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Christopher G. Mayne, Ph.D. - Publications

Affiliations: 
2011 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mayne CG, Toy W, Carlson KE, Bhatt T, Fanning SW, Greene GL, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA, Tajkhorshid E. Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular Cancer Research : McR. PMID 34021071 DOI: 10.1158/1541-7786.MCR-20-1017  0.584
2020 Li Y, Coons LA, Houtman R, Carlson KE, Martin TA, Mayne CG, Melchers D, Jefferson TB, Ramsey JT, Katzenellenbogen JA, Korach KS. A mutant form of ERα associated with estrogen insensitivity affects the coupling between ligand binding and coactivator recruitment. Science Signaling. 13. PMID 32963012 DOI: 10.1126/scisignal.aaw4653  0.539
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/Elife.37161  0.597
2018 Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/Acschembio.8B00877  0.671
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 30185950 DOI: 10.1038/S41568-018-0053-0  0.501
2018 Speltz TE, Mayne CG, Fanning SW, Siddiqui Z, Tajkhorshid E, Greene GL, Moore TW. A "cross-stitched" peptide with improved helicity and proteolytic stability. Organic & Biomolecular Chemistry. PMID 29725689 DOI: 10.1039/C8Ob00790J  0.552
2018 Katzenellenbogen JA, Mayne CG, Katzenellenbogen BS, Greene GL, Chandarlapaty S. Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance. Nature Reviews. Cancer. PMID 29662238 DOI: 10.1038/S41568-018-0001-Z  0.631
2018 Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, et al. Author response: The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells Elife. DOI: 10.7554/Elife.37161.024  0.499
2018 Speltz TE, Danes JM, Fanning SW, Mayne CG, Tajkhorshid E, Greene GL, Frasor JM, Moore TW. Abstract 1810: Stapled peptide inhibitors of mutant estrogen receptor/coactivator interactions Cancer Research. 78: 1810-1810. DOI: 10.1158/1538-7445.Am2018-1810  0.539
2017 Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/Acs.Jmedchem.7B00585  0.645
2017 Arcario MJ, Mayne CG, Tajkhorshid E. A membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus Ion Channel. The Journal of Biological Chemistry. PMID 28420728 DOI: 10.1074/Jbc.M117.780197  0.309
2017 Toy W, Carlson KE, Martin TA, Mayne CG, Fanning SW, Razavi P, Baselga J, Shen Y, Greene G, Katzenellenbogen B, Katzenellenbogen J, Chandarlapaty S. Abstract 999: ESR1 mutations activate and confer hormone resistance via distinct mechanisms Endocrinology. 77: 999-999. DOI: 10.1158/1538-7445.Am2017-999  0.486
2016 Madak-Erdogan Z, Kim SH, Gong P, Zhao YC, Zhang H, Chambliss KL, Carlson KE, Mayne CG, Shaul PW, Korach KS, Katzenellenbogen JA, Katzenellenbogen BS. Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues. Science Signaling. 9: ra53. PMID 27221711 DOI: 10.1126/Scisignal.Aad8170  0.542
2016 Speltz TE, Fanning SW, Mayne CG, Fowler C, Tajkhorshid E, Greene GL, Moore TW. Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction. Angewandte Chemie (International Ed. in English). PMID 26928945 DOI: 10.1002/Anie.201510557  0.556
2016 Hosseinzadeh P, Mirts EN, Pfister TD, Gao YG, Mayne C, Robinson H, Tajkhorshid E, Lu Y. Enhancing Mn(II)-binding and manganese peroxidase activity in a designed cytochrome c peroxidase through fine-tuning secondary sphere interactions. Biochemistry. PMID 26885726 DOI: 10.1021/Acs.Biochem.5B01299  0.354
