Christopher S. Theile, Ph.D. - Publications

Affiliations: 
2012 Graduate School of Arts & Sciences Boston College, Newton, MA, United States 

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nanna AR, Kel'in AV, Theile C, Pierson JM, Voo ZX, Garg A, Nair JK, Maier MA, Fitzgerald K, Rader C. Generation and validation of structurally defined antibody-siRNA conjugates. Nucleic Acids Research. PMID 32347936 DOI: 10.1093/Nar/Gkaa286  0.306
2018 Parmar RG, Brown CR, Matsuda S, Willoughby JLS, Theile CS, Charissé K, Foster DJ, Zlatev I, Jadhav V, Maier MA, Egli M, Manoharan M, Rajeev KG. Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA Conjugates. Journal of Medicinal Chemistry. PMID 29376650 DOI: 10.1021/Acs.Jmedchem.7B01147  0.406
2018 O'Shea J, Theile CS, Das R, Babu IR, Charisse K, Manoharan M, Maier MA, Zlatev I. An efficient deprotection method for 5′-[O,O-bis(pivaloyloxymethyl)]-(E)-vinylphosphonate containing oligonucleotides Tetrahedron. 74: 6182-6186. DOI: 10.1016/J.Tet.2018.09.008  0.62
2016 Elkayam E, Parmar R, Brown CR, Willoughby JL, Theile CS, Manoharan M, Joshua-Tor L. siRNA carrying an (E)-vinylphosphonate moiety at the 5' end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2. Nucleic Acids Research. PMID 27903888 DOI: 10.1093/Nar/Gkw1171  0.315
2016 Parmar R, Willoughby JL, Liu J, Foster DJ, Brigham B, Theile CS, Charisse K, Akinc A, Guidry E, Pei Y, Strapps W, Cancilla M, Stanton MG, Rajeev KG, Sepp-Lorenzino L, et al. 5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates. Chembiochem : a European Journal of Chemical Biology. PMID 27121751 DOI: 10.1002/Cbic.201600130  0.323
2016 Parmar R, Willoughby JLS, Liu J, Foster DJ, Brigham B, Theile CS, Charisse K, Akinc A, Guidry E, Pei Y, Strapps W, Cancilla M, Stanton MG, Rajeev KG, Sepp-Lorenzino L, et al. Inside Cover: 5′-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates (ChemBioChem 11/2016) Chembiochem. 17: 970-970. DOI: 10.1002/Cbic.201600278  0.322
2014 Shi J, Kundrat L, Pishesha N, Bilate A, Theile C, Maruyama T, Dougan SK, Ploegh HL, Lodish HF. Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes. Proceedings of the National Academy of Sciences of the United States of America. 111: 10131-6. PMID 24982154 DOI: 10.1073/Pnas.1409861111  0.306
2013 Guimaraes CP, Witte MD, Theile CS, Bozkurt G, Kundrat L, Blom AE, Ploegh HL. Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions. Nature Protocols. 8: 1787-99. PMID 23989673 DOI: 10.1038/Nprot.2013.101  0.305
2012 Yueh H, Yu H, Theile CS, Pal A, Horhota A, Greco N, Christianson CV, McLaughlin LW. Synthesis and properties of DNA containing cyclonucleosides Nucleosides, Nucleotides and Nucleic Acids. 31: 661-679. PMID 23004930 DOI: 10.1080/15257770.2012.716189  0.596
2012 Theile CS, McLaughlin LW. An efficient synthetic approach to 6,5′-(S)- and 6,5′-(R)- cyclouridine Chemical Communications. 48: 5587-5589. PMID 22531603 DOI: 10.1039/C2Cc31597A  0.593
2012 Theile CS, McLaughlin LW. Synthesis of 6,6′-(S)-cyclo-2′-deoxyuridine featuring a unique Barbier-style cyclization Rsc Advances. 2: 11678-11680. DOI: 10.1039/C2Ra21559D  0.598
2012 Theile CS, McLaughlin LW. ChemInform Abstract: An Efficient Synthetic Approach to 6,5′-(S)- and 6,5′-(R)-Cyclouridine. Cheminform. 43: no-no. DOI: 10.1002/chin.201239214  0.559
2011 Akabayov B, Kulczyk AW, Akabayov SR, Theile C, McLaughlin LW, Beauchamp B, van Oijen AM, Richardson CC. Pyrovanadolysis, a pyrophosphorolysis-like reaction mediated by pyrovanadate, Mn2+, and DNA polymerase of bacteriophage T7. The Journal of Biological Chemistry. 286: 29146-57. PMID 21697085 DOI: 10.1074/Jbc.M111.250944  0.578
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