Nicholas T. Ingolia, Ph.D. - Publications

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA 
 2006 Harvard University, Cambridge, MA, United States 
Area:
Molecular basis and physiological roles of the Translational control of gene expression through global and genome-wide analyses

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen M, Asanuma M, Takahashi M, Shichino Y, Mito M, Fujiwara K, Saito H, Floor SN, Ingolia NT, Sodeoka M, Dodo K, Ito T, Iwasaki S. Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A. Cell Chemical Biology. PMID 33296667 DOI: 10.1016/j.chembiol.2020.11.008  1
2020 Matsuki Y, Matsuo Y, Nakano Y, Iwasaki S, Yoko H, Udagawa T, Li S, Saeki Y, Yoshihisa T, Tanaka K, Ingolia NT, Inada T. Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome. Scientific Reports. 10: 19669. PMID 33184379 DOI: 10.1038/s41598-020-76239-3  1
2019 Padrón A, Iwasaki S, Ingolia NT. Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules. Molecular Cell. 75: 875-887.e5. PMID 31442426 DOI: 10.1016/j.molcel.2019.07.030  1
2019 McGeachy AM, Meacham ZA, Ingolia NT. An Accessible Continuous-Culture Turbidostat for Pooled Analysis of Complex Libraries. Acs Synthetic Biology. 8: 844-856. PMID 30908907 DOI: 10.1021/acssynbio.8b00529  0.72
2018 Iwasaki S, Iwasaki W, Takahashi M, Sakamoto A, Watanabe C, Shichino Y, Floor SN, Fujiwara K, Mito M, Dodo K, Sodeoka M, Imataka H, Honma T, Fukuzawa K, Ito T, ... Ingolia NT, et al. The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA. Molecular Cell. PMID 30595437 DOI: 10.1016/j.molcel.2018.11.026  1
2018 Ingolia NT, Hussmann JA, Weissman JS. Ribosome Profiling: Global Views of Translation. Cold Spring Harbor Perspectives in Biology. PMID 30037969 DOI: 10.1101/cshperspect.a032698  0.96
2017 Matsuo Y, Ikeuchi K, Saeki Y, Iwasaki S, Schmidt C, Udagawa T, Sato F, Tsuchiya H, Becker T, Tanaka K, Ingolia NT, Beckmann R, Inada T. Ubiquitination of stalled ribosome triggers ribosome-associated quality control. Nature Communications. 8: 159. PMID 28757607 DOI: 10.1038/s41467-017-00188-1  1
2017 Iwasaki S, Ingolia NT. The Growing Toolbox for Protein Synthesis Studies. Trends in Biochemical Sciences. PMID 28566214 DOI: 10.1016/j.tibs.2017.05.004  1
2017 Ishikawa K, Makanae K, Iwasaki S, Ingolia NT, Moriya H. Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes. Plos Genetics. 13: e1006554. PMID 28121980 DOI: 10.1371/journal.pgen.1006554  1
2016 Mills EW, Wangen J, Green R, Ingolia NT. Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets. Cell Reports. 17: 1-10. PMID 27681415 DOI: 10.1016/j.celrep.2016.08.088  1
2016 Sen ND, Zhou F, Harris MS, Ingolia NT, Hinnebusch AG. eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601676 DOI: 10.1073/pnas.1612398113  1
2016 Iwasaki S, Ingolia NT. PROTEIN TRANSLATION. Seeing translation. Science (New York, N.Y.). 352: 1391-2. PMID 27313023 DOI: 10.1126/science.aag1039  1
2016 Iwasaki S, Floor SN, Ingolia NT. Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor. Nature. PMID 27309803 DOI: 10.1038/nature17978  1
2016 Newman ZR, Young JM, Ingolia NT, Barton GM. Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9. Proceedings of the National Academy of Sciences of the United States of America. PMID 26903634 DOI: 10.1073/pnas.1518976113  1
2016 McGeachy AM, Ingolia NT. Starting too soon: upstream reading frames repress downstream translation. The Embo Journal. PMID 26896443 DOI: 10.15252/embj.201693946  0.72
2015 Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS. A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Molecular Cell. 60: 816-27. PMID 26638175 DOI: 10.1016/j.molcel.2015.11.013  1
2015 Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, Fedrigo I, Ingolia NT, Rape M. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 525: 523-7. PMID 26399832 DOI: 10.1038/nature14978  1
2015 Sidrauski C, McGeachy AM, Ingolia NT, Walter P. The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly. Elife. 4. PMID 25719440 DOI: 10.7554/eLife.05033  1
2015 Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO. Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proceedings of the National Academy of Sciences of the United States of America. 112: 1607-12. PMID 25605929 DOI: 10.1073/pnas.1421419112  1
2015 Sen ND, Zhou F, Ingolia NT, Hinnebusch AG. Genome-wide analysis of translational efficiency reveals distinct but overlapping functions of yeast DEAD-box RNA helicases Ded1 and eIF4A Genome Research. 25: 1196-1205. DOI: 10.1101/gr.191601.115  1
2015 Ori A, Toyama BH, Harris MS, Bock T, Iskar M, Bork P, Ingolia NT, Hetzer MW, Beck M. Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats Cell Systems. 1: 224-237. DOI: 10.1016/j.cels.2015.08.012  1
2014 Pop C, Rouskin S, Ingolia NT, Han L, Phizicky EM, Weissman JS, Koller D. Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation. Molecular Systems Biology. 10: 770. PMID 25538139 DOI: 10.15252/msb.20145524  1
