| Year |
Citation |
Score |
| 2024 |
Jay KL, Gogate N, Ezell K, Andrews JC, Jangam SV, Hall PI, Pan H, Pham K, German R, Gomez V, Jellinek-Russo E, Storch E, Yamamoto S, Kanca O, Bellen HJ, et al. Resolution of variable expressivity in a multi-generational family using deep clinical phenotyping and models. Medrxiv : the Preprint Server For Health Sciences. PMID 39399018 DOI: 10.1101/2024.09.27.24314092 |
0.6 |
|
| 2024 |
Goodman LD, Ralhan I, Li X, Lu S, Moulton MJ, Park YJ, Zhao P, Kanca O, Ghaderpour Taleghani ZS, Jacquemyn J, Shulman JM, Ando K, Sun K, Ioannou MS, Bellen HJ. Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nature Neuroscience. PMID 39187706 DOI: 10.1038/s41593-024-01740-1 |
0.788 |
|
| 2024 |
Zhao X, Li Y, Zhang S, Sudwarts A, Zhang H, Kozlova A, Moulton MJ, Goodman LD, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J. Alzheimer's disease protective allele of modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication. Medrxiv : the Preprint Server For Health Sciences. PMID 39185522 DOI: 10.1101/2024.08.14.24312009 |
0.794 |
|
| 2024 |
Huang Y, Jay KL, Huang AY, Wan J, Jangam SV, Chorin O, Rothschild A, Barel O, Mariani M, Iascone M, Xue H, Huang J, Mignot C, Keren B, Saillour V, ... ... Bellen HJ, et al. Loss-of-function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 101218. PMID 39036895 DOI: 10.1016/j.gim.2024.101218 |
0.764 |
|
| 2024 |
Mao D, Liu C, Wang L, Ai-Ouran R, Deisseroth C, Pasupuleti S, Kim SY, Li L, Rosenfeld JA, Meng L, Burrage LC, Wangler MF, Yamamoto S, Santana M, Perez V, ... ... Bellen HJ, et al. AI-MARRVEL - A Knowledge-Driven AI System for Diagnosing Mendelian Disorders. Nejm Ai. 1. PMID 38962029 DOI: 10.1056/aioa2300009 |
0.768 |
|
| 2024 |
Moulton MJ, Atala K, Zheng Y, Dutta D, Grange DK, Lin WW, Wegner DJ, Wambach JA, Duker AL, Bober MB, Kratz L, Wise CA, Oxendine I, Khanshour A, Cole FS, ... ... Bellen HJ, et al. Dominant Missense Variants in SREBF2 are Associated with Complex Dermatological, Neurological, and Skeletal Abnormalities. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 101174. PMID 38847193 DOI: 10.1016/j.gim.2024.101174 |
0.801 |
|
| 2024 |
Goodman LD, Moulton MJ, Lin G, Bellen HJ. Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease? Trends in Molecular Medicine. PMID 38755043 DOI: 10.1016/j.molmed.2024.04.010 |
0.772 |
|
| 2024 |
Liao JZ, Chung HL, Shih C, Wong KKL, Dutta D, Nil Z, Burns CG, Kanca O, Park YJ, Zuo Z, Marcogliese PC, Sew K, Bellen HJ, Verheyen EM. Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila. Nature Communications. 15: 3326. PMID 38637532 DOI: 10.1038/s41467-024-47623-8 |
0.802 |
|
| 2024 |
Park YJ, Lu TC, Jackson T, Goodman LD, Ran L, Chen J, Liang CY, Harrison E, Ko C, Hsu AL, Yamamoto S, Qi Y, Bellen HJ, Li H. Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models. Biorxiv : the Preprint Server For Biology. PMID 38559164 DOI: 10.1101/2024.03.10.584317 |
0.716 |
|
| 2024 |
Ma M, Ganapathi M, Zheng Y, Tan KL, Kanca O, Bove KE, Quintanilla N, Sag SO, Temel SG, LeDuc CA, McPartland AJ, Pereira EM, Shen Y, Hagen J, Thomas CP, ... ... Bellen HJ, et al. Homozygous missense variants in YKT6 result in loss of function and are associated with developmental delay, with or without severe infantile liver disease and risk for hepatocellular carcinoma. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 101125. PMID 38522068 DOI: 10.1016/j.gim.2024.101125 |
0.79 |
|
| 2024 |
Pan X, Tao AM, Lu S, Ma M, Hannan SB, Slaugh R, Drewes Williams S, O'Grady L, Kanca O, Person R, Carter MT, Platzer K, Schnabel F, Abou Jamra R, Roberts AE, ... ... Bellen HJ, et al. De novo variants in FRYL are associated with developmental delay, intellectual disability, and dysmorphic features. American Journal of Human Genetics. PMID 38479391 DOI: 10.1016/j.ajhg.2024.02.007 |
0.818 |
|
| 2024 |
Vuocolo B, German RJ, Lalani SR, Murali CN, Bacino CA, Baskin S, Littlejohn R, Odom JD, McLean S, Schmid C, Nutter M, Stuebben M, Magness E, Juarez O, El Achi D, ... ... Bellen H, et al. Improving access to exome sequencing in a medically underserved population through the Texome Project. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 101102. PMID 38431799 DOI: 10.1016/j.gim.2024.101102 |
0.516 |
|
| 2024 |
Martelli F, Lin J, Mele S, Imlach W, Kanca O, Barlow CK, Paril J, Schittenhelm RB, Christodoulou J, Bellen HJ, Piper MDW, Johnson TK. Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics. Cell Reports. 43: 113861. PMID 38416643 DOI: 10.1016/j.celrep.2024.113861 |
0.626 |
|
| 2024 |
Dutta D, Kanca O, Shridharan RV, Marcogliese PC, Steger B, Morimoto M, Frost FG, Macnamara E, Wangler MF, Yamamoto S, Jenny A, Adams D, Malicdan MC, Bellen HJ. Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability. Proceedings of the National Academy of Sciences of the United States of America. 121: e2322582121. PMID 38381787 DOI: 10.1073/pnas.2322582121 |
0.815 |
|
| 2024 |
Goodman LD, Moulton MJ, Bellen HJ. Glial lipid droplets resolve ROS during sleep. Nature Neuroscience. PMID 38360945 DOI: 10.1038/s41593-023-01546-7 |
0.754 |
|
| 2024 |
Ma M, Zheng Y, Lu S, Pan X, Worley KC, Burrage LC, Blieden LS, Allworth A, Chen WL, Merla G, Mandriani B, Rosenfeld JA, Li-Kroeger D, Dutta D, Yamamoto S, ... ... Bellen HJ, et al. variants in are associated with hearing impairment, ocular pathology, and cardiac defects. Medrxiv : the Preprint Server For Health Sciences. PMID 38260438 DOI: 10.1101/2024.01.08.23300523 |
0.81 |
|
| 2023 |
Pan X, Alvarez AN, Ma M, Lu S, Crawford MW, Briere LC, Kanca O, Yamamoto S, Sweetser DA, Wilson JL, Napier RJ, Pruneda JN, Bellen HJ. Allelic strengths of encephalopathy-associated variants correlate between in vivo and in vitro assays. Elife. 12. PMID 38079206 DOI: 10.7554/eLife.89891 |
0.812 |
|
| 2023 |
Nil Z, Deshwar AR, Huang Y, Barish S, Zhang X, Choufani S, Le Quesne Stabej P, Hayes I, Yap P, Haldeman-Englert C, Wilson C, Prescott T, Tveten K, Vøllo A, Haynes D, ... ... Bellen HJ, et al. Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies. American Journal of Human Genetics. PMID 37827158 DOI: 10.1016/j.ajhg.2023.09.009 |
0.786 |
|
| 2023 |
Dutta D, Kanca O, Byeon SK, Marcogliese PC, Zuo Z, Shridharan RV, Park JH, Lin G, Ge M, Heimer G, Kohler JN, Wheeler MT, Kaipparettu BA, Pandey A, Bellen HJ. A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels. Nature Metabolism. PMID 37653044 DOI: 10.1038/s42255-023-00873-0 |
0.787 |
|
| 2023 |
Pan X, Alvarez AN, Ma M, Lu S, Crawford MW, Briere LC, Kanca O, Yamamoto S, Sweetser DA, Wilson JL, Napier RJ, Pruneda JN, Bellen HJ. Allelic strengths of encephalopathy-associated variants correlate between and assays. Medrxiv : the Preprint Server For Health Sciences. PMID 37502976 DOI: 10.1101/2023.07.17.23292782 |
0.81 |
|
| 2023 |
Yamamoto S, Kanca O, Wangler MF, Bellen HJ. Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans. Nature Reviews. Genetics. PMID 37491400 DOI: 10.1038/s41576-023-00633-6 |
0.78 |
|
| 2023 |
Guichard A, Lu S, Kanca O, Bressan D, Huang Y, Ma M, Sanz Juste S, Andrews JC, Jay KL, Sneider M, Schwartz R, Huang MC, Bei D, Pan H, Ma L, ... ... Bellen HJ, et al. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Cell Reports. 42: 112842. PMID 37480566 DOI: 10.1016/j.celrep.2023.112842 |
0.797 |
|
| 2023 |
Ravenscroft TA, Jacobs A, Gu M, Eberl DF, Bellen HJ. The Voltage-Gated Sodium Channel in , Para, Localizes to Dendrites As Well As Axons in Mechanosensitive Chordotonal Neurons. Eneuro. 10. PMID 37328295 DOI: 10.1523/ENEURO.0105-23.2023 |
0.748 |
|
| 2023 |
Lu TC, Brbić M, Park YJ, Jackson T, Chen J, Kolluru SS, Qi Y, Katheder NS, Cai XT, Lee S, Chen YC, Auld N, Liang CY, Ding SH, Welsch D, ... ... Bellen HJ, et al. Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution. Science (New York, N.Y.). 380: eadg0934. PMID 37319212 DOI: 10.1126/science.adg0934 |
0.417 |
|
| 2023 |
Chung HL, Ye Q, Park YJ, Zuo Z, Mok JW, Kanca O, Tattikota SG, Lu S, Perrimon N, Lee HK, Bellen HJ. Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation. Cell Metabolism. PMID 37084732 DOI: 10.1016/j.cmet.2023.03.022 |
0.773 |
|
| 2023 |
Tepe B, Macke EL, Niceta M, Weisz Hubshman M, Kanca O, Schultz-Rogers L, Zarate YA, Schaefer GB, Granadillo De Luque JL, Wegner DJ, Cogne B, Gilbert-Dussardier B, Le Guillou X, Wagner EJ, Pais LS, ... ... Bellen HJ, et al. Bi-allelic variants in INTS11 are associated with a complex neurological disorder. American Journal of Human Genetics. PMID 37054711 DOI: 10.1016/j.ajhg.2023.03.012 |
0.771 |
|
| 2023 |
Ralhan I, Chang J, Moulton MJ, Goodman LD, Lee NYJ, Plummer G, Pasolli HA, Matthies D, Bellen HJ, Ioannou MS. Autolysosomal exocytosis of lipids protect neurons from ferroptosis. The Journal of Cell Biology. 222. PMID 37036445 DOI: 10.1083/jcb.202207130 |
0.79 |
|
| 2023 |
Andrews JC, Mok JW, Kanca O, Jangam S, Tifft C, Macnamara EF, Russell BE, Wang LK, Nelson SF, Bellen HJ, Yamamoto S, Malicdan MCV, Wangler MF. De Novo Variants in MRTFB have gain of function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 100833. PMID 37013900 DOI: 10.1016/j.gim.2023.100833 |
0.795 |
|
| 2023 |
Scott H, Novikov B, Ugur B, Allen B, Mertsalov I, Monagas-Valentin P, Koff M, Baas Robinson S, Aoki K, Veizaj R, Lefeber D, Tiemeyer M, Bellen HJ, Panin V. Glia-neuron coupling via a bipartite sialylation pathway promotes neural transmission and stress tolerance in . Elife. 12. PMID 36946697 DOI: 10.7554/eLife.78280 |
0.721 |
|
| 2023 |
Pan X, Dutta D, Lu S, Bellen HJ. Sphingolipids in neurodegenerative diseases. Frontiers in Neuroscience. 17: 1137893. PMID 36875645 DOI: 10.3389/fnins.2023.1137893 |
0.792 |
|
| 2022 |
Mele S, Martelli F, Lin J, Kanca O, Christodoulou J, Bellen HJ, Piper MDW, Johnson TK. Drosophila as a diet discovery tool for treating amino acid disorders. Trends in Endocrinology and Metabolism: Tem. PMID 36567227 DOI: 10.1016/j.tem.2022.12.004 |
0.63 |
|
| 2022 |
Sinha Ray S, Dutta D, Dennys C, Powers S, Roussel F, Lisowski P, Glažar P, Zhang X, Biswas P, Caporale JR, Rajewsky N, Bickle M, Wein N, Bellen HJ, Likhite S, et al. Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy. Cell Reports. 41: 111751. PMID 36476864 DOI: 10.1016/j.celrep.2022.111751 |
0.807 |
|
| 2022 |
Bosch JA, Ugur B, Pichardo-Casas I, Rabasco J, Escobedo F, Zuo Z, Brown B, Celniker S, Sinclair DA, Bellen HJ, Perrimon N. Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in . Elife. 11. PMID 36346220 DOI: 10.7554/eLife.82709 |
0.744 |
|
| 2022 |
Huang Y, Lemire G, Briere LC, Liu F, Wessels MW, Wang X, Osmond M, Kanca O, Lu S, High FA, Walker MA, Rodan LH, Wangler MF, Yamamoto S, Kernohan KD, ... ... Bellen HJ, et al. The recurrent de novo c.2011C>T missense variant in MTSS2 causes syndromic intellectual disability. American Journal of Human Genetics. 109: 2092. PMID 36332614 DOI: 10.1016/j.ajhg.2022.10.001 |
0.766 |
|
| 2022 |
Ma M, Zhang X, Zheng Y, Lu S, Pan X, Mao X, Pan H, Chung HL, Wang H, Guo H, Bellen HJ. The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival. Human Molecular Genetics. PMID 36255738 DOI: 10.1093/hmg/ddac259 |
