Xiaoming Xu, Ph.D. - Publications

Affiliations: 
2008 Chemistry Purdue University, West Lafayette, IN, United States 
Area:
HIV-1 protease inhibitors

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Zhou Y, Xiao Y, Qiu Y, Yuan H, van Blitterswijk CA, Zhou X, Xu X, Bao C. Adhesion and proliferation of cells and bacteria on microchip with different surfaces microstructures. Biomedizinische Technik. Biomedical Engineering. PMID 26684347 DOI: 10.1515/bmt-2015-0075  0.302
2015 Ghosh AK, Brindisi M, Yen YC, Xu X, Huang X, Devasamudram T, Bilcer G, Lei H, Koelsch G, Mesecar AD, Tang J. Structure-based design, synthesis and biological evaluation of novel β-secretase inhibitors containing a pyrazole or thiazole moiety as the P3 ligand. Bioorganic & Medicinal Chemistry Letters. 25: 668-72. PMID 25537272 DOI: 10.1016/J.Bmcl.2014.11.087  0.511
2012 Ghosh AK, Pandey S, Gangarajula S, Kulkarni S, Xu X, Rao KV, Huang X, Tang J. Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5460-5. PMID 22863204 DOI: 10.1016/J.Bmcl.2012.07.043  0.631
2010 Nguyen TL, Xu X, Gussio R, Ghosh AK, Hamel E. The assembly-inducing laulimalide/peloruside a binding site on tubulin: molecular modeling and biochemical studies with [³H]peloruside A. Journal of Chemical Information and Modeling. 50: 2019-28. PMID 21028850 DOI: 10.1021/Ci1002894  0.438
2010 Singh AJ, Xu CX, Xu X, West LM, Wilmes A, Chan A, Hamel E, Miller JH, Northcote PT, Ghosh AK. Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity. The Journal of Organic Chemistry. 75: 2-10. PMID 19957922 DOI: 10.1021/Jo9021265  0.448
2008 Ghosh AK, Kass J, Anderson DD, Xu X, Marian C. L-selectride-mediated highly diastereoselective asymmetric reductive aldol reaction: access to an important subunit for bioactive molecules. Organic Letters. 10: 4811-4. PMID 18831554 DOI: 10.1021/Ol801971T  0.636
2008 Ghosh AK, Xu X, Kim JH, Xu CX. Enantioselective total synthesis of peloruside A: a potent microtubule stabilizer. Organic Letters. 10: 1001-4. PMID 18247632 DOI: 10.1021/Ol703091B  0.422
2008 Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J. Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. Bioorganic & Medicinal Chemistry Letters. 18: 1031-6. PMID 18180160 DOI: 10.1016/J.Bmcl.2007.12.028  0.636
2007 Ghosh AK, Xi K, Grum-Tokars V, Xu X, Ratia K, Fu W, Houser KV, Baker SC, Johnson ME, Mesecar AD. Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 5876-80. PMID 17855091 DOI: 10.1016/J.Bmcl.2007.08.031  0.618
2007 Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni SS, Xu X, Chang W, Weerasena V, Turner R, Koelsch G, Bilcer G, Tang J. Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. Journal of Medicinal Chemistry. 50: 2399-407. PMID 17432843 DOI: 10.1021/Jm061338S  0.643
2005 Ghosh AK, Devasamudram T, Hong L, DeZutter C, Xu X, Weerasena V, Koelsch G, Bilcer G, Tang J. Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase). Bioorganic & Medicinal Chemistry Letters. 15: 15-20. PMID 15582402 DOI: 10.1016/J.Bmcl.2004.10.084  0.434
2004 Ghosh AK, Xu X. Assignment of absolute stereochemistry and total synthesis of (-)-spongidepsin. Organic Letters. 6: 2055-8. PMID 15176817 DOI: 10.1021/ol049292p  0.383
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