2014 Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH, Noren Hooten N, Evans MK, ... ... Ingolia NT, et al. PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity. Nature Communications. 5: 5248. PMID 25366541 DOI: 10.1038/ncomms6248  1
2014 Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS. Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Reports. 8: 1365-79. PMID 25159147 DOI: 10.1016/j.celrep.2014.07.045  1
2014 Castañeda J, Genzor P, van der Heijden GW, Sarkeshik A, Yates JR, Ingolia NT, Bortvin A. Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice. The Embo Journal. 33: 1999-2019. PMID 25063675 DOI: 10.15252/embj.201386855  1
2014 Brubaker SW, Gauthier AE, Mills EW, Ingolia NT, Kagan JC. A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity. Cell. 156: 800-11. PMID 24529381 DOI: 10.1016/j.cell.2014.01.021  1
2013 Toyama BH, Savas JN, Park SK, Harris MS, Ingolia NT, Yates JR, Hetzer MW. Identification of long-lived proteins reveals exceptional stability of essential cellular structures. Cell. 154: 971-82. PMID 23993091 DOI: 10.1016/j.cell.2013.07.037  1
2013 Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. Genome-wide annotation and quantitation of translation by ribosome profiling. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 4.18. PMID 23821443 DOI: 10.1002/0471142727.mb0418s103  1
2013 Guttman M, Russell P, Ingolia NT, Weissman JS, Lander ES. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell. 154: 240-51. PMID 23810193 DOI: 10.1016/j.cell.2013.06.009  1
2013 Thorburn RR, Gonzalez C, Brar GA, Christen S, Carlile TM, Ingolia NT, Sauer U, Weissman JS, Amon A. Aneuploid yeast strains exhibit defects in cell growth and passage through START. Molecular Biology of the Cell. 24: 1274-89. PMID 23468524 DOI: 10.1091/mbc.E12-07-0520  1
2012 Nakatsu F, Baskin JM, Chung J, Tanner LB, Shui G, Lee SY, Pirruccello M, Hao M, Ingolia NT, Wenk MR, De Camilli P. PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity. The Journal of Cell Biology. 199: 1003-16. PMID 23229899 DOI: 10.1083/jcb.201206095  1
2012 Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. Decoding human cytomegalovirus. Science (New York, N.Y.). 338: 1088-93. PMID 23180859 DOI: 10.1126/science.1227919  1
2012 Ingolia NT, Brar GA, Rouskin S, McGeachy AM, Weissman JS. The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments. Nature Protocols. 7: 1534-50. PMID 22836135 DOI: 10.1038/nprot.2012.086  1
2012 Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY, Stumpf CR, Christensen C, Bonham MJ, Wang S, Ren P, Martin M, Jessen K, Feldman ME, et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis. Nature. 485: 55-61. PMID 22367541 DOI: 10.1038/nature10912  0.96
2012 Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS. High-resolution view of the yeast meiotic program revealed by ribosome profiling. Science (New York, N.Y.). 335: 552-7. PMID 22194413 DOI: 10.1126/science.1215110  1
2011 Ingolia NT, Lareau LF, Weissman JS. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell. 147: 789-802. PMID 22056041 DOI: 10.1016/j.cell.2011.10.002  1
2011 Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature. 476: 88-91. PMID 21814281 DOI: 10.1038/nature10245  1
2011 Fordyce P, Ingolia N. Integrating systems biology data to yield functional genomics insights. Genome Biology. 12: 302. PMID 21247510 DOI: 10.1186/gb-2011-12-1-302  1
2011 Takacs JE, Neary TB, Ingolia NT, Saini AK, Martin-Marcos P, Pelletier J, Hinnebusch AG, Lorsch JR. Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery. Rna (New York, N.Y.). 17: 439-52. PMID 21220547 DOI: 10.1261/rna.2475211  1
2010 Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 466: 835-40. PMID 20703300 DOI: 10.1038/nature09267  1
2010 Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D. Molecular basis of infrared detection by snakes. Nature. 464: 1006-11. PMID 20228791 DOI: 10.1038/nature08943  1
2009 Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/nmeth.1330  1
2009 Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science (New York, N.Y.). 324: 218-23. PMID 19213877 DOI: 10.1126/science.1168978  1
2008 Ingolia NT, Weissman JS. Systems biology: Reverse engineering the cell. Nature. 454: 1059-62. PMID 18756243 DOI: 10.1038/4541059a  1
2007 Ingolia NT, Murray AW. Positive-feedback loops as a flexible biological module. Current Biology : Cb. 17: 668-77. PMID 17398098 DOI: 10.1016/j.cub.2007.03.016  1
2004 Ingolia NT, Murray AW. The ups and downs of modeling the cell cycle. Current Biology : Cb. 14: R771-7. PMID 15380091 DOI: 10.1016/j.cub.2004.09.018  1
2002 Ingolia NT, Murray AW. Signal transduction. History matters. Science (New York, N.Y.). 297: 948-9. PMID 12169717 DOI: 10.1126/science.1075222  1
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