0.822 |
|
| 2022 |
Lu S, Ma M, Mao X, Bacino CA, Jankovic J, Sutton VR, Bartley JA, Wang X, Rosenfeld JA, Beleza-Meireles A, Chauhan J, Pan X, Li M, Liu P, Prescott K, ... ... Bellen HJ, et al. De novo variants in FRMD5 are associated with developmental delay, intellectual disability, ataxia, and abnormalities of eye movement. American Journal of Human Genetics. 109: 1932-1943. PMID 36206744 DOI: 10.1016/j.ajhg.2022.09.005 |
0.801 |
|
| 2022 |
Huang Y, Lemire G, Briere LC, Liu F, Wessels MW, Wang X, Osmond M, Kanca O, Lu S, High FA, Walker MA, Rodan LH, Kernohan KD, Sweetser DA, Boycott KM, ... Bellen HJ, et al. The recurrent de novo c.2011C>T missense variant in MTSS2 causes syndromic intellectual disability. American Journal of Human Genetics. PMID 36067766 DOI: 10.1016/j.ajhg.2022.08.011 |
0.808 |
|
| 2022 |
Thomas AX, Link N, Robak LA, Demmler-Harrison G, Pao EC, Squire AE, Michels S, Cohen JS, Comi A, Prontera P, Verrotti di Pianella A, Di Cara G, Garavelli L, Caraffi SG, Fusco C, ... ... Bellen HJ, et al. ANKLE2-related microcephaly: A variable microcephaly syndrome resembling Zika infection. Annals of Clinical and Translational Neurology. PMID 35871307 DOI: 10.1002/acn3.51629 |
0.746 |
|
| 2022 |
Wang L, Lin G, Zuo Z, Li Y, Byeon SK, Pandey A, Bellen HJ. Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia. Science Advances. 8: eabn3326. PMID 35857503 DOI: 10.1126/sciadv.abn3326 |
0.365 |
|
| 2022 |
Kanca O, Zirin J, Hu Y, Tepe B, Dutta D, Lin WW, Ma L, Ge M, Zuo Z, Liu LP, Levis RW, Perrimon N, Bellen HJ. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination. Elife. 11. PMID 35723254 DOI: 10.7554/eLife.76077 |
0.79 |
|
| 2022 |
Wang Y, Lobb-Rabe M, Ashley J, Chatterjee P, Anand V, Bellen HJ, Kanca O, Carrillo RA. Systematic expression profiling of dprs and DIPs reveals cell surface codes in Drosophila larval motor and sensory neurons. Development (Cambridge, England). PMID 35502740 DOI: 10.1242/dev.200355 |
0.67 |
|
| 2022 |
Ma M, Moulton MJ, Lu S, Bellen HJ. 'Fly-ing' from rare to common neurodegenerative disease mechanisms. Trends in Genetics : Tig. PMID 35484057 DOI: 10.1016/j.tig.2022.03.018 |
0.789 |
|
| 2022 |
Barish S, Senturk M, Schoch K, Minogue AL, Lopergolo D, Fallerini C, Harland J, Seemann JH, Stong N, Kranz PG, Kansagra S, Mikati MA, Jasien J, El-Dairi M, Galluzzi P, ... ... Bellen HJ, et al. The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder. Human Molecular Genetics. PMID 35405010 DOI: 10.1093/hmg/ddac085 |
0.795 |
|
| 2022 |
Huang Y, Ma M, Mao X, Pehlivan D, Kanca O, Un-Candan F, Shu L, Akay G, Mitani T, Lu S, Candan S, Wang H, Xiao B, Lupski JR, Bellen HJ. Novel dominant and recessive variants in human ROBO1 cause distinct neurodevelopmental defects through different mechanisms. Human Molecular Genetics. PMID 35348658 DOI: 10.1093/hmg/ddac070 |
0.818 |
|
| 2022 |
Lu S, Hernan R, Marcogliese PC, Huang Y, Gertler TS, Akcaboy M, Liu S, Chung HL, Pan X, Sun X, Oguz MM, Oztoprak U, de Baaij JHF, Ivanisevic J, McGinnis E, ... ... Bellen HJ, et al. Loss-of-function variants in TIAM1 are associated with developmental delay, intellectual disability, and seizures. American Journal of Human Genetics. PMID 35240055 DOI: 10.1016/j.ajhg.2022.01.020 |
0.812 |
|
| 2022 |
Chung HL, Rump P, Lu D, Glassford MR, Mok JW, Fatih J, Basal A, Marcogliese PC, Kanca O, Rapp M, Fock JM, Kamsteeg EJ, Lupski JR, Larson A, Haninbal MC, ... Bellen H, et al. De novo variants in EMC1 lead to neurodevelopmental delay and cerebellar degeneration and affect glial function in drosophila. Human Molecular Genetics. PMID 35234901 DOI: 10.1093/hmg/ddac053 |
0.8 |
|
| 2022 |
Harnish JM, Li L, Rogic S, Poirier-Morency G, Kim SY, Network UD, Boycott KM, Wangler MF, Bellen HJ, Hieter P, Pavlidis P, Liu Z, Yamamoto S. ModelMatcher: A scientist-centric online platform to facilitate collaborations between stakeholders of rare and undiagnosed disease research. Human Mutation. PMID 35224820 DOI: 10.1002/humu.24364 |
0.789 |
|
| 2022 |
Accogli A, Lu S, Musante I, Scudieri P, Rosenfeld JA, Severino M, Baldassari S, Iacomino M, Riva A, Balagura G, Piccolo G, Minetti C, Roberto D, Xia F, Razak R, ... ... Bellen HJ, et al. Loss of Neuron Navigator 2 Impairs Brain and Cerebellar Development. Cerebellum (London, England). PMID 35218524 DOI: 10.1007/s12311-022-01379-3 |
0.824 |
|
| 2022 |
Martelli F, Hernandes NH, Zuo Z, Wang J, Wong CO, Karagas NE, Roessner U, Rupasinghe T, Robin C, Venkatachalam K, Perry T, Batterham P, Bellen HJ. Low doses of the organic insecticide spinosad trigger lysosomal defects, elevated ROS, lipid dysregulation, and neurodegeneration in flies. Elife. 11. PMID 35191376 DOI: 10.7554/eLife.73812 |
0.524 |
|
| 2022 |
Marcogliese PC, Dutta D, Ray SS, Dang NDP, Zuo Z, Wang Y, Lu D, Fazal F, Ravenscroft TA, Chung H, Kanca O, Wan J, Douine ED, Network UD, Pena LDM, ... ... Bellen HJ, et al. Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Science Advances. 8: eabl5613. PMID 35044823 DOI: 10.1126/sciadv.abl5613 |
0.807 |
|
| 2021 |
Moulton MJ, Barish S, Ralhan I, Chang J, Goodman LD, Harland JG, Marcogliese PC, Johansson JO, Ioannou MS, Bellen HJ. Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34949639 DOI: 10.1073/pnas.2112095118 |
0.794 |
|
| 2021 |
Manivannan SN, Roovers J, Smal N, Myers CT, Turkdogan D, Roelens F, Kanca O, Chung HL, Scholz T, Hermann K, Bierhals T, Caglayan HS, Stamberger H, Mefford H, ... ... Bellen HJ, et al. De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies. Brain : a Journal of Neurology. PMID 34788397 DOI: 10.1093/brain/awab409 |
0.813 |
|
| 2021 |
Goodman LD, Bellen HJ. Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila. Current Opinion in Neurobiology. 72: 32-38. PMID 34418791 DOI: 10.1016/j.conb.2021.07.012 |
0.666 |
|
| 2021 |
Park YJ, Kim S, Shim HP, Park JH, Lee G, Kim TY, Jo MC, Kwon AY, Lee M, Lee S, Yeo J, Chung HL, Bellen HJ, Kwon SH, Jeon SH. Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function. Iscience. 24: 102899. PMID 34401677 DOI: 10.1016/j.isci.2021.102899 |
0.762 |
|
| 2021 |
Goodman LD, Cope H, Nil Z, Ravenscroft TA, Charng WL, Lu S, Tien AC, Pfundt R, Koolen DA, Haaxma CA, Veenstra-Knol HE, Wassink-Ruiter JSK, Wevers MR, Jones M, Walsh LE, ... ... Bellen HJ, et al. TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila. American Journal of Human Genetics. PMID 34314705 DOI: 10.1016/j.ajhg.2021.06.019 |
0.815 |
|
| 2021 |
Ravenscroft TA, Phillips JB, Fieg E, Bajikar SS, Peirce J, Wegner J, Luna AA, Fox EJ, Yan YL, Rosenfeld JA, Zirin J, Kanca O, Benke PJ, Cameron ES, ... ... Bellen HJ, et al. Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34113007 DOI: 10.1038/s41436-021-01216-8 |
0.808 |
|
| 2021 |
Baldridge D, Wangler MF, Bowman AN, Yamamoto S, Schedl T, Pak SC, Postlethwait JH, Shin J, Solnica-Krezel L, Bellen HJ, Westerfield M. Model organisms contribute to diagnosis and discovery in the undiagnosed diseases network: current state and a future vision. Orphanet Journal of Rare Diseases. 16: 206. PMID 33962631 DOI: 10.1186/s13023-021-01839-9 |
0.636 |
|
| 2021 |
Luo X, Schoch K, Jangam SV, Bhavana VH, Graves HK, Kansagra S, Jasien J, Stong N, Keren B, Mignot C, Ravelli C, Bellen HJ, Wangler MF, Shashi V, et al. Rare deleterious de novo missense variants in RNF2/RING2 are associated with a neurodevelopmental disorder with unique clinical features. Human Molecular Genetics. PMID 33864376 DOI: 10.1093/hmg/ddab110 |
0.658 |
|
| 2020 |
Cunningham KM, Maulding K, Ruan K, Senturk M, Grima JC, Sung H, Zuo Z, Song H, Gao J, Dubey S, Rothstein JD, Zhang K, Bellen HJ, Lloyd TE. TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS. Elife. 9. PMID 33300868 DOI: 10.7554/eLife.59419 |
0.515 |
|
| 2020 |
Barish S, Barakat TS, Michel BC, Mashtalir N, Phillips JB, Valencia AM, Ugur B, Wegner J, Scott TM, Bostwick B, Murdock DR, Dai H, Perenthaler E, Nikoncuk A, ... ... Bellen HJ, et al. BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. American Journal of Human Genetics. PMID 33232675 DOI: 10.1016/j.ajhg.2020.11.003 |
0.812 |
|
| 2020 |
Martelli F, Zhongyuan Z, Wang J, Wong CO, Karagas NE, Roessner U, Rupasinghe T, Venkatachalam K, Perry T, Bellen HJ, Batterham P. Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments in . Proceedings of the National Academy of Sciences of the United States of America. PMID 32989137 DOI: 10.1073/pnas.2011828117 |
0.547 |
|
| 2020 |
Link N, Bellen HJ. Using to drive the diagnosis and understand the mechanisms of rare human diseases. Development (Cambridge, England). 147. PMID 32988995 DOI: 10.1242/dev.191411 |
0.759 |
|
| 2020 |
Ravenscroft TA, Janssens J, Lee PT, Tepe B, Marcogliese PC, Makhzami S, Holmes TC, Aerts S, Bellen HJ. voltage-gated sodium channels are only expressed in active neurons and are localized to distal axonal initial segment-like domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32928889 DOI: 10.1523/Jneurosci.0142-20.2020 |
0.787 |
|
| 2020 |
Ding X, Jo J, Wang CY, Cristobal CD, Zuo Z, Ye Q, Wirianto M, Lindeke-Myers A, Choi JM, Mohila CA, Kawabe H, Jung SY, Bellen HJ, Yoo SH, Lee HK. The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation. Genes & Development. PMID 32792353 DOI: 10.1101/Gad.338046.120 |
0.343 |
|
| 2020 |
Kao CY, Xu M, Wang L, Lin SC, Lee HJ, Duraine L, Bellen HJ, Goldstein DS, Tsai SY, Tsai MJ. Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson's disease through mitochondrial dysfunction. Plos Genetics. 16: e1008868. PMID 32579581 DOI: 10.1371/journal.pgen.1008868 |
0.317 |
|
| 2020 |
Dutta D, Briere LC, Kanca O, Marcogliese PC, Walker MA, High FA, Vanderver A, Krier J, Carmichael N, Callahan C, Taft RJ, Simons C, Helman G, Network UD, Wangler MF, ... ... Bellen HJ, et al. De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment. Human Molecular Genetics. PMID 32356556 DOI: 10.1093/Hmg/Ddaa081 |
0.81 |
|
| 2020 |
Huang Y, Mao X, van Jaarsveld RH, Shu L, Terhal PA, Jia Z, Xi H, Peng Y, Yan H, Yuan S, Li Q, Wang H, Bellen HJ. Variants in CAPZA2, a member of a F-actin capping complex, cause intellectual disability and developmental delay. Human Molecular Genetics. PMID 32338762 DOI: 10.1093/hmg/ddaa078 |
0.356 |
|
| 2020 |
Chung HL, Mao X, Wang H, Park YJ, Marcogliese PC, Rosenfeld JA, Burrage LC, Liu P, Murdock DR, Yamamoto S, Wangler MF, Chao HT, Long H, Feng L, ... ... Bellen HJ, et al. De Novo Variants in CDK19 Are Associated with a Syndrome Involving Intellectual Disability and Epileptic Encephalopathy. American Journal of Human Genetics. PMID 32330417 DOI: 10.1016/J.Ajhg.2020.04.001 |
0.815 |
|
| 2020 |
Ye H, Ojelade SA, Li-Kroeger D, Zuo Z, Wang L, Li Y, Gu JYJ, Tepass U, Rodal AA, Bellen HJ, Shulman JM. Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 9. PMID 32286230 DOI: 10.7554/Elife.51977 |
0.809 |
|
| 2020 |
Mao D, Reuter CM, Ruzhnikov MRZ, Beck AE, Farrow EG, Emrick LT, Rosenfeld JA, Mackenzie KM, Robak L, Wheeler MT, Burrage LC, Jain M, Liu P, Calame D, Küry S, ... ... Bellen HJ, et al. De novo EIF2AK1 and EIF2AK2 Variants Are Associated with Developmental Delay, Leukoencephalopathy, and Neurologic Decompensation. American Journal of Human Genetics. PMID 32197074 DOI: 10.1016/J.Ajhg.2020.02.016 |
