| Year |
Citation |
Score |
| 2014 |
Li W, Ai N, Wang S, Bhattacharya N, Vrbanac V, Collins M, Signoretti S, Hu Y, Boyce FM, Gravdal K, Halvorsen OJ, Nalwoga H, Akslen LA, Harlow E, Watnick RS. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 111: 1521-6. PMID 24434559 DOI: 10.1073/Pnas.1320638111 |
0.33 |
|
| 2014 |
Ai N, Hulsurkar M, Akslen L, Watnick R, Harlow E, Li W. Abstract LB-189: GRK3 is essential for metastatic cells and promotes prostate cancer progression Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-189 |
0.312 |
|
| 2013 |
Demarest SJ, Gardner J, Vendel MC, Ailor E, Szak S, Huang F, Doern A, Tan X, Yang W, Grueneberg DA, Richards EJ, Endege WO, Harlow E, Koopman LA. Evaluation of Tyro3 expression, Gas6-mediated Akt phosphorylation, and the impact of anti-Tyro3 antibodies in melanoma cell lines. Biochemistry. 52: 3102-18. PMID 23570341 DOI: 10.1021/bi301588c |
0.355 |
|
| 2012 |
Ai N, Harlow E, Li W. Abstract LB-90: Essential kinases for human metastatic cells pertaining to c-Met signaling Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-90 |
0.346 |
|
| 2011 |
Tschöp K, Conery AR, Litovchick L, Decaprio JA, Settleman J, Harlow E, Dyson N. A kinase shRNA screen links LATS2 and the pRB tumor suppressor. Genes & Development. 25: 814-30. PMID 21498571 DOI: 10.1101/Gad.2000211 |
0.639 |
|
| 2010 |
Conery AR, Sever S, Harlow E. Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 15461-6. PMID 20713695 DOI: 10.1073/Pnas.1010633107 |
0.303 |
|
| 2010 |
Conery AR, Harlow E. High-throughput screens in diploid cells identify factors that contribute to the acquisition of chromosomal instability. Proceedings of the National Academy of Sciences of the United States of America. 107: 15455-60. PMID 20713694 DOI: 10.1073/pnas.1010627107 |
0.307 |
|
| 2010 |
Baldwin A, Grueneberg DA, Hellner K, Sawyer J, Grace M, Li W, Harlow E, Munger K. Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3. Proceedings of the National Academy of Sciences of the United States of America. 107: 12463-8. PMID 20616055 DOI: 10.1073/Pnas.1007462107 |
0.392 |
|
| 2009 |
Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ. Cyclin-dependent kinases: a family portrait. Nature Cell Biology. 11: 1275-6. PMID 19884882 DOI: 10.1038/Ncb1109-1275 |
0.585 |
|
| 2008 |
Baldwin A, Li W, Grace M, Pearlberg J, Harlow E, Münger K, Grueneberg DA. Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16478-83. PMID 18948598 DOI: 10.1073/Pnas.0806195105 |
0.335 |
|
| 2008 |
Grueneberg DA, Li W, Davies JE, Sawyer J, Pearlberg J, Harlow E. Kinase requirements in human cells: IV. Differential kinase requirements in cervical and renal human tumor cell lines. Proceedings of the National Academy of Sciences of the United States of America. 105: 16490-5. PMID 18948597 DOI: 10.1073/Pnas.0806578105 |
0.382 |
|
| 2008 |
Bommi-Reddy A, Almeciga I, Sawyer J, Geisen C, Li W, Harlow E, Kaelin WG, Grueneberg DA. Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen. Proceedings of the National Academy of Sciences of the United States of America. 105: 16484-9. PMID 18948595 DOI: 10.1073/Pnas.0806574105 |
0.357 |
|
| 2008 |
Grueneberg DA, Degot S, Pearlberg J, Li W, Davies JE, Baldwin A, Endege W, Doench J, Sawyer J, Hu Y, Boyce F, Xian J, Munger K, Harlow E. Kinase requirements in human cells: I. Comparing kinase requirements across various cell types. Proceedings of the National Academy of Sciences of the United States of America. 105: 16472-7. PMID 18948591 DOI: 10.1073/Pnas.0808019105 |