2016 Fanning SW, Mayne CG, Dharmarajan V, Carlson KE, Martin TA, Novick SJ, Toy W, Green B, Panchamukhi S, Katzenellenbogen BS, Tajkhorshid E, Griffin PR, Shen Y, Chandarlapaty S, Katzenellenbogen JA, et al. Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation. Elife. 5. PMID 26836308 DOI: 10.7554/Elife.12792  0.594
2016 West D, Hosfield D, Mayne C, Skor M, Styke S, Pierce C, Kocherginsky M, Hunt H, Fleming G, Szmulewitz R, Tajkhorshid E, Greene G, Conzen S. Abstract PD3-02: Second-generation selective glucocorticoid receptor modulators in triple-negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-Pd3-02  0.461
2016 Fanning SW, Dharmarajan V, Mayne CG, Toy W, Carlson KE, Martin TA, Nowak J, Nwachukwu J, Hosfield DJ, Tajkhorshid E, Chandarlapaty S, Griffin P, Shen Y, Katzenellenbogen JA, Greene GL. Abstract 4854: Bazedoxifene inhibits ESR1 somatic mutants with improved potency compared to tamoxifene and raloxifene Cancer Research. 76: 4854-4854. DOI: 10.1158/1538-7445.Am2016-4854  0.598
2016 Moore TW, Speltz TE, Fanning SW, Mayne CG, Frasor J, Greene GL, Tajkhorshid E. Abstract 3104: Stapled peptide inhibitors of the estrogen receptor/steroid receptor coactivator interaction Cancer Research. 76: 3104-3104. DOI: 10.1158/1538-7445.Am2016-3104  0.525
2016 Speltz TE, Fanning SW, Mayne CG, Fowler C, Tajkhorshid E, Greene GL, Moore TW. Inside Cover: Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction (Angew. Chem. Int. Ed. 13/2016) Angewandte Chemie International Edition. 55: 4104-4104. DOI: 10.1002/Anie.201601641  0.573
2016 Speltz TE, Fanning SW, Mayne CG, Fowler C, Tajkhorshid E, Greene GL, Moore TW. Innentitelbild: Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction (Angew. Chem. 13/2016) Angewandte Chemie. 128: 4174-4174. DOI: 10.1002/Ange.201601641  0.575
2015 Yasui N, Mayne CG, Katzenellenbogen JA. Preparation of o-Fluorophenols from Nonaromatic Precursors: Mechanistic Considerations for Adaptation to Fluorine-18 Radiolabeling. Organic Letters. PMID 26536250 DOI: 10.1021/Acs.Orglett.5B02640  0.392
2015 Durrant JD, Carlson KE, Martin TA, Offutt TL, Mayne CG, Katzenellenbogen JA, Amaro RE. Neural-Network Scoring Functions Identify Structurally Novel Estrogen-Receptor Ligands. Journal of Chemical Information and Modeling. 55: 1953-61. PMID 26286148 DOI: 10.1021/Acs.Jcim.5B00241  0.514
2015 Kim SH, Madak-Erdogan Z, Bae SC, Carlson KE, Mayne CG, Granick S, Katzenellenbogen BS, Katzenellenbogen JA. Ligand Accessibility and Bioactivity of a Hormone-Dendrimer Conjugate Depend on pH and pH History. Journal of the American Chemical Society. PMID 26186415 DOI: 10.1021/Jacs.5B05952  0.467
2015 Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07  0.667
2012 Mayne CG, Katzenellenbogen JA, Tajkhorshid E. Characterizing Structural and Dynamical Impacts of Agonist- and Antsgonist-Stabilized Mutants of the Estrogen Receptor Biophysical Journal. 102: 457a. DOI: 10.1016/J.Bpj.2011.11.2508  0.579
2010 Zhou HB, Lee JH, Mayne CG, Carlson KE, Katzenellenbogen JA. Imaging progesterone receptor in breast tumors: synthesis and receptor binding affinity of fluoroalkyl-substituted analogues of tanaproget. Journal of Medicinal Chemistry. 53: 3349-60. PMID 20355713 DOI: 10.1021/Jm100052K  0.57
2010 Moore TW, Mayne CG, Katzenellenbogen JA. Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs). Molecular Endocrinology (Baltimore, Md.). 24: 683-95. PMID 19933380 DOI: 10.1210/Me.2009-0362  0.647
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