0.811 |
|
| 2020 |
Chung HL, Wangler MF, Marcogliese PC, Jo J, Ravenscroft TA, Zuo Z, Duraine L, Sadeghzadeh S, Li-Kroeger D, Schmidt RE, Pestronk A, Rosenfeld JA, Burrage L, Herndon MJ, Chen S, ... ... Bellen HJ, et al. Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms. Neuron. PMID 32169171 DOI: 10.1016/J.Neuron.2020.02.021 |
0.806 |
|
| 2020 |
Bosch JA, Knight S, Kanca O, Zirin J, Yang-Zhou D, Hu Y, Rodiger J, Amador G, Bellen HJ, Perrimon N, Mohr SE. Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. Current Protocols in Molecular Biology. 130: e112. PMID 31869524 DOI: 10.1002/cpmb.112 |
0.69 |
|
| 2020 |
Ye H, Ojelade SA, Li-Kroeger D, Zuo Z, Wang L, Li Y, Gu JY, Tepass U, Rodal AA, Bellen HJ, Shulman JM. Author response: Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain Elife. DOI: 10.7554/Elife.51977.Sa2 |
0.784 |
|
| 2019 |
Wang J, Rousseau J, Kim E, Ehresmann S, Cheng YT, Duraine L, Zuo Z, Park YJ, Li-Kroeger D, Bi W, Wong LJ, Rosenfeld J, Gleeson J, Faqeih E, Alkuraya FS, ... ... Bellen HJ, et al. Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction. American Journal of Human Genetics. PMID 31785787 DOI: 10.1016/J.Ajhg.2019.11.002 |
0.818 |
|
| 2019 |
Link N, Chung H, Jolly A, Withers M, Tepe B, Arenkiel BR, Shah PS, Krogan NJ, Aydin H, Geckinli BB, Tos T, Isikay S, Tuysuz B, Mochida GH, Thomas AX, ... ... Bellen HJ, et al. Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. Developmental Cell. PMID 31735666 DOI: 10.1016/J.Devcel.2019.10.009 |
0.818 |
|
| 2019 |
Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Bellen HJ, et al. An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Elife. 8. PMID 31674908 DOI: 10.7554/Elife.51539 |
0.774 |
|
| 2019 |
Kanca O, Bellen HJ. La CaSSA da Drosophila: A Versatile Expansion of the Tool Box. Neuron. 104: 177-179. PMID 31647888 DOI: 10.1016/J.Neuron.2019.10.004 |
0.655 |
|
| 2019 |
Guo H, Bettella E, Marcogliese PC, Zhao R, Andrews JC, Nowakowski TJ, Gillentine MA, Hoekzema K, Wang T, Wu H, Jangam S, Liu C, Ni H, Willemsen MH, van Bon BW, ... ... Bellen HJ, et al. Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. Nature Communications. 10: 4679. PMID 31616000 DOI: 10.1038/S41467-019-12435-8 |
0.812 |
|
| 2019 |
Ansar M, Chung HL, Al-Otaibi A, Elagabani MN, Ravenscroft TA, Paracha SA, Scholz R, Abdel Magid T, Sarwar MT, Shah SF, Qaisar AA, Makrythanasis P, Marcogliese PC, Kamsteeg EJ, Falconnet E, ... ... Bellen HJ, et al. Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature. American Journal of Human Genetics. PMID 31607425 DOI: 10.1016/J.Ajhg.2019.09.013 |
0.814 |
|
| 2019 |
Wang J, Mao D, Fazal F, Kim SY, Yamamoto S, Bellen H, Liu Z. Using MARRVEL v1.2 for Bioinformatics Analysis of Human Genes and Variant Pathogenicity. Current Protocols in Bioinformatics. 67: e85. PMID 31524990 DOI: 10.1002/Cpbi.85 |
0.784 |
|
| 2019 |
Kanca O, Andrews JC, Lee PT, Patel C, Braddock SR, Slavotinek AM, Cohen JS, Gubbels CS, Aldinger KA, Williams J, Indaram M, Fatemi A, Yu TW, Agrawal PB, Vezina G, ... ... Bellen HJ, et al. De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. American Journal of Human Genetics. 105: 672-674. PMID 31491411 DOI: 10.1016/J.Ajhg.2019.07.017 |
0.776 |
|
| 2019 |
Wang J, Liu Z, Bellen HJ, Yamamoto S. Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information. Journal of Visualized Experiments : Jove. PMID 31475990 DOI: 10.3791/59542 |
0.672 |
|
| 2019 |
Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Reports. 28: 1799-1813.e5. PMID 31412248 DOI: 10.1016/J.Celrep.2019.07.041 |
0.813 |
|
| 2019 |
Kanca O, Andrews JC, Lee PT, Patel C, Braddock SR, Slavotinek AM, Cohen JS, Gubbels CS, Aldinger KA, Williams J, Indaram M, Fatemi A, Yu TW, Agrawal PB, Vezina G, ... ... Bellen HJ, et al. De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. American Journal of Human Genetics. PMID 31327508 DOI: 10.1016/J.Ajhg.2019.06.014 |
0.816 |
|
| 2019 |
Bellen HJ, Wangler MF, Yamamoto S. The fruit fly at the interface of diagnosis and pathogenic mechanisms of rare and common human diseases. Human Molecular Genetics. PMID 31227826 DOI: 10.1093/Hmg/Ddz135 |
0.67 |
|
| 2019 |
Şentürk M, Mao D, Bellen HJ. Loss of proteins associated with amyotrophic lateral sclerosis affect lysosomal acidification via different routes. Autophagy. 1-3. PMID 31032688 DOI: 10.1080/15548627.2019.1609863 |
0.809 |
|
| 2019 |
Şentürk M, Lin G, Zuo Z, Mao D, Watson E, Mikos AG, Bellen HJ. Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification. Nature Cell Biology. PMID 30804504 DOI: 10.1038/S41556-019-0281-X |
0.809 |
|
| 2019 |
Mao D, Lin G, Tepe B, Zuo Z, Tan KL, Senturk M, Zhang S, Arenkiel BR, Sardiello M, Bellen HJ. VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway. Autophagy. PMID 30741620 DOI: 10.1080/15548627.2019.1580103 |
0.811 |
|
| 2019 |
Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin W, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Bellen HJ, et al. Author response: An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms Elife. DOI: 10.7554/Elife.51539.024 |
0.715 |
|
| 2018 |
Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, ... ... Bellen HJ, et al. Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. Cell. 175: 1931-1945.e18. PMID 30550790 DOI: 10.1016/J.Cell.2018.11.028 |
0.741 |
|
| 2018 |
Lin G, Wang L, Marcogliese PC, Bellen HJ. Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism. Trends in Endocrinology and Metabolism: Tem. PMID 30528460 DOI: 10.1016/J.Tem.2018.11.003 |
0.739 |
|
| 2018 |
Cosmanescu F, Katsamba PS, Sergeeva AP, Ahlsen G, Patel SD, Brewer JJ, Tan L, Xu S, Xiao Q, Nagarkar-Jaiswal S, Nern A, Bellen HJ, Zipursky SL, Honig B, Shapiro L. Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. PMID 30467080 DOI: 10.1016/J.Neuron.2018.10.046 |
0.8 |
|
| 2018 |
Xu S, Xiao Q, Cosmanescu F, Sergeeva AP, Yoo J, Lin Y, Katsamba PS, Ahlsen G, Kaufman J, Linaval NT, Lee PT, Bellen HJ, Shapiro L, Honig B, Tan L, et al. Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits. Neuron. PMID 30467079 DOI: 10.1016/J.Neuron.2018.11.001 |
0.598 |
|
| 2018 |
Splinter K, Adams DR, Bacino CA, Bellen HJ, Bernstein JA, Cheatle-Jarvela AM, Eng CM, Esteves C, Gahl WA, Hamid R, Jacob HJ, Kikani B, Koeller DM, Kohane IS, Lee BH, et al. Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease. The New England Journal of Medicine. PMID 30304647 DOI: 10.1056/Nejmoa1714458 |
0.631 |
|
| 2018 |
Ansar M, Chung HL, Taylor RL, Nazir A, Imtiaz S, Sarwar MT, Manousopoulou A, Makrythanasis P, Saeed S, Falconnet E, Guipponi M, Pournaras CJ, Ansari MA, Ranza E, Santoni FA, ... ... Bellen HJ, et al. Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts. American Journal of Human Genetics. 103: 568-578. PMID 30290152 DOI: 10.1016/j.ajhg.2018.09.004 |
0.758 |
|
| 2018 |
Marcogliese PC, Shashi V, Spillmann RC, Stong N, Rosenfeld JA, Koenig MK, Martínez-Agosto JA, Herzog M, Chen AH, Dickson PI, Lin HJ, Vera MU, Salamon N, Graham JM, Ortiz D, ... ... Bellen HJ, et al. IRF2BPL Is Associated with Neurological Phenotypes. American Journal of Human Genetics. 103: 456. PMID 30193138 DOI: 10.1016/j.ajhg.2018.08.010 |
0.781 |
|
| 2018 |
Li-Kroeger D, Kanca O, Lee PT, Cowan S, Lee MT, Jaiswal M, Salazar JL, He Y, Zuo Z, Bellen HJ. An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in . Elife. 7. PMID 30091705 DOI: 10.7554/Elife.38709 |
0.798 |
|
| 2018 |
Marcogliese PC, Shashi V, Spillmann RC, Stong N, Rosenfeld JA, Koenig MK, Martínez-Agosto JA, Herzog M, Chen AH, Dickson PI, Lin HJ, Vera MU, Salamon N, Ortiz D, Infante E, ... ... Bellen HJ, et al. IRF2BPL Is Associated with Neurological Phenotypes. American Journal of Human Genetics. PMID 30057031 DOI: 10.1016/J.Ajhg.2018.07.006 |
0.826 |
|
| 2018 |
Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, ... ... Bellen HJ, et al. The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. Cell. 174: 505-520. PMID 30053424 DOI: 10.1016/J.Cell.2018.06.016 |
0.315 |
|
| 2018 |
Lin G, Lee PT, Chen K, Mao D, Tan KL, Zuo Z, Lin WW, Wang L, Bellen HJ. Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain. Cell Metabolism. PMID 29909971 DOI: 10.1016/J.Cmet.2018.05.019 |
0.818 |
|
| 2018 |
Li T, Bellen HJ, Groves AK. Using to study mechanisms of hereditary hearing loss. Disease Models & Mechanisms. 11. PMID 29853544 DOI: 10.1242/Dmm.031492 |
0.738 |
|
| 2018 |
Ansar M, Chung H, Waryah YM, Makrythanasis P, Falconnet E, Rao AR, Guipponi M, Narsani AK, Fingerhut R, Santoni FA, Ranza E, Waryah AM, Bellen HJ, Antonarakis SE. Visual impairment and progressive phthisis bulbi caused by recessive pathogenic variant in MARK3. Human Molecular Genetics. PMID 29771303 DOI: 10.1093/hmg/ddy180 |
0.75 |
|
| 2018 |
Liu N, Schoch K, Luo X, Pena L, Bhavana VH, Kukolich MK, Stringer S, Powis Z, Radtke K, Mroske C, Deak K, McDonald MT, McConkie-Rosell A, Markert ML, Kranz PG, ... ... Bellen HJ, et al. Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. Human Molecular Genetics. PMID 29726930 DOI: 10.1093/Hmg/Ddy146 |
0.688 |
|
| 2018 |
Tan KL, Haelterman NA, Kwartler CS, Regalado ES, Lee PT, Nagarkar-Jaiswal S, Guo DC, Duraine L, Wangler MF, Bamshad MJ, Nickerson DA, Lin G, Milewicz DM, Bellen HJ. Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. Developmental Cell. 45: 226-244.e8. PMID 29689197 DOI: 10.1016/J.Devcel.2018.03.020 |
0.801 |
|
| 2018 |
Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Bellen HJ, et al. A gene-specificlibrary for. Elife. 7. PMID 29565247 DOI: 10.7554/Elife.35574 |
0.806 |
|
| 2018 |
Wangler MF, Assia Batzir N, Robak LA, Koenig MK, Bacino CA, Scaglia F, Bellen HJ. The expanding neurological phenotype of DNM1L-related disorders. Brain : a Journal of Neurology. PMID 29529134 DOI: 10.1093/brain/awy024 |
0.565 |
|
| 2018 |
Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Correction: Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 16: e1002622. PMID 29509758 DOI: 10.1371/Journal.Pbio.1002622 |
0.769 |
|
| 2018 |
Oláhová M, Yoon WH, Thompson K, Jangam S, Fernandez L, Davidson JM, Kyle JE, Grove ME, Fisk DG, Kohler JN, Holmes M, Dries AM, Huang Y, Zhao C, Contrepois K, ... ... Bellen HJ, et al. Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder. American Journal of Human Genetics. PMID 29478781 DOI: 10.1016/J.Ajhg.2018.01.020 |
0.652 |
|
| 2018 |
Li-Kroeger D, Kanca O, Lee P, Cowan S, Lee MT, Jaiswal M, Salazar JL, He Y, Zuo Z, Bellen HJ. Author response: An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila Elife. DOI: 10.7554/Elife.38709.023 |
0.779 |
|
| 2018 |
Lee P, Zirin J, Kanca O, Lin W, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Bellen HJ, et al. Author response: A gene-specific T2A-GAL4 library for Drosophila Elife. DOI: 10.7554/Elife.35574.023 |
0.781 |
|
| 2017 |
Ugur B, Bao H, Stawarski M, Duraine LR, Zuo Z, Lin YQ, Neely GG, Macleod GT, Chapman ER, Bellen HJ. The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. Cell Reports. 21: 3794-3806. PMID 29281828 DOI: 10.1016/J.Celrep.2017.12.005 |
