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Zhongsheng You, Ph.D. - Publications

Affiliations: 
2002 University of California, San Diego, La Jolla, CA 
Area:
Cell Cycle
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jaiswal RK, Lei KH, Chastain M, Wang Y, Shiva O, Li S, You Z, Chi P, Chai W. CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection. Nature Communications. 14: 7882. PMID 38036565 DOI: 10.1038/s41467-023-43685-2  0.434
2023 Li Y, Wang F, Li X, Wang L, Yang Z, You Z, Peng A. The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery. Elife. 12. PMID 37672026 DOI: 10.7554/eLife.86976  0.576
2023 Li Y, Wang F, Li X, Wang L, Yang Z, You Z, Peng A. The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery. Biorxiv : the Preprint Server For Biology. PMID 36865136 DOI: 10.1101/2023.02.22.529521  0.575
2022 Yang Z, Lemacon DS, Li S, Cheruiyot A, Kong L, Tan K, Cheng C, Turkay E, He D, You Z. Context-dependent pro- and anti-resection roles of ZKSCAN3 in the regulation of fork processing during replication stress. The Journal of Biological Chemistry. 102215. PMID 35779634 DOI: 10.1016/j.jbc.2022.102215  0.309
2021 Cheruiyot A, Li S, Nonavinkere Srivatsan S, Ahmed T, Chen Y, Lemacon DS, Li Y, Yang Z, Wadugu BA, Warner WA, Pruett-Miller SM, Obeng EA, Link DC, He D, Xiao F, ... ... You Z, et al. Nonsense-mediated RNA Decay Is a Unique Vulnerability of Cancer Cells harboring SF3B1 or U2AF1 mutations. Cancer Research. PMID 34215620 DOI: 10.1158/0008-5472.CAN-20-4016  0.315
2020 Zhu C, Rogers A, Asleh K, Won J, Gao D, Leung S, Li S, Vij KR, Zhu J, Held JM, You Z, Nielsen TO, Shao J. Phospho-Ser-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer. Cell Reports. 31: 107745. PMID 32521270 DOI: 10.1016/J.Celrep.2020.107745  0.47
2019 Li S, Lavagnino Z, Lemacon D, Kong L, Ustione A, Ng X, Zhang Y, Wang Y, Zheng B, Piwnica-Worms H, Vindigni A, Piston DW, You Z. Ca-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Molecular Cell. PMID 31053472 DOI: 10.1016/J.Molcel.2019.04.003  0.369
2019 Zhao XT, You ZS, Cheng P, Wang Y. Investigation of Protein-DNA Interactions in Enhancer II and Core Promoter of HBV by in vivo Footprinting. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica Et Biophysica Sinica. 31: 489-493. PMID 12114957  0.368
2018 Lamarche BJ, Orazio NI, Goben B, Meisenhelder J, You Z, Weitzman MD, Hunter T. Repair of protein-linked DNA double strand breaks: Using the adenovirus genome as a model substrate in cell-based assays. Dna Repair. PMID 30583959 DOI: 10.1016/J.Dnarep.2018.12.001  0.429
2018 Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick JAJ, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. Plos One. 13: e0204978. PMID 30289931 DOI: 10.1371/Journal.Pone.0204978  0.366
2018 Nickless A, You Z. Studying Nonsense-Mediated mRNA Decay in Mammalian Cells Using a Multicolored Bioluminescence-Based Reporter System. Methods in Molecular Biology (Clifton, N.J.). 1720: 213-224. PMID 29236262 DOI: 10.1007/978-1-4939-7540-2_16  0.315
2017 Lemaçon D, Jackson J, Quinet A, Brickner JR, Li S, Yazinski S, You Z, Ira G, Zou L, Mosammaparast N, Vindigni A. MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells. Nature Communications. 8: 860. PMID 29038425 DOI: 10.1038/S41467-017-01180-5  0.45
2017 Paudyal SC, Li S, Yan H, Hunter T, You Z. Dna2 initiates resection at clean DNA double-strand breaks. Nucleic Acids Research. PMID 28981724 DOI: 10.1093/Nar/Gkx830  0.597
2017 Nickless A, Cheruiyot A, Flanagan KC, Piwnica-Worms D, Stewart SA, You Z. p38 MAPK Inhibits Nonsense-mediated RNA Decay in Response to Persistent DNA Damage in Non-cycling Cells. The Journal of Biological Chemistry. PMID 28765281 DOI: 10.1074/Jbc.M117.787846  0.592
2017 Nickless A, Bailis JM, You Z. Control of gene expression through the nonsense-mediated RNA decay pathway. Cell & Bioscience. 7: 26. PMID 28533900 DOI: 10.1186/S13578-017-0153-7  0.305
2016 Paudyal SC, You Z. Sharpening the ends for repair: mechanisms and regulation of DNA resection. Acta Biochimica Et Biophysica Sinica. PMID 27174871 DOI: 10.1093/Abbs/Gmw043  0.588
2016 Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z, Zhang Z. USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response. Genes & Development. 30: 946-59. PMID 27083998 DOI: 10.1101/Gad.271841.115  0.595
2016 Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, Deng M, Qin B, Correia C, Lee S, Kim J, Sparks M, Nair AA, Evans DL, Kalari KR, ... ... You Z, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nature Communications. 7: 10201. PMID 26727879 DOI: 10.1038/Ncomms10201  0.574