0.381 |
|
| 2007 |
Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, ... ... Harlow E, et al. Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Research. 17: 536-43. PMID 17322287 DOI: 10.1101/Gr.6037607 |
0.352 |
|
| 2006 |
Harlow E, Lane D. Immunoprecipitation: purifying the immune complexes. Csh Protocols. 2006. PMID 22485918 DOI: 10.1101/pdb.prot4536 |
0.331 |
|
| 2006 |
Harlow E, Lane D. Immunoprecipitation: denaturing lysis. Csh Protocols. 2006. PMID 22485916 DOI: 10.1101/pdb.prot4534 |
0.329 |
|
| 2006 |
Harlow E, Lane D. Immunoprecipitation: lysing yeast cells using glass beads. Csh Protocols. 2006. PMID 22485915 DOI: 10.1101/pdb.prot4533 |
0.329 |
|
| 2006 |
Harlow E, Lane D. Lysing tissue-culture cells for immunoprecipitation. Csh Protocols. 2006. PMID 22485913 DOI: 10.1101/pdb.prot4531 |
0.321 |
|
| 2006 |
Harlow E, Lane D. Antibody Addition and Detection for Staining Caenorhabditis elegans. Csh Protocols. 2006. PMID 22485905 DOI: 10.1101/pdb.prot4523 |
0.31 |
|
| 2006 |
Harlow E, Lane D. Immunoblotting: preparing immunoprecipitated proteins. Csh Protocols. 2006. PMID 22485848 DOI: 10.1101/pdb.prot4300 |
0.345 |
|
| 2006 |
Harlow E, Lane D. Immunoblotting: preparing cell lysates. Csh Protocols. 2006. PMID 22485847 DOI: 10.1101/pdb.prot4299 |
0.323 |
|
| 2006 |
Harlow E, Lane D. Fixing suspension cells with paraformaldehyde. Csh Protocols. 2006. PMID 22485843 DOI: 10.1101/pdb.prot4295 |
0.31 |
|
| 2006 |
Harlow E, Lane D. Fixing attached cells in paraformaldehyde. Csh Protocols. 2006. PMID 22485842 DOI: 10.1101/pdb.prot4294 |
0.316 |
|
| 2006 |
Harlow E, Lane D. Attaching suspension cells to slides using a cytocentrifuge. Csh Protocols. 2006. PMID 22485839 DOI: 10.1101/pdb.prot4291 |
0.311 |
|
| 2006 |
Harlow E, Lane D. Growing adherent cells on coverslips or multiwell slides. Csh Protocols. 2006. PMID 22485837 DOI: 10.1101/pdb.prot4289 |
0.3 |
|
| 2006 |
Harlow E, Lane D. Protein Quantitation: UV Detection. Csh Protocols. 2006. PMID 22485683 DOI: 10.1101/pdb.prot4307 |
0.311 |
|
| 2006 |
Harlow E, Lane D. Protein quantitation: bradford spot test. Csh Protocols. 2006. PMID 22485682 DOI: 10.1101/pdb.prot4306 |
0.302 |
|
| 2006 |
Harlow E, Lane D. Antibody purification on protein a or protein g columns. Csh Protocols. 2006. PMID 22485675 DOI: 10.1101/pdb.prot4283 |
0.343 |
|
| 2006 |
Harlow E, Lane D. Staining immunoblots for total protein using India ink. Csh Protocols. 2006. PMID 22485667 DOI: 10.1101/pdb.prot4270 |
0.344 |
|
| 2006 |
Harlow E, Lane D. Staining immunoblots for total protein using ponceau s. Csh Protocols. 2006. PMID 22485666 DOI: 10.1101/pdb.prot4269 |
0.328 |
|
| 2005 |
Pearlberg J, Degot S, Endege W, Park J, Davies J, Gelfand E, Sawyer J, Conery A, Doench J, Li W, Gonzalez L, Boyce FM, Brizuela L, Labaer J, Grueneberg D, ... Harlow E, et al. Screens using RNAi and cDNA expression as surrogates for genetics in mammalian tissue culture cells. Cold Spring Harbor Symposia On Quantitative Biology. 70: 449-59. PMID 16869783 DOI: 10.1101/Sqb.2005.70.047 |
0.359 |
|
| 2005 |
Park J, Hu Y, Murthy TV, Vannberg F, Shen B, Rolfs A, Hutti JE, Cantley LC, Labaer J, Harlow E, Brizuela L. Building a human kinase gene repository: bioinformatics, molecular cloning, and functional validation. Proceedings of the National Academy of Sciences of the United States of America. 102: 8114-9. PMID 15928075 DOI: 10.1073/Pnas.0503141102 |
0.377 |
