Year |
Citation |
Score |
2007 |
Johnson AA, Marchand C, Patil SS, Costi R, Di Santo R, Burke TR, Pommier Y. Probing HIV-1 integrase inhibitor binding sites with position-specific integrase-DNA cross-linking assays. Molecular Pharmacology. 71: 893-901. PMID 17172465 DOI: 10.1124/Mol.106.030817 |
0.366 |
|
2006 |
Semenova EA, Johnson AA, Marchand C, Pommier Y. Integration of human immunodeficiency virus as a target for antiretroviral therapy. Current Opinion in Hiv and Aids. 1: 380-7. PMID 19372837 DOI: 10.1097/01.Coh.0000239850.14991.F9 |
0.33 |
|
2006 |
Marchand C, Krajewski K, Lee HF, Antony S, Johnson AA, Amin R, Roller P, Kvaratskhelia M, Pommier Y. Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites. Nucleic Acids Research. 34: 5157-65. PMID 16998183 DOI: 10.1093/Nar/Gkl667 |
0.382 |
|
2006 |
Johnson AA, Sayer JM, Yagi H, Patil SS, Debart F, Maier MA, Corey DR, Vasseur JJ, Burke TR, Marquez VE, Jerina DM, Pommier Y. Effect of DNA modifications on DNA processing by HIV-1 integrase and inhibitor binding: role of DNA backbone flexibility and an open catalytic site. The Journal of Biological Chemistry. 281: 32428-38. PMID 16943199 DOI: 10.1074/Jbc.M605101200 |
0.422 |
|
2006 |
Semenova EA, Johnson AA, Marchand C, Davis DA, Yarchoan R, Pommier Y. Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones. Molecular Pharmacology. 69: 1454-60. PMID 16418335 DOI: 10.1124/Mol.105.020321 |
0.326 |
|
2006 |
Johnson AA, Santos W, Pais GC, Marchand C, Amin R, Burke TR, Verdine G, Pommier Y. Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop. The Journal of Biological Chemistry. 281: 461-7. PMID 16257967 DOI: 10.1074/Jbc.M511348200 |
0.404 |
|
2005 |
Pommier Y, Johnson AA, Marchand C. Integrase inhibitors to treat HIV/AIDS. Nature Reviews. Drug Discovery. 4: 236-48. PMID 15729361 DOI: 10.1038/Nrd1660 |
0.305 |
|
2004 |
Feng JY, Murakami E, Zorca SM, Johnson AA, Johnson KA, Schinazi RF, Furman PA, Anderson KS. Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Antimicrobial Agents and Chemotherapy. 48: 1300-6. PMID 15047533 DOI: 10.1128/Aac.48.4.1300-1306.2004 |
0.589 |
|
2004 |
Johnson AA, Sayer JM, Yagi H, Kalena GP, Amin R, Jerina DM, Pommier Y. Position-specific suppression and enhancement of HIV-1 integrase reactions by minor groove benzo[a]pyrene diol epoxide deoxyguanine adducts: implications for molecular interactions between integrase and substrates. The Journal of Biological Chemistry. 279: 7947-55. PMID 14627697 DOI: 10.1074/Jbc.M311263200 |
0.407 |
|
2003 |
Marchand C, Johnson AA, Karki RG, Pais GC, Zhang X, Cowansage K, Patel TA, Nicklaus MC, Burke TR, Pommier Y. Metal-dependent inhibition of HIV-1 integrase by beta-diketo acids and resistance of the soluble double-mutant (F185K/C280S). Molecular Pharmacology. 64: 600-9. PMID 12920196 DOI: 10.1124/Mol.64.3.600 |
0.339 |
|
2002 |
Xu G, Kannan A, Hartman TL, Wargo H, Watson K, Turpin JA, Buckheit RW, Johnson AA, Pommier Y, Cushman M. Synthesis of substituted diarylmethylenepiperidines (DAMPs), a novel class of anti-HIV agents. Bioorganic & Medicinal Chemistry. 10: 2807-16. PMID 12057671 DOI: 10.1016/S0968-0896(02)00095-0 |
0.321 |
|
2001 |
Johnson AA, Ray AS, Hanes J, Suo Z, Colacino JM, Anderson KS, Johnson KA. Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 276: 40847-57. PMID 11526116 DOI: 10.1074/Jbc.M106743200 |
0.645 |
|
2001 |
Johnson AA, Johnson KA. Exonuclease proofreading by human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 276: 38097-107. PMID 11477094 DOI: 10.1074/Jbc.M106046200 |
0.567 |
|
2001 |
Johnson AA, Johnson KA. Fidelity of nucleotide incorporation by human mitochondrial DNA polymerase. The Journal of Biological Chemistry. 276: 38090-6. PMID 11477093 DOI: 10.1074/Jbc.M106045200 |
0.53 |
|
2001 |
Feng JY, Johnson AA, Johnson KA, Anderson KS. Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. The Journal of Biological Chemistry. 276: 23832-7. PMID 11328813 DOI: 10.1074/Jbc.M101156200 |
0.585 |
|
2000 |
Johnson AA, Tsai Yc, Graves SW, Johnson KA. Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization. Biochemistry. 39: 1702-8. PMID 10677218 DOI: 10.1021/Bi992104W |
0.637 |
|
1998 |
Graves SW, Johnson AA, Johnson KA. Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase. Biochemistry. 37: 6050-8. PMID 9558343 DOI: 10.1021/Bi972685U |
0.535 |
|
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