0.729 |
|
| 2017 |
Landrock KK, Sullivan P, Martini-Stoica H, Goldstein DS, Graham BH, Yamamoto S, Bellen HJ, Gibbs RA, Chen R, D'Amelio M, Stoica G. Pleiotropic Neuropathological and Biochemical Alterations Associated with Myo5a Mutation in a Rat Model. Brain Research. PMID 29217155 DOI: 10.1016/J.Brainres.2017.11.029 |
0.51 |
|
| 2017 |
Kanca O, Bellen H, Schnorrer F. Gene tagging strategies to assess protein expression, localization and function in Drosophila (vol 207, pg 389, 2017) Genetics. 207: 1711. PMID 29203702 DOI: 10.1534/Genetics.117.300392 |
0.687 |
|
| 2017 |
Şentürk M, Bellen HJ. Genetic strategies to tackle neurological diseases in fruit flies. Current Opinion in Neurobiology. 50: 24-32. PMID 29128849 DOI: 10.1016/j.conb.2017.10.017 |
0.335 |
|
| 2017 |
Kanca O, Bellen HJ, Schnorrer F. Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. Genetics. 207: 389-412. PMID 28978772 DOI: 10.1534/Genetics.117.199968 |
0.69 |
|
| 2017 |
Liu L, MacKenzie KR, Putluri N, Maletić-Savatić M, Bellen HJ. The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metabolism. PMID 28965825 DOI: 10.1016/J.Cmet.2017.08.024 |
0.623 |
|
| 2017 |
Wangler MF, Yamamoto S, Chao HT, Posey JE, Westerfield M, Postlethwait J, Hieter P, Boycott KM, Campeau PM, Bellen HJ. Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research. Genetics. 207: 9-27. PMID 28874452 DOI: 10.1534/Genetics.117.203067 |
0.722 |
|
| 2017 |
Luo X, Rosenfeld JA, Yamamoto S, Harel T, Zuo Z, Hall M, Wierenga K, Pastore MT, Bartholomew D, Delgado MR, Rotenberg J, Lewis RA, Emrick L, Bacino CA, Eldomery MK, ... ... Bellen HJ, et al. Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially. Plos Genetics. 13: e1006905. PMID 28742085 DOI: 10.1371/Journal.Pgen.1006905 |
0.705 |
|
| 2017 |
Wangler MF, Chao YH, Bayat V, Giagtzoglou N, Shinde AB, Putluri N, Coarfa C, Donti T, Graham BH, Faust JE, McNew JA, Moser A, Sardiello M, Baes M, Bellen HJ. Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse. Plos Genetics. 13: e1006825. PMID 28640802 DOI: 10.1371/Journal.Pgen.1006825 |
0.801 |
|
| 2017 |
Chao HT, Liu L, Bellen HJ. Building dialogues between clinical and biomedical research through cross-species collaborations. Seminars in Cell & Developmental Biology. PMID 28579453 DOI: 10.1016/J.Semcdb.2017.05.022 |
0.668 |
|
| 2017 |
Wong CO, Gregory S, Hu H, Chao Y, Sepúlveda VE, He Y, Li-Kroeger D, Goldman WE, Bellen HJ, Venkatachalam K. Lysosomal Degradation Is Required for Sustained Phagocytosis of Bacteria by Macrophages. Cell Host & Microbe. PMID 28579255 DOI: 10.1016/J.Chom.2017.05.002 |
0.735 |
|
| 2017 |
Nagarkar-Jaiswal S, Manivannan SN, Zuo Z, Bellen HJ. A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells. Elife. 6. PMID 28561736 DOI: 10.7554/Elife.26420 |
0.802 |
|
| 2017 |
Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ. MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. American Journal of Human Genetics. PMID 28502612 DOI: 10.1016/J.Ajhg.2017.04.010 |
0.794 |
|
| 2017 |
Malmanche N, Dourlen P, Gistelinck M, Demiautte F, Link N, Dupont C, Vanden Broeck L, Werkmeister E, Amouyel P, Bongiovanni A, Bauderlique H, Moechars D, Royou A, Bellen HJ, Lafont F, et al. Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models. Scientific Reports. 7: 40764. PMID 28112163 DOI: 10.1038/Srep40764 |
0.789 |
|
| 2017 |
Lin G, Mao D, Bellen HJ. Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload. Current Topics in Developmental Biology. 121: 111-171. PMID 28057298 DOI: 10.1016/bs.ctdb.2016.07.004 |
0.378 |
|
| 2017 |
Nagarkar-Jaiswal S, Manivannan SN, Zuo Z, Bellen HJ. Author response: A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells Elife. DOI: 10.7554/Elife.26420.018 |
0.781 |
|
| 2016 |
Yoon WH, Sandoval H, Nagarkar-Jaiswal S, Jaiswal M, Yamamoto S, Haelterman NA, Putluri N, Putluri V, Sreekumar A, Tos T, Aksoy A, Donti T, Graham BH, Ohno M, Nishi E, ... ... Bellen HJ, et al. Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. PMID 28017472 DOI: 10.1016/J.Neuron.2016.11.038 |
0.799 |
|
| 2016 |
Chao HT, Davids M, Burke E, Pappas JG, Rosenfeld JA, McCarty AJ, Davis T, Wolfe L, Toro C, Tifft C, Xia F, Stong N, Johnson TK, Warr CG, ... ... Bellen HJ, et al. A Syndromic Neurodevelopmental Disorder Caused by De Novo Variants in EBF3. American Journal of Human Genetics. PMID 28017372 DOI: 10.1016/J.Ajhg.2016.11.018 |
0.753 |
|
| 2016 |
Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals. Elife. 5. PMID 27901468 DOI: 10.7554/Elife.20732 |
0.627 |
|
| 2016 |
Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, ... ... Bellen HJ, et al. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. Plos Genetics. 12: e1006327. PMID 27764101 DOI: 10.1371/Journal.Pgen.1006327 |
0.794 |
|
| 2016 |
Harel T, Yoon WH, Garone C, Gu S, Coban-Akdemir Z, Eldomery MK, Posey JE, Jhangiani SN, Rosenfeld JA, Cho MT, Fox S, Withers M, Brooks SM, Chiang T, Duraine L, ... ... Bellen HJ, et al. Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes. American Journal of Human Genetics. PMID 27640307 DOI: 10.1016/J.Ajhg.2016.08.007 |
0.357 |
|
| 2016 |
Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration. Elife. 5. PMID 27343351 DOI: 10.7554/Elife.16043 |
0.802 |
|
| 2016 |
Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathologica Communications. 4: 62. PMID 27338814 DOI: 10.1186/S40478-016-0333-4 |
0.798 |
|
| 2016 |
Li T, Giagtzoglou N, Eberl D, Nagarkar-Jaiswal S, Cai T, Godt D, Groves AK, Bellen HJ. The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. Elife. 5. PMID 27331610 DOI: 10.7554/Elife.15258 |
0.809 |
|
| 2016 |
Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. Plos Biology. 14: e1002472. PMID 27254664 DOI: 10.1371/Journal.Pbio.1002472 |
0.751 |
|
| 2016 |
Li T, Fan J, Blanco-Sánchez B, Giagtzoglou N, Lin G, Yamamoto S, Jaiswal M, Chen K, Zhang J, Wei W, Lewis MT, Groves AK, Westerfield M, Jia J, Bellen HJ. Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. Plos Genetics. 12: e1006054. PMID 27195754 DOI: 10.1371/Journal.Pgen.1006054 |
0.791 |
|
| 2016 |
Ugur B, Chen K, Bellen HJ. Drosophila tools and assays for the study of human diseases. Disease Models & Mechanisms. 9: 235-44. PMID 26935102 DOI: 10.1242/Dmm.023762 |
0.787 |
|
| 2016 |
Chao YH, Robak LA, Xia F, Koenig MK, Adesina A, Bacino CA, Scaglia F, Bellen HJ, Wangler MF. Missense variants in the middle domain of DNM1L in cases of infantile encephalopathy alter peroxisomes and mitochondria when assayed in Drosophila. Human Molecular Genetics. PMID 26931468 DOI: 10.1093/Hmg/Ddw059 |
0.62 |
|
| 2016 |
David-Morrison G, Xu Z, Rui YN, Charng WL, Jaiswal M, Yamamoto S, Xiong B, Zhang K, Sandoval H, Duraine L, Zuo Z, Zhang S, Bellen HJ. WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. Developmental Cell. 36: 139-51. PMID 26812014 DOI: 10.1016/J.Devcel.2015.12.019 |
0.789 |
|
| 2016 |
Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Author response: Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals Elife. DOI: 10.7554/Elife.20732.015 |
0.572 |
|
| 2016 |
Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Author response: Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration Elife. DOI: 10.7554/Elife.16043.018 |
0.772 |
|
| 2016 |
Li T, Giagtzoglou N, Eberl DF, Jaiswal SN, Cai T, Godt D, Groves AK, Bellen HJ. Author response: The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals Elife. DOI: 10.7554/Elife.15258.017 |
0.782 |
|
| 2015 |
Carrillo RA, Özkan E, Menon KP, Nagarkar-Jaiswal S, Lee PT, Jeon M, Birnbaum ME, Bellen HJ, Garcia KC, Zinn K. Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. Cell. 163: 1770-82. PMID 26687361 DOI: 10.1016/J.Cell.2015.11.022 |
0.804 |
|
| 2015 |
Tan L, Zhang KX, Pecot MY, Nagarkar-Jaiswal S, Lee PT, Takemura SY, McEwen JM, Nern A, Xu S, Tadros W, Chen Z, Zinn K, Bellen HJ, Morey M, Zipursky SL. Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila. Cell. 163: 1756-69. PMID 26687360 DOI: 10.1016/J.Cell.2015.11.021 |
0.801 |
|
| 2015 |
Bellen HJ, Yamamoto S. Morgan's Legacy: Fruit Flies and the Functional Annotation of Conserved Genes. Cell. 163: 12-4. PMID 26406362 DOI: 10.1016/J.Cell.2015.09.009 |
0.483 |
|
| 2015 |
Zanet J, Benrabah E, Li T, Pélissier-Monier A, Chanut-Delalande H, Ronsin B, Bellen HJ, Payre F, Plaza S. Pri sORF peptides induce selective proteasome-mediated protein processing. Science (New York, N.Y.). 349: 1356-8. PMID 26383956 DOI: 10.1126/Science.Aac5677 |
0.647 |
|
| 2015 |
Wang F, Jiang L, Chen Y, Haelterman NA, Bellen HJ, Chen R. FlyVar: a database for genetic variation in Drosophila melanogaster. Database : the Journal of Biological Databases and Curation. 2015. PMID 26289428 DOI: 10.1093/database/bav079 |
0.754 |
|
| 2015 |
Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932 |
0.44 |
|
| 2015 |
Wang S, Bellen HJ. The retromer complex in development and disease. Development (Cambridge, England). 142: 2392-6. PMID 26199408 DOI: 10.1242/dev.123737 |
0.34 |
|
| 2015 |
Jaiswal M, Haelterman NA, Sandoval H, Xiong B, Donti T, Kalsotra A, Yamamoto S, Cooper TA, Graham BH, Bellen HJ. Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress. Plos Biology. 13: e1002197. PMID 26176594 DOI: 10.1371/Journal.Pbio.1002197 |
0.798 |
|
| 2015 |
Nagarkar-Jaiswal S, DeLuca SZ, Lee PT, Lin WW, Pan H, Zuo Z, Lv J, Spradling AC, Bellen HJ. A genetic toolkit for tagging intronic MiMIC containing genes. Elife. 4. PMID 26102525 DOI: 10.7554/Elife.08469 |
0.802 |
|
| 2015 |
Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. Correction: the retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 13: e1002170. PMID 26020534 DOI: 10.1371/Journal.Pbio.1002170 |
0.773 |
|
| 2015 |
Wangler M, Bayat V, Bellen H. A Mitochondrial Translation Defect Identified by Whole-Exome Sequencing Expands the Phenotypic Spectrum for MARS2. Human Mutation. 36: iii. PMID 25989390 DOI: 10.1002/Humu.22811 |
0.786 |
|
| 2015 |
Nagarkar-Jaiswal S, Lee PT, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin WW, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, ... ... Bellen HJ, et al. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife. 4. PMID 25824290 DOI: 10.7554/Elife.05338 |
0.803 |
|
| 2015 |
Tian X, Gala U, Zhang Y, Shang W, Nagarkar Jaiswal S, di Ronza A, Jaiswal M, Yamamoto S, Sandoval H, Duraine L, Sardiello M, Sillitoe RV, Venkatachalam K, Fan H, Bellen HJ, et al. A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. Plos Biology. 13: e1002103. PMID 25811491 DOI: 10.1371/Journal.Pbio.1002103 |
0.708 |
|
| 2015 |
Rui YN, Xu Z, Patel B, Chen Z, Chen D, Tito A, David G, Sun Y, Stimming EF, Bellen HJ, Cuervo AM, Zhang S. Huntingtin functions as a scaffold for selective macroautophagy. Nature Cell Biology. 17: 262-75. PMID 25686248 DOI: 10.1038/Ncb3101 |
0.342 |
|
| 2015 |
Wangler MF, Yamamoto S, Bellen HJ. Fruit flies in biomedical research. Genetics. 199: 639-53. PMID 25624315 DOI: 10.1534/Genetics.114.171785 |
0.634 |
|
| 2015 |
