kelley V. Gene transfer of macrophage growth factors into the kidney of lpr mice initiates renal injury Contributions to Nephrology. 118: 94-99. PMID 8744045  0.96
1996 Tant K, Hibino H, Wu S, Ikebuchi K, Suziiki S, Tanioka K, Sugimoto Y, Toio VA, Nakihata T, Saitoh I, Mulligan RC, Asano S. Characterization of hematopoiet1c stem cells of common marmoset to establish the precunical primate model system for human gene therapy Experimental Hematology. 24: 1060.  0.96
1995 Sadelain M, Wang CH, Antoniou M, Grosveld F, Mulligan RC. Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 6728-32. PMID 7624311  0.32
1993 Silver DP, Spanopoulou E, Mulligan RC, Baltimore D. Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. Proceedings of the National Academy of Sciences of the United States of America. 90: 6100-4. PMID 8327489  0.44
1992 Cone RD, Mulligan RC. High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. 1984. Biotechnology (Reading, Mass.). 24: 420-4. PMID 1384843  0.96
1992 Wilson JM, Grossman M, Thompson AR, Lupassikis C, Rosenberg A, Potts JT, Kronenberg HM, Mulligan RC, Nussbaum SR. Somatic gene transfer in the development of an animal model for primary hyperparathyroidism. Endocrinology. 130: 2947-54. PMID 1315263 DOI: 10.1210/endo.130.5.1315263  0.6
1990 Wilson JM, Danos O, Grossman M, Raulet DH, Mulligan RC. Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 439-43. PMID 2296599  0.96
1990 Wilson JM, Chowdhury NR, Grossman M, Wajsman R, Epstein A, Mulligan RC, Chowdhury JR. Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 8437-41. PMID 2236051  0.96
1989 Wilson JM, Birinyi LK, Salomon RN, Libby P, Callow AD, Mulligan RC. Implantation of vascular grafts lined with genetically modified endothelial cells. Science (New York, N.Y.). 244: 1344-6. PMID 2734614  0.52
1989 Wilson JM, Birinyi LK, Salomon RN, Libby P, Callow AD, Mulligan RC. Genetically modified endothelial cells in the treatment of human diseases. Transactions of the Association of American Physicians. 102: 139-47. PMID 2638522  0.52
1989 Lenardo MJ, Staudt L, Robbins P, Kuang A, Mulligan RC, Baltimore D. Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science (New York, N.Y.). 243: 544-6. PMID 2536195  0.44
1988 Danos O, Mulligan RC. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proceedings of the National Academy of Sciences of the United States of America. 85: 6460-4. PMID 3413107  0.96
1988 Weber-Benarous A, Cone RD, London IM, Mulligan RC. Retroviral-mediated transfer and expression of human beta-globin genes in cultured murine and human erythroid cells. The Journal of Biological Chemistry. 263: 6142-5. PMID 3162912  0.96
1988 Dostatni N, Yaniv M, Danos O, Mulligan RC. Use of retroviral vectors for mapping of splice sites in cottontail rabbit papillomavirus. The Journal of General Virology. 69: 3093-100. PMID 2848927  0.96
1988 Wilson JM, Jefferson DM, Chowdhury JR, Novikoff PM, Johnston DE, Mulligan RC. Retrovirus-mediated transduction of adult hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 85: 3014-8. PMID 2834728  0.96
1988 Wilson JM, Johnston DE, Jefferson DM, Mulligan RC. Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. Proceedings of the National Academy of Sciences of the United States of America. 85: 4421-5. PMID 2454468  0.96
1987 Williams DA, Hsieh K, DeSilva A, Mulligan RC. Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow. The Journal of Experimental Medicine. 166: 210-8. PMID 3298524  0.96
1987 Cone RD, Reilly EB, Eisen HN, Mulligan RC. Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. Science (New York, N.Y.). 236: 954-7. PMID 3107128  0.96
1987 Cone RD, Weber-Benarous A, Baorto D, Mulligan RC. Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector. Molecular and Cellular Biology. 7: 887-97. PMID 3029570  0.96