|
| 2004 |
Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, Harlow E, Kennedy BK. A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America. 101: 9677-82. PMID 15210943 DOI: 10.1073/Pnas.0403250101 |
0.732 |
|
| 2004 |
Barbie DA, Kudlow BA, Frock R, Zhao J, Johnson BR, Dyson N, Harlow E, Kennedy BK. Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit. Molecular and Cellular Biology. 24: 595-607. PMID 14701733 DOI: 10.1128/Mcb.24.2.595-607.2004 |
0.757 |
|
| 2003 |
Kohn MJ, Bronson RT, Harlow E, Dyson NJ, Yamasaki L. Dp1 is required for extra-embryonic development. Development (Cambridge, England). 130: 1295-305. PMID 12588846 DOI: 10.1242/Dev.00355 |
0.621 |
|
| 2002 |
Classon M, Harlow E. The retinoblastoma tumour suppressor in development and cancer. Nature Reviews. Cancer. 2: 910-7. PMID 12459729 DOI: 10.1038/nrc950 |
0.383 |
|
| 2002 |
Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes & Development. 16: 1472-87. PMID 12080086 DOI: 10.1101/Gad.995802 |
0.368 |
|
| 2002 |
Braun P, Hu Y, Shen B, Halleck A, Koundinya M, Harlow E, LaBaer J. Proteome-scale purification of human proteins from bacteria. Proceedings of the National Academy of Sciences of the United States of America. 99: 2654-9. PMID 11880620 DOI: 10.1073/Pnas.042684199 |
0.359 |
|
| 2001 |
Kennedy BK, Liu OW, Dick FA, Dyson N, Harlow E, Vidal M. Histone deacetylase-dependent transcriptional repression by pRB in yeast occurs independently of interaction through the LXCXE binding cleft. Proceedings of the National Academy of Sciences of the United States of America. 98: 8720-5. PMID 11447271 DOI: 10.1073/Pnas.151240898 |
0.672 |
|
| 2001 |
Lai A, Kennedy BK, Barbie DA, Bertos NR, Yang XJ, Theberge MC, Tsai SC, Seto E, Zhang Y, Kuzmichev A, Lane WS, Reinberg D, Harlow E, Branton PE. RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest. Molecular and Cellular Biology. 21: 2918-32. PMID 11283269 DOI: 10.1128/Mcb.21.8.2918-2932.2001 |
0.411 |
|
| 2001 |
Stevenson LF, Kennedy BK, Harlow E. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proceedings of the National Academy of Sciences of the United States of America. 98: 3946-51. PMID 11274415 DOI: 10.1073/Pnas.051013498 |
0.663 |
|
| 2000 |
Kennedy BK, Barbie DA, Classon M, Dyson N, Harlow E. Nuclear organization of DNA replication in primary mammalian cells. Genes & Development. 14: 2855-68. PMID 11090133 DOI: 10.1101/Gad.842600 |
0.607 |
|
| 2000 |
Classon M, Kennedy BK, Mulloy R, Harlow E. Opposing roles of pRB and p107 in adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 97: 10826-31. PMID 10995476 DOI: 10.1073/Pnas.190343597 |
0.397 |
|
| 2000 |
Classon M, Salama S, Gorka C, Mulloy R, Braun P, Harlow E. Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control. Proceedings of the National Academy of Sciences of the United States of America. 97: 10820-5. PMID 10995475 DOI: 10.1073/pnas.190343497 |
0.452 |
|
| 2000 |
Zhao J, Kennedy BK, Lawrence BD, Barbie DA, Matera AG, Fletcher JA, Harlow E. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes & Development. 14: 2283-97. PMID 10995386 DOI: 10.1101/Gad.827700 |
0.361 |
|
| 1999 |
McCaffrey J, Yamasaki L, Dyson NJ, Harlow E, Griep AE. Disruption of retinoblastoma protein family function by human papillomavirus type 16 E7 oncoprotein inhibits lens development in part through E2F-1. Molecular and Cellular Biology. 19: 6458-68. PMID 10454591 DOI: 10.1128/Mcb.19.9.6458 |
0.61 |
|
| 1999 |