Liu L, Zhang K, Sandoval H, Yamamoto S, Jaiswal M, Sanz E, Li Z, Hui J, Graham BH, Quintana A, Bellen HJ. Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration. Cell. 160: 177-90. PMID 25594180 DOI: 10.1016/J.Cell.2014.12.019 |
0.776 |
|
| 2015 |
Nagarkar-Jaiswal S, Lee P, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin W, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, ... ... Bellen HJ, et al. Author response: A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila Elife. DOI: 10.7554/Elife.05338.023 |
0.597 |
|
| 2014 |
Wong CO, Chen K, Lin YQ, Chao Y, Duraine L, Lu Z, Yoon WH, Sullivan JM, Broadhead GT, Sumner CJ, Lloyd TE, Macleod GT, Bellen HJ, Venkatachalam K. A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron. 84: 764-77. PMID 25451193 DOI: 10.1016/J.Neuron.2014.09.030 |
0.701 |
|
| 2014 |
Sandoval H, Yao CK, Chen K, Jaiswal M, Donti T, Lin YQ, Bayat V, Xiong B, Zhang K, David G, Charng WL, Yamamoto S, Duraine L, Graham BH, Bellen HJ. Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production. Elife. 3. PMID 25313867 DOI: 10.7554/Elife.03558 |
0.792 |
|
| 2014 |
Yamamoto S, Jaiswal M, Charng WL, Gambin T, Karaca E, Mirzaa G, Wiszniewski W, Sandoval H, Haelterman NA, Xiong B, Zhang K, Bayat V, David G, Li T, Chen K, ... ... Bellen HJ, et al. A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 159: 200-14. PMID 25259927 DOI: 10.1016/J.Cell.2014.09.002 |
0.799 |
|
| 2014 |
Haelterman NA, Jiang L, Li Y, Bayat V, Sandoval H, Ugur B, Tan KL, Zhang K, Bei D, Xiong B, Charng WL, Busby T, Jawaid A, David G, Jaiswal M, ... ... Bellen HJ, et al. Large-scale identification of chemically induced mutations in Drosophila melanogaster. Genome Research. 24: 1707-18. PMID 25258387 DOI: 10.1101/Gr.174615.114 |
0.795 |
|
| 2014 |
Yamamoto S, Bellen HJ. Preface. Notch signaling. Methods in Molecular Biology (Clifton, N.J.). 1187: v. PMID 25187920 DOI: 10.1007/978-1-4939-1139_4 |
0.304 |
|
| 2014 |
Halstead JM, Lin YQ, Durraine L, Hamilton RS, Ball G, Neely GG, Bellen HJ, Davis I. Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse. Biology Open. 3: 839-49. PMID 25171887 DOI: 10.1242/bio.20149027 |
0.338 |
|
| 2014 |
Yamamoto S, Schulze KL, Bellen HJ. Introduction to Notch signaling. Methods in Molecular Biology (Clifton, N.J.). 1187: 1-14. PMID 25053477 DOI: 10.1007/978-1-4939-1139-4_1 |
0.716 |
|
| 2014 |
Haelterman NA, Yoon WH, Sandoval H, Jaiswal M, Shulman JM, Bellen HJ. A mitocentric view of Parkinson's disease. Annual Review of Neuroscience. 37: 137-59. PMID 24821430 DOI: 10.1146/Annurev-Neuro-071013-014317 |
0.791 |
|
| 2014 |
Wang S, Tan KL, Agosto MA, Xiong B, Yamamoto S, Sandoval H, Jaiswal M, Bayat V, Zhang K, Charng WL, David G, Duraine L, Venkatachalam K, Wensel TG, Bellen HJ. The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration. Plos Biology. 12: e1001847. PMID 24781186 DOI: 10.1371/Journal.Pbio.1001847 |
0.8 |
|
| 2014 |
Charng WL, Yamamoto S, Bellen HJ. Shared mechanisms between Drosophila peripheral nervous system development and human neurodegenerative diseases. Current Opinion in Neurobiology. 27: 158-64. PMID 24762652 DOI: 10.1016/J.Conb.2014.03.001 |
0.768 |
|
| 2014 |
Venken KJ, Bellen HJ. Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. Methods (San Diego, Calif.). 68: 15-28. PMID 24583113 DOI: 10.1016/j.ymeth.2014.02.025 |
0.613 |
|
| 2014 |
Charng WL, Yamamoto S, Jaiswal M, Bayat V, Xiong B, Zhang K, Sandoval H, David G, Gibbs S, Lu HC, Chen K, Giagtzoglou N, Bellen HJ. Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. Plos Biology. 12: e1001777. PMID 24492843 DOI: 10.1371/Journal.Pbio.1001777 |
0.802 |
|
| 2014 |
Moustaqim-Barrette A, Lin YQ, Pradhan S, Neely GG, Bellen HJ, Tsuda H. The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control. Human Molecular Genetics. 23: 1975-89. PMID 24271015 DOI: 10.1093/hmg/ddt594 |
0.565 |
|
| 2014 |
Sandoval H, Yao C, Chen K, Jaiswal M, Donti T, Lin YQ, Bayat V, Xiong B, Zhang K, David G, Charng W, Yamamoto S, Duraine L, Graham BH, Bellen HJ. Author response: Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production Elife. DOI: 10.7554/Elife.03558.023 |
0.778 |
|
| 2013 |
Cassidy JJ, Jha AR, Posadas DM, Giri R, Venken KJ, Ji J, Jiang H, Bellen HJ, White KP, Carthew RW. miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor. Cell. 155: 1556-67. PMID 24360277 DOI: 10.1016/J.Cell.2013.10.057 |
0.58 |
|
| 2013 |
Han SM, El Oussini H, Scekic-Zahirovic J, Vibbert J, Cottee P, Prasain JK, Bellen HJ, Dupuis L, Miller MA. VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans. Plos Genetics. 9: e1003738. PMID 24039594 DOI: 10.1371/Journal.Pgen.1003738 |
0.312 |
|
| 2013 |
Xiong B, Bellen HJ. Rhodopsin homeostasis and retinal degeneration: lessons from the fly. Trends in Neurosciences. 36: 652-60. PMID 24012059 DOI: 10.1016/J.Tins.2013.08.003 |
0.507 |
|
| 2013 |
Ali YO, Li-Kroeger D, Bellen HJ, Zhai RG, Lu HC. NMNATs, evolutionarily conserved neuronal maintenance factors. Trends in Neurosciences. 36: 632-40. PMID 23968695 DOI: 10.1016/J.Tins.2013.07.002 |
0.774 |
|
| 2013 |
Yamamoto S, Bayat V, Bellen HJ, Tan C. Protein phosphatase 1ß limits ring canal constriction during Drosophila germline cyst formation. Plos One. 8: e70502. PMID 23936219 DOI: 10.1371/Journal.Pone.0070502 |
0.766 |
|
| 2013 |
Giagtzoglou N, Li T, Yamamoto S, Bellen HJ. Drosophila EHBP1 regulates Scabrous secretion during Notch-mediated lateral inhibition. Journal of Cell Science. 126: 3686-96. PMID 23788431 DOI: 10.1242/Jcs.126292 |
0.79 |
|
| 2013 |
Zhang K, Li Z, Jaiswal M, Bayat V, Xiong B, Sandoval H, Charng WL, David G, Haueter C, Yamamoto S, Graham BH, Bellen HJ. The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit. The Journal of Cell Biology. 200: 807-20. PMID 23509070 DOI: 10.1083/Jcb.201208033 |
0.797 |
|
| 2013 |
Winther Ã…M, Jiao W, Vorontsova O, Rees KA, Koh TW, Sopova E, Schulze KL, Bellen HJ, Shupliakov O. The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses. Journal of Cell Science. 126: 1021-31. PMID 23321638 DOI: 10.1242/Jcs.118968 |
0.798 |
|
| 2012 |
Xiong B, Bayat V, Jaiswal M, Zhang K, Sandoval H, Charng WL, Li T, David G, Duraine L, Lin YQ, Neely GG, Yamamoto S, Bellen HJ. Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells. Plos Biology. 10: e1001438. PMID 23226104 DOI: 10.1371/Journal.Pbio.1001438 |
0.79 |
|
| 2012 |
Yamamoto S, Charng WL, Rana NA, Kakuda S, Jaiswal M, Bayat V, Xiong B, Zhang K, Sandoval H, David G, Wang H, Haltiwanger RS, Bellen HJ. A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands. Science (New York, N.Y.). 338: 1229-32. PMID 23197537 DOI: 10.1126/Science.1228745 |
0.792 |
|
| 2012 |
Chen YC, Lin YQ, Banerjee S, Venken K, Li J, Ismat A, Chen K, Duraine L, Bellen HJ, Bhat MA. Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16018-30. PMID 23136438 DOI: 10.1523/Jneurosci.1685-12.2012 |
0.802 |
|
| 2012 |
Jaiswal M, Sandoval H, Zhang K, Bayat V, Bellen HJ. Probing mechanisms that underlie human neurodegenerative diseases in Drosophila. Annual Review of Genetics. 46: 371-96. PMID 22974305 DOI: 10.1146/Annurev-Genet-110711-155456 |
0.814 |
|
| 2012 |
Szabad J, Bellen HJ, Venken KJ. An assay to detect in vivo Y chromosome loss in Drosophila wing disc cells. G3 (Bethesda, Md.). 2: 1095-102. PMID 22973547 DOI: 10.1534/g3.112.002899 |
0.608 |
|
| 2012 |
Alves-Silva J, Sánchez-Soriano N, Beaven R, Klein M, Parkin J, Millard TH, Bellen HJ, Venken KJ, Ballestrem C, Kammerer RA, Prokop A. Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9143-58. PMID 22764224 DOI: 10.1523/Jneurosci.0416-12.2012 |
0.61 |
|
| 2012 |
Bayat V, Thiffault I, Jaiswal M, Tétreault M, Donti T, Sasarman F, Bernard G, Demers-Lamarche J, Dicaire MJ, Mathieu J, Vanasse M, Bouchard JP, Rioux MF, Lourenco CM, Li Z, ... ... Bellen HJ, et al. Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans. Plos Biology. 10: e1001288. PMID 22448145 DOI: 10.1371/Journal.Pbio.1001288 |
0.82 |
|
| 2012 |
Venken KJ, Bellen HJ. Genome-wide manipulations of Drosophila melanogaster with transposons, Flp recombinase, and ΦC31 integrase. Methods in Molecular Biology (Clifton, N.J.). 859: 203-28. PMID 22367874 DOI: 10.1007/978-1-61779-603-6_12 |
0.588 |
|
| 2012 |
Han SM, Tsuda H, Yang Y, Vibbert J, Cottee P, Lee SJ, Winek J, Haueter C, Bellen HJ, Miller MA. Secreted VAPB/ALS8 major sperm protein domains modulate mitochondrial localization and morphology via growth cone guidance receptors. Developmental Cell. 22: 348-62. PMID 22264801 DOI: 10.1016/J.Devcel.2011.12.009 |
0.548 |
|
| 2012 |
Giagtzoglou N, Yamamoto S, Zitserman D, Graves HK, Schulze KL, Wang H, Klein H, Roegiers F, Bellen HJ. dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions. The Journal of Cell Biology. 196: 65-83. PMID 22213802 DOI: 10.1083/Jcb.201106088 |
0.804 |
|
| 2012 |
Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 190: 931-40. PMID 22174071 DOI: 10.1534/Genetics.111.136465 |
0.672 |
|
| 2011 |
Xue M, Giagtzoglou N, Bellen HJ. Dueling Ca2+ sensors in neurotransmitter release. Cell. 147: 491-3. PMID 22036557 DOI: 10.1016/J.Cell.2011.10.007 |
0.696 |
|
| 2011 |
Venken KJ, Simpson JH, Bellen HJ. Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron. 72: 202-30. PMID 22017985 DOI: 10.1016/j.neuron.2011.09.021 |
0.654 |
|
| 2011 |
Venken KJ, Schulze KL, Haelterman NA, Pan H, He Y, Evans-Holm M, Carlson JW, Levis RW, Spradling AC, Hoskins RA, Bellen HJ. MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. Nature Methods. 8: 737-43. PMID 21985007 DOI: 10.1038/Nmeth.1662 |
0.802 |
|
| 2011 |
Zheng L, Michelson Y, Freger V, Avraham Z, Venken KJ, Bellen HJ, Justice MJ, Wides R. Drosophila Ten-m and filamin affect motor neuron growth cone guidance. Plos One. 6: e22956. PMID 21857973 DOI: 10.1371/Journal.Pone.0022956 |
0.607 |
|
| 2011 |
Tong C, Ohyama T, Tien AC, Rajan A, Haueter CM, Bellen HJ. Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6. Neuron. 71: 447-59. PMID 21835342 DOI: 10.1016/J.Neuron.2011.06.040 |
0.782 |
|
| 2011 |
Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Human Molecular Genetics. 20: 3642-52. PMID 21685205 DOI: 10.1093/Hmg/Ddr284 |
0.547 |
|
| 2011 |
Bellen HJ, Levis RW, He Y, Carlson JW, Evans-Holm M, Bae E, Kim J, Metaxakis A, Savakis C, Schulze KL, Hoskins RA, Spradling AC. The Drosophila gene disruption project: progress using transposons with distinctive site specificities. Genetics. 188: 731-43. PMID 21515576 DOI: 10.1534/Genetics.111.126995 |
0.684 |
|
| 2011 |
Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, ... ... Bellen H, et al. A cis-regulatory map of the Drosophila genome. Nature. 471: 527-31. PMID 21430782 DOI: 10.1038/Nature09990 |
0.579 |
|
| 2011 |
Bayat V, Jaiswal M, Bellen HJ. The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases. Current Opinion in Neurobiology. 21: 182-8. PMID 20832291 DOI: 10.1016/J.Conb.2010.08.014 |
0.794 |
|
| 2010 |
Neely GG, Hess A, Costigan M, Keene AC, Goulas S, Langeslag M, Griffin RS, Belfer I, Dai F, Smith SB, Diatchenko L, Gupta V, Xia CP, Amann S, Kreitz S, ... ... Bellen HJ, et al. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 143: 628-38. PMID 21074052 DOI: 10.1016/J.Cell.2010.09.047 |