2015 Cheruiyot A, Paudyal SC, Kim IK, Sparks M, Ellenberger T, Piwnica-Worms H, You Z. Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities. Dna Repair. 35: 106-115. PMID 26519824 DOI: 10.1016/J.Dnarep.2015.09.021  0.596
2015 You Z, Qian H, Wang C, He B, Yan J, Mao C, Wang G. Inhibition of DNA nanotube-conjugated mTOR siRNA on the growth of pulmonary arterial smooth muscle cells. Data in Brief. 5: 28-34. PMID 26380842 DOI: 10.1016/J.Dib.2015.08.002  0.381
2015 You Z, Qian H, Wang C, He B, Yan J, Mao C, Wang G. Regulation of vascular smooth muscle cell autophagy by DNA nanotube-conjugated mTOR siRNA. Biomaterials. 67: 137-150. PMID 26210180 DOI: 10.1016/J.Biomaterials.2015.07.015  0.4
2015 Chen X, Kim IK, Honaker Y, Paudyal SC, Koh WK, Sparks M, Li S, Piwnica-Worms H, Ellenberger T, You Z. 14-3-3 proteins restrain the Exo1 nuclease to prevent overresection. The Journal of Biological Chemistry. 290: 12300-12. PMID 25833945 DOI: 10.1074/Jbc.M115.644005  0.611
2015 Jeffery DC, Kakusho N, You Z, Gharib M, Wyse B, Drury E, Weinreich M, Thibault P, Verreault A, Masai H, Yankulov K. CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin. Cell Cycle (Georgetown, Tex.). 14: 74-85. PMID 25602519 DOI: 10.4161/15384101.2014.973745  0.425
2013 Chen X, Paudyal SC, Chin RI, You Z. PCNA promotes processive DNA end resection by Exo1. Nucleic Acids Research. 41: 9325-38. PMID 23939618 DOI: 10.1093/Nar/Gkt672  0.618
2013 Liu C, Wu J, Paudyal SC, You Z, Yu X. CHFR is important for the first wave of ubiquitination at DNA damage sites. Nucleic Acids Research. 41: 1698-710. PMID 23268447 DOI: 10.1093/Nar/Gks1278  0.579
2012 Daniel JA, Pellegrini M, Lee BS, Guo Z, Filsuf D, Belkina NV, You Z, Paull TT, Sleckman BP, Feigenbaum L, Nussenzweig A. Loss of ATM kinase activity leads to embryonic lethality in mice Journal of Cell Biology. 198: 295-304. PMID 22869595 DOI: 10.1083/Jcb.201204035  0.405
2011 Pei H, Zhang L, Luo K, Qin Y, Chesi M, Fei F, Bergsagel PL, Wang L, You Z, Lou Z. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature. 470: 124-8. PMID 21293379 DOI: 10.1038/Nature09658  0.567
2010 You Z, Bailis JM. DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends in Cell Biology. 20: 402-9. PMID 20444606 DOI: 10.1016/J.Tcb.2010.04.002  0.574
2009 You Z, Shi LZ, Zhu Q, Wu P, Zhang YW, Basilio A, Tonnu N, Verma IM, Berns MW, Hunter T. CtIP links DNA double-strand break sensing to resection. Molecular Cell. 36: 954-69. PMID 20064462 DOI: 10.1016/J.Molcel.2009.12.002  0.615
2009 Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Molecular Cell. 35: 442-53. PMID 19716789 DOI: 10.1016/J.Molcel.2009.06.030  0.487
2007 You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T. Rapid activation of ATM on DNA flanking double-strand breaks. Nature Cell Biology. 9: 1311-8. PMID 17952060 DOI: 10.1038/Ncb1651  0.64
2007 Johnson SA, You Z, Hunter T. Monitoring ATM kinase activity in living cells. Dna Repair. 6: 1277-84. PMID 17428747 DOI: 10.1016/J.Dnarep.2007.02.025  0.578
2006 Petersen P, Chou DM, You Z, Hunter T, Walter JC, Walter G. Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpoint. Molecular and Cellular Biology. 26: 1997-2011. PMID 16479016 DOI: 10.1128/Mcb.26.5.1997-2011.2006  0.689
2005 You Z, Chahwan C, Bailis J, Hunter T, Russell P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Molecular and Cellular Biology. 25: 5363-79. PMID 15964794 DOI: 10.1128/Mcb.25.13.5363-5379.2005  0.52
2002 You Z, Harvey K, Kong L, Newport J. Xic1 degradation in Xenopus egg extracts is coupled to initiation of DNA replication. Genes & Development. 16: 1182-94. PMID 12023298 DOI: 10.1101/Gad.985302  0.682
2002 You Z, Kong L, Newport J. The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint. The Journal of Biological Chemistry. 277: 27088-93. PMID 12015327 DOI: 10.1074/Jbc.M204120200  0.704
2000 Hekmat-Nejad M, You Z, Yee MC, Newport JW, Cimprich KA. Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Current Biology : Cb. 10: 1565-73. PMID 11137007 DOI: 10.1016/S0960-9822(00)00855-1  0.723
1994 Fukushima J, Ishiwata T, Kurata M, You Z, Okuda K. Intracellular receptor-type transcription factor, LasR, contains a highly conserved amphipathic region which precedes the putative helix-turn-helix DNA binding motif. Nucleic Acids Research. 22: 3706-7. PMID 7937080 DOI: 10.1093/nar/22.18.3706  0.32
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