Lukas ER, Bartley SM, Graveel CR, Diaz ZM, Dyson N, Harlow E, Yamasaki L, Farnham PJ. No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice. Molecular Carcinogenesis. 25: 295-303. PMID 10449036 DOI: 10.1002/(Sici)1098-2744(199908)25:4<295::Aid-Mc8>3.0.Co;2-9 |
0.576 |
|
| 1998 |
Pan H, Yin C, Dyson NJ, Harlow E, Yamasaki L, Van Dyke T. Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Molecular Cell. 2: 283-92. PMID 9774967 DOI: 10.1016/S1097-2765(00)80273-7 |
0.587 |
|
| 1998 |
Harrington EA, Bruce JL, Harlow E, Dyson N. pRB plays an essential role in cell cycle arrest induced by DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 95: 11945-50. PMID 9751770 DOI: 10.1073/Pnas.95.20.11945 |
0.543 |
|
| 1998 |
Schulman BA, Lindstrom DL, Harlow E. Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A. Proceedings of the National Academy of Sciences of the United States of America. 95: 10453-8. PMID 9724724 DOI: 10.1073/Pnas.95.18.10453 |
0.617 |
|
| 1998 |
Yamasaki L, Bronson R, Williams BO, Dyson NJ, Harlow E, Jacks T. Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice. Nature Genetics. 18: 360-4. PMID 9537419 DOI: 10.1038/Ng0498-360 |
0.597 |
|
| 1998 |
Zhao J, Dynlacht B, Imai T, Hori T, Harlow E. Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes & Development. 12: 456-61. PMID 9472014 DOI: 10.1101/Gad.12.4.456 |
0.37 |
|
| 1997 |
Dynlacht BD, Ngwu C, Winston J, Swindell EC, Elledge SJ, Harlow E, Harper JW. Purification and analysis of CIP/KIP proteins. Methods in Enzymology. 283: 230-44. PMID 9251023 DOI: 10.1016/S0076-6879(97)83019-4 |
0.428 |
|
| 1997 |
Dynlacht BD, Moberg K, Lees JA, Harlow E, Zhu L. Specific regulation of E2F family members by cyclin-dependent kinases. Molecular and Cellular Biology. 17: 3867-75. PMID 9199321 DOI: 10.1128/Mcb.17.7.3867 |
0.386 |
|
| 1997 |
LaBaer J, Garrett MD, Stevenson LF, Slingerland JM, Sandhu C, Chou HS, Fattaey A, Harlow E. New functional activities for the p21 family of CDK inhibitors. Genes & Development. 11: 847-62. PMID 9106657 DOI: 10.1101/Gad.11.7.847 |
0.692 |
|
| 1997 |
Goillot E, Raingeaud J, Ranger A, Tepper RI, Davis RJ, Harlow E, Sanchez I. Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 94: 3302-7. PMID 9096388 DOI: 10.1073/Pnas.94.7.3302 |
0.348 |
|
| 1997 |
Zarkowska T, U S, Harlow E, Mittnacht S. Monoclonal antibodies specific for underphosphorylated retinoblastoma protein identify a cell cycle regulated phosphorylation site targeted by CDKs. Oncogene. 14: 249-54. PMID 9010227 DOI: 10.1038/sj.onc.1200824 |
0.381 |
|
| 1996 |
Magae J, Wu CL, Illenye S, Harlow E, Heintz NH. Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members. Journal of Cell Science. 109: 1717-26. PMID 8832394 |
0.307 |
|
| 1996 |
Vidal M, Braun P, Chen E, Boeke JD, Harlow E. Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system. Proceedings of the National Academy of Sciences of the United States of America. 93: 10321-6. PMID 8816798 DOI: 10.1073/Pnas.93.19.10321 |
0.55 |
|
| 1996 |
Vidal M, Brachmann RK, Fattaey A, Harlow E, Boeke JD. Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions. Proceedings of the National Academy of Sciences of the United States of America. 93: 10315-20. PMID 8816797 DOI: 10.1073/Pnas.93.19.10315 |
0.562 |
|
| 1996 |
Zukerberg LR, Benedict WF, Arnold A, Dyson N, Harlow E, Harris NL. Expression of the retinoblastoma protein in low-grade B-cell lymphoma: relationship to cyclin D1. Blood. 88: 268-76. PMID 8704183 DOI: 10.1182/Blood.V88.1.268.268 |