0.623 |
|
| 2010 |
Venken KJ, Popodi E, Holtzman SL, Schulze KL, Park S, Carlson JW, Hoskins RA, Bellen HJ, Kaufman TC. A molecularly defined duplication set for the X chromosome of Drosophila melanogaster. Genetics. 186: 1111-25. PMID 20876565 DOI: 10.1534/Genetics.110.121285 |
0.75 |
|
| 2010 |
Yamamoto S, Charng WL, Bellen HJ. Endocytosis and intracellular trafficking of Notch and its ligands. Current Topics in Developmental Biology. 92: 165-200. PMID 20816395 DOI: 10.1016/S0070-2153(10)92005-X |
0.746 |
|
| 2010 |
Bellen HJ, Tong C, Tsuda H. 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. Nature Reviews. Neuroscience. 11: 514-22. PMID 20383202 DOI: 10.1038/Nrn2839 |
0.488 |
|
| 2009 |
Giagtzoglou N, Ly CV, Bellen HJ. Cell adhesion, the backbone of the synapse: "vertebrate" and "invertebrate" perspectives. Cold Spring Harbor Perspectives in Biology. 1: a003079. PMID 20066100 DOI: 10.1101/Cshperspect.A003079 |
0.794 |
|
| 2009 |
Giagtzoglou N, Mahoney T, Yao CK, Bellen HJ. Rab3 GTPase lands Bruchpilot. Neuron. 64: 595-7. PMID 20005815 DOI: 10.1016/J.Neuron.2009.11.029 |
0.791 |
|
| 2009 |
Xue M, Lin YQ, Pan H, Reim K, Deng H, Bellen HJ, Rosenmund C. Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis. Neuron. 64: 367-80. PMID 19914185 DOI: 10.1016/j.neuron.2009.09.043 |
0.607 |
|
| 2009 |
Yao CK, Lin YQ, Ly CV, Ohyama T, Haueter CM, Moiseenkova-Bell VY, Wensel TG, Bellen HJ. A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. Cell. 138: 947-60. PMID 19737521 DOI: 10.1016/J.Cell.2009.06.033 |
0.722 |
|
| 2009 |
Verstreken P, Ohyama T, Haueter C, Habets RL, Lin YQ, Swan LE, Ly CV, Venken KJ, De Camilli P, Bellen HJ. Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron. 63: 203-15. PMID 19640479 DOI: 10.1016/J.Neuron.2009.06.017 |
0.793 |
|
| 2009 |
Patel PH, Costa-Mattioli M, Schulze KL, Bellen HJ. The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. The Journal of Cell Biology. 185: 1181-94. PMID 19546244 DOI: 10.1083/Jcb.200904161 |
0.769 |
|
| 2009 |
Rajan A, Tien AC, Haueter CM, Schulze KL, Bellen HJ. The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. Nature Cell Biology. 11: 815-24. PMID 19543274 DOI: 10.1038/Ncb1888 |
0.802 |
|
| 2009 |
Fotowat H, Fayyazuddin A, Bellen HJ, Gabbiani F. A novel neuronal pathway for visually guided escape in Drosophila melanogaster. Journal of Neurophysiology. 102: 875-85. PMID 19474177 DOI: 10.1152/Jn.00073.2009 |
0.706 |
|
| 2009 |
Venken KJ, Carlson JW, Schulze KL, Pan H, He Y, Spokony R, Wan KH, Koriabine M, de Jong PJ, White KP, Bellen HJ, Hoskins RA. Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nature Methods. 6: 431-4. PMID 19465919 DOI: 10.1038/Nmeth.1331 |
0.758 |
|
| 2009 |
Andrews HK, Giagtzoglou N, Yamamoto S, Schulze KL, Bellen HJ. Sequoia regulates cell fate decisions in the external sensory organs of adult Drosophila. Embo Reports. 10: 636-41. PMID 19444309 DOI: 10.1038/Embor.2009.66 |
0.804 |
|
| 2009 |
Giagtzoglou N, Lin YQ, Haueter C, Bellen HJ. Importin 13 regulates neurotransmitter release at the Drosophila neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5628-39. PMID 19403829 DOI: 10.1523/Jneurosci.0794-09.2009 |
0.733 |
|
| 2009 |
Tien AC, Rajan A, Bellen HJ. A Notch updated. The Journal of Cell Biology. 184: 621-9. PMID 19255248 DOI: 10.1083/Jcb.200811141 |
0.697 |
|
| 2008 |
Tien AC, Rajan A, Schulze KL, Ryoo HD, Acar M, Steller H, Bellen HJ. Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. The Journal of Cell Biology. 182: 1113-25. PMID 18809725 DOI: 10.1083/Jcb.200805001 |
0.809 |
|
| 2008 |
Tsuda H, Han SM, Yang Y, Tong C, Lin YQ, Mohan K, Haueter C, Zoghbi A, Harati Y, Kwan J, Miller MA, Bellen HJ. The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell. 133: 963-77. PMID 18555774 DOI: 10.1016/J.Cell.2008.04.039 |
0.526 |
|
| 2008 |
Ly CV, Yao CK, Verstreken P, Ohyama T, Bellen HJ. straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel alpha1 subunit. The Journal of Cell Biology. 181: 157-70. PMID 18391075 DOI: 10.1083/Jcb.200712152 |
0.799 |
|
| 2008 |
Verstreken P, Ohyama T, Bellen HJ. FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. Methods in Molecular Biology (Clifton, N.J.). 440: 349-69. PMID 18369958 DOI: 10.1007/978-1-59745-178-9_26 |
0.761 |
|
| 2008 |
Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature. 452: 887-91. PMID 18344983 DOI: 10.1038/nature06721 |
0.734 |
|
| 2008 |
Acar M, Jafar-Nejad H, Takeuchi H, Rajan A, Ibrani D, Rana NA, Pan H, Haltiwanger RS, Bellen HJ. Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. Cell. 132: 247-58. PMID 18243100 DOI: 10.1016/J.Cell.2007.12.016 |
0.787 |
|
| 2008 |
Romero E, Cha GH, Verstreken P, Ly CV, Hughes RE, Bellen HJ, Botas J. Suppression of neurodegeneration and increased neurotransmission caused by expanded full-length huntingtin accumulating in the cytoplasm. Neuron. 57: 27-40. PMID 18184562 DOI: 10.1016/J.Neuron.2007.11.025 |
0.787 |
|
| 2008 |
Zhang W, Wang D, Volk E, Bellen HJ, Hiesinger PR, Quiocho FA. V-ATPase V0 sector subunit a1 in neurons is a target of calmodulin. The Journal of Biological Chemistry. 283: 294-300. PMID 17933871 DOI: 10.1074/Jbc.M708058200 |
0.685 |
|
| 2007 |
Ohyama T, Verstreken P, Ly CV, Rosenmund T, Rajan A, Tien AC, Haueter C, Schulze KL, Bellen HJ. Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles. The Journal of Cell Biology. 179: 1481-96. PMID 18158335 DOI: 10.1083/Jcb.200710061 |
0.801 |
|
| 2007 |
Venken KJ, Bellen HJ. Transgenesis upgrades for Drosophila melanogaster. Development (Cambridge, England). 134: 3571-84. PMID 17905790 DOI: 10.1242/dev.005686 |
0.615 |
|
| 2007 |
Koh TW, Korolchuk VI, Wairkar YP, Jiao W, Evergren E, Pan H, Zhou Y, Venken KJ, Shupliakov O, Robinson IM, O'Kane CJ, Bellen HJ. Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. The Journal of Cell Biology. 178: 309-22. PMID 17620409 DOI: 10.1083/jcb.200701030 |
0.807 |
|
| 2007 |
Zhang J, Schulze KL, Hiesinger PR, Suyama K, Wang S, Fish M, Acar M, Hoskins RA, Bellen HJ, Scott MP. Thirty-one flavors of Drosophila rab proteins. Genetics. 176: 1307-22. PMID 17409086 DOI: 10.1534/Genetics.106.066761 |
0.811 |
|
| 2007 |
Bellen HJ, Acar M, Nejad HJ, Tien A, Rajan A. Novel players in the Notch signalling pathway Developmental Biology. 306: 301. DOI: 10.1016/J.Ydbio.2007.03.082 |
0.727 |
|
| 2006 |
Venken KJ, He Y, Hoskins RA, Bellen HJ. P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster. Science (New York, N.Y.). 314: 1747-51. PMID 17138868 DOI: 10.1126/science.1134426 |
0.6 |
|
| 2006 |
Zhai RG, Cao Y, Hiesinger PR, Zhou Y, Mehta SQ, Schulze KL, Verstreken P, Bellen HJ. Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. Plos Biology. 4: e416. PMID 17132048 DOI: 10.1371/journal.pbio.0040416 |
0.816 |
|
| 2006 |
Hiesinger PR, Zhai RG, Zhou Y, Koh TW, Mehta SQ, Schulze KL, Cao Y, Verstreken P, Clandinin TR, Fischbach KF, Meinertzhagen IA, Bellen HJ. Activity-independent prespecification of synaptic partners in the visual map of Drosophila. Current Biology : Cb. 16: 1835-43. PMID 16979562 DOI: 10.1016/j.cub.2006.07.047 |
0.796 |
|
| 2006 |
Acar M, Jafar-Nejad H, Giagtzoglou N, Yallampalli S, David G, He Y, Delidakis C, Bellen HJ. Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development (Cambridge, England). 133: 1979-89. PMID 16624856 DOI: 10.1242/Dev.02372 |
0.802 |
|
| 2006 |
Seto ES, Bellen HJ. Internalization is required for proper Wingless signaling in Drosophila melanogaster. The Journal of Cell Biology. 173: 95-106. PMID 16606693 DOI: 10.1083/jcb.200510123 |
0.565 |
|
| 2006 |
Jafar-Nejad H, Tien AC, Acar M, Bellen HJ. Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin. Development (Cambridge, England). 133: 1683-92. PMID 16554363 DOI: 10.1242/Dev.02338 |
0.823 |
|
| 2006 |
Fayyazuddin A, Zaheer MA, Hiesinger PR, Bellen HJ. The nicotinic acetylcholine receptor Dalpha7 is required for an escape behavior in Drosophila. Plos Biology. 4: e63. PMID 16494528 DOI: 10.1371/journal.pbio.0040063 |
0.784 |
|
| 2006 |
Giagtzoglou N, Bellen HJ. Fighting anthrax with flies. Proceedings of the National Academy of Sciences of the United States of America. 103: 3013-4. PMID 16492749 DOI: 10.1073/Pnas.0600477103 |
0.714 |
|
| 2005 |
Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes & Development. 19: 2412-7. PMID 16230531 DOI: 10.1101/gad.1353905 |
0.672 |
|
| 2005 |
Jafar-Nejad H, Andrews HK, Acar M, Bayat V, Wirtz-Peitz F, Mehta SQ, Knoblich JA, Bellen HJ. Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Developmental Cell. 9: 351-63. PMID 16137928 DOI: 10.1016/J.Devcel.2005.06.010 |
0.814 |
|
| 2005 |
Tsuda H, Jafar-Nejad H, Patel AJ, Sun Y, Chen HK, Rose MF, Venken KJ, Botas J, Orr HT, Bellen HJ, Zoghbi HY. The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell. 122: 633-44. PMID 16122429 DOI: 10.1016/J.Cell.2005.06.012 |
0.809 |
|
| 2005 |
Verstreken P, Ly CV, Venken KJ, Koh TW, Zhou Y, Bellen HJ. Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron. 47: 365-78. PMID 16055061 DOI: 10.1016/J.Neuron.2005.06.018 |
0.807 |
|
| 2005 |
Dermaut B, Norga KK, Kania A, Verstreken P, Pan H, Zhou Y, Callaerts P, Bellen HJ. Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. The Journal of Cell Biology. 170: 127-39. PMID 15998804 DOI: 10.1083/Jcb.200412001 |
0.815 |
|
| 2005 |
Hiesinger PR, Fayyazuddin A, Mehta SQ, Rosenmund T, Schulze KL, Zhai RG, Verstreken P, Cao Y, Zhou Y, Kunz J, Bellen HJ. The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila. Cell. 121: 607-20. PMID 15907473 DOI: 10.1016/J.Cell.2005.03.012 |
0.797 |
|
| 2005 |
Mehta SQ, Hiesinger PR, Beronja S, Zhai RG, Schulze KL, Verstreken P, Cao Y, Zhou Y, Tepass U, Crair MC, Bellen HJ. Mutations in Drosophila sec15 reveal a function in neuronal targeting for a subset of exocyst components. Neuron. 46: 219-32. PMID 15848801 DOI: 10.1016/j.neuron.2005.02.029 |
0.818 |
|
| 2005 |
Venken KJ, Bellen HJ. Emerging technologies for gene manipulation in Drosophila melanogaster. Nature Reviews. Genetics. 6: 167-78. PMID 15738961 DOI: 10.1038/nrg1553 |
0.599 |
|
| 2005 |
Escudero LM, Caminero E, Schulze KL, Bellen HJ, Modolell J. Charlatan, a Zn-finger transcription factor, establishes a novel level of regulation of the proneural achaete/scute genes of Drosophila. Development (Cambridge, England). 132: 1211-22. PMID 15703278 DOI: 10.1242/Dev.01691 |
0.673 |
|
| 2005 |
Beckstead RB, Ner SS, Hales KG, Grigliatti TA, Baker BS, Bellen HJ. Bonus, a Drosophila TIF1 homolog, is a chromatin-associated protein that acts as a modifier of position-effect variegation. Genetics. 169: 783-94. PMID 15545640 DOI: 10.1534/genetics.104.037085 |
0.664 |
|
| 2004 |
Kazanjian A, Wallis D, Au N, Nigam R, Venken KJ, Cagle PT, Dickey BF, Bellen HJ, Gilks CB, Grimes HL. Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells. Cancer Research. 64: 6874-82. PMID 15466176 DOI: 10.1158/0008-5472.CAN-04-0633 |
0.581 |
|
| 2004 |
Zhai RG, Bellen HJ. Hauling t-SNAREs on the microtubule highway. Nature Cell Biology. 6: 918-9. PMID 15459718 DOI: 10.1038/ncb1004-918 |
0.473 |
