| Year |
Citation |
Score |
| 2018 |
Boezio AA, Andrews K, Boezio C, Chu-Moyer M, Copeland KW, DiMauro EF, Foti RS, Fremeau RT, Gao H, Geuns-Meyer S, Graceffa RF, Gunaydin H, Huang H, La DS, Ligutti J, et al. 1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of Na1.7 inhibition. Bioorganic & Medicinal Chemistry Letters. PMID 29709252 DOI: 10.1016/J.Bmcl.2018.04.035 |
0.306 |
|
| 2017 |
Graceffa RF, Boezio AA, Able J, Altmann S, Berry LM, Boezio CM, Butler JR, Chu-Moyer MY, Cooke M, DiMauro EF, Dineen TA, Feric Bojic E, Foti RS, Fremeau RT, Guzman-Perez A, ... ... Huang H, et al. Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust In Vivo Activity. Journal of Medicinal Chemistry. PMID 28324649 DOI: 10.1021/Acs.Jmedchem.6B01850 |
0.3 |
|
| 2017 |
Weiss MM, Dineen TA, Marx IE, Altmann S, Boezio AA, Bregman H, Chu-Moyer MY, DiMauro EF, Feric Bojic E, Foti RS, Gao H, Graceffa RF, Gunaydin H, Guzman-Perez A, Huang H, et al. Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities. Journal of Medicinal Chemistry. PMID 28287723 DOI: 10.1021/Acs.Jmedchem.6B01851 |
0.307 |
|
| 2016 |
DiMauro EF, Altmann S, Berry LM, Bregman H, Chakka N, Chu-Moyer M, Feric Bojic E, Foti RS, Fremeau RT, Gao H, Gunaydin H, Guzman-Perez A, Hall BE, Huang H, Jarosh M, et al. Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors. Journal of Medicinal Chemistry. PMID 27441383 DOI: 10.1021/Acs.Jmedchem.6B00425 |
0.325 |
|
| 2015 |
Ablikim M, Achasov MN, Ai XC, Albayrak O, Albrecht M, Ambrose DJ, Amoroso A, An FF, An Q, Bai JZ, Ferroli RB, Ban Y, Bennett DW, Bennett JV, Bertani M, ... ... Huang HP, et al. Observation of a Neutral Charmoniumlike State Z_{c}(4025)^{0} in e^{+}e^{-}→(D^{*}D[over ¯]^{*})^{0}π^{0}. Physical Review Letters. 115: 182002. PMID 26565461 DOI: 10.1103/Physrevlett.115.182002 |
0.502 |
|
| 2012 |
Huang H, Acquaviva L, Berry V, Bregman H, Chakka N, O'Connor A, DiMauro EF, Dovey J, Epstein O, Grubinska B, Goldstein J, Gunaydin H, Hua Z, Huang X, Huang L, et al. Structure-Based Design of Potent and Selective CK1γ Inhibitors. Acs Medicinal Chemistry Letters. 3: 1059-64. PMID 24900428 DOI: 10.1021/Ml300278F |
0.307 |
|
| 2012 |
Huang H, La DS, Cheng AC, Whittington DA, Patel VF, Chen K, Dineen TA, Epstein O, Graceffa R, Hickman D, Kiang YH, Louie S, Luo Y, Wahl RC, Wen PH, et al. Structure- and property-based design of aminooxazoline xanthenes as selective, orally efficacious, and CNS penetrable BACE inhibitors for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. 55: 9156-69. PMID 22928914 DOI: 10.1021/Jm300598E |
0.304 |
|
| 2012 |
Dineen TA, Weiss MM, Williamson T, Acton P, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dunn RT, Esmay J, Graceffa RF, Harried SS, ... ... Huang H, et al. Design and synthesis of potent, orally efficacious hydroxyethylamine derived β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 55: 9025-44. PMID 22468684 DOI: 10.1021/Jm300118S |
0.309 |
|
| 2004 |
Huang H, Panek JS. Total synthesis of callipeltoside A Organic Letters. 6: 4383-4385. PMID 15524489 DOI: 10.1021/Ol0480325 |
0.511 |
|
| 2003 |
Huang H, Panek JS. Organosilanes in synthesis: Application to an enantioselective synthesis of methyl-L-callipeltose Organic Letters. 5: 1991-1993. PMID 12762704 DOI: 10.1021/Ol034582B |
0.51 |
|
| 2003 |
Huang H, Spande TF, Panek JS. Highly enantioenriched tetrahydropyridines from chiral organosilanes: Application to the synthesis of quinolizidine alkaloid (-)-217A Journal of the American Chemical Society. 125: 626-627. PMID 12526650 DOI: 10.1021/Ja028937I |
0.51 |
|
| 2001 |
Huang H, Panek JS. Formal [4 + 2]-Annulation of Chiral Crotylsilanes: Synthesis of the C19-C28 Fragment of Phorboxazoles Organic Letters. 3: 1693-1696. PMID 11405688 DOI: 10.1021/Ol015893U |
0.506 |
|
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