0.612 |
|
| 1996 |
Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes & Development. 10: 1633-44. PMID 8682294 DOI: 10.1101/Gad.10.13.1633 |
0.594 |
|
| 1996 |
Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T. Targeted disruption of p107: functional overlap between p107 and Rb. Genes & Development. 10: 1621-32. PMID 8682293 DOI: 10.1101/Gad.10.13.1621 |
0.573 |
|
| 1996 |
Wu CL, Classon M, Dyson N, Harlow E. Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1. Molecular and Cellular Biology. 16: 3698-706. PMID 8668186 DOI: 10.1128/Mcb.16.7.3698 |
0.624 |
|
| 1996 |
Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell. 85: 537-48. PMID 8653789 DOI: 10.1016/S0092-8674(00)81254-4 |
0.591 |
|
| 1995 |
Koh J, Enders GH, Dynlacht BD, Harlow E. Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature. 375: 506-10. PMID 7777061 DOI: 10.1038/375506A0 |
0.438 |
|
| 1995 |
Zhu L, Enders G, Lees JA, Beijersbergen RL, Bernards R, Harlow E. The pRB-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes. The Embo Journal. 14: 1904-13. PMID 7743997 DOI: 10.1002/J.1460-2075.1995.Tb07182.X |
0.4 |
|
| 1995 |
Wu CL, Zukerberg LR, Ngwu C, Harlow E, Lees JA. In vivo association of E2F and DP family proteins. Molecular and Cellular Biology. 15: 2536-46. PMID 7739537 DOI: 10.1128/Mcb.15.5.2536 |
0.418 |
|
| 1995 |
Wade M, Blake MC, Jambou RC, Helin K, Harlow E, Azizkhan JC. An inverted repeat motif stabilizes binding of E2F and enhances transcription of the dihydrofolate reductase gene. The Journal of Biological Chemistry. 270: 9783-91. PMID 7730357 DOI: 10.1074/jbc.270.17.9783 |
0.347 |
|
| 1995 |
Zhu L, Harlow E, Dynlacht BD. p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes & Development. 9: 1740-52. PMID 7622038 DOI: 10.1101/Gad.9.14.1740 |
0.397 |
|
| 1994 |
Mittnacht S, Lees JA, Desai D, Harlow E, Morgan DO, Weinberg RA. Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation. The Embo Journal. 13: 118-27. PMID 8306955 DOI: 10.1002/J.1460-2075.1994.Tb06241.X |
0.406 |
|
| 1994 |
Meyerson M, Harlow E. Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Molecular and Cellular Biology. 14: 2077-86. PMID 8114739 DOI: 10.1128/Mcb.14.3.2077 |
0.378 |
|
| 1994 |
Tsai LH, Delalle I, Caviness VS, Chae T, Harlow E. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature. 371: 419-23. PMID 8090221 DOI: 10.1038/371419A0 |
0.555 |
|
| 1994 |
Helin K, Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 is required for binding to the adenovirus E4 (ORF6/7) protein. Journal of Virology. 68: 5027-35. PMID 8035503 DOI: 10.1128/Jvi.68.8.5027-5035.1994 |
0.403 |
|
| 1994 |
Dynlacht BD, Flores O, Lees JA, Harlow E. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes & Development. 8: 1772-86. PMID 7958856 DOI: 10.1101/Gad.8.15.1772 |
0.411 |
|
| 1994 |
Zhu L, Enders GH, Wu CL, Starz MA, Moberg KH, Lees JA, Dyson N, Harlow E. Growth suppression by members of the retinoblastoma protein family. Cold Spring Harbor Symposia On Quantitative Biology. 59: 75-84. PMID 7587134 DOI: 10.1101/Sqb.1994.059.01.011 |
0.563 |
|
| 1993 |
Tsai LH, Lees E, Faha B, Harlow E, Riabowol K. The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene. 8: 1593-602. PMID 8502482 |
0.501 |
|
| 1993 |
Lees EM, Harlow E. Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase. Molecular and Cellular Biology. 13: 1194-201. PMID 8423786 DOI: 10.1128/Mcb.13.2.1194 |
0.384 |
|
| 1993 |