|
| 2004 |
Jafar-Nejad H, Bellen HJ. Gfi/Pag-3/senseless zinc finger proteins: a unifying theme? Molecular and Cellular Biology. 24: 8803-12. PMID 15456856 DOI: 10.1128/Mcb.24.20.8803-8812.2004 |
0.705 |
|
| 2004 |
Zhai RG, Bellen HJ. The architecture of the active zone in the presynaptic nerve terminal. Physiology (Bethesda, Md.). 19: 262-70. PMID 15381754 DOI: 10.1152/physiol.00014.2004 |
0.458 |
|
| 2004 |
Koh TW, Verstreken P, Bellen HJ. Dap160/intersectin acts as a stabilizing scaffold required for synaptic development and vesicle endocytosis. Neuron. 43: 193-205. PMID 15260956 DOI: 10.1016/J.Neuron.2004.06.029 |
0.818 |
|
| 2004 |
Bellen HJ, Levis RW, Liao G, He Y, Carlson JW, Tsang G, Evans-Holm M, Hiesinger PR, Schulze KL, Rubin GM, Hoskins RA, Spradling AC. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics. 167: 761-81. PMID 15238527 DOI: 10.1534/Genetics.104.026427 |
0.796 |
|
| 2004 |
Pesah Y, Pham T, Burgess H, Middlebrooks B, Verstreken P, Zhou Y, Harding M, Bellen H, Mardon G. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development (Cambridge, England). 131: 2183-94. PMID 15073152 DOI: 10.1242/dev.01095 |
0.735 |
|
| 2004 |
Hiesinger PR, Bellen HJ. Flying in the face of total disruption. Nature Genetics. 36: 211-2. PMID 14988715 DOI: 10.1038/ng0304-211 |
0.659 |
|
| 2004 |
Seto ES, Bellen HJ. The ins and outs of Wingless signaling. Trends in Cell Biology. 14: 45-53. PMID 14729180 DOI: 10.1016/j.tcb.2003.11.004 |
0.543 |
|
| 2003 |
Jafar-Nejad H, Acar M, Nolo R, Lacin H, Pan H, Parkhurst SM, Bellen HJ. Senseless acts as a binary switch during sensory organ precursor selection. Genes & Development. 17: 2966-78. PMID 14665671 DOI: 10.1101/Gad.1122403 |
0.789 |
|
| 2003 |
Fabian-Fine R, Verstreken P, Hiesinger PR, Horne JA, Kostyleva R, Zhou Y, Bellen HJ, Meinertzhagen IA. Endophilin promotes a late step in endocytosis at glial invaginations in Drosophila photoreceptor terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10732-44. PMID 14627659 DOI: 10.1523/Jneurosci.23-33-10732.2003 |
0.804 |
|
| 2003 |
Verstreken P, Koh TW, Schulze KL, Zhai RG, Hiesinger PR, Zhou Y, Mehta SQ, Cao Y, Roos J, Bellen HJ. Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron. 40: 733-48. PMID 14622578 DOI: 10.1016/S0896-6273(03)00644-5 |
0.805 |
|
| 2003 |
Zhai RG, Hiesinger PR, Koh TW, Verstreken P, Schulze KL, Cao Y, Jafar-Nejad H, Norga KK, Pan H, Bayat V, Greenbaum MP, Bellen HJ. Mapping Drosophila mutations with molecularly defined P element insertions. Proceedings of the National Academy of Sciences of the United States of America. 100: 10860-5. PMID 12960394 DOI: 10.1073/Pnas.1832753100 |
0.773 |
|
| 2003 |
Norga KK, Gurganus MC, Dilda CL, Yamamoto A, Lyman RF, Patel PH, Rubin GM, Hoskins RA, Mackay TF, Bellen HJ. Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Current Biology : Cb. 13: 1388-96. PMID 12932322 DOI: 10.1016/S0960-9822(03)00546-3 |
0.796 |
|
| 2003 |
Koh TW, Bellen HJ. Synaptotagmin I, a Ca2+ sensor for neurotransmitter release. Trends in Neurosciences. 26: 413-22. PMID 12900172 DOI: 10.1016/S0166-2236(03)00195-4 |
0.669 |
|
| 2003 |
Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ. The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development (Cambridge, England). 130: 221-32. PMID 12441305 DOI: 10.1242/Dev.00190 |
0.69 |
|
| 2003 |
Bhat MA, Izaddoost S, Lu Y, Cho KO, Choi KW, Bellen HJ. Erratum: Discs lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity (Cell (1999) 96 (833-845)) Cell. 115: 765-766. DOI: 10.1016/S0092-8674(03)00973-5 |
0.536 |
|
| 2003 |
Bellen HJ, Schulze KL. Invertebrate Glia Myelin Biology and Disorders. 1: 199-222. DOI: 10.1016/B978-012439510-7/50061-9 |
0.615 |
|
| 2002 |
Kango-Singh M, Nolo R, Tao C, Verstreken P, Hiesinger PR, Bellen HJ, Halder G. Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development (Cambridge, England). 129: 5719-30. PMID 12421711 DOI: 10.1242/Dev.00168 |
0.792 |
|
| 2002 |
Kjaerulff O, Verstreken P, Bellen HJ. Synaptic vesicle retrieval: still time for a kiss. Nature Cell Biology. 4: E245-8. PMID 12415277 DOI: 10.1038/ncb1102-e245 |
0.79 |
|
| 2002 |
Wang VY, Hassan BA, Bellen HJ, Zoghbi HY. Drosophila atonal fully rescues the phenotype of Math1 null mice: new functions evolve in new cellular contexts. Current Biology : Cb. 12: 1611-6. PMID 12372255 DOI: 10.1016/S0960-9822(02)01144-2 |
0.699 |
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| 2002 |
Jafar-Nejad H, Norga K, Bellen H. Numb: "Adapting" notch for endocytosis. Developmental Cell. 3: 155-6. PMID 12194846 DOI: 10.1016/S1534-5807(02)00228-9 |
0.789 |
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| 2002 |
Pennetta G, Hiesinger PR, Fabian-Fine R, Meinertzhagen IA, Bellen HJ. Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner. Neuron. 35: 291-306. PMID 12160747 DOI: 10.1016/S0896-6273(02)00769-9 |
0.783 |
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| 2002 |
Verstreken P, Bellen HJ. Meaningless minis? Mechanisms of neurotransmitter-receptor clustering. Trends in Neurosciences. 25: 383-5. PMID 12127745 DOI: 10.1016/S0166-2236(02)02197-5 |
0.679 |
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| 2002 |
Seto ES, Bellen HJ, Lloyd TE. When cell biology meets development: endocytic regulation of signaling pathways. Genes & Development. 16: 1314-36. PMID 12050111 DOI: 10.1101/gad.989602 |
0.662 |
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| 2002 |
Verstreken P, Kjaerulff O, Lloyd TE, Atkinson R, Zhou Y, Meinertzhagen IA, Bellen HJ. Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell. 109: 101-12. PMID 11955450 DOI: 10.1016/S0092-8674(02)00688-8 |
0.805 |
|
| 2002 |
Izaddoost S, Nam SC, Bhat MA, Bellen HJ, Choi KW. Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres. Nature. 416: 178-83. PMID 11850624 DOI: 10.1038/nature720 |
0.673 |
|
| 2002 |
Lloyd TE, Atkinson R, Wu MN, Zhou Y, Pennetta G, Bellen HJ. Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell. 108: 261-9. PMID 11832215 DOI: 10.1016/S0092-8674(02)00611-6 |
0.78 |
|
| 2002 |
Chen S, Zheng X, Schulze KL, Morris T, Bellen H, Stanley EF. Enhancement of presynaptic calcium current by cysteine string protein. The Journal of Physiology. 538: 383-9. PMID 11790807 DOI: 10.1113/jphysiol.2001.013397 |
0.656 |
|
| 2001 |
Fergestad T, Wu MN, Schulze KL, Lloyd TE, Bellen HJ, Broadie K. Targeted mutations in the syntaxin H3 domain specifically disrupt SNARE complex function in synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9142-50. PMID 11717347 DOI: 10.1523/Jneurosci.21-23-09142.2001 |
0.795 |
|
| 2001 |
Frankfort BJ, Nolo R, Zhang Z, Bellen H, Mardon G. senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye. Neuron. 32: 403-14. PMID 11709152 DOI: 10.1016/S0896-6273(01)00480-9 |
0.769 |
|
| 2001 |
Lloyd TE, Bellen HJ. pRIMing synaptic vesicles for fusion. Nature Neuroscience. 4: 965-6. PMID 11574826 DOI: 10.1038/nn1001-965 |
0.56 |
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| 2001 |
Verstreken P, Bellen HJ. Neuroscience. The meaning of a mini. Science (New York, N.Y.). 293: 443-4. PMID 11463902 DOI: 10.1126/science.1063293 |
0.701 |
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| 2001 |
Bermingham NA, Hassan BA, Wang VY, Fernandez M, Banfi S, Bellen HJ, Fritzsch B, Zoghbi HY. Proprioceptor pathway development is dependent on Math1. Neuron. 30: 411-22. PMID 11395003 DOI: 10.1016/S0896-6273(01)00305-1 |
0.679 |
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| 2001 |
Bhat MA, Rios JC, Lu Y, Garcia-Fresco GP, Ching W, St Martin M, Li J, Einheber S, Chesler M, Rosenbluth J, Salzer JL, Bellen HJ. Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin. Neuron. 30: 369-83. PMID 11395000 DOI: 10.1016/S0896-6273(01)00294-X |
0.774 |
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| 2001 |
Beckstead R, Ortiz JA, Sanchez C, Prokopenko SN, Chambon P, Losson R, Bellen HJ. Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription. Molecular Cell. 7: 753-65. PMID 11336699 DOI: 10.1016/S1097-2765(01)00220-9 |
0.762 |
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| 2001 |
Wu MN, Schulze KL, Lloyd TE, Bellen HJ. The ROP-syntaxin interaction inhibits neurotransmitter release. European Journal of Cell Biology. 80: 196-9. PMID 11302525 DOI: 10.1078/0171-9335-00143 |
0.739 |
|
| 2001 |
Steffensen S, Coelho PA, Cobbe N, Vass S, Costa M, Hassan B, Prokopenko SN, Bellen H, Heck MM, Sunkel CE. A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Current Biology : Cb. 11: 295-307. PMID 11267866 DOI: 10.1016/S0960-9822(01)00096-3 |
0.709 |
|
| 2001 |
Nolo R, Abbott LA, Bellen HJ. Drosophila Lyra mutations are gain-of-function mutations of senseless. Genetics. 157: 307-15. PMID 11139511 |
0.815 |
|
| 2001 |
Lloyd TE, Atkinson RA, Wu MN, Bellen HJ. HRS regulates endosomal trafficking and tyrosine kinase receptor signaling Biochemical Society Transactions. 29: A84-A84. DOI: 10.1042/BST029A084B |
0.594 |
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| 2000 |
Prokopenko SN, He Y, Lu Y, Bellen HJ. Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics. 156: 1691-715. PMID 11102367 |
0.613 |
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| 2000 |
Nolo R, Abbott LA, Bellen HJ. Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell. 102: 349-62. PMID 10975525 DOI: 10.1016/S0092-8674(00)00040-4 |
0.802 |
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| 2000 |
Hassan BA, Bellen HJ. Doing the MATH: is the mouse a good model for fly development? Genes & Development. 14: 1852-65. PMID 10921900 DOI: 10.1101/Gad.14.15.1852 |
0.595 |
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| 2000 |
Lloyd TE, Verstreken P, Ostrin EJ, Phillippi A, Lichtarge O, Bellen HJ. A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron. 26: 45-50. PMID 10798391 DOI: 10.1016/S0896-6273(00)81136-8 |
0.78 |
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| 2000 |
Hassan BA, Bermingham NA, He Y, Sun Y, Jan YN, Zoghbi HY, Bellen HJ. atonal regulates neurite arborization but does not act as a proneural gene in the Drosophila brain. Neuron. 25: 549-61. PMID 10774724 DOI: 10.1016/S0896-6273(00)81059-4 |
0.69 |
|
| 2000 |
Prokopenko SN, Saint R, Bellen HJ. Untying the Gordian knot of cytokinesis. Role of small G proteins and their regulators. The Journal of Cell Biology. 148: 843-8. PMID 10704435 DOI: 10.1083/Jcb.148.5.843 |
0.615 |
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| 2000 |
Mao Y, Nickitenko A, Duan X, Lloyd TE, Wu MN, Bellen H, Quiocho FA. Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Cell. 100: 447-56. PMID 10693761 DOI: 10.1016/S0092-8674(00)80680-7 |
0.595 |
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| 2000 |
Ben-Arie N, Hassan BA, Bermingham NA, Malicki DM, Armstrong D, Matzuk M, Bellen HJ, Zoghbi HY. Functional conservation of atonal and Math1 in the CNS and PNS. Development (Cambridge, England). 127: 1039-48. PMID 10662643 |
0.664 |
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| 2000 |