1986 Choudary PV, Barranger JA, Tsuji S, Mayor J, LaMarca ME, Cepko CL, Mulligan RC, Ginns EI. Retrovirus-mediated transfer of the human glucocerebrosidase gene to Gaucher fibroblasts. Molecular Biology & Medicine. 3: 293-9. PMID 3736391  0.96
1986 Williams DA, Orkin SH, Mulligan RC. Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 83: 2566-70. PMID 3458218  0.96
1986 Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318  0.96
1986 Jat PS, Cepko CL, Mulligan RC, Sharp PA. Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Molecular and Cellular Biology. 6: 1204-17. PMID 3023876  0.96
1986 Danos O, Mulligan RC, Yaniv M. Production of spliced DNA copies of the cottontail rabbit papillomavirus genome in a retroviral vector. Ciba Foundation Symposium. 120: 68-82. PMID 3013527  0.96
1986 Uchida N, Cone RD, Freeman GJ, Mulligan RC, Cantor H. High efficiency gene transfer into murine T cell clones using a retroviral vector. Journal of Immunology (Baltimore, Md. : 1950). 136: 1876-9. PMID 3005404  0.96
1985 Roberts BE, Miller JS, Kimelman D, Cepko CL, Lemischka IR, Mulligan RC. Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression. Journal of Virology. 56: 404-13. PMID 4057356  0.96
1984 Cepko CL, Roberts BE, Mulligan RC. Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell. 37: 1053-62. PMID 6331674 DOI: 10.1016/0092-8674(84)90440-9  0.96
1984 Cone RD, Mulligan RC. High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. Proceedings of the National Academy of Sciences of the United States of America. 81: 6349-53. PMID 6093098  0.96
1984 Hellerman JG, Cone RC, Potts JT, Rich A, Mulligan RC, Kronenberg HM. Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone. Proceedings of the National Academy of Sciences of the United States of America. 81: 5340-4. PMID 6089196  0.6
1984 Williams DA, Lemischka IR, Nathan DG, Mulligan RC. Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature. 310: 476-80. PMID 6087158 DOI: 10.1038/310476a0  0.96
1983 Mann R, Mulligan RC, Baltimore D. Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell. 33: 153-9. PMID 6678608  0.44
1981 Subramani S, Mulligan R, Berg P. Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. Molecular and Cellular Biology. 1: 854-64. PMID 9279398  1
1981 Mulligan RC, Berg P. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 78: 2072-6. PMID 7017722  1
1981 Lee F, Mulligan R, Berg P, Ringold G. Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. Nature. 294: 228-32. PMID 6272123  1
1981 Mulligan RC, Berg P. Factors governing the expression of a bacterial gene in mammalian cells. Molecular and Cellular Biology. 1: 449-59. PMID 6100966  1
1980 Mulligan RC, Berg P. Expression of a bacterial gene in mammalian cells. Science (New York, N.Y.). 209: 1422-7. PMID 6251549  1
1979 Mulligan RC, Howard BH, Berg P. Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome. Nature. 277: 108-14. PMID 215915  1
1976 Rozenblatt S, Mulligan RC, Gorecki M, Roberts BE, Rich A. Direct biochemical mapping of eukaryotic viral DNA by means of a linked transcription-translation cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 73: 2747-51. PMID 183208  0.96
1975 Roberts BE, Gorecki M, Mulligan RC, Danna KJ, Rozenblatt S, Rich A. Simian virus 40 DNA directs synthesis of authentic viral polypeptides in a linked transcription-translation cell-free system. Proceedings of the National Academy of Sciences of the United States of America. 72: 1922-6. PMID 168582 DOI: 10.1073/pnas.72.5.1922  0.96
1974 Kemper B, Habener JF, Mulligan RC, Potts JT, Rich A. Pre-proparathyroid hormone: a direct translation product of parathyroid messenger RNA. Proceedings of the National Academy of Sciences of the United States of America. 71: 3731-5. PMID 4530333  0.6
Show low-probability matches.