Fattaey AR, Helin K, Dembski MS, Dyson N, Harlow E, Vuocolo GA, Hanobik MG, Haskell KM, Oliff A, Defeo-Jones D. Characterization of the retinoblastoma binding proteins RBP1 and RBP2. Oncogene. 8: 3149-56. PMID 8414517 |
0.314 |
|
| 1993 |
Helin K, Harlow E, Fattaey A. Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein. Molecular and Cellular Biology. 13: 6501-8. PMID 8413249 DOI: 10.1128/Mcb.13.10.6501 |
0.425 |
|
| 1993 |
Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C, Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes & Development. 7: 1850-61. PMID 8405995 DOI: 10.1101/Gad.7.10.1850 |
0.419 |
|
| 1993 |
Faha B, Harlow E, Lees E. The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2. Journal of Virology. 67: 2456-65. PMID 8386263 DOI: 10.1128/Jvi.67.5.2456-2465.1993 |
0.435 |
|
| 1993 |
Zhu L, van den Heuvel S, Helin K, Fattaey A, Ewen M, Livingston D, Dyson N, Harlow E. Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. Genes & Development. 7: 1111-25. PMID 8319904 DOI: 10.1101/Gad.7.7A.1111 |
0.632 |
|
| 1993 |
Tsai LH, Takahashi T, Caviness VS, Harlow E. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development (Cambridge, England). 119: 1029-40. PMID 8306873 |
0.493 |
|
| 1993 |
van den Heuvel S, Harlow E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science (New York, N.Y.). 262: 2050-4. PMID 8266103 DOI: 10.1126/Science.8266103 |
0.394 |
|
| 1993 |
Lees JA, Saito M, Vidal M, Valentine M, Look T, Harlow E, Dyson N, Helin K. The retinoblastoma protein binds to a family of E2F transcription factors. Molecular and Cellular Biology. 13: 7813-25. PMID 8246996 DOI: 10.1128/Mcb.13.12.7813 |
0.712 |
|
| 1993 |
Fattaey AR, Harlow E, Helin K. Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes. Molecular and Cellular Biology. 13: 7267-77. PMID 8246949 DOI: 10.1128/Mcb.13.12.7267 |
0.427 |
|
| 1993 |
Fattaey A, Helin K, Harlow E. Transcriptional inhibition by the retinoblastoma protein. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 340: 333-6. PMID 8103936 DOI: 10.1098/rstb.1993.0075 |
0.451 |
|
| 1992 |
Meyerson M, Enders GH, Wu CL, Su LK, Gorka C, Nelson C, Harlow E, Tsai LH. A family of human cdc2-related protein kinases. The Embo Journal. 11: 2909-17. PMID 1639063 DOI: 10.1002/J.1460-2075.1992.Tb05360.X |
0.593 |
|
| 1992 |
Helin K, Lees JA, Vidal M, Dyson N, Harlow E, Fattaey A. A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell. 70: 337-50. PMID 1638634 DOI: 10.1016/0092-8674(92)90107-N |
0.706 |
|
| 1992 |
Hu QJ, Lees JA, Buchkovich KJ, Harlow E. The retinoblastoma protein physically associates with the human cdc2 kinase. Molecular and Cellular Biology. 12: 971-80. PMID 1545827 DOI: 10.1128/Mcb.12.3.971 |
0.404 |
|
| 1992 |
Dyson N, Guida P, McCall C, Harlow E. Adenovirus E1A makes two distinct contacts with the retinoblastoma protein. Journal of Virology. 66: 4606-11. PMID 1534854 DOI: 10.1128/Jvi.66.7.4606-4611.1992 |
0.565 |
|
| 1992 |
Faha B, Ewen ME, Tsai LH, Livingston DM, Harlow E. Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science (New York, N.Y.). 255: 87-90. PMID 1532458 DOI: 10.1126/Science.1532458 |
0.617 |
|
| 1992 |
Ewen ME, Faha B, Harlow E, Livingston DM. Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science (New York, N.Y.). 255: 85-7. PMID 1532457 DOI: 10.1126/Science.1532457 |
0.399 |
|
| 1992 |
Cao L, Faha B, Dembski M, Tsai LH, Harlow E, Dyson N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature. 355: 176-9. PMID 1530885 DOI: 10.1038/355176A0 |