Prokopenko SN, Saint R, Bellen HJ. Tissue distribution of PEBBLE RNA and pebble protein during Drosophila embryonic development. Mechanisms of Development. 90: 269-73. PMID 10640710 DOI: 10.1016/S0925-4773(99)00233-6 |
0.628 |
|
| 2000 |
Cobbe N, Steffensen S, Vass S, Coelho P, Hassan B, Bellen H, Sunkel C, Heck MS. Mutations in the Drosophila SMC4 gene are associated with abnormal mitotic chromosome segregation Biochemical Society Transactions. 28: A246-A246. DOI: 10.1042/Bst028A246A |
0.314 |
|
| 1999 |
Bellen HJ. Ten years of enhancer detection: lessons from the fly. The Plant Cell. 11: 2271-81. PMID 10590157 DOI: 10.1105/tpc.11.12.2271 |
0.323 |
|
| 1999 |
Prokopenko SN, Brumby A, O'Keefe L, Prior L, He Y, Saint R, Bellen HJ. A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila. Genes & Development. 13: 2301-14. PMID 10485851 DOI: 10.1101/gad.13.17.2301 |
0.651 |
|
| 1999 |
Wu MN, Fergestad T, Lloyd TE, He Y, Broadie K, Bellen HJ. Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo. Neuron. 23: 593-605. PMID 10433270 DOI: 10.1016/S0896-6273(00)80811-9 |
0.635 |
|
| 1999 |
Zhang B, Ganetzky B, Bellen HJ, Murthy VN. Tailoring uniform coats for synaptic vesicles during endocytosis. Neuron. 23: 419-22. PMID 10433253 DOI: 10.1016/S0896-6273(00)80794-1 |
0.631 |
|
| 1999 |
Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY. Math1: an essential gene for the generation of inner ear hair cells. Science (New York, N.Y.). 284: 1837-41. PMID 10364557 DOI: 10.1126/Science.284.5421.1837 |
0.669 |
|
| 1999 |
Bhat MA, Izaddoost S, Lu Y, Cho KO, Choi KW, Bellen HJ. Discs Lost, a novel multi-PDZ domain protein, establishes and maintains epithelial polarity. Cell. 96: 833-45. PMID 10102271 DOI: 10.1016/S0092-8674(00)80593-0 |
0.672 |
|
| 1998 |
Zhang B, Koh YH, Beckstead RB, Budnik V, Ganetzky B, Bellen HJ. Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis. Neuron. 21: 1465-75. PMID 9883738 DOI: 10.1016/S0896-6273(00)80664-9 |
0.774 |
|
| 1998 |
Hassan BA, Prokopenko SN, Breuer S, Zhang B, Paululat A, Bellen HJ. skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release. Genetics. 150: 1527-37. PMID 9832529 |
0.709 |
|
| 1998 |
Bellen HJ, Lu Y, Beckstead R, Bhat MA. Neurexin IV, caspr and paranodin--novel members of the neurexin family: encounters of axons and glia. Trends in Neurosciences. 21: 444-9. PMID 9786343 DOI: 10.1016/S0166-2236(98)01267-3 |
0.713 |
|
| 1998 |
Bellen HJ. The fruit fly: a model organism to study the genetics of alcohol abuse and addiction? Cell. 93: 909-12. PMID 9635419 DOI: 10.1016/S0092-8674(00)81195-2 |
0.301 |
|
| 1998 |
Adams RR, Tavares AA, Salzberg A, Bellen HJ, Glover DM. pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes & Development. 12: 1483-94. PMID 9585508 DOI: 10.1101/Gad.12.10.1483 |
0.621 |
|
| 1998 |
Dye CA, Lee JK, Atkinson RC, Brewster R, Han PL, Bellen HJ. The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development (Cambridge, England). 125: 1845-56. PMID 9550717 |
0.692 |
|
| 1998 |
Wu MN, Littleton JT, Bhat MA, Prokop A, Bellen HJ. ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner. The Embo Journal. 17: 127-39. PMID 9427747 DOI: 10.1093/Emboj/17.1.127 |
0.672 |
|
| 1997 |
Cabello OA, Baldini A, Bhat M, Bellen H, Belmont JW. Localization of BRRN1, the human homologue of Drosophila barr, to 2q11.2 Genomics. 46: 311-313. PMID 9417923 DOI: 10.1006/geno.1997.5021 |
0.481 |
|
| 1997 |
Salzberg A, Prokopenko SN, He Y, Tsai P, Pál M, Maróy P, Glover DM, Deák P, Bellen HJ. P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: mutations affecting embryonic PNS development. Genetics. 147: 1723-41. PMID 9409832 |
0.691 |
|
| 1997 |
Wu MN, Bellen HJ. Genetic dissection of synaptic transmission in Drosophila. Current Opinion in Neurobiology. 7: 624-30. PMID 9384538 DOI: 10.1016/S0959-4388(97)80081-5 |
0.557 |
|
| 1997 |
Ben-Arie N, Bellen HJ, Armstrong DL, McCall AE, Gordadze PR, Guo Q, Matzuk MM, Zoghbi HY. Math1 is essential for genesis of cerebellar granule neurons. Nature. 390: 169-72. PMID 9367153 DOI: 10.1038/36579 |
0.518 |
|
| 1997 |
Littleton JT, Bhat MA, Bellen HJ. Deciphering the function of neurexins at cellular junctions. The Journal of Cell Biology. 137: 793-6. PMID 9151682 DOI: 10.1083/jcb.137.4.793 |
0.545 |
|
| 1996 |
Bhat MA, Philp AV, Glover DM, Bellen HJ. Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II. Cell. 87: 1103-14. PMID 8978614 DOI: 10.1016/S0092-8674(00)81804-8 |
0.573 |
|
| 1996 |
Baumgartner S, Littleton JT, Broadie K, Bhat MA, Harbecke R, Lengyel JA, Chiquet-Ehrismann R, Prokop A, Bellen HJ. A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function. Cell. 87: 1059-68. PMID 8978610 DOI: 10.1016/S0092-8674(00)81800-0 |
0.575 |
|
| 1996 |
Schulze KL, Bellen HJ. Drosophila syntaxin is required for cell viability and may function in membrane formation and stabilization. Genetics. 144: 1713-24. PMID 8978057 |
0.662 |
|
| 1996 |
Salzberg A, Golden K, Bodmer R, Bellen HJ. gutfeeling, a Drosophila gene encoding an antizyme-like protein, is required for late differentiation of neurons and muscles. Genetics. 144: 183-96. PMID 8878684 |
0.617 |
|
| 1996 |
Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY. Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. Human Molecular Genetics. 5: 1207-16. PMID 8872459 DOI: 10.1093/hmg/5.9.1207 |
0.543 |
|
| 1996 |
Salzberg A, Bellen HJ. Invertebrate versus vertebrate neurogenesis: variations on the same theme? Developmental Genetics. 18: 1-10. PMID 8742829 DOI: 10.1002/(SICI)1520-6408(1996)18:1<1::AID-DVG1>3.0.CO;2-D |
0.54 |
|
| 1995 |
Kania A, Bellen HJ. Mutations in neuromusculin, a gene encoding a cell adhesion molecule, cause nervous system defects. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 204: 259-270. PMID 28306121 DOI: 10.1007/BF00208493 |
0.544 |
|
| 1995 |
Littleton JT, Bellen HJ. Presynaptic proteins involved in exocytosis in Drosophila melanogaster: a genetic analysis. Invertebrate Neuroscience : In. 1: 3-13. PMID 9372128 DOI: 10.1007/BF02331827 |
0.375 |
|
| 1995 |
Schulze KL, Broadie K, Perin MS, Bellen HJ. Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell. 80: 311-20. PMID 7834751 DOI: 10.1016/0092-8674(95)90414-X |
0.706 |
|
| 1995 |
Kania A, Salzberg A, Bhat M, D'Evelyn D, He Y, Kiss I, Bellen HJ. P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster. Genetics. 139: 1663-78. PMID 7789767 |
0.748 |
|
| 1995 |
Broadie K, Prokop A, Bellen HJ, O'Kane CJ, Schulze KL, Sweeney ST. Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila. Neuron. 15: 663-73. PMID 7546745 DOI: 10.1016/0896-6273(95)90154-X |
0.687 |
|
| 1995 |
Kania A, Bellen HJ. Mutations in neuromusculin, a gene encoding a cell adhesion molecule, cause nervous system defects Roux's Archives of Developmental Biology. 204: 259-270. DOI: 10.1007/BF00208493 |
0.519 |
|
| 1994 |
Salzberg A, D'Evelyn D, Schulze KL, Lee JK, Strumpf D, Tsai L, Bellen HJ. Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron. 13: 269-87. PMID 8060613 DOI: 10.1016/0896-6273(94)90346-8 |
0.783 |
|
| 1994 |
Schulze KL, Littleton JT, Salzberg A, Halachmi N, Stern M, Lev Z, Bellen HJ. rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo. Neuron. 13: 1099-108. PMID 7946348 DOI: 10.1016/0896-6273(94)90048-5 |
0.764 |
|
| 1994 |
Broadie K, Bellen HJ, DiAntonio A, Littleton JT, Schwarz TL. Absence of synaptotagmin disrupts excitation-secretion coupling during synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. 91: 10727-31. PMID 7938019 DOI: 10.1073/pnas.91.22.10727 |
0.313 |
|
| 1993 |
Kania A, Han PL, Kim YT, Bellen H. Neuromusculin, a Drosophila gene expressed in peripheral neuronal precursors and muscles, encodes a cell adhesion molecule. Neuron. 11: 673-87. PMID 8398154 DOI: 10.1016/0896-6273(93)90078-6 |
0.678 |
|
| 1993 |
Littleton JT, Stern M, Schulze K, Perin M, Bellen HJ. Mutational analysis of Drosophila synaptotagmin demonstrates its essential role in Ca(2+)-activated neurotransmitter release. Cell. 74: 1125-34. PMID 8104705 DOI: 10.1016/0092-8674(93)90733-7 |
0.669 |
|
| 1992 |
Whitehouse-Hills S, Bellen HJ, Kiger JA. Embryonic cAMP and developmental potential in Drosophila melanogaster. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 201: 257-264. PMID 28305849 DOI: 10.1007/BF00188756 |
0.658 |
|
| 1992 |
Bellen HJ, Vaessin H, Bier E, Kolodkin A, D'Evelyn D, Kooyer S, Jan YN. The Drosophila couch potato gene: an essential gene required for normal adult behavior. Genetics. 131: 365-75. PMID 1644278 |
0.731 |
|
| 1992 |
Bellen HJ, Kooyer S, D'Evelyn D, Pearlman J. The Drosophila couch potato protein is expressed in nuclei of peripheral neuronal precursors and shows homology to RNA-binding proteins. Genes & Development. 6: 2125-36. PMID 1427076 DOI: 10.1101/Gad.6.11.2125 |
0.387 |
|
| 1992 |
Whitehouse-Hills S, Bellen HJ, Kiger JA. Embryonic cAMP and developmental potential in Drosophila melanogaster Roux's Archives of Developmental Biology. 201: 257-264. DOI: 10.1007/BF00188756 |
0.645 |
|
| 1990 |
Wilson C, Bellen HJ, Gehring WJ. Position effects on eukaryotic gene expression. Annual Review of Cell Biology. 6: 679-714. PMID 2275824 DOI: 10.1146/annurev.cb.06.110190.003335 |
0.493 |
|
| 1990 |
Bellen HJ, Wilson C, Gehring WJ. Dissecting the complexity of the nervous system by enhancer detection. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 12: 199-204. PMID 2164394 DOI: 10.1002/bies.950120502 |
0.526 |
|
| 1990 |
Bellen HJ, Wilson C, Gibson G, Grossniklaus U, Pearson RK, O'Kane C, Gehring WJ. P-element-mediated enhancer detection allows rapid identification of developmentally regulated genes and cell specific markers in Drosophila. Journal De Physiologie. 84: 33-41. PMID 2162957 |
0.682 |
|
| 1989 |
Wilson C, Pearson RK, Bellen HJ, O'Kane CJ, Grossniklaus U, Gehring WJ. P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. Genes & Development. 3: 1301-13. PMID 2558051 DOI: 10.1101/Gad.3.9.1301 |
0.649 |
|
| 1989 |
Bellen HJ, O'Kane CJ, Wilson C, Grossniklaus U, Pearson RK, Gehring WJ. P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes & Development. 3: 1288-300. PMID 2558050 DOI: 10.1101/Gad.3.9.1288 |
0.639 |
|
| 1989 |
Grossniklaus U, Bellen HJ, Wilson C, Gehring WJ. P-element-mediated enhancer detection applied to the study of oogenesis in Drosophila. Development (Cambridge, England). 107: 189-200. PMID 2517254 |
0.622 |
|
| 1988 |
Bellen HJ, Kiger JA. Maternal effects of general and regional specificity on embryos of Drosophila melanogaster caused by dunce and rutabaga mutant combinations. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 197: 258-268. PMID 28305785 DOI: 10.1007/BF00380019 |
0.667 |
|
| 1987 |
Bellen HJ, Gregory BK, Olsson CL, Kiger JA. Two Drosophila learning mutants, dunce and rutabaga, provide evidence of a maternal role for cAMP on embryogenesis. Developmental Biology. 121: 432-44. PMID 3034702 DOI: 10.1016/0012-1606(87)90180-1 |
0.7 |
|
| 1987 |
Bellen HJ, Kiger JA. Sexual hyperactivity and reduced longevity of dunce females of Drosophila melanogaster. Genetics. 115: 153-60. PMID 3030881 |
0.629 |
|
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