0.722 |
|
| 1992 |
Lees E, Faha B, Dulic V, Reed SI, Harlow E. Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner. Genes & Development. 6: 1874-85. PMID 1398067 DOI: 10.1101/GAD.6.10.1874 |
0.382 |
|
| 1992 |
Dyson N, Guida P, Münger K, Harlow E. Homologous sequences in adenovirus E1A and human papillomavirus E7 proteins mediate interaction with the same set of cellular proteins. Journal of Virology. 66: 6893-902. PMID 1331501 DOI: 10.1128/Jvi.66.12.6893-6902.1992 |
0.637 |
|
| 1992 |
Meyerson M, Enders G, Wu C, Su L, Gorka C, Nelson C, Harlow E, Tsai L. A family of human cdc2-related protein kinases. The Embo Journal. 11: 2909-2917. DOI: 10.1002/j.1460-2075.1992.tb05360.x |
0.466 |
|
| 1991 |
Larose A, Dyson N, Sullivan M, Harlow E, Bastin M. Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization. Journal of Virology. 65: 2308-13. PMID 2016761 DOI: 10.1128/Jvi.65.5.2308-2313.1991 |
0.587 |
|
| 1991 |
Meyerson M, Faha B, Su LK, Harlow E, Tsai LH. The cyclin-dependent kinase family. Cold Spring Harbor Symposia On Quantitative Biology. 56: 177-86. PMID 1840251 DOI: 10.1101/Sqb.1991.056.01.023 |
0.491 |
|
| 1991 |
Herrmann CH, Su LK, Harlow E. Adenovirus E1A is associated with a serine/threonine protein kinase. Journal of Virology. 65: 5848-59. PMID 1833561 DOI: 10.1128/Jvi.65.11.5848-5859.1991 |
0.383 |
|
| 1991 |
Lees JA, Buchkovich KJ, Marshak DR, Anderson CW, Harlow E. The retinoblastoma protein is phosphorylated on multiple sites by human cdc2. The Embo Journal. 10: 4279-90. PMID 1756735 DOI: 10.1002/J.1460-2075.1991.Tb05006.X |
0.409 |
|
| 1991 |
Hu QJ, Bautista C, Edwards GM, Defeo-Jones D, Jones RE, Harlow E. Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides. Molecular and Cellular Biology. 11: 5792-9. PMID 1717832 DOI: 10.1128/Mcb.11.11.5792 |
0.438 |
|
| 1991 |
Giordano A, Lee JH, Scheppler JA, Herrmann C, Harlow E, Deuschle U, Beach D, Franza BR. Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A. Science (New York, N.Y.). 253: 1271-5. PMID 1653969 DOI: 10.1126/Science.1653969 |
0.453 |
|
| 1991 |
Tsai LH, Harlow E, Meyerson M. Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature. 353: 174-7. PMID 1653904 DOI: 10.1038/353174A0 |
0.595 |
|
| 1990 |
Lee CC, Craigen WJ, Muzny DM, Harlow E, Caskey CT. Cloning and expression of a mammalian peptide chain release factor with sequence similarity to tryptophanyl-tRNA synthetases. Proceedings of the National Academy of Sciences of the United States of America. 87: 3508-12. PMID 2185472 DOI: 10.1073/Pnas.87.9.3508 |
0.324 |
|
| 1990 |
Dyson N, Bernards R, Friend SH, Gooding LR, Hassell JA, Major EO, Pipas JM, Vandyke T, Harlow E. Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. Journal of Virology. 64: 1353-6. PMID 2154613 DOI: 10.1128/Jvi.64.3.1353-1356.1990 |
0.597 |
|
| 1990 |
Buchkovich K, Dyson N, Whyte P, Harlow E. Cellular proteins that are targets for transformation by DNA tumour viruses. Ciba Foundation Symposium. 150: 262-71; discussion 2. PMID 2142644 |
0.342 |
|
| 1990 |
Hu QJ, Dyson N, Harlow E. The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations. The Embo Journal. 9: 1147-55. PMID 2138977 DOI: 10.1002/J.1460-2075.1990.Tb08221.X |
0.642 |
|
| 1989 |
Buchkovich K, Duffy LA, Harlow E. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell. 58: 1097-105. PMID 2673543 DOI: 10.1016/0092-8674(89)90508-4 |
0.434 |
|
| 1989 |
Giordano A, Whyte P, Harlow E, Franza BR, Beach D, Draetta G. A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells. Cell. 58: 981-90. PMID 2570639 DOI: 10.1016/0092-8674(89)90949-5 |
0.432 |
|
| 1989 |
Münger K, Werness BA, Dyson N, Phelps WC, Harlow E, Howley PM. Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. The Embo Journal. 8: 4099-105. PMID 2556261 DOI: 10.1002/J.1460-2075.1989.Tb08594.X |
0.56 |
|
| 1989 |
Dyson N, Buchkovich K, Whyte P, Harlow E. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell. 58: 249-55. PMID 2546678 DOI: 10.1016/0092-8674(89)90839-8 |
0.597 |
|
| 1989 |
Dyson N, Howley PM, Münger K, Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science (New York, N.Y.). 243: 934-7. PMID 2537532 DOI: 10.1126/Science.2537532 |
0.61 |
|
| 1989 |
Horowitz JM, Yandell DW, Park SH, Canning S, Whyte P, Buchkovich K, Harlow E, Weinberg RA, Dryja TP. Point mutational inactivation of the retinoblastoma antioncogene. Science (New York, N.Y.). 243: 937-40. PMID 2521957 DOI: 10.1126/Science.2521957 |
0.364 |
|
| 1989 |
Whyte P, Williamson NM, Harlow E. Cellular targets for transformation by the adenovirus E1A proteins. Cell. 56: 67-75. PMID 2521301 DOI: 10.1016/0092-8674(89)90984-7 |
0.367 |
|
| 1988 |
Whyte P, Buchkovich KJ, Horowitz JM, Friend SH, Raybuck M, Weinberg RA, Harlow E. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature. 334: 124-9. PMID 2968522 DOI: 10.1038/334124A0 |
0.389 |
|
| 1988 |
Horowitz JM, Friend SH, Weinberg RA, Whyte P, Buchkovich K, Harlow E. Anti-oncogenes and the negative regulation of cell growth. Cold Spring Harbor Symposia On Quantitative Biology. 53: 843-7. PMID 2908198 DOI: 10.1101/Sqb.1988.053.01.096 |
0.358 |
|
| 1986 |
Harlow E, Whyte P, Franza BR, Schley C. Association of adenovirus early-region 1A proteins with cellular polypeptides. Molecular and Cellular Biology. 6: 1579-89. PMID 2431282 DOI: 10.1128/Mcb.6.5.1579 |
0.34 |
|
| 1985 |
Harlow E, Williamson NM, Ralston R, Helfman DM, Adams TE. Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53. Molecular and Cellular Biology. 5: 1601-10. PMID 3894933 DOI: 10.1128/mcb.5.7.1601-1610.1985 |
0.315 |
|
| 1985 |
Harlow E, Franza BR, Schley C. Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products. Journal of Virology. 55: 533-46. PMID 3894685 DOI: 10.1128/Jvi.55.3.533-546.1985 |
0.346 |
|
| 1983 |
Leppard K, Totty N, Waterfield M, Harlow E, Jenkins J, Crawford L. Purification and partial amino acid sequence analysis of the cellular tumour antigen, p53, from mouse SV40-transformed cells. The Embo Journal. 2: 1993-9. PMID 6315411 DOI: 10.1002/J.1460-2075.1983.Tb01690.X |
0.301 |
|
| 1982 |
Lane D, Harlow E. Two different viral transforming proteins bind the same host tumour antigen. Nature. 298: 517. PMID 7048105 DOI: 10.1038/298517A0 |
0.321 |
|
| 1982 |
Crawford L, Leppard K, Lane D, Harlow E. Cellular proteins reactive with monoclonal antibodies directed against simian virus 40 T-antigen. Journal of Virology. 42: 612-20. PMID 6177872 DOI: 10.1128/Jvi.42.2.612-620.1982 |
0.335 |
|
| 1981 |
McCormick F, Clark R, Harlow E, Tjian R. SV40 T antigen binds specifically to a cellular 53 K protein in vitro. Nature. 292: 63-5. PMID 6268984 DOI: 10.1038/292063A0 |
0.345 |
|
| 1981 |
Harlow E, Pim DC, Crawford LV. Complex of simian virus 40 large-T antigen and host 53,000-molecular-weight protein in monkey cells. Journal of Virology. 37: 564-73. PMID 6163871 DOI: 10.1128/Jvi.37.2.564-573.1981 |
0